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List of works by Ari Zimran

13,845 home therapy infusions with velaglucerase alfa exemplify safety of velaglucerase alfa and increased compliance to every-other-week intravenous enzyme replacement therapy for Gaucher disease

scientific article published on 21 September 2015

A Multicenter, Double-Blind, Randomized Safety and Efficacy Study of Two Dose Levels of Taliglucerase Alfa in Pediatric Patients with Gaucher Disease. ⬇️

scholarly article

A Phase 3, multicenter, open-label, switchover trial to assess the safety and efficacy of taliglucerase alfa, a plant cell-expressed recombinant human glucocerebrosidase, in adult and pediatric patients with Gaucher disease previously treated with i

scientific article published on 18 June 2014

A comprehensive assessment of renal function in patients with Gaucher disease

scientific article published in November 2005

A plant-derived recombinant human glucocerebrosidase enzyme--a preclinical and phase I investigation

scientific article published in 2009

A validated disease severity scoring system for adults with type 1 Gaucher disease

scientific article published on 01 January 2010

Achievement of therapeutic goals with low-dose imiglucerase in Gaucher disease: a single-center experience

scientific article

Bone mineral density in gravida: effect of pregnancies and breast-feeding in women of differing ages and parity.

scientific article

Booster-effect with velaglucerase alfa in patients with Gaucher disease switched from long-term imiglucerase therapy: Early Access Program results from Jerusalem ⬇️

scientific article published on 01 November 2011

Carrier screening for Gaucher disease: lessons for low-penetrance, treatable diseases

scientific article

Characteristics of 26 patients with type 3 Gaucher disease: A descriptive analysis from the Gaucher Outcome Survey

scientific article published on 27 December 2017

Characteristics of type I Gaucher disease associated with persistent thrombocytopenia after treatment with imiglucerase for 4-5 years

scientific article

Children with type 1 Gaucher disease: Changing profiles in the 21st century

scientific article

Clinical course and prognosis in patients with Gaucher disease and parkinsonism

scientific article published on 4 March 2016

Comparison of Bone Mineral Density by Dual-Energy X-Ray Absorptiometry and Bone Strength by Speed-of-Sound Ultrasonography in Adults With Gaucher Disease

scientific article published on 15 January 2016

Comparison of Parkinson risk in Ashkenazi Jewish patients with Gaucher disease and GBA heterozygotes

scientific article

Demographics and patient characteristics of 1209 patients with Gaucher disease: Descriptive analysis from the Gaucher Outcome Survey (GOS).

scientific article published in November 2017

Dental profile of patients with Gaucher disease

scientific article

Disease severity in sibling pairs with type 1 Gaucher disease

scientific article published on 05 January 2010

Dose-response relationships for enzyme replacement therapy with imiglucerase/alglucerase in patients with Gaucher disease type 1.

scientific article published on February 2009

Early access experience with VPRIV(®): recommendations for 'core data' collection.

scientific article published on 13 December 2010

Effect of enzyme replacement therapy on gammopathies in Gaucher disease

scientific article published on 01 January 2004

Effect of enzyme replacement therapy with imiglucerase on BMD in type 1 Gaucher disease

scientific article published on 01 January 2007

Effectiveness of enzyme replacement therapy in 1028 patients with type 1 Gaucher disease after 2 to 5 years of treatment: a report from the Gaucher Registry

scientific article

Enzyme replacement therapy with taliglucerase alfa: 36-month safety and efficacy results in adult patients with Gaucher disease previously treated with imiglucerase

scientific article published on 22 April 2016

Enzyme replacement therapy with velaglucerase alfa in Gaucher disease: Results from a randomized, double‐blind, multinational, Phase 3 study ⬇️

scientific article published on February 6, 2013

Exploring the patient journey to diagnosis of Gaucher disease from the perspective of 212 patients with Gaucher disease and 16 Gaucher expert physicians

scientific article published on 04 August 2017

Force majeure: therapeutic measures in response to restricted supply of imiglucerase (Cerezyme) for patients with Gaucher disease

scientific article published on 4 October 2009

Gaucher disease and cancer incidence: a study from the Gaucher Registry

scientific article published on 17 February 2005

Gaucher disease and the clinical experience with substrate reduction therapy

scientific article

Gaucher disease in Arab patients at an Israeli referral clinic

scientific article published on 01 August 2008

Gaucher disease type 1: revised recommendations on evaluations and monitoring for adult patients

scientific article published on 01 October 2004

Gaucher disease: pediatric concerns

scientific article

Gaucher disease: spectrum of sonographic findings in the liver

scientific article published in May 2010

Glucocerebroside: an evolutionary advantage for patients with Gaucher disease and a new immunomodulatory agent

