List of works - Paul Mischel

Altered cellular metabolism in gliomas - an emerging landscape of actionable co-dependency targets

scientific article published on 05 December 2019

AmpliconReconstructor integrates NGS and optical mapping to resolve the complex structures of focal amplifications

scientific article published on 01 September 2020

Antitumor activity of rapamycin in a Phase I trial for patients with recurrent PTEN-deficient glioblastoma

scientific article

Author Correction: Longitudinal assessment of tumor development using cancer avatars derived from genetically engineered pluripotent stem cells

scientific article published on 20 April 2020

Combined analysis of O6-methylguanine-DNA methyltransferase protein expression and promoter methylation provides optimized prognostication of glioblastoma outcome

scientific article published on 17 January 2013

Extrachromosomal DNA in HPV-Mediated Oropharyngeal Cancer Drives Diverse Oncogene Transcription

scientific article published on 21 September 2021

Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers

scientific article published on 17 August 2020

Extrachromosomal oncogene amplification in tumour pathogenesis and evolution

scientific article published on 01 May 2019

Form follows function in cancer genomes

scientific article published in 2022

Gene expression analysis of glioblastomas identifies the major molecular basis for the prognostic benefit of younger age

scientific article

Genomic landscape of meningiomas.

scientific article

Graded functional diffusion map-defined characteristics of apparent diffusion coefficients predict overall survival in recurrent glioblastoma treated with bevacizumab

scientific article

IMP dehydrogenase-2 drives aberrant nucleolar activity and promotes tumorigenesis in glioblastoma

scientific article published on 01 August 2019

Identification of retinol binding protein 1 promoter hypermethylation in isocitrate dehydrogenase 1 and 2 mutant gliomas.

scientific article

Longitudinal assessment of tumor development using cancer avatars derived from genetically engineered pluripotent stem cells

scientific article published on 28 January 2020

Loss of polycomb repressive complex 1 activity and chromosomal instability drive uveal melanoma progression

scientific article published on 13 September 2021

Lyophilized brain tumor specimens can be used for histologic, nucleic acid, and protein analyses after 1 year of room temperature storage.

scientific article published on 03 May 2013

Phase II study of bevacizumab plus temozolomide during and after radiation therapy for patients with newly diagnosed glioblastoma multiforme

scientific article

Quantification of edema reduction using differential quantitative T2 (DQT2) relaxometry mapping in recurrent glioblastoma treated with bevacizumab

scientific article published on 25 June 2011

Quantitative volumetric analysis of conventional MRI response in recurrent glioblastoma treated with bevacizumab

scientific article published on 15 February 2011

Recurrent glioblastoma multiforme: ADC histogram analysis predicts response to bevacizumab treatment

scientific article

Relationship between gene expression and enhancement in glioblastoma multiforme: exploratory DNA microarray analysis

scientific article

Relationship between survival and edema in malignant gliomas: role of vascular endothelial growth factor and neuronal pentraxin 2.

scientific article published in May 2007

Somatic mutations of the Parkinson's disease-associated gene PARK2 in glioblastoma and other human malignancies

scientific article published on 29 November 2009

Stem cell associated gene expression in glioblastoma multiforme: relationship to survival and the subventricular zone

scientific article

Targeting pyrimidine synthesis accentuates molecular therapy response in glioblastoma stem cells

scientific article published on 01 August 2019

The tyrosine phosphatase PTPRD is a tumor suppressor that is frequently inactivated and mutated in glioblastoma and other human cancers

scientific journal article

Tumor-suppressive miR148a is silenced by CpG island hypermethylation in IDH1-mutant gliomas.

scientific article

Update and developments in the treatment of glioblastoma multiforme &ndash; focus on bevacizumab ⬇️

scientific article published on 09 June 2010

ecDNA hubs drive cooperative intermolecular oncogene expression

scientific article published on 24 November 2021

List of works by Paul Mischel

Altered cellular metabolism in gliomas - an emerging landscape of actionable co-dependency targets

AmpliconReconstructor integrates NGS and optical mapping to resolve the complex structures of focal amplifications

Antitumor activity of rapamycin in a Phase I trial for patients with recurrent PTEN-deficient glioblastoma

Author Correction: Longitudinal assessment of tumor development using cancer avatars derived from genetically engineered pluripotent stem cells

Combined analysis of O6-methylguanine-DNA methyltransferase protein expression and promoter methylation provides optimized prognostication of glioblastoma outcome

Extrachromosomal DNA in HPV-Mediated Oropharyngeal Cancer Drives Diverse Oncogene Transcription

Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers

Extrachromosomal oncogene amplification in tumour pathogenesis and evolution

Form follows function in cancer genomes

Gene expression analysis of glioblastomas identifies the major molecular basis for the prognostic benefit of younger age

Genomic landscape of meningiomas.

Graded functional diffusion map-defined characteristics of apparent diffusion coefficients predict overall survival in recurrent glioblastoma treated with bevacizumab

IMP dehydrogenase-2 drives aberrant nucleolar activity and promotes tumorigenesis in glioblastoma

Identification of retinol binding protein 1 promoter hypermethylation in isocitrate dehydrogenase 1 and 2 mutant gliomas.

Longitudinal assessment of tumor development using cancer avatars derived from genetically engineered pluripotent stem cells

Loss of polycomb repressive complex 1 activity and chromosomal instability drive uveal melanoma progression

Lyophilized brain tumor specimens can be used for histologic, nucleic acid, and protein analyses after 1 year of room temperature storage.

Phase II study of bevacizumab plus temozolomide during and after radiation therapy for patients with newly diagnosed glioblastoma multiforme

Quantification of edema reduction using differential quantitative T2 (DQT2) relaxometry mapping in recurrent glioblastoma treated with bevacizumab

Quantitative volumetric analysis of conventional MRI response in recurrent glioblastoma treated with bevacizumab

Recurrent glioblastoma multiforme: ADC histogram analysis predicts response to bevacizumab treatment

Relationship between gene expression and enhancement in glioblastoma multiforme: exploratory DNA microarray analysis

Relationship between survival and edema in malignant gliomas: role of vascular endothelial growth factor and neuronal pentraxin 2.

Somatic mutations of the Parkinson's disease-associated gene PARK2 in glioblastoma and other human malignancies

Stem cell associated gene expression in glioblastoma multiforme: relationship to survival and the subventricular zone

Targeting pyrimidine synthesis accentuates molecular therapy response in glioblastoma stem cells

The tyrosine phosphatase PTPRD is a tumor suppressor that is frequently inactivated and mutated in glioblastoma and other human cancers

Tumor-suppressive miR148a is silenced by CpG island hypermethylation in IDH1-mutant gliomas.

Update and developments in the treatment of glioblastoma multiforme &amp;ndash; focus on bevacizumab ⬇️

ecDNA hubs drive cooperative intermolecular oncogene expression

Update and developments in the treatment of glioblastoma multiforme – focus on bevacizumab ⬇️