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List of works by Ralf Schirrmacher

(89)Zr, a radiometal nuclide with high potential for molecular imaging with PET: chemistry, applications and remaining challenges.

scientific article published on 03 June 2013

18F-labeling of peptides by means of an organosilicon-based fluoride acceptor

scientific article published on 01 September 2006

A Kinome-Wide Selective Radiolabeled TrkB/C Inhibitor for in Vitro and in Vivo Neuroimaging: Synthesis, Preclinical Evaluation, and First-in-Human

scientific article published on 11 July 2017

A Universally Applicable 68Ga-Labeling Technique for Proteins ⬇️

scientific article published on March 18, 2011

An approach to the evaluation of the activity of the DNA repair enzyme O6-methylguanine-DNA-methyl-transferase in tumor tissue in vivo: syntheses of 6-benzyloxy-9-(2-[18F]fluoroethyl)-9H-purin-2-yl-amine and 6-benzyloxy-7-(2-[18F]fluoroethyl)-7H-pur

scientific article published in March 2002

Automated production of [18F]SiTATE on a Scintomics GRP™ platform for PET/CT imaging of neuroendocrine tumors

scientific article published on 30 July 2020

Basal opioid receptor binding is associated with differences in sensory perception in healthy human subjects: a [18F]diprenorphine PET study

scientific article published on 22 August 2009

Bimodal imaging probes for combined PET and OI: recent developments and future directions for hybrid agent development

scientific article published on 16 April 2014

Current State of Radiolabeled Heterobivalent Peptidic Ligands in Tumor Imaging and Therapy

scientific article published on 30 July 2020

Design of brain imaging agents for positron emission tomography: do large bioconjugates provide an opportunity for in vivo brain imaging?

scientific article published on September 2013

Design, Synthesis, In Vitro, and Initial In Vivo Evaluation of Heterobivalent Peptidic Ligands Targeting Both NPY(Y₁)- and GRP-Receptors-An Improvement for Breast Cancer Imaging?

scholarly article by Alicia Vall-Sagarra et al published 4 July 2018 in Pharmaceuticals

Direct one-step labeling of cysteine residues on peptides with [(11)C]methyl triflate for the synthesis of PET radiopharmaceuticals

scientific article

Efficient radiosynthesis and preclinical evaluation of [18 F]FOMPyD as a positron emission tomography tracer candidate for TrkB/C receptor imaging

scientific article published on 29 January 2020

Evaluation of an automated double-synthesis module: efficiency and reliability of subsequent radiosyntheses of FHBG and FLT ⬇️

scientific article published on December 14, 2011

First-in-Human Brain Imaging of [18F]TRACK, a PET tracer for Tropomyosin Receptor Kinases

scientific article published on 29 April 2019

From Unorthodox to Established: The Current Status of (18)F-Trifluoroborate- and (18)F-SiFA-Based Radiopharmaceuticals in PET Nuclear Imaging

scientific article published on 13 November 2015

Fully automated SPE-based synthesis and purification of 2-[18F]fluoroethyl-choline for human use ⬇️

scientific article published on October 27, 2010

Gastrin-Releasing Peptide Receptor- and Prostate-Specific Membrane Antigen-Specific Ultrasmall Gold Nanoparticles for Characterization and Diagnosis of Prostate Carcinoma via Fluorescence Imaging

scientific article published on 15 March 2018

Hybrid Multimodal Imaging Synthons for Chemoselective and Efficient Biomolecule Modification with Chelator and Near-Infrared Fluorescent Cyanine Dye

scientific article published on 16 September 2020

Identification of [18F]TRACK, a Fluorine-18-Labeled Tropomyosin Receptor Kinase (Trk) Inhibitor for PET Imaging

scientific article published on 19 December 2017

Improved work-up procedure for the production of [(18)F]flumazenil and first results of its use with a high-resolution research tomograph in human stroke

scientific article published on 29 July 2009

In Vivo Evaluation of ¹⁸F-SiFAlin-Modified TATE: A Potential Challenge for ⁶⁸Ga-DOTATATE, the Clinical Gold Standard for Somatostatin Receptor Imaging with PET.

scientific article published on 14 May 2015

In vitro and initial in vivo evaluation of (68)Ga-labeled transferrin receptor (TfR) binding peptides as potential carriers for enhanced drug transport into TfR expressing cells

scientific article

Kit-like 18F-labeling of proteins: synthesis of 4-(di-tert-butyl[18F]fluorosilyl)benzenethiol (Si[18F]FA-SH) labeled rat serum albumin for blood pool imaging with PET.

