Search filters

List of works by Gaston Habets

BRD4 profiling identifies critical Chronic Lymphocytic Leukemia oncogenic circuits and reveals sensitivity to PLX51107, a novel structurally distinct BET inhibitor

scientific article published on 31 January 2018

Characterizing and Overriding the Structural Mechanism of the Quizartinib-Resistant FLT3 "Gatekeeper" F691L Mutation with PLX3397

scientific article published on 6 April 2015

Clinical efficacy of a RAF inhibitor needs broad target blockade in BRAF-mutant melanoma

scientific article

Design and pharmacology of a highly specific dual FMS and KIT kinase inhibitor ⬇️

scientific article published on March 14, 2013

Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity

scientific article

Interrogating the kinome ⬇️

scientific article published on November 8, 2011

Late viral RNA export, rather than p53 inactivation, determines ONYX-015 tumor selectivity

scientific article published in December 2004

RAF inhibitors that evade paradoxical MAPK pathway activation

scientific article

RAS mutations in cutaneous squamous-cell carcinomas in patients treated with BRAF inhibitors

scientific article published on January 2012

Scaffold-based discovery of indeglitazar, a PPAR pan-active anti-diabetic agent

scientific article

Structure-Guided Blockade of CSF1R Kinase in Tenosynovial Giant-Cell Tumor

scientific article

Targeting cells of the myeloid lineage attenuates pain and disease progression in a prostate model of bone cancer

scientific article

Paulina is supported by:

About Paulina

Help