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List of works by David T Manallack

A chemogenomic analysis of ionization constants--implications for drug discovery

scientific article

A consensus neural network-based technique for discriminating soluble and poorly soluble compounds.

scientific article

A three dimensional receptor model of the dopamine D2 receptor from computer graphic analyses of D2 agonists

scientific article published on 01 June 1988

Absence of N-methyl-D-aspartate receptors on ovine cerebral microvessels

scientific article published on 01 December 1988

Active site similarity between human and Plasmodium falciparum phosphodiesterases: considerations for antimalarial drug design

scientific article published on 16 July 2011

Analysis of linear and nonlinear QSAR data using neural networks.

scientific article published on October 1994

Assessment of the pharmacological properties of 5-methoxyindole derivatives at 5-HT4 receptors

scientific article published on 16 March 2012

Calcium is the switch in the moonlighting dual function of the ligand-activated receptor kinase phytosulfokine receptor 1

scientific article

Chiral chromatography and multivariate quantitative structure-property relationships of benzimidazole sulphoxides

scientific article published on 01 February 1993

Comparison of moonlighting guanylate cyclases: roles in signal direction?

scientific article

Comparison of the properties of [3H]-D-2-amino-5-phosphonopentanoic acid and [3H]-DL-2-amino-7-phosphonoheptanoic acid binding to homogenates of rat cerebral cortex

scientific article published on 01 January 1989

Data modelling with neural networks: advantages and limitations.

scientific article published on March 1997

Database searching for thymidine and thymidylate kinase inhibitors using three-dimensional structure-based methods

scientific article published on June 2002

Design, synthesis, and testing of insulin hexamer-stabilizing agents

scientific article published on 01 October 1985

Di-tert-butyl N-[2,6-bis-(methoxy-meth-oxy)phen-yl]imino-diacetate

scientific article published on 25 March 2009

Evidence for heterogenous glycine domains but conserved multiple states of the excitatory amino acid recognition site of the NMDA receptor: regional binding studies with [3H]glycine and [3H]L-glutamate ⬇️

scientific article published on January 1, 1991

Homology modeling of human muscarinic acetylcholine receptors

scientific article

Identification of potent phosphodiesterase inhibitors that demonstrate cyclic nucleotide-dependent functions in apicomplexan parasites.

scientific article published on 4 February 2015

Inhibition of DYRK1A disrupts neural lineage specification in human pluripotent stem cells

scientific article published on 8 September 2017

Micellar electrokinetic chromatographic studies in D2O based buffer solutions

scientific article published on 01 October 1994

Modelling inhalational anaesthetics using bayesian feature selection and QSAR modelling methods.

scientific article published in August 2010

Multivariate quantitative structure-toxicity relationships in a series of dopamine mimetics

scientific article published on 01 December 1992

Phosphorylation of the dimeric cytoplasmic domain of the phytosulfokine receptor, PSKR1.

scientific article published on 3 August 2016

Platensimycin: a promising antimicrobial targeting fatty acid synthesis.

scientific article

Prediction of drug solubility from molecular structure using a drug-like training set.

scientific article published in April 2008

Regulation of sigma-receptors: high- and low-affinity agonist states, GTP shifts, and up-regulation by rimcazole and 1,3-Di(2-tolyl)guanidine

scientific article published on 01 September 1989

Scaffold hopping in de novo design. Ligand generation in the absence of receptor information.

scientific article

Selecting screening candidates for kinase and G protein-coupled receptor targets using neural networks.

scientific article published in September 2002

Statistics using neural networks: chance effects.

scientific article published in April 1993

Subchronic administration of MK-801 in the rat decreases cortical binding of [3H]D-AP5, suggesting down-regulation of the cortical N-methyl-D-aspartate receptors.

scientific article published on January 1989

Synthesis and evaluation of dithiolethiones as novel cyclooxygenase inhibitors

scientific article

Synthesis, testing and structure-activity studies on a library of 5-HT₄ ligands.

scientific article

Ten Simple Rules for Developing a MOOC

scientific article (publication date: October 2016)

The Acid/Base Profile of the Human Metabolome and Natural Products

scientific article published on 15 May 2013

The acid/base profile of agrochemicals

scientific article

The design, synthesis, and evaluation of novel conformationally rigid analogues of sialyl Lewis(x)

scientific article published on 01 December 1998

The influence and manipulation of acid/base properties in drug discovery

scientific article published on 26 April 2018

The next generation of phosphodiesterase inhibitors: structural clues to ligand and substrate selectivity of phosphodiesterases.

scientific article

The significance of acid/base properties in drug discovery

scientific article published on January 2013

The use of local surface properties for molecular superimposition.

scientific article published on 24 May 2008

Theoretical hydrogen bonding parameters for drug design.

scientific article published in January 2001

Thiophene inhibitors of PDE4: crystal structures show a second binding mode at the catalytic domain of PDE4D2

scientific article

Up-regulation of rat cortical sigma receptors after subchronic administration of rimcazole and 1,3-di(2-tolyl)guanidine

scientific article published on 01 November 1988

Use of Kv1.3 blockers for inflammatory skin conditions.

scientific article published in January 2010

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