scientific article

Lewis Acid-Facilitated Radiofluorination of MN3PU: A LRRK2 Radiotracer

scientific article published on 14 October 2020

Molecular imaging of cardiac CXCR4 expression in a mouse model of acute myocardial infarction using a novel 68Ga-mCXCL12 PET tracer

scientific article published on 16 July 2020

Multimerization of cRGD Peptides by Click Chemistry: Synthetic Strategies, Chemical Limitations, and Influence on Biological Properties ⬇️

scientific article published on October 18, 2010

On the Viability of Tadalafil-Based <sup>18</sup>F-Radiotracers for <i>In Vivo</i> Phosphodiesterase 5 (PDE5) PET Imaging

scientific article published on 12 August 2021

One-step 18F-labeling of peptides for positron emission tomography imaging using the SiFA methodology ⬇️

scientific article published on 04 October 2012

One-step ¹⁸F-labeling of carbohydrate-conjugated octreotate-derivatives containing a silicon-fluoride-acceptor (SiFA): in vitro and in vivo evaluation as tumor imaging agents for positron emission tomography (PET).

scientific article published on 17 November 2010

Opioid receptor PET reveals the psychobiologic correlates of reward processing

scientific article

Oxalic Acid Supported Si–18F-Radiofluorination: One-Step Radiosynthesis of N-Succinimidyl 3-(Di-tert-butyl[18F]fluorosilyl)benzoate ([18F]SiFB) for Protein Labeling ⬇️

scientific article published on January 5, 2012

Parametric mapping of binding in human brain of D2 receptor ligands of different affinities

scientific article

Positron emission tomography in the assessment of left ventricular function in healthy rats: a comparison of four imaging methods

scientific article published on 19 December 2012

Protein labeling with the labeling precursor [18F]SiFA-SH for positron emission tomography ⬇️

scientific article published on October 4, 2012

Radiolabeled heterobivalent peptidic ligands: an approach with high future potential for in vivo imaging and therapy of malignant diseases

scientific article published on 05 April 2013

Radioligands for Tropomyosin Receptor Kinase (Trk) Positron Emission Tomography Imaging

scientific article published on 03 January 2019

Radiosynthesis of [18F]SiFAlin-TATE for clinical neuroendocrine tumor positron emission tomography

scientific article published on 23 November 2020

Recent Advances in the Development and Application of Radiolabeled Kinase Inhibitors for PET Imaging

scientific article

Simple and convenient radiolabeling of proteins using a prelabeling-approach with thiol-DOTA.

scientific article published on 20 February 2009

Small Prosthetic Groups in 18F-Radiochemistry: Useful Auxiliaries for the Design of 18F-PET Tracers.

scientific article

Synthesis and in vitro and in vivo evaluation of SiFA-tagged bombesin and RGD peptides as tumor imaging probes for positron emission tomography

scientific article published on 4 April 2014

Synthesis and in vitro evaluation of (S)-2-([11C]methoxy)-4-[3-methyl-1-(2-piperidine-1-yl-phenyl)-butyl-carbamoyl]-benzoic acid ([11C]methoxy-repaglinide): a potential beta-cell imaging agent

scientific article published in October 2004

Synthesis and in vitro evaluation of biotinylated RG108: a high affinity compound for studying binding interactions with human DNA methyltransferases

scientific article published in March 2006

Synthesis and preliminary evaluation of (R,R)(S,S) 5-(2-(2-[4-(2-[(18)F]fluoroethoxy)phenyl]-1-methylethylamino)-1-hydroxyethyl)-benzene-1,3-diol ([(18)F]FEFE) for the in vivo visualisation and quantification of the beta2-adrenergic receptor status

scientific article published on 01 August 2003

Synthesis of [18F]SiFB: a prosthetic group for direct protein radiolabeling for application in positron emission tomography ⬇️

scientific article published on October 4, 2012

Synthesis of p-(di-tert-butyl[(18)F]fluorosilyl)benzaldehyde ([(18)F]SiFA-A) with high specific activity by isotopic exchange: a convenient labeling synthon for the (18)F-labeling of N-amino-oxy derivatized peptides

Synthesis, in vitro and in vivo evaluation of 18F-fluoronorimatinib as radiotracer for Imatinib-sensitive gastrointestinal stromal tumors

scientific article published on 17 November 2017

Temporal changes in phosphatidylserine expression and glucose metabolism after myocardial infarction: an in vivo imaging study in mice

scientific article published in November 2012

[68Ga]-albumin-PET in the monitoring of left ventricular function in murine models of ischemic and dilated cardiomyopathy: comparison with cardiac MRI

scientific article published on 01 August 2013

iEDDA Conjugation Reaction in Radiometal Labeling of Peptides with Ga and Cu: Unexpected Findings

scientific article published on 25 October 2018

para-Functionalized aryl-di-tert-butylfluorosilanes as potential labeling synthons for (18)F radiopharmaceuticals

scientific article published in January 2009

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