List of works - Reza Yousefi

A Comparative Study of the Impact of Calcium Ion on Structure, Aggregation and Chaperone Function of Human αA-crystallin and its Cataract- Causing R12C Mutant.

scientific article published on 7 August 2017

A new aspect to chaperone-like activity of bovine β-casein by protein-protein interactions study.

scientific article published on 9 August 2012

Aggregation and fibrillation of eye lens crystallins by homocysteinylation; implication in the eye pathological disorders.

scientific article published in December 2012

Aggregation and structural changes of α(S1)-, β- and κ-caseins induced by homocysteinylation.

scientific article published on 12 June 2011

An in vitro study of the role of β-boswellic acid in the microtubule assembly dynamics

scientific article published on 23 October 2012

Anticancer activity and DNA-binding properties of novel cationic Pt(II) complexes.

scientific article published on 12 February 2014

Anticancer activity assessment of two novel binuclear platinum (II) complexes.

scientific article published on 2 June 2016

Anticancer and DNA binding activities of platinum (IV) complexes; importance of leaving group departure rate

scientific article published on 12 January 2014

Aspirin-mediated acetylation induces structural alteration and aggregation of bovine pancreatic insulin

scientific article

Assessment of structure, stability and aggregation of soluble lens proteins and alpha-crystallin upon non-enzymatic glycation: The pathomechanisms underlying cataract development in diabetic patients

scientific article published on 15 October 2015

Binding study of novel anti-diabetic pyrimidine fused heterocycles to β-lactoglobulin as a carrier protein.

scientific article

Biological activity of camel milk casein following enzymatic digestion

scientific article published on 13 September 2011

Chaperone activities of bovine and camel beta-caseins: Importance of their surface hydrophobicity in protection against alcohol dehydrogenase aggregation.

scientific article published on 7 February 2008

Chaperone-like activities of different molecular forms of beta-casein. Importance of polarity of N-terminal hydrophilic domain

scientific article published on August 2009

Chemical modifications of insulin: Finding a compromise between stability and pharmaceutical performance

scientific article published on 08 June 2018

Chemometric study of the aggregation of alcohol dehydrogenase and its suppression by beta-caseins: a mechanistic perspective.

scientific article published on 23 February 2008

Comparative study on the interaction of two binuclear Pt (II) complexes with human serum albumin: Spectroscopic and docking simulation assessments

scientific article published on 30 September 2016

Dual behavior of sodium dodecyl sulfate as enhancer or suppressor of insulin aggregation and chaperone-like activity of camel alphaS(1)-casein.

scientific article published on 31 August 2009

Effect of homocysteine thiolactone on structure and aggregation propensity of bovine pancreatic insulin

scientific article published on 01 June 2011

Effect of homocysteinylation on structure, chaperone activity and fibrillation propensity of lens alpha-crystallin.

scientific article

Effect of salts and sodium dodecyl sulfate on chaperone activity of camel alphaS(1)-CN: insulin as the target protein.

scientific article

Effect of temperature and ionic strength on structure and chaperone activity of glycated and non-glycated alpha-crystallins

scientific article published on 01 April 2012

Evaluation of Structure, Chaperone-Like Activity and Allergenicity of Reduced Glycated Adduct of Bovine β-casein

scientific article published on 21 November 2016

Evaluation of structure, chaperone-like activity and protective ability of peroxynitrite modified human α-Crystallin subunits against copper-mediated ascorbic acid oxidation.

scientific article

Fibril formation of lysozyme upon interaction with sodium dodecyl sulfate at pH 9.2.

scientific article published on 02 June 2007

Human αB-crystallin as fusion protein and molecular chaperone increases the expression and folding efficiency of recombinant insulin

scientific article published in PLoS ONE

Importance of the positively charged residue at position 54 to the chaperoning function, conformational stability and amyloidogenic nature of human αA-crystallin.

scientific article published on 23 October 2017

Interaction of prodigiosin with HSA and β-Lg: Spectroscopic and molecular docking studies.

scientific article published on 16 February 2016

Potassium sorbate as an AGE activator for human serum albumin in the presence and absence of glucose

scientific article published on 31 August 2013

Preventive role of lens antioxidant defense mechanism against riboflavin-mediated sunlight damaging of lens crystallins.

scientific article published on 14 June 2016

Protective Effects of Acetylation on the Pathological Reactions of the Lens Crystallins with Homocysteine Thiolactone.

scientific article

Protective effects of carnosine on dehydroascorbate-induced structural alteration and opacity of lens crystallins: important implications of carnosine pleiotropic functions to combat cataractogenesis.

scientific article

Protective role of antioxidant compounds against peroxynitrite-mediated modification of R54C mutant αA-crystallin.

scientific article published on 15 July 2017

Pyrimidine-fused heterocycle derivatives as a novel class of inhibitors for α-glucosidase

scientific article published on 08 October 2012

Structural analysis and aggregation propensity of reduced and nonreduced glycated insulin adducts.

