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List of works by Rob M.J. Liskamp

'Sulfo-click' for ligation as well as for site-specific conjugation with peptides, fluorophores, and metal chelators

scientific article published in January 2010

A New Chemical Probe for Proteomics of Carbohydrate-Binding Proteins

scientific article published on 01 February 2005

A New Class of Tunable Acid-Sensitive Linkers for Native Drug Release Based on the Trityl Protecting Group

scientific article published in 2022

A Selectively Deprotectable Triazacyclophane Scaffold for the Construction of Artificial Receptors

scientific article published on November 1, 2001

A combinatorial approach toward smart libraries of discontinuous epitopes of HIV gp120 on a TAC synthetic scaffold.

scientific article

A facile synthesis of the GalNAcbeta1-->4Gal target sequence of respiratory pathogens.

scientific article published in October 2005

A general approach for the non-stop solid phase synthesis of TAC-scaffolded loops towards protein mimics containing discontinuous epitopes.

scientific article published on 17 December 2008

A general sequence independent solid phase method for the site specific synthesis of multiple sulfated-tyrosine containing peptides.

scientific article

A new chemical probe for the detection of the cancer-linked galectin-3

scientific article published on 30 October 2006

A new perspective on fungal metabolites: identification of bioactive compounds from fungi using zebrafish embryogenesis as read-out

scientific article published on 26 November 2019

A novel strategy to mimic discontinuous protective epitopes using a synthetic scaffold

scientific article published on 26 July 2007

A peptide mimic of the chemotaxis inhibitory protein of Staphylococcus aureus: towards the development of novel anti-inflammatory compounds.

scientific article published on 4 August 2010

A photoswitchable ITAM peptidomimetic: synthesis and real time surface plasmon resonance (SPR) analysis of the effects of cis-trans isomerization on binding.

scientific article published on 22 October 2007

A proteinaceous fraction of wheat bran may interfere in the attachment of enterotoxigenic E. coli K88 (F4+) to porcine epithelial cells

scientific article

A versatile method for the conjugation of proteins and peptides to poly[2-(dimethylamino)ethyl methacrylate]

scientific article published on 01 July 1999

A versatile spectrophotometric protein tyrosine phosphatase assay based on 3-nitrophosphotyrosine containing substrates.

scientific article

Activity-based probes for rhomboid proteases discovered in a mass spectrometry-based assay

scientific article

Adhesion inhibition of F1C-fimbriated Escherichia coli and Pseudomonas aeruginosa PAK and PAO by multivalent carbohydrate ligands.

scientific article

Alkene/alkane-bridged mimics of the lantibiotic nisin: toward novel peptide-based antibiotics.

scientific article published in January 2009

Alpha v beta 3 integrin-targeting of intraperitoneally growing tumors with a radiolabeled RGD peptide

scientific article published on February 2007

Amino propynyl benzoic acid building block in rigid spacers of divalent ligands binding to the Syk SH2 domains with equally high affinity as the natural ligand

scientific article published in April 2003

An optimized solid phase synthesis strategy--including on-resin lactamization--of astressin, its retro-, inverso-, and retro-inverso isomers as corticotropin releasing factor antagonists

scientific article published in February 2002

An orthogonally protected CycloTriVeratrylene (CTV) as a highly pre-organized molecular scaffold for subsequent ligation of different cyclic peptides towards protein mimics.

scientific article published on 18 May 2017

Approaches to the solid phase of a cyclotriveratrylene scaffold-based tripodal library as potential artificial receptors.

scientific article

Azide-alkyne cycloaddition affording enzymatically tunable bisubstrate based inhibitors of histone acetyltransferase PCAF.

scientific article published on 4 December 2013

Backbone-modified amylin derivatives: implications for amyloid inhibitor design and as template for self-assembling bionanomaterials.

scientific article published on November 2007

Binding of a diphosphorylated-ITAM peptide to spleen tyrosine kinase (Syk) induces distal conformational changes: a hydrogen exchange mass spectrometry study.

scientific article published in July 2005

Brilliant lipids

scientific article published in January 2005

Broad-spectrum antimalarial activity of peptido sulfonyl fluorides, a new class of proteasome inhibitors.

