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List of works by Angeliki Malliri

A RAC-GEF network critical for early intestinal tumourigenesis

scientific article published on 04 January 2021

A modified tandem affinity purification technique identifies that 14-3-3 proteins interact with Tiam1, an interaction which controls Tiam1 stability.

scientific article

A novel approach to the analysis of SUMOylation with the independent use of trypsin and elastase digestion followed by database searching utilising consecutive residue addition to lysine

scientific article published in January 2013

Cdk1 phosphorylates the Rac activator Tiam1 to activate centrosomal Pak and promote mitotic spindle formation.

scientific article

Centrosome separation; a careful balancing act.

scientific article published on 27 August 2015

Compartmentalisation of RAC1 signalling

scientific article published on 30 April 2018

Constitutive RAC activation is not sufficient to initiate melanocyte neoplasia but accelerates malignant progression

scientific article published on 21 January 2013

Deregulation of Rho GTPases in cancer

scientific article published on 22 April 2016

Differential Rac1 signalling by guanine nucleotide exchange factors implicates FLII in regulating Rac1-driven cell migration

scientific article published on 18 February 2016

Elevated P53 expression correlates with a history of heavy smoking in squamous cell carcinoma of the head and neck.

scientific article

Enhanced detection of ubiquitin isopeptides using reductive methylation.

scientific article published on 30 January 2013

GEFs: Dual regulation of Rac1 signaling.

scientific article published on 17 June 2016

HUWE1 is a critical colonic tumour suppressor gene that prevents MYC signalling, DNA damage accumulation and tumour initiation

scientific article published on 21 December 2016

HUWE1 ubiquitylates and degrades the RAC activator TIAM1 promoting cell-cell adhesion disassembly, migration, and invasion

scientific article published on 24 December 2014

Hace1 controls ROS generation of vertebrate Rac1-dependent NADPH oxidase complexes

scientific article published on January 2013

Mice deficient in the Rac activator Tiam1 are resistant to Ras-induced skin tumours.

scientific article

Proteomic analysis of Rac1 signaling regulation by guanine nucleotide exchange factors

scientific article published on 06 May 2016

Rac1 in human diseases: The therapeutic potential of targeting Rac1 signaling regulatory mechanisms

scientific article published on 21 July 2016

Rho family proteins in cell adhesion and cell migration.

scientific article published in June 2000

Role of Rho-family proteins in cell adhesion and cancer.

scientific article published on October 2003

SRC-induced disassembly of adherens junctions requires localized phosphorylation and degradation of the rac activator tiam1.

scientific article published on March 2009

STEF/TIAM2-mediated Rac1 activity at the nuclear envelope regulates the perinuclear actin cap.

scientific article published on 29 May 2018

SUMOylation of the GTPase Rac1 is required for optimal cell migration

scientific article

TIAM1 Antagonizes TAZ/YAP Both in the Destruction Complex in the Cytoplasm and in the Nucleus to Inhibit Invasion of Intestinal Epithelial Cells

scientific article

The Rac activator STEF (Tiam2) regulates cell migration by microtubule-mediated focal adhesion disassembly

scientific article

The diverse roles of Rac signaling in tumorigenesis

scientific article published on May 15, 2011

The interaction between CASK and the tumour suppressor Dlg1 regulates mitotic spindle orientation in mammalian epithelia

scientific article published on 15 July 2019

The rac activator Tiam1 is a Wnt-responsive gene that modifies intestinal tumor development.

scientific article published on 25 October 2005

The transcription factor AP-1 is required for EGF-induced activation of rho-like GTPases, cytoskeletal rearrangements, motility, and in vitro invasion of A431 cells.

scientific article

The tumour suppressor HACE1 controls cell migration by regulating Rac1 degradation

scientific article published on May 21, 2012

Tiam1-Rac signaling counteracts Eg5 during bipolar spindle assembly to facilitate chromosome congression

scientific article published on 25 March 2010

UHRF1-mediated tumor suppressor gene inactivation in nonsmall cell lung cancer.

scientific article published on 8 November 2010

Ultraviolet light-induced collagen degradation inhibits melanoma invasion

scientific article published on 12 May 2021

β2-syntrophin and Par-3 promote an apicobasal Rac activity gradient at cell-cell junctions by differentially regulating Tiam1 activity

scientific article