scientific article published on 16 June 2009

Glucosylsphingosine (lyso-Gb1) as a Biomarker for Monitoring Treated and Untreated Children with Gaucher Disease

scientific article published on 21 June 2019

Glucosylsphingosine is a highly sensitive and specific biomarker for primary diagnostic and follow-up monitoring in Gaucher disease in a non-Jewish, Caucasian cohort of Gaucher disease patients

scientific article

Glucosylsphingosine is a reliable response biomarker in Gaucher disease

scientific article published on 15 March 2018

Growth and final height of children with Gaucher disease: A 15-year follow-up at an Israeli Gaucher center

scientific article

Guidelines for the restart of imiglucerase in patients with Gaucher disease: recommendations from the European Working Group on Gaucher disease

scientific article published on 01 March 2010

Hepatocellular carcinoma in Gaucher disease: an international case series.

scientific article published on 8 February 2018

Iliopsoas haematoma in Gaucher disease

scientific article

Iliopsoas hematoma in a young patient with type I Gaucher disease

scientific article published on 01 September 2003

Impaired platelet function and peripartum bleeding in women with Gaucher disease

scientific article

Improvement in bone marrow infiltration in patients with type I Gaucher disease treated with taliglucerase alfa

scientific article published on 31 July 2018

Incidence of malignancies among patients with type I Gaucher disease from a single referral clinic

scientific article published in May 2005

Increased prevalence of cholelithiasis in Gaucher disease: association with splenectomy but not with gilbert syndrome

scientific article published in August 2004

Long-term efficacy and safety results of taliglucerase alfa through 5years in adult treatment-naïve patients with Gaucher disease

scientific article

Long-term efficacy and safety results of taliglucerase alfa up to 36 months in adult treatment-naïve patients with Gaucher disease

scientific article published on 19 March 2016

Long-term safety and efficacy of taliglucerase alfa in pediatric Gaucher disease patients who were treatment-naïve or previously treated with imiglucerase

scientific article published on 20 October 2016

Macular Ganglion Cell Complex and Peripapillary Retinal Nerve Fiber Layer Thinning in Patients with Type-1 Gaucher Disease

scientific article published on 24 September 2020

Management of Gaucher disease: enzyme replacement therapy

scientific article

Menetrier's disease presenting as an acute protein-losing gastroenteropathy in a 27-year-old man with Gaucher disease

scientific article published in June 2005

Miglustat therapy in type 1 Gaucher disease: clinical and safety outcomes in a multicenter retrospective cohort study.

scientific article published on 14 May 2013

Multiple hypoechoic hepatic lesions in a patient with Gaucher disease

scientific article

N-brain natriuretic peptide: correlation with tricuspid insufficiency in Gaucher disease

scientific article published on 01 January 2004

National health budgets for expensive orphan drugs: Gaucher disease in Israel as a model

scientific article published on 07 July 2006

New directions in the treatment of Gaucher disease

scientific article published on March 2004

Novel oral treatment of Gaucher's disease with N-butyldeoxynojirimycin (OGT 918) to decrease substrate biosynthesis

scientific article

Open-label, expanded access study of taliglucerase alfa in patients with Gaucher disease requiring enzyme replacement therapy

scientific article published on 24 February 2020

Oral maintenance clinical trial with miglustat for type I Gaucher disease: switch from or combination with intravenous enzyme replacement.

scientific article

Organ volume by computed tomography correlates with longitudinal axis on ultrasound in patients with Gaucher disease

scientific article published in December 2011

Orthopedic considerations in Gaucher disease since the advent of enzyme replacement therapy

scientific article

Osteonecrosis in a patient with Gaucher's disease treated with enzyme replacement

scientific article published on 01 August 2003

Outcome of pregnancies in women receiving velaglucerase alfa for Gaucher disease

scientific article

Outcome of ten years' echocardiographic follow-up in children with Gaucher disease

scientific article published on 29 August 2006

Outcomes after 8 years of eliglustat therapy for Gaucher disease type 1: Final results from the Phase 2 trial

scholarly article by Elena Lukina et al published January 2019 in American Journal of Hematology

Phenotypic heterogeneity in patients with Gaucher disease and the N370S/V394L genotype

scientific article published in January 2005

Pivotal trial with plant cell-expressed recombinant glucocerebrosidase, taliglucerase alfa, a novel enzyme replacement therapy for Gaucher disease

scientific article

Plasma chitotriosidase activity versus CCL18 level for assessing type I Gaucher disease severity: protocol for a systematic review with meta-analysis of individual participant data.