scientific article published on 20 May 2013

CHIPS binds to the phosphorylated N-terminus of the C5a-receptor

scientific article published on 14 April 2010

Cell permeable ITAM constructs for the modulation of mediator release in mast cells.

scientific article published on 25 November 2010

Cell-penetrating bisubstrate-based protein kinase C inhibitors.

scientific article published on 8 May 2013

Characterization and activity of an immobilized antimicrobial peptide containing bactericidal PEG-hydrogel.

scientific article published on 22 August 2014

Characterization of a phosphorylated peptide and peptoid and peptoid-peptide hybrids by mass spectrometry.

scientific article published on January 2002

Chemical-biological exploration of the limits of the Ras de- and repalmitoylating machinery

scientific article

Combinatorial chemistry of hydantoins

scientific article published on 01 September 1998

Computer-assisted molecular modeling of tumor promoters: rationale for the activity of phorbol esters, teleocidin B, and aplysiatoxin.

scientific article published on January 1986

Cu(I)- and Ru(II)-mediated "click" cyclization of tripeptides toward vancomycin-inspired mimics

scientific article published on 26 May 2011

Cyclic phosphopeptides for interference with Grb2 SH2 domain signal transduction prepared by ring-closing metathesis and phosphorylation

scientific article published on 01 October 2003

Cyclotriveratrylene (CTV) as a new chiral triacid scaffold capable of inducing triple helix formation of collagen peptides containing either a native sequence or Pro-Hyp-Gly repeats

scientific article published in October 2002

Delayed fibril formation of amylin(20-29) by incorporation of alkene dipeptidosulfonamide isosteres obtained by solid phase olefin cross metathesis.

scientific article published on 6 November 2007

Design, Synthesis, and Evaluation of a Diazirine Photoaffinity Probe for Ligand-Based Receptor Capture Targeting G Protein-Coupled Receptors

scientific article published on 04 December 2018

Detection of galectin-3 by novel peptidic photoprobes

scientific article published on 21 October 2006

Detection of pathogenic Streptococcus suis bacteria using magnetic glycoparticles.

scientific article published on 22 March 2010

Determination of sparsomycin in plasma and urine of the dog by means of reversed-phase high-performance liquid chromatography and first pharmacokinetic results

scientific article published on 01 June 1983

Development of a novel chemical probe for the selective enrichment of phosphorylated serine- and threonine-containing peptides

scientific article published in December 2005

Development of selective bisubstrate-based inhibitors against protein kinase C (PKC) isozymes by using dynamic peptide microarrays

scientific article published on 01 August 2009

Different Membrane Anchoring Positions of Tryptophan and Lysine in Synthetic Transmembrane α-Helical Peptides

scientific article published in Journal of Biological Chemistry

Directed modulation of protein kinase C isozyme selectivity with bisubstrate-based inhibitors.

scientific article

Discovery and in vivo evaluation of new melanocortin-4 receptor-selective peptides.

scientific article

Effects of linker variation on the in vitro and in vivo characteristics of an 111In-labeled RGD peptide

scientific article published on January 2007

Efficient microwave-assisted synthesis of multivalent dendrimeric peptides using cycloaddition reaction (click) chemistry

scientific article published on 19 August 2005

Efficient synthesis of protein mimics by sequential native chemical ligation

scientific article published on 7 April 2014

Enhanced membrane pore formation by multimeric/oligomeric antimicrobial peptides

scientific article published on 18 October 2007

Enzymatic synthesis of C-terminal arylamides of amino acids and peptides.

scientific article

Glucocorticoid-loaded core-cross-linked polymeric micelles with tailorable release kinetics for targeted therapy of rheumatoid arthritis.

scientific article published on 12 June 2012

Highly efficient coupling of beta-substituted aminoethane sulfonyl azides with thio acids, toward a new chemical ligation reaction

scientific article published on 01 March 2005

ITAM-derived phosphopeptide-containing dendrimers as multivalent ligands for Syk tandem SH2 domain.

