List of works - Eric C Schirmer

A flow cytometry-based screen of nuclear envelope transmembrane proteins identifies NET4/Tmem53 as involved in stress-dependent cell cycle withdrawal.

scientific article

Abnormal proliferation and spontaneous differentiation of myoblasts from a symptomatic female carrier of X-linked Emery-Dreifuss muscular dystrophy

scientific article

Amyloid fibres of Sup35 support a prion-like mechanism of inheritance in yeast

scientific article published on 01 August 1998

An Arabidopsis Heat Shock Protein Complements a Thermotolerance Defect in Yeast

scientific article published in 1994

An Arabidopsis heat shock protein complements a thermotolerance defect in yeast.

scientific article published in December 1994

Analysis of RNA-Seq datasets reveals enrichment of tissue-specific splice variants for nuclear envelope proteins

scientific article published on 01 January 2018

Anchoring a Leviathan: How the Nuclear Membrane Tethers the Genome

scientific article

Breaking the scale: how disrupting the karyoplasmic ratio gives cancer cells an advantage for metastatic invasion

scientific article published on 17 November 2017

Cancer Biology and the Nuclear Envelope

Cancer biology and the nuclear envelope: a convoluted relationship.

scientific article published on 28 January 2012

Casting a Wider Net: Differentiating between Inner Nuclear Envelope and Outer Nuclear Envelope Transmembrane Proteins

scientific article published on 23 October 2019

Cell-specific and lamin-dependent targeting of novel transmembrane proteins in the nuclear envelope.

scientific article published on 21 January 2010

Cellular and growth-factor requirements for the replication of human herpesvirus 6 in primary lymphocyte cultures

scientific article published on January 1990

Comparative proteomic analyses of the nuclear envelope and pore complex suggests a wide range of heretofore unexpected functions

scientific article published on 27 September 2008

Considering discrete protein pools when measuring the dynamics of nuclear membrane proteins

scientific article published in January 2013

Constrained release of lamina-associated enhancers and genes from the nuclear envelope during T-cell activation facilitates their association in chromosome compartments

scientific article

Constrained release of lamina-associated enhancers and genes from the nuclear envelope during T-cell activation facilitates their association in chromosome compartments

article

Defining a pathway of communication from the C-terminal peptide binding domain to the N-terminal ATPase domain in a AAA protein

scientific article published in April 2002

Differentiation between two distinct classes of viruses now classified as human herpesvirus 6.

scientific article published on July 1991

Dominant gain-of-function mutations in Hsp104p reveal crucial roles for the middle region

scientific article

Energy- and temperature-dependent transport of integral proteins to the inner nuclear membrane via the nuclear pore

scientific article

FG repeats facilitate integral protein trafficking to the inner nuclear membrane

scientific article published on September 2011

GRASP: a novel heparin-binding serum glycoprotein that mediates oligodendrocyte-substratum adhesion

scientific article published in November 1994

Guilt by association: the nuclear envelope proteome and disease

scientific article published on 21 June 2006

HSP100/Clp proteins: a common mechanism explains diverse functions

scientific article published on August 1996

Herpes simplex virus ICP27 protein directly interacts with the nuclear pore complex through Nup62, inhibiting host nucleocytoplasmic transport pathways

scientific article

Host Vesicle Fusion Protein VAPB Contributes to the Nuclear Egress Stage of Herpes Simplex Virus Type-1 (HSV-1) Replication

scientific article published on 03 February 2019

Host Vesicle Fusion Proteins VAPB, Rab11b and Rab18 Contribute to HSV-1 Infectivity by Facilitating Egress through the Nuclear Membrane

Identification of novel integral membrane proteins of the nuclear envelope with potential disease links using subtractive proteomics

scientific article

Immunohistochemistry on a panel of Emery-Dreifuss muscular dystrophy samples reveals nuclear envelope proteins as inconsistent markers for pathology.

scientific article published on 21 December 2016

In vitro activation of human herpesviruses 6 and 7 from latency

scientific article

Inner nuclear membrane protein transport is mediated by multiple mechanisms.

scientific article published on December 2008

Interactions of the chaperone Hsp104 with yeast Sup35 and mammalian PrP.

scientific article

Involvement of the lamin rod domain in heterotypic lamin interactions important for nuclear organization

scientific article

Isolation of a new herpesvirus from human CD4+ T cells

scientific article

Isolation, Proteomic Analysis, and Microscopy Confirmation of the Liver Nuclear Envelope Proteome

scientific article published on 01 January 2016

LINC'ing form and function at the nuclear envelope.

scientific article

Lamin A molecular compression and sliding as mechanisms behind nucleoskeleton elasticity

scientific article published on 11 July 2019

Lipids contribute to epigenetic control via chromatin structure and functions

Many mechanisms, one entrance: membrane protein translocation into the nucleus

scientific article published on 12 February 2012

Microinjection of Antibodies Targeting the Lamin A/C Histone-Binding Site Blocks Mitotic Entry and Reveals Separate Chromatin Interactions with HP1, CenpB and PML.

scientific article published on 25 March 2017

Mitotic post-translational modifications of histones promote chromatin compaction in vitro

scientific article published on September 2017

MudPIT: A powerful proteomics tool for discovery

scientific article

NET23/STING promotes chromatin compaction from the nuclear envelope

scientific article

NETs and cell cycle regulation

scientific article published on January 2014

Navigating the Nuclear Envelope: One or Multiple Transport Mechanisms for Integral Membrane Proteins?

