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List of works by Gibran Hemani

A Phenome-Wide Mendelian Randomization Study of Pancreatic Cancer Using Summary Genetic Data

scientific article published on 17 July 2019

A transcriptome-wide Mendelian randomization study to uncover tissue-dependent regulatory mechanisms across the human phenome

A transcriptome-wide Mendelian randomization study to uncover tissue-dependent regulatory mechanisms across the human phenome

scientific article published on 10 January 2020

An atlas of polygenic risk score associations to highlight putative causal relationships across the human phenome

An evolutionary perspective on epistasis and the missing heritability

scientific article

An integrative approach to detect epigenetic mechanisms that putatively mediate the influence of lifestyle exposures on disease susceptibility

scientific article published on 01 June 2019

Apparent latent structure within the UK Biobank sample has implications for epidemiological analysis

scientific article published in Nature Communications

Applying Mendelian randomization to appraise causality in relationships between nutrition and cancer

scientific article published in May 2022

Appraising the causal relevance of DNA methylation for risk of lung cancer

Appraising the causal relevance of DNA methylation for risk of lung cancer

scientific article published on 01 October 2019

Association Between Telomere Length and Risk of Cancer and Non-Neoplastic Diseases: A Mendelian Randomization Study ⬇️

scientific article published on 23 February 2017

Association of Schizophrenia Risk With Disordered Niacin Metabolism in an Indian Genome-wide Association Study

scientific article published on 03 July 2019

Associations of Mitochondrial and Nuclear Mitochondrial Variants and Genes with Seven Metabolic Traits

article

Author Correction: Bayesian reassessment of the epigenetic architecture of complex traits

scientific article published on 09 October 2020

Avoiding dynastic, assortative mating, and population stratification biases in Mendelian randomization through within-family analyses

scientific article published on 14 July 2020

Bayesian reassessment of the epigenetic architecture of complex traits

scientific article published on 08 June 2020

C9orf72 hexanucleotide repeat expansions in Chinese sporadic amyotrophic lateral sclerosis.

scientific article

Calculating Power to Detect Maternal and Offspring Genetic Effects in Genetic Association Studies

scientific article published on 02 January 2019

Causal inference for heritable phenotypic risk factors using heterogeneous genetic instruments

scientific article published in 2021

Challenges and novel approaches for investigating molecular mediation.

scientific article published on 20 July 2016

Characterisation of genome-wide association epistasis signals for serum uric acid in human population isolates

scientific article

Collapsed methylation quantitative trait loci analysis for low frequency and rare variants

scientific article published on 24 August 2016

Collider bias from selecting disease samples distorts causal inferences

scientific article published in 2022

Collider bias undermines our understanding of COVID-19 disease risk and severity

scientific article published on 12 November 2020

Comment on the Relationship Between Common Variant Schizophrenia Liability and Number of Offspring in the UK Biobank

scientific article published on 01 July 2019

Congruence of additive and non-additive effects on gene expression estimated from pedigree and SNP data

scientific article

Contacts and behaviours of university students during the COVID-19 pandemic at the start of the 2020/2021 academic year

scientific article published on 3 June 2021

Contribution of genetic variation to transgenerational inheritance of DNA methylation

scientific article

Correction to: Is population structure in the genetic biobank era irrelevant, a challenge, or an opportunity?

scientific article published on 01 January 2020

Correction: Orienting the causal relationship between imprecisely measured traits using GWAS summary data

scientific article published on 29 December 2017

DNA methylome-wide association study of genetic risk for depression implicates antigen processing and immune responses

scientific article published on 31 March 2022

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

Directional dominance on stature and cognition in diverse human populations

scientific article published in July 2015

Endometriosis risk alleles at 1p36.12 act through inverse regulation of CDC42 and LINC00339.

scientific article

EpiGPU: exhaustive pairwise epistasis scans parallelized on consumer level graphics cards

scientific article

Estimating the causal influence of body mass index on risk of Parkinson disease: A Mendelian randomisation study

scientific article published on 13 June 2017

Evaluating the potential role of pleiotropy in Mendelian randomization studies

scientific article published in August 2018

Evidence for DNA methylation mediating genetic liability to non-syndromic cleft lip/palate.