scientific article published on 7 August 2009

Immobilization By Surface Conjugation Of Cyclic Peptides For Ef-fective Mimicry Of The HCV-Envelope E2 Protein As A Strategy Towards Synthetic Vaccines.

scientific article

Imprinted polymers displaying high affinity for sulfated protein fragments

scientific article published on 05 July 2012

Improved targeting of the alpha(v)beta (3) integrin by multimerisation of RGD peptides

scientific article published on 15 August 2006

Improving the aqueous solubility of HCV-E2 glycoprotein epitope mimics by cyclization using POLAR hinges

scientific article published on 01 January 2020

Improving the biological activity of the antimicrobial peptide anoplin by membrane anchoring through a lipophilic amino acid derivative.

scientific article published on 9 May 2013

Increased stability of peptidesulfonamide peptidomimetics towards protease catalyzed degradation

scientific article published on 01 June 1999

Influence of flanking residues on tilt and rotation angles of transmembrane peptides in lipid bilayers. A solid-state 2H NMR study.

scientific article published in January 2005

Influence of trifluoroethanol on membrane interfacial anchoring interactions of transmembrane alpha-helical peptides.

scientific article

Inhibition of Streptococcus suis adhesion by dendritic galabiose compounds at low nanomolar concentration.

scientific article

Inhibition of amyloid fibril formation of human amylin by N-alkylated amino acid and alpha-hydroxy acid residue containing peptides

scientific article published in September 2002

Investigating the dynamic nature of the interactions between nuclear proteins and histones upon DNA damage using an immobilized peptide chemical proteomics approach

scientific article published on September 2006

Islet amyloid polypeptide inserts into phospholipid monolayers as monomer

scientific article published on 21 December 2005

Limited plasticity in T cell recognition of modified T cell receptor contact residues in MHC class II bound peptides.

scientific article published in February 2005

Lipid dependence of membrane anchoring properties and snorkeling behavior of aromatic and charged residues in transmembrane peptides.

scientific article published in June 2002

Major histocompatibility complex class II binding characteristics of peptoid-peptide hybrids

scientific article published on 01 June 2002

Microwave-assisted click polymerization for the synthesis of Abeta(16-22) cyclic oligomers and their self-assembly into polymorphous aggregates

scientific article published on 27 August 2009

Microwave-assisted, tin-mediated, regioselective 3-O-alkylation of galactosides

Molecular Construction of Sulfonamide Antisense Oligonucleotides

scientific article published on 19 August 2019

Molecular construction of HIV-gp120 discontinuous epitope mimics by assembly of cyclic peptides on an orthogonal alkyne functionalized TAC-scaffold.

scientific article published on 10 November 2015

Multivalent carbohydrate recognition on a glycodendrimer-functionalized flow-through chip.

scientific article published in July 2008

Mutual influence of backbone proline substitution and lipophilic tail character on the biological activity of simplified analogues of caspofungin

scientific article

N-terminal residues of the chemotaxis inhibitory protein of Staphylococcus aureus are essential for blocking formylated peptide receptor but not C5a receptor

scientific article published in November 2004

Nanomolar affinity, iminosugar-based chemical probes for specific labeling of lysosomal glucocerebrosidase

scientific article published on 31 October 2009

New properties of wheat bran: anti-biofilm activity and interference with bacteria quorum-sensing systems

scientific article published on 04 April 2014

Peptide Microarrays for Real-Time Kinetic Profiling of Tyrosine Phosphatase Activity of Recombinant Phosphatases and Phosphatases in Lysates of Cells or Tissue Samples.

scientific article

Peptide transformation leading to peptide-peptidosulfonamide hybrids and oligo peptidosulfonamides.

scientific article published on January 2004

Peptides and proteins as a continuing exciting source of inspiration for peptidomimetics

scientific article published on 12 July 2011

Peptides: Bicycling into cells

scientific article published on 01 October 2014

Peptido Sulfonyl Fluorides as New Powerful Proteasome Inhibitors

scientific article published on 13 December 2012

Peptidomimetic ligands for the tandem SH2 domain of the Syk protein involved in signal transduction.