scientific article published on 14 April 2013

Structural and functional alteration of human αA-crystallin after exposure to full spectrum solar radiation and preventive role of lens antioxidants

scientific article published on 30 June 2018

Structural changes and aggregation process of Cu/containing amine oxidase in the presence of 2,2,2'-trifluoroethanol.

scientific article

Structure, Chaperone Activity, and Aggregation of Wild-Type and R12C Mutant αB-Crystallins in the Presence of Thermal Stress and Calcium Ion - Implications for Role of Calcium in Cataract Pathogenesis.

scientific article published in February 2016

Structure, chaperone-like activity and allergenicity profile of bovine caseins upon peroxynitrite modification: New evidences underlying mastitis pathomechanisms

scientific article

Studies to reveal the nature of interactions between catalase and curcumin using computational methods and optical techniques.

scientific article published on 16 November 2016

Synthesis and Antioxidant Activity Evaluation of Some Novel Aminocarbonitrile Derivatives Incorporating Carbohydrate Moieties

scientific article published on 31 August 2018

Synthesis and characterization of some new Schiff base complexes of group 13 elements, ab initio studies, cytotoxicity and reaction with hydrogen peroxide.

scientific article

Synthesis of novel poly-hydroxyl functionalized acridine derivatives as inhibitors of α-Glucosidase and α-Amylase

scientific article published on 18 April 2015

The anticancer activity and HSA binding properties of the structurally related platinum (II) complexes.

scientific article published on 24 May 2012

The congenital cataract-causing mutations P20R and A171T are associated with important changes in the amyloidogenic feature, structure and chaperone-like activity of human αB-crystallin

scientific article published on 28 February 2020

The enhancement effect of beta-boswellic acid on hippocampal neurites outgrowth and branching (an in vitro study).

scientific article published on 9 March 2010

The enhancing effect of homocysteine thiolactone on insulin fibrillation and cytotoxicity of insulin fibril.

scientific article published on 23 May 2012

The impact of Hydrogen peroxide on structure, stability and functional properties of Human R12C mutant αA-crystallin: The imperative insights into pathomechanism of the associated congenital cataract incidence

scientific article published on 12 October 2015

The impact of calcium ion on structure and aggregation propensity of peroxynitrite-modified lens crystallins: new insights into the pathogenesis of cataract disorders

scientific article

The impact of different mutations at Arg54 on structure, chaperone-like activity and oligomerization state of human αA-crystallin: The pathomechanism underlying congenital cataract-causing mutations R54L, R54P and R54C.

scientific article

The interaction of beta-lactoglobulin with ciprofloxacin and kanamycin; a spectroscopic and molecular modeling approach.

scientific article published on 26 August 2016

The structural alteration and aggregation propensity of glycated lens crystallins in the presence of calcium: Importance of lens calcium homeostasis in development of diabetic cataracts.

scientific article published on 9 July 2016

The structural damages of lens crystallins induced by peroxynitrite and methylglyoxal, two causative players in diabetic complications and preventive role of lens antioxidant components.

scientific article published in May 2017

The synergistic chaperoning operation in a Bi-chaperone system consisting of alpha-crystallin and beta-casein: bovine pancreatic insulin as the target protein

scientific article published on 23 July 2011

Thermal dissection of lentil seedling amine oxidase domains by differential scanning calorimetry

scientific article published on 07 July 2007

Three Pt-Pt Complexes with Donor-acceptor Feature: Anticancer Activity, DNA Binding Studies and Molecular Docking Simulation

scientific article published on 01 January 2019

List of works by Reza Yousefi

A Comparative Study of the Impact of Calcium Ion on Structure, Aggregation and Chaperone Function of Human αA-crystallin and its Cataract- Causing R12C Mutant.

A new aspect to chaperone-like activity of bovine β-casein by protein-protein interactions study.

Aggregation and fibrillation of eye lens crystallins by homocysteinylation; implication in the eye pathological disorders.

Aggregation and structural changes of α(S1)-, β- and κ-caseins induced by homocysteinylation.

An in vitro study of the role of β-boswellic acid in the microtubule assembly dynamics

Anticancer activity and DNA-binding properties of novel cationic Pt(II) complexes.

Anticancer activity assessment of two novel binuclear platinum (II) complexes.

Anticancer and DNA binding activities of platinum (IV) complexes; importance of leaving group departure rate

Aspirin-mediated acetylation induces structural alteration and aggregation of bovine pancreatic insulin

Assessment of structure, stability and aggregation of soluble lens proteins and alpha-crystallin upon non-enzymatic glycation: The pathomechanisms underlying cataract development in diabetic patients

Binding study of novel anti-diabetic pyrimidine fused heterocycles to β-lactoglobulin as a carrier protein.

Biological activity of camel milk casein following enzymatic digestion

Chaperone activities of bovine and camel beta-caseins: Importance of their surface hydrophobicity in protection against alcohol dehydrogenase aggregation.

Chaperone-like activities of different molecular forms of beta-casein. Importance of polarity of N-terminal hydrophilic domain

Chemical modifications of insulin: Finding a compromise between stability and pharmaceutical performance

Chemometric study of the aggregation of alcohol dehydrogenase and its suppression by beta-caseins: a mechanistic perspective.

