List of works - Manuel M Paz

A New Mechanism of Action for the Anticancer Drug Mitomycin C: Mechanism-Based Inhibition of Thioredoxin Reductase ⬇️

scientific article published on June 25, 2012

Acetone promoted 1,4-migration of an alkoxycarbonyl group on a syn-1,2-diamine

scientific article published on 3 January 2017

Cross-linking of dithiols by mitomycin C.

scientific article published on August 2010

Interdependent Sequence Selectivity and Diastereoselectivity in the Alkylation of DNA by Decarbamoylmitomycin C

scientific article published on 10 August 2018

Isolation and Rationale for the Formation of Isomeric Decarbamoylmitomycin C- N6-deoxyadenosine Adducts in DNA

scientific article published on 02 August 2018

Mapping DNA adducts of mitomycin C and decarbamoyl mitomycin C in cell lines using liquid chromatography/ electrospray tandem mass spectrometry.

scientific article published on December 2008

Mitomycin C linked to DNA minor groove binding agents: synthesis, reductive activation, DNA binding and cross-linking properties and in vitro antitumor activity

scientific article published on 01 December 1999

Mitomycin dimers: polyfunctional cross-linkers of DNA.

scientific article

Monoalkylation of DNA by reductively activated FR66979

scientific article published on 01 January 2000

Polyhomologation: Synthesis of Novel Polymethylene Architectures by a Living Polymerization of Dimethylsulfoxonium Methylide

scientific article published on 01 June 1998

Reaction of reductively activated mitomycin C with aqueous bicarbonate: Isolation and characterization of an oxazolidinone derivative of cis-1-hydroxy-2,7-diaminomitosene.

scientific article published on 15 November 2009

Reductive activation of mitomycin A by thiols

scientific article published on 01 September 2001

Reductive activation of mitomycins A and C by vitamin C ⬇️

scientific article published on April 6, 2013

Relative toxicities of DNA cross-links and monoadducts: new insights from studies of decarbamoyl mitomycin C and mitomycin C

scientific article published on 01 November 2002

Selective activation of mitomycin A by thiols to form DNA cross-links and monoadducts: biochemical basis for the modulation of mitomycin cytotoxicity by the quinone redox potential.

scientific article published in August 2001

Sequence-Dependent Diastereospecific and Diastereodivergent Crosslinking of DNA by Decarbamoylmitomycin C.

scientific article published on 5 March 2018

Synthesis of Mitomycin C and Decarbamoylmitomycin C N(2) deoxyguanosine-adducts

scientific article published on 11 February 2016

Synthesis of a major mitomycin C DNA adduct via a triaminomitosene

scientific article published on 25 September 2012

The boron-catalyzed polymerization of dimethylsulfoxonium methylide. A living polymethylene synthesis.