scientific article published in January 2009

Peptoid-peptide hybrids as potent novel melanocortin receptor ligands

scientific article published on 01 June 2005

Photo-crosslinking analysis of preferential interactions between a transmembrane peptide and matching lipids

scientific article published in April 2004

Photocrosslinking and click chemistry enable the specific detection of proteins interacting with phospholipids at the membrane interface

scientific article published in January 2009

Polar Hinges as Functionalized Conformational Constraints in (Bi)cyclic Peptides.

scientific article

Possibilities and limitations in the rational design of modified peptides for T cell mediated immunotherapy.

scientific article published in February 2005

Potent and Highly Selective Inhibitors of the Proteasome Trypsin-like Site by Incorporation of Basic Side Chain Containing Amino Acid Derived Sulfonyl Fluorides

scientific article published on 13 June 2018

Potential peptidic proteasome inhibitors by incorporation of an electrophilic trap based on amino acid derived α-substituted sulfonyl fluorides

scientific article published on 12 July 2017

Potential scorpionate antibiotics: targeted hydrolysis of lipid II containing model membranes by vancomycin-TACzyme conjugates and modulation of their antibacterial activity by Zn-ions.

scientific article

Pre-organization induced synthesis of a crossed alkene-bridged nisin Z DE-ring mimic by ring-closing metathesis.

scientific article

Preparation of N(G)-substituted L-arginine analogues suitable for solid phase peptide synthesis.

scientific article published on 28 August 2008

Preparation of novel alkylated arginine derivatives suitable for click-cycloaddition chemistry and their incorporation into pseudosubstrate- and bisubstrate-based kinase inhibitors.

scientific article published on 4 February 2010

Probing the lipid-protein interface using model transmembrane peptides with a covalently linked acyl chain

scientific article

Proteasome inhibition by new dual warhead containing peptido vinyl sulfonyl fluorides.

scientific article published on 24 May 2016

Protein flexibility and ligand rigidity: a thermodynamic and kinetic study of ITAM-based ligand binding to Syk tandem SH2.

scientific article

Rapid screening of lectins for multivalency effects with a glycodendrimer microarray

scientific article published on September 2010

Real-Time Monitoring of the Dephosphorylating Activity of Protein Tyrosine Phosphatases Using Microarrays with 3-Nitrophosphotyrosine Substrates

scientific article published on 17 September 2013

Replacement of the intervening amino acid sequence of a Syk-binding diphosphopeptide by a nonpeptide spacer with preservation of high affinity

scientific article published on 01 March 2002

Resin-bound sulfonyl azides: efficient loading and activation strategy for the preparation of the N-acyl sulfonamide linker

scientific article published on 12 May 2007

Rigidified multivalent lactose molecules and their interactions with mammalian galectins: a route to selective inhibitors.

scientific article

Ring-closing alkyne metathesis approach toward the synthesis of alkyne mimics of thioether A-, B-, C-, and DE-ring systems of the lantibiotic nisin Z

scientific article published on 01 July 2005

Ring-closing metathesis for the synthesis of side chain knotted pentapeptides inspired by vancomycin.

scientific article published on 24 August 2004

Role of solution conformation and flexibility of short peptide ligands that bind to the p56(lck) SH2 domain.

scientific article

Rolling Loop Scan: An Approach Featuring Ring-Closing Metathesis for Generating Libraries of Peptides with Molecular Shapes Mimicking Bioactive Conformations or Local Folding of Peptides and Proteins.

scientific article

Scaffold optimization in discontinuous epitope containing protein mimics of gp120 using smart libraries

scientific article published on April 28, 2013

Scaffolded amino acids as a close structural mimic of type-3 copper binding sites

scientific article

Scaffolded multiple cyclic peptide libraries for protein mimics by native chemical ligation.

scientific article

Scalable purification of the lantibiotic nisin and isolation of chemical/enzymatic cleavage fragments suitable for semi-synthesis.

scientific article published on 11 September 2013

Selective enrichment of Ser-/Thr-phosphorylated peptides in the presence of Ser-/Thr-glycosylated peptides

scientific article published on 01 December 2006

Selective inhibition of the immunoproteasome by ligand-induced crosslinking of the active site

scientific article

Self-assembly of amylin(20-29) amide-bond derivatives into helical ribbons and peptide nanotubes rather than fibrils.