scientific article

Platelet counts and interleukin-6 (IL-6) promoter polymorphism in patients with Gaucher disease

scientific article

Poor results of drilling in early stages of juxta-articular osteonecrosis in 12 joints affected by Gaucher disease.

scientific article

Pregnancies in Gaucher disease: a 5-year study

scientific article published on February 2004

Presenting signs and patient co-variables in Gaucher disease: outcome of the Gaucher Early Diagnosis Consensus (GED-C) Delphi initiative

scientific article published on 01 May 2019

Prevalence of type 1 Gaucher disease in the United States

scientific article published on 01 February 2008

Prevention of lysosomal storage diseases and derivation of mutant stem cell lines by preimplantation genetic diagnosis.

scientific article published on 26 December 2012

Proof-of-principle rapid noninvasive prenatal diagnosis of autosomal recessive founder mutations

scientific article

Proteinase-activated receptor (PAR1) polymorphic variant correlates with thrombocytopenia in Gaucher disease

scientific article

Pyrimethamine increases β-hexosaminidase A activity in patients with Late Onset Tay Sachs

scientific article

Rapid intravenous infusion of velaglucerase-alfa in adults with type 1 Gaucher disease

scientific article published on 09 August 2018

Repeat abdominal ultrasound evaluation of 100 patients with type I Gaucher disease treated with enzyme replacement therapy for up to 7 years

scientific article published on 01 January 2002

Reported outcomes of 453 pregnancies in patients with Gaucher disease: An analysis from the Gaucher outcome survey

scientific article

Review of the safety and efficacy of imiglucerase treatment of Gaucher disease

scientific article published on 15 September 2009

Safety and efficacy of two dose levels of taliglucerase alfa in pediatric patients with Gaucher disease

scientific article published on 7 November 2014

Safety and efficacy of velaglucerase alfa in Gaucher disease type 1 patients previously treated with imiglucerase.

scientific article published on 22 January 2013

Safety and efficacy results of switch from imiglucerase to velaglucerase alfa treatment in patients with type 1 Gaucher disease.

scientific article published in July 2015

Seven-year safety and efficacy with velaglucerase alfa for treatment-naïve adult patients with type 1 Gaucher disease

scientific article published on 28 May 2015

Skeletal improvement in patients with Gaucher disease type 1: a phase 2 trial of oral eliglustat

scientific article

Spectrum of abdominal sonographic findings in 103 pediatric patients with Gaucher disease

scientific article published on 07 September 2001

Substrate reduction therapy for GBA1-associated Parkinsonism: Are we betting on the wrong mouse?

scientific article published on 11 November 2019

Survey of hematological aspects of Gaucher disease

scientific article

Tc-99m sestamibi bone marrow scintigraphy in Gaucher disease

scientific article published on 01 July 2002

The 1604A (R496H) mutation in Gaucher disease: genotype/phenotype correlation

scientific article published in September 2003

The definition of neuronopathic Gaucher disease

scientific article published on 03 April 2020

The emergence of Parkinson disease among patients with Gaucher disease

scientific article published on 23 August 2014

The female Gaucher patient: the impact of enzyme replacement therapy around key reproductive events (menstruation, pregnancy and menopause).

scientific article published on 06 June 2009

The incidence of Parkinsonism in patients with type 1 Gaucher disease: data from the ICGG Gaucher Registry

scientific article

The management of pregnancy in Gaucher disease ⬇️

scientific article published on January 26, 2011

Thromboelastography as a Surrogate Marker of Perisurgical Hemostasis in Gaucher Disease

scientific article

Treatment-naïve Gaucher disease patients achieve therapeutic goals and normalization with velaglucerase alfa by 4years in phase 3 trials

scientific article

Type I Gaucher disease in children with and without enzyme therapy

scientific article published on 01 September 2002

Uncomplicated outcome after anesthesia for pediatric patients with Gaucher disease

scientific article

Uveitis in Gaucher disease

scientific article

Value of Glucosylsphingosine (Lyso-Gb1) as a Biomarker in Gaucher Disease: A Systematic Literature Review

scientific article published on 28 September 2020

Velaglucerase alfa (VPRIV) enzyme replacement therapy in patients with Gaucher disease: Long-term data from phase III clinical trials.

scientific article

Velaglucerase alfa enzyme replacement therapy compared with imiglucerase in patients with Gaucher disease ⬇️

scientific article published on February 9, 2013

Zimran A, Brill-Almon E, Chertkoff R, et al. Pivotal trial with plant cell?expressed recombinant glucocerebrosidase, taliglucerase alfa, a novel enzyme replacement therapy for Gaucher disease. Blood. 2011;118(22):.

scientific article published in May 2012

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