scientific article published on 14 January 2019

Evidence for causal effects of lifetime smoking on risk for depression and schizophrenia: a Mendelian randomisation study

scientific article published on 06 November 2019

Exploiting horizontal pleiotropy to search for causal pathways within a Mendelian randomization framework

scientific article published on 21 February 2020

Genetic Association of Albuminuria with Cardiometabolic Disease and Blood Pressure

article published in 2018

Genetic correlations reveal the shared genetic architecture of transcription in human peripheral blood

scientific article published on 7 September 2017

Genetic evidence for assortative mating on alcohol consumption in the UK Biobank

scientific article published on 19 November 2019

Genetic variance estimation with imputed variants finds negligible missing heritability for human height and body mass index

scientific article

Genome-Wide Meta-Analysis of Cotinine Levels in Cigarette Smokers Identifies Locus at 4q13.2.

scientific article published on February 2016

Genome-wide analysis of mitral valve disease in Cavalier King Charles Spaniels

article

Genome-wide association meta-analysis of individuals of European ancestry identifies new loci explaining a substantial fraction of hair color variation and heritability

scientific article published on 16 April 2018

Genome-wide association studies identify 137 genetic loci for DNA methylation biomarkers of aging

scientific article

Genome-wide association study identifies nine novel loci for 2D:4D finger ratio, a putative retrospective biomarker of testosterone exposure in utero

scientific article published on 12 April 2018

Genome-wide association study of blood lead shows multiple associations near ALAD

scientific article published in July 2015

Genome-wide associations for birth weight and correlations with adult disease

scientific article

Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions

scientific article published on 04 February 2019

Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions.: Supplementary Information

Genome-wide survey of parent-of-origin effects on DNA methylation identifies candidate imprinted loci in humans

scientific article published on 15 August 2018

Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation

scientific article

Hemani et al. reply

scientific article published on October 2014

High COVID-19 transmission potential associated with re-opening universities can be mitigated with layered interventions

scientific article published on 17 August 2021

Identical twins carry a persistent epigenetic signature of early genome programming

scientific article

Identification of loci where DNA methylation potentially mediates genetic risk of type 1 diabetes

scientific article published on 29 June 2018

Identifying drug targets for neurological and psychiatric disease via genetics and the brain transcriptome

scientific article published on 08 January 2021

Improved heritability estimation from genome-wide SNPs

scientific article

Inference of the genetic architecture underlying BMI and height with the use of 20,240 sibling pairs

scientific article published on 31 October 2013

Integrative analysis of gene expression, DNA methylation, physiological traits, and genetic variation in human skeletal muscle

scientific article published on 10 May 2019

Investigating the causal relationship between neuroticism and depression via Mendelian randomization

scientific article published on 17 February 2019

Investigating the shared genetics of non-syndromic cleft lip/palate and facial morphology

scientific article published in August 2018

Invited Commentary: Detecting Individual and Global Horizontal Pleiotropy in Mendelian Randomization—A Job for the Humble Heterogeneity Statistic?

scientific article published on 5 September 2018

Is disrupted sleep a risk factor for Alzheimer's disease? Evidence from a two-sample Mendelian randomization analysis

scientific article published on 05 November 2020

Is population structure in the genetic biobank era irrelevant, a challenge, or an opportunity?

scientific article published on 27 April 2019

LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis.

scientific article

Limits of lockdown: characterising essential contacts during strict physical distancing

scientific article published on 14 May 2021

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors

scientific article published on 01 May 2019

Meffil: efficient normalization and analysis of very large DNA methylation datasets

scientific article published on 21 June 2018

Mendelian Randomization Analysis Identifies CpG Sites as Putative Mediators for Genetic Influences on Cardiovascular Disease Risk.