scientific article published in May 2006

Semi-synthesis of biologically active nisin hybrids composed of the native lanthionine ABC-fragment and a cross-stapled synthetic DE-fragment

scientific article published on 2 August 2014

Sensitivity of single membrane-spanning alpha-helical peptides to hydrophobic mismatch with a lipid bilayer: effects on backbone structure, orientation, and extent of membrane incorporation.

scientific article published in April 2001

Solid-phase synthesis of oligourea peptidomimetics employing the Fmoc protection strategy.

scientific article published in December 2001

Spacer effects on in vivo properties of DOTA-conjugated dimeric [Tyr3]octreotate peptides synthesized by a "Cu(I)-click" and "sulfo-click" ligation method

scientific article published on 15 February 2011

Stabilization of peptide guinea pig myelin basic protein 72-85 by N-terminal acetylation-implications for immunological studies

scientific article

Step-wise and pre-organization induced synthesis of a crossed alkene-bridged nisin Z DE-ring mimic by ring-closing metathesis

scientific article published on 07 February 2007

Strong Inhibition of Cholera Toxin by Multivalent GM1 Derivatives

scientific article published on 01 September 2007

Strong inhibition of cholera toxin binding by galactose dendrimers.

scientific article published on 24 September 2007

Structural analysis of high affinity divalent phosphopeptide hybrids of spleen tyrosine kinase

Structural insight into the recognition of the H3K4me3 mark by the TFIID subunit TAF3.

scientific article

Structure of the Tyrosine-sulfated C5a Receptor N Terminus in Complex with Chemotaxis Inhibitory Protein of Staphylococcus aureus

scientific article

Structure-activity relationships of sparsomycin and its analogues. Inhibition of peptide bond formation in cell-free systems and of L1210 and bacterial cell growth.

scientific article

Structure-activity relationships of sparsomycin and its analogues. Octylsparsomycin: the first analogue more active than sparsomycin

scientific article published on 01 March 1984

Structure-activity studies on the corticotropin releasing factor antagonist astressin, leading to a minimal sequence necessary for antagonistic activity

scientific article published in March 2004

Sulfoxide configuration in sparsomycin determines time-dependent and competitive inhibition of peptidyl transferase

scientific article published on 01 December 1984

Surface plasmon resonance thermodynamic and kinetic analysis as a strategic tool in drug design. Distinct ways for phosphopeptides to plug into Src- and Grb2 SH2 domains.

scientific article published in February 2005

Switching between low and high affinity for the Syk tandem SH2 domain by irradiation of azobenzene containing ITAM peptidomimetics.

scientific article published in October 2009

Synthesis and applications of biomedical and pharmaceutical polymers via click chemistry methodologies.

scientific article

Synthesis and biological activity of N-terminal lipidated and/or fluorescently labeled conjugates of astressin as corticotropin releasing factor antagonists.

scientific article published on October 2004

Synthesis and biological activity of polygalloyl-dendrimers as stable tannic acid mimics

scientific article published in June 2002

Synthesis and biological evaluation of novel irreversible serine protease inhibitors using amino acid based sulfonyl fluorides as an electrophilic trap

scientific article published on 13 February 2011

Synthesis and biological evaluation of potent alphavbeta3-integrin receptor antagonists

scientific article published on 01 November 2006

Synthesis and cellular penetration properties of new phosphonium based cationic amphiphilic peptides

scientific article published on 09 May 2018

Synthesis and characterization of biodegradable peptide-based polymers prepared by microwave-assisted click chemistry.

