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List of works by Michael P Carty

Activation of DNA damage response pathways in human mesenchymal stem cells exposed to cisplatin or γ-irradiation ⬇️

scientific article published on November 1, 2011

Analysis of mutations induced by replication of UV-damaged plasmid DNA in HeLa cell extracts

scientific article published on 01 January 1995

Anti-Cancer Activity of Phenyl and Pyrid-2-yl 1,3-Substituted Benzo[1,2,4]triazin-7-ones and Stable Free Radical Precursors.

scientific article published on 3 March 2018

COMPARE analysis of the toxicity of an iminoquinone derivative of the imidazo[5,4-f]benzimidazoles with NAD(P)H:quinone oxidoreductase 1 (NQO1) activity and computational docking of quinones as NQO1 substrates.

scientific article

Complete replication of plasmid DNA containing a single UV-induced lesion in human cell extracts

scientific article published on 01 April 1996

DNA polymerase alpha from HeLa cells synthesizes DNA with high fidelity in a reconstituted replication system

scientific article published on 01 October 1990

DNA polymerase eta, a key protein in translesion synthesis in human cells.

scientific article

DNA polymerase η modulates replication fork progression and DNA damage responses in platinum-treated human cells

scientific article published on 20 November 2013

Discovery of anti-cancer activity for benzo[1,2,4]triazin-7-ones: Very strong correlation to pleurotin and thioredoxin reductase inhibition

scientific article published on 30 May 2016

Doxorubicin induces the DNA damage response in cultured human mesenchymal stem cells.

scientific article

Effects of titanocene dichloride derivatives on prostate cancer cells, specifically DNA damage-induced apoptosis.

scientific article published on February 2011

Enhanced DNA-PK-mediated RPA2 hyperphosphorylation in DNA polymerase eta-deficient human cells treated with cisplatin and oxaliplatin

scientific article

Expression of ATM in ataxia telangiectasia fibroblasts rescues defects in DNA double-strand break repair in nuclear extracts.

scientific article published on January 2001

First synthesis of an aziridinyl fused pyrrolo[1,2-a]benzimidazole and toxicity evaluation towards normal and breast cancer cell lines.

scientific article

HeLa cell single-stranded DNA-binding protein increases the accuracy of DNA synthesis by DNA polymerase alpha in vitro.

scientific article

HuCOP1 contributes to the regulation of DNA repair in keratinocytes.

scientific article published on 19 December 2016

In vitro replication and mutagenesis of a novel reversion vector with selective DNA damage in the supF gene.

scientific article

Insights into UV-induced apoptosis: ultrastructure, trichrome stain and spectral imaging

scientific article published on 01 January 2002

Ionizing radiation-dependent and independent phosphorylation of the 32-kDa subunit of replication protein A during mitosis

scientific article published on 11 August 2009

N-Alkyl-1,5-dideoxy-1,5-imino-l-fucitols as fucosidase inhibitors: Synthesis, molecular modelling and activity against cancer cell lines

scientific article published on 04 December 2018

New aromatic monoesters of alpha-aminoaralkylphosphonic acids as inhibitors of aminopeptidase N/CD13.

scientific article published on March 2010

One-pot double intramolecular homolytic aromatic substitution routes to dialicyclic ring fused imidazobenzimidazolequinones and preliminary analysis of anticancer activity

scientific article

RPA phosphorylation in mitosis alters DNA binding and protein-protein interactions.

scientific article

Selective Methylmagnesium Chloride Mediated Acetylations of Isosorbide: A Route to Powerful Nitric Oxide Donor Furoxans

scientific article published on 26 April 2018

Simian virus 40 (SV40) small t antigen inhibits SV40 DNA replication in vitro ⬇️

scientific article published on March 1, 1992

Synthesis and toxicity towards normal and cancer cell lines of benzimidazolequinones containing fused aromatic rings and 2-aromatic ring substituents.

scientific article published on 19 May 2010

Synthesis by radical cyclization and cytotoxicity of highly potent bioreductive alicyclic ring fused [1,2-a]benzimidazolequinones

scientific article published on January 2007

The human POLH gene is not mutated, and is expressed in a cohort of patients with basal or squamous cell carcinoma of the skin.

scientific article

The influence of the aziridinyl substituent of benzimidazoles and benzimidazolequinones on toxicity towards normal and Fanconi anaemia cells.

scientific article published on 20 January 2010

The morphological and spectral phenotype of apoptosis in HeLa cells varies following exposure to UV-C and the addition of inhibitors of ICE and CPP32.

scientific article published in February 1998

UV-induced RPA phosphorylation is increased in the absence of DNA polymerase eta and requires DNA-PK.

scientific article

UV-induced hyperphosphorylation of replication protein a depends on DNA replication and expression of ATM protein.

scientific article

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