scientific article published in October 2017

Mendelian randomization evaluation of causal effects of fibrinogen on incident coronary heart disease

scientific article published on 10 May 2019

Mendelian randomization: genetic anchors for causal inference in epidemiological studies

scientific article published on 15 September 2014

Modelling pooling strategies for SARS-CoV-2 testing in a university setting

scientific article published on 30 March 2021

Orienting the causal relationship between imprecisely measured traits using GWAS summary data

scientific article published on 17 November 2017

Partitioning Phenotypic Variance Due to Parent-of-Origin Effects Using Genomic Relatedness Matrices

scientific article published on 2 November 2017

Pathways between early-life adversity and adolescent self-harm: the mediating role of inflammation in the Avon Longitudinal Study of Parents and Children

scientific article published on 04 September 2019

PhenoSpD: an integrated toolkit for phenotypic correlation estimation and multiple testing correction using GWAS summary statistics

scientific article published in August 2018

Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases

scientific article published on 07 September 2020

Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis

scientific article published on 15 January 2016

Population genetic differentiation of height and body mass index across Europe

scientific article

Population phenomena inflate genetic associations of complex social traits

scientific article published on 15 April 2020

Prenatal alcohol exposure and facial morphology in a UK cohort

scientific article published on 05 February 2019

Prenatal and early life influences on epigenetic age in children: a study of mother-offspring pairs from two cohort studies

scientific article published on 5 November 2015

Publisher Correction: Genome-wide association meta-analysis of individuals of European ancestry identifies new loci explaining a substantial fraction of hair color variation and heritability

scientific article published on 01 July 2019

RETRACTED ARTICLE: Detection and replication of epistasis influencing transcription in humans

retracted scholarly article

Recent Developments in Mendelian Randomization Studies

scientific article published on 22 November 2017

Response to Lee et al.: SNP-based heritability analysis with dense data

scientific article published on December 2013

Schizophrenia liability shares common molecular genetic risk factors with sleep duration and nightmares in childhood

Schizophrenia liability shares common molecular genetic risk factors with sleep duration and nightmares in childhood

scientific article published on 20 August 2019

Schizophrenia risk and reproductive success: a Mendelian randomization study

scientific article published on 06 March 2019

Shared genetic control of expression and methylation in peripheral blood

scientific article

Statistical power to detect genetic (co)variance of complex traits using SNP data in unrelated samples.

scientific article

Systematic Mendelian randomization framework elucidates hundreds of CpG sites which may mediate the influence of genetic variants on disease

scientific article published on 15 September 2018

Systematic identification of genetic influences on methylation across the human life course

scientific article published on 31 March 2016

The EWAS Catalog: a database of epigenome-wide association studies

scientific article published in 2022

The MR-Base platform supports systematic causal inference across the human phenome.

scientific article published on 30 May 2018

The Parkinson's Disease Mendelian Randomization Research Portal

scientific article published on 28 October 2019

The association between genetically elevated polyunsaturated fatty acids and risk of cancer

scientific article published in May 2023

The association between lower educational attainment and depression owing to shared genetic effects? Results in ~25,000 subjects

scientific article published in June 2015

The role of common genetic variation in educational attainment and income: evidence from the National Child Development Study

scientific article published on 12 November 2015

The role of glycaemic and lipid risk factors in mediating the effect of BMI on coronary heart disease: a two-step, two-sample Mendelian randomisation study.

scientific article published on 9 September 2017

The variant call format provides efficient and robust storage of GWAS summary statistics

scientific article published on 13 January 2021

Trans-ethnic kidney function association study reveals putative causal genes and effects on kidney-specific disease aetiologies

scientific article published in Nature Communications

Two-sample Mendelian randomization: avoiding the downsides of a powerful, widely applicable but potentially fallible technique

scientific article published on 15 March 2017

Understanding the consequences of education inequality on cardiovascular disease: mendelian randomisation study.

scientific article

Unraveling the polygenic architecture of complex traits using blood eQTL meta-analysis

scholarly article published 19 October 2018

Using Genetic Instruments to Estimate Interactions in Mendelian Randomization Studies

scientific article published on 01 November 2019

Using the MR-Base platform to investigate risk factors and drug targets for thousands of phenotypes

scientific article published on 07 November 2019

Using the MR-Base platform to investigate risk factors and drug targets for thousands of phenotypes

scientific article published in 2019

What explains the effect of education on cardiovascular disease? Applying Mendelian randomization to identify the consequences of education inequality:

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