Comparative study on the interaction of two binuclear Pt (II) complexes with human serum albumin: Spectroscopic and docking simulation assessments

Dual behavior of sodium dodecyl sulfate as enhancer or suppressor of insulin aggregation and chaperone-like activity of camel alphaS(1)-casein.

Effect of homocysteine thiolactone on structure and aggregation propensity of bovine pancreatic insulin

Effect of homocysteinylation on structure, chaperone activity and fibrillation propensity of lens alpha-crystallin.

Effect of salts and sodium dodecyl sulfate on chaperone activity of camel alphaS(1)-CN: insulin as the target protein.

Effect of temperature and ionic strength on structure and chaperone activity of glycated and non-glycated alpha-crystallins

Evaluation of Structure, Chaperone-Like Activity and Allergenicity of Reduced Glycated Adduct of Bovine β-casein

Evaluation of structure, chaperone-like activity and protective ability of peroxynitrite modified human α-Crystallin subunits against copper-mediated ascorbic acid oxidation.

Fibril formation of lysozyme upon interaction with sodium dodecyl sulfate at pH 9.2.

Human αB-crystallin as fusion protein and molecular chaperone increases the expression and folding efficiency of recombinant insulin

Importance of the positively charged residue at position 54 to the chaperoning function, conformational stability and amyloidogenic nature of human αA-crystallin.

Interaction of prodigiosin with HSA and β-Lg: Spectroscopic and molecular docking studies.

Potassium sorbate as an AGE activator for human serum albumin in the presence and absence of glucose

Preventive role of lens antioxidant defense mechanism against riboflavin-mediated sunlight damaging of lens crystallins.

Protective Effects of Acetylation on the Pathological Reactions of the Lens Crystallins with Homocysteine Thiolactone.

Protective effects of carnosine on dehydroascorbate-induced structural alteration and opacity of lens crystallins: important implications of carnosine pleiotropic functions to combat cataractogenesis.

Protective role of antioxidant compounds against peroxynitrite-mediated modification of R54C mutant αA-crystallin.

Pyrimidine-fused heterocycle derivatives as a novel class of inhibitors for α-glucosidase

Structural analysis and aggregation propensity of reduced and nonreduced glycated insulin adducts.

Structural and functional alteration of human αA-crystallin after exposure to full spectrum solar radiation and preventive role of lens antioxidants

Structural changes and aggregation process of Cu/containing amine oxidase in the presence of 2,2,2'-trifluoroethanol.

Structure, Chaperone Activity, and Aggregation of Wild-Type and R12C Mutant αB-Crystallins in the Presence of Thermal Stress and Calcium Ion - Implications for Role of Calcium in Cataract Pathogenesis.

Structure, chaperone-like activity and allergenicity profile of bovine caseins upon peroxynitrite modification: New evidences underlying mastitis pathomechanisms

Studies to reveal the nature of interactions between catalase and curcumin using computational methods and optical techniques.

Synthesis and Antioxidant Activity Evaluation of Some Novel Aminocarbonitrile Derivatives Incorporating Carbohydrate Moieties

Synthesis and characterization of some new Schiff base complexes of group 13 elements, ab initio studies, cytotoxicity and reaction with hydrogen peroxide.

Synthesis of novel poly-hydroxyl functionalized acridine derivatives as inhibitors of α-Glucosidase and α-Amylase

The anticancer activity and HSA binding properties of the structurally related platinum (II) complexes.

The congenital cataract-causing mutations P20R and A171T are associated with important changes in the amyloidogenic feature, structure and chaperone-like activity of human αB-crystallin

The enhancement effect of beta-boswellic acid on hippocampal neurites outgrowth and branching (an in vitro study).

The enhancing effect of homocysteine thiolactone on insulin fibrillation and cytotoxicity of insulin fibril.

The impact of Hydrogen peroxide on structure, stability and functional properties of Human R12C mutant αA-crystallin: The imperative insights into pathomechanism of the associated congenital cataract incidence

The impact of calcium ion on structure and aggregation propensity of peroxynitrite-modified lens crystallins: new insights into the pathogenesis of cataract disorders

The impact of different mutations at Arg54 on structure, chaperone-like activity and oligomerization state of human αA-crystallin: The pathomechanism underlying congenital cataract-causing mutations R54L, R54P and R54C.

The interaction of beta-lactoglobulin with ciprofloxacin and kanamycin; a spectroscopic and molecular modeling approach.

The structural alteration and aggregation propensity of glycated lens crystallins in the presence of calcium: Importance of lens calcium homeostasis in development of diabetic cataracts.

The structural damages of lens crystallins induced by peroxynitrite and methylglyoxal, two causative players in diabetic complications and preventive role of lens antioxidant components.

The synergistic chaperoning operation in a Bi-chaperone system consisting of alpha-crystallin and beta-casein: bovine pancreatic insulin as the target protein

Thermal dissection of lentil seedling amine oxidase domains by differential scanning calorimetry

Three Pt-Pt Complexes with Donor-acceptor Feature: Anticancer Activity, DNA Binding Studies and Molecular Docking Simulation