scientific article

Synthesis and characterization of enzymatically biodegradable PEG and peptide-based hydrogels prepared by click chemistry

scientific article published in June 2010

Synthesis and characterization of tailorable biodegradable thermoresponsive methacryloylamide polymers based on l-serine and l-threonine alkyl esters

scholarly article by Maarten van Dijk et al published May 2010 in Polymer

Synthesis and cholera toxin binding properties of a lactose-2-aminothiazoline conjugate

scientific article

Synthesis and cholera toxin binding properties of multivalent GM1 mimics

scientific article published on 30 June 2004

Synthesis and evaluation of TAC-based inhibitors of papain as mimics of cystatin B

scientific article published on 01 November 2007

Synthesis and evaluation of chloromethyl sulfoxides as a new class of selective irreversible cysteine protease inhibitors

scientific article published on 22 August 2007

Synthesis and evaluation of new thiodigalactoside-based chemical probes to label galectin-3.

scientific article

Synthesis and evaluation of novel macrocyclic antifungal peptides

scientific article published on 22 August 2011

Synthesis and screening of libraries of synthetic tripodal receptor molecules with three different amino acid or peptide arms: identification of iron binders

scientific article

Synthesis and structural characterization of the individual diastereoisomers of a cross-stapled alkene-bridged nisin DE-ring mimic.

scientific article published in November 2013

Synthesis and structural investigations of N-alkylated beta-peptidosulfonamide-peptide hybrids of the amyloidogenic amylin(20-29) sequence: Implications of supramolecular folding for the design of peptide-based bionanomaterials.

scientific article

Synthesis of 1,5-triazole bridged vancomycin CDE-ring bicyclic mimics using RuAAC macrocyclization

scientific article

Synthesis of DOTA-conjugated multimeric [Tyr3]octreotide peptides via a combination of Cu(I)-catalyzed "click" cycloaddition and thio acid/sulfonyl azide "sulfo-click" amidation and their in vivo evaluation.

scientific article published on May 2010

Synthesis of DOTA-conjugated multivalent cyclic-RGD peptide dendrimers via 1,3-dipolar cycloaddition and their biological evaluation: implications for tumor targeting and tumor imaging purposes

scientific article published on 29 January 2007

Synthesis of a novel potent cyclic peptide MC4-ligand by ring-closing metathesis

scientific article published on 01 July 2005

Synthesis of alkyne-bridged cyclic tripeptides toward constrained mimics of vancomycin

scientific article published in March 2006

Synthesis of bicyclic alkene-/alkane-bridged nisin mimics by ring-closing metathesis and their biochemical evaluation as lipid II binders: toward the design of potential novel antibiotics.

scientific article published on September 2007

Synthesis of cyclic (alpha(2)beta)-tripeptides as potential peptide turn mimetics

scientific article published on 01 June 2002

Synthesis of cyclic peptides by ring-closing metathesis

scientific article published on 01 September 2000

Synthesis of cyclic peptides containing a thioester handle for native chemical ligation

scientific article published on 05 November 2012

Synthesis of cyclic peptidosulfonamides as scaffolds for MC4 pharmacophoric groups.

scientific article published in January 2005

Synthesis of cyclic peptidosulfonamides by ring-closing metathesis

scientific article

Synthesis of leukotriene B4 antagonists labeled with In-111 or Tc-99m to image infectious and inflammatory foci

scientific article

Synthesis of multivalent Streptococcus suis adhesion inhibitors by enzymatic cleavage of polygalacturonic acid and 'click' conjugation.

scientific article published on 29 February 2008

Synthesis of nisin AB dicarba analogs using ring-closing metathesis: influence of sp(3) versus sp(2) hybridization of the α-carbon atom of residues dehydrobutyrine-2 and dehydroalanine-5 on the lipid II binding affinity.

scientific article published on June 2015

Synthesis of peptide-based polymers by microwave-assisted cycloaddition backbone polymerization

scientific article published on 01 February 2007

Synthesis of pyrazole containing α-amino acids via a highly regioselective condensation/aza-Michael reaction of β-aryl α,β-unsaturated ketones

article

Synthesis of the TACO scaffold as a new selectively deprotectable conformationally restricted triazacyclophane based scaffold

scientific article published on 23 May 2014

Synthesis, antimicrobial activity, and membrane permeabilizing properties of C-terminally modified nisin conjugates accessed by CuAAC

scientific article published on 05 December 2013

Synthetic antibody protein mimics of infliximab by molecular scaffolding on novel CycloTriVeratrilene (CTV) derivatives

scientific article published on 01 July 2018

TAC-scaffolded tripeptides as artificial hydrolytic receptors: a combinatorial approach toward esterase mimics

scientific article

Tailoring Polyethers for Post-polymerization Functionalization by Cross Metathesis.