Nuclear envelope influences on genome organization

scientific article published on 01 February 2010

Nuclear envelope: connecting structural genome organization to regulation of gene expression

scientific article published on January 2014

Nuclear import of adenovirus DNA in vitro involves the nuclear protein import pathway and hsc70.

scientific article published on February 2000

Nuclear membrane diversity: underlying tissue-specific pathologies in disease?

scientific article published on 24 June 2015

Nuclear membrane proteins with potential disease links found by subtractive proteomics

scientific article (publication date: 5 September 2003)

Nucleoplasmic signals promote directed transmembrane protein import simultaneously via multiple channels of nuclear pores

scientific article published on 04 May 2020

Nup50, a nucleoplasmically oriented nucleoporin with a role in nuclear protein export

scientific article

Optimization of DamID for use in primary cultures of mouse hepatocytes

article

Organellar proteomics: the prizes and pitfalls of opening the nuclear envelope.

scientific article

Organelle proteome variation among different cell types: lessons from nuclear membrane proteins

scientific article published on January 2007

Proteins that associate with lamins: many faces, many functions.

scientific article published on 24 March 2007

Purification of Lamins and Soluble Fragments of NETs

scientific article published on 28 September 2015

Purification of Nuclei and Preparation of Nuclear Envelopes from Skeletal Muscle

scientific article published on 01 January 2008

Reduction of a 4q35-encoded nuclear envelope protein in muscle differentiation

scientific article published on 28 August 2009

Repo-Man/PP1 regulates heterochromatin formation in interphase.

scientific article published on 16 January 2017

Self-seeded fibers formed by Sup35, the protein determinant of [PSI+], a heritable prion-like factor of S. cerevisiae.

scientific article

Several novel nuclear envelope transmembrane proteins identified in skeletal muscle have cytoskeletal associations

scientific article

Single-point single-molecule FRAP distinguishes inner and outer nuclear membrane protein distribution

scientific article

Spatial Genome Organization: From Development to Disease

scientific article published on 21 March 2019

Spatial Organization of the Nucleus Compartmentalizes and Regulates the Genome

Specific nuclear envelope transmembrane proteins can promote the location of chromosomes to and from the nuclear periphery.

scientific article published on 15 February 2013

Subcellular Fractionation and Proteomics of Nuclear Envelopes

scientific article published on 01 January 2008

Subunit interactions influence the biochemical and biological properties of Hsp104

scholarly article

System analysis shows distinct mechanisms and common principles of nuclear envelope protein dynamics

scientific article

T-cell activation is required for efficient replication of human herpesvirus 6.

scientific article published on September 1990

TMEM120A and B: Nuclear Envelope Transmembrane Proteins Important for Adipocyte Differentiation

scientific article

Telomere elongation through hTERT immortalization leads to chromosome repositioning in control cells and genomic instability in Hutchinson‐Gilford progeria syndrome fibroblasts, expressing a novel SUN1 isoform

scientific article published on 07 January 2019

The ATPase activity of Hsp104, effects of environmental conditions and mutations.

scientific article published in June 1998

The Application of DamID to Identify Peripheral Gene Sequences in Differentiated and Primary Cells.

scientific article published on January 2016

The Kaposi's sarcoma-associated herpesvirus ORF57 protein: a pleurotropic regulator of gene expression

article

The NEMP family supports metazoan fertility and nuclear envelope stiffness

scientific article published on 28 August 2020

The Nuclear Envelope

The apparent absence of lamin B1 and emerin in many tissue nuclei is due to epitope masking

scientific article published on 01 June 2005

The cell-wide web coordinates cellular processes by directing site-specific Ca flux across cytoplasmic nanocourses

scientific article published on 24 May 2019

The epigenetics of nuclear envelope organization and disease

scientific article published on 03 August 2008

The increasing relevance of nuclear envelope myopathies

scientific article

The leukocyte nuclear envelope proteome varies with cell activation and contains novel transmembrane proteins that affect genome architecture ⬇️

scientific article

The nuclear envelope and cancer: a diagnostic perspective and historical overview.

scientific article published on January 2014

The nuclear envelope as a chromatin organizer

scientific article

The nuclear envelope proteome differs notably between tissues

scientific article

The nuclear membrane proteome: