List of works - Mark S Hipp

A protein quality control pathway regulated by linear ubiquitination

scientific article published on 18 March 2019

Author Correction: Gel-like inclusions of C-terminal fragments of TDP-43 sequester stalled proteasomes in neurons

scientific article published on 7 June 2024

Cell-to-cell transmission of C9orf72 poly-(Gly-Ala) triggers key features of ALS/FTD

scientific article published on 16 March 2020

Cytoplasmic protein aggregates interfere with nucleocytoplasmic transport of protein and RNA.

scientific article published on 3 December 2015

Fluc‐EGFP reporter mice reveal differential alterations of neuronal proteostasis in aging and disease

scientific article published on 19 August 2021

Functional Modules of the Proteostasis Network

scientific article published on 02 January 2020

Gel‐like inclusions of C‐terminal fragments of TDP‐43 sequester stalled proteasomes in neurons

scientific article published on 19 April 2022

High capacity of the endoplasmic reticulum to prevent secretion and aggregation of amyloidogenic proteins.

scientific article published on 15 December 2017

In Situ Architecture and Cellular Interactions of PolyQ Inclusions

scientific article published on 29 August 2017

In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment.

scientific article published on 31 January 2018

In situ architecture of neuronal α-Synuclein inclusions

scientific article published on 14 April 2021

Live-Cell Imaging of Ubiquitin–Proteasome System Function ⬇️

scientific article published on January 1, 2012

Molecular chaperone functions in protein folding and proteostasis

scientific article

Multiple pathways of toxicity induced by C9orf72 dipeptide repeat aggregates and G4C2 RNA in a cellular model

scientific article published on 23 June 2021

Nuclear inclusion bodies of mutant and wild-type p53 in cancer: a hallmark of p53 inactivation and proteostasis remodelling by p53 aggregation.

scientific article published on 30 December 2016

PolyQ proteins interfere with nuclear degradation of cytosolic proteins by sequestering the Sis1p chaperone

scientific article

Proteasome inhibition leads to NF-kappaB-independent IL-8 transactivation in human endothelial cells through induction of AP-1.

scientific article

Proteotoxic stress and ageing triggers the loss of redox homeostasis across cellular compartments

scientific article

Role for ribosome-associated quality control in sampling proteins for MHC class I-mediated antigen presentation

scientific article published on 11 February 2020

Sis1 potentiates the stress response to protein aggregation and elevated temperature

scientific article published on 08 December 2020

Spatiotemporal Proteomic Profiling of Huntington's Disease Inclusions Reveals Widespread Loss of Protein Function.

scientific article published in November 2017

The endoplasmic reticulum: A hub of protein quality control in health and disease

scientific article published on 28 March 2017

The extracellular chaperone Clusterin enhances Tau aggregate seeding in a cellular model

scientific article published on 11 August 2021

The nucleolus functions as a phase-separated protein quality control compartment

scientific article

The proteostasis network and its decline in ageing

scientific article published on 01 July 2019

Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway: a potential role for protein aggregation in autophagic substrate selection

scientific article

List of works by Mark S Hipp

A protein quality control pathway regulated by linear ubiquitination

Author Correction: Gel-like inclusions of C-terminal fragments of TDP-43 sequester stalled proteasomes in neurons

Cell-to-cell transmission of C9orf72 poly-(Gly-Ala) triggers key features of ALS/FTD

Cytoplasmic protein aggregates interfere with nucleocytoplasmic transport of protein and RNA.

Fluc‐EGFP reporter mice reveal differential alterations of neuronal proteostasis in aging and disease

Functional Modules of the Proteostasis Network

Gel‐like inclusions of C‐terminal fragments of TDP‐43 sequester stalled proteasomes in neurons

High capacity of the endoplasmic reticulum to prevent secretion and aggregation of amyloidogenic proteins.

In Situ Architecture and Cellular Interactions of PolyQ Inclusions

In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment.

In situ architecture of neuronal α-Synuclein inclusions

Live-Cell Imaging of Ubiquitin–Proteasome System Function ⬇️

Molecular chaperone functions in protein folding and proteostasis

Multiple pathways of toxicity induced by C9orf72 dipeptide repeat aggregates and G4C2 RNA in a cellular model

Nuclear inclusion bodies of mutant and wild-type p53 in cancer: a hallmark of p53 inactivation and proteostasis remodelling by p53 aggregation.

PolyQ proteins interfere with nuclear degradation of cytosolic proteins by sequestering the Sis1p chaperone

Proteasome inhibition leads to NF-kappaB-independent IL-8 transactivation in human endothelial cells through induction of AP-1.

Proteotoxic stress and ageing triggers the loss of redox homeostasis across cellular compartments

Role for ribosome-associated quality control in sampling proteins for MHC class I-mediated antigen presentation

Sis1 potentiates the stress response to protein aggregation and elevated temperature

Spatiotemporal Proteomic Profiling of Huntington's Disease Inclusions Reveals Widespread Loss of Protein Function.

The endoplasmic reticulum: A hub of protein quality control in health and disease

The extracellular chaperone Clusterin enhances Tau aggregate seeding in a cellular model

The nucleolus functions as a phase-separated protein quality control compartment

The proteostasis network and its decline in ageing

Ubiquitin accumulation in autophagy-deficient mice is dependent on the Nrf2-mediated stress response pathway: a potential role for protein aggregation in autophagic substrate selection