scientific article published on 30 March 2018

Tannic acid mimicking dendrimers as small intestine submucosa stabilizing nanomordants.

scientific article published on 18 August 2005

Targeted Covalent Inhibition of Prolyl Oligopeptidase (POP): Discovery of Sulfonylfluoride Peptidomimetics

scientific article published on 17 May 2018

The Effects of Hydrophobic Mismatch between Phosphatidylcholine Bilayers and Transmembrane α-Helical Peptides Depend on the Nature of Interfacially Exposed Aromatic and Charged Residues†

scientific article published on 01 July 2002

The N-terminal fragment of human islet amyloid polypeptide is non-fibrillogenic in the presence of membranes and does not cause leakage of bilayers of physiologically relevant lipid composition

scientific article published on 4 June 2010

The State of the Art of Chemical Biology

scientific article published on 01 January 2009

The alphaM1 segment of the nicotinic acetylcholine receptor exhibits conformational flexibility in a membrane environment.

scientific article published in October 2004

The alphaM1 transmembrane segment of the nicotinic acetylcholine receptor interacts strongly with model membranes

scientific article published in February 2004

The filament-specific Rep1-1 repellent of the phytopathogen Ustilago maydis forms functional surface-active amyloid-like fibrils.

scientific article published on 21 January 2009

The presence of C/EBPα and its degradation are both required for TRIB2-mediated leukaemia.

scientific article

The role of the disulfide bond in the interaction of islet amyloid polypeptide with membranes

scientific article published on 6 January 2010

The structure of the C5a receptor-blocking domain of chemotaxis inhibitory protein of Staphylococcus aureus is related to a group of immune evasive molecules

scientific article published on 23 September 2005

The vancomycin-nisin(1-12) hybrid restores activity against vancomycin resistant Enterococci

scientific article

Thermodynamics of phosphotyrosine peptide-peptoid hybrids binding to the p56lck SH2 domain.

scientific article published in July 2010

Thermosensitive Peptide-Hybrid ABC Block Copolymers Obtained by ATRP: Synthesis, Self-Assembly, and Enzymatic Degradation

article published in 2012

Tilt angles of transmembrane model peptides in oriented and non-oriented lipid bilayers as determined by 2H solid-state NMR.

scientific article

Transformation of the amyloidogenic peptide amylin(20-29) into its corresponding peptoid and retropeptoid: access to both an amyloid inhibitor and template for self-assembled supramolecular tapes

scientific article published on 24 January 2007

Triazacyclophane (TAC)-scaffolded histidine and aspartic acid residues as mimics of non-heme metalloenzyme active sites

scientific article published on 19 December 2011

Trivalent ultrashort lipopeptides are potent pH dependent antifungal agents

scientific article published on February 2012

Unusual binding of Grb2 protein to a bivalent polyproline-ligand immobilized on a SPR sensor: intermolecular bivalent binding.

scientific article published on 15 November 2012

Versatile conjugation of octreotide to dendrimers by cycloaddition ("click") chemistry to yield high-affinity multivalent cyclic Peptide dendrimers.

scientific article

Versatile convergent synthesis of a three peptide loop containing protein mimic of whooping cough pertactin by successive Cu(I)-catalyzed azide alkyne cycloaddition on an orthogonal alkyne functionalized TAC-scaffold.

scientific article published on 6 March 2014

pH controlled aggregation morphology of Abeta(16-22): formation of peptide nanotubes, helical tapes and amyloid fibrils.

scientific article published in January 2009

pH-controlled aggregation polymorphism of amyloidogenic Aβ(16-22): insights for obtaining peptide tapes and peptide nanotubes, as function of the N-terminal capping moiety.

scientific article published on 25 July 2014

β-Sheet Structured β-Amyloid(1-40) Perturbs Phosphatidylcholine Model Membranes

article