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List of works by Hiroyuki Miyoshi

A Chemosensitivity Study of Colorectal Cancer Using Xenografts of Patient-Derived Tumor-Initiating Cells

scientific article published on 03 July 2018

A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

scientific article (publication date: 13 November 2008)

A novel strategy to increase the proliferative potential of adult human β-cells while maintaining their differentiated phenotype.

scientific article

A targeted mutation of Nkd1 impairs mouse spermatogenesis.

scientific article

Accelerated onsets of gastric hamartomas and hepatic adenomas/carcinomas in Lkb1+/-p53-/- compound mutant mice

scientific article published on 01 March 2006

Accurate diagnosis of mismatch repair deficiency in colorectal cancer using high-quality DNA samples from cultured stem cells

An improved method for culturing patient-derived colorectal cancer spheroids.

scientific article published on 24 April 2018

Arid1a is essential for intestinal stem cells through Sox9 regulation

scientific article published on 11 January 2019

Berberine and its more biologically available derivative, dihydroberberine, inhibit mitochondrial respiratory complex I: a mechanism for the action of berberine to activate AMP-activated protein kinase and improve insulin action

scientific article

Butyrate and bioactive proteolytic form of Wnt-5a regulate colonic epithelial proliferation and spatial development.

scientific article published on 26 August 2016

Chemosensitivity of Patient-Derived Cancer Stem Cells Identifies Colorectal Cancer Patients with Potential Benefit from FGFR Inhibitor Therapy

scientific article published on 22 July 2020

Counteracting stem cell expansion during wound repair: distinct roles of non-canonical Wnt and TGF-β.

scientific article published on 16 January 2013

Development of a primary mouse intestinal epithelial cell monolayer culture system to evaluate factors that modulate IgA transcytosis

scientific article

Development of an enhanced human gastrointestinal epithelial culture system to facilitate patient-based assays.

scientific article

Distinct Roles of HES1 in Normal Stem Cells and Tumor Stem-like Cells of the Intestine.

scientific article published on 23 May 2017

Efficient colonic mucosal wound repair requires Trem2 signaling

scholarly article

Expression of metastasis suppressor gene AES driven by a Yin Yang (YY) element in a CpG island promoter and transcription factor YY2.

scientific article published on 25 August 2016

Hepatocellular carcinoma development induced by conditional beta-catenin activation in Lkb1+/- mice.

scientific article

Identification of Aging-Associated Gene Expression Signatures That Precede Intestinal Tumorigenesis.

scientific article

Igf2bp1 is required for full induction of Ptgs2 mRNA in colonic mesenchymal stem cells in mice.

scientific article published on 27 March 2012

In vitro expansion and genetic modification of gastrointestinal stem cells in spheroid culture.

scientific article

Inhibition of Cyclooxygenase-2 Prevents Chronic and Recurrent Cystitis.

scientific article published on 24 October 2014

LKB1 suppresses p21-activated kinase-1 (PAK1) by phosphorylation of Thr109 in the p21-binding domain

scientific article

Lineage tracing and targeting of IL17RB+ tuft cell-like human colorectal cancer stem cells

scientific article published on 10 June 2019

MicroRNA-9-5p-CDX2 Axis: A Useful Prognostic Biomarker for Patients with Stage II/III Colorectal Cancer

scientific article published on 27 November 2019

Nonmyelinating Schwann cells maintain hematopoietic stem cell hibernation in the bone marrow niche

scientific article published on 01 November 2011

Prostaglandin E2 promotes intestinal repair through an adaptive cellular response of the epithelium

scientific article published on 24 October 2016

SMAD4-deficient intestinal tumors recruit CCR1+ myeloid cells that promote invasion

scientific article published on 18 March 2007

Suppression of tubulin polymerization by the LKB1-microtubule-associated protein/microtubule affinity-regulating kinase signaling

scientific article published on 15 June 2007

Targeted disruption of G protein-coupled bile acid receptor 1 (Gpbar1/M-Bar) in mice.

scientific article published in October 2006

The role of stromal stem cells in tissue regeneration and wound repair.

scientific article

The young and the Wnt-less: transplantable fetal intestinal spheroids without Wnts.

scientific article published on December 2013

Transgenic mice that accept Luciferase- or GFP-expressing syngeneic tumor cells at high efficiencies

scientific article published on 11 May 2018

Type I interferons link viral infection to enhanced epithelial turnover and repair.

scientific article

Wnt-expressing cells in the intestines: guides for tissue remodeling

scientific article published on 8 November 2016

Wnt5a Potentiates TGF-β Signaling to Promote Colonic Crypt Regeneration After Tissue Injury ⬇️

scientific article published on September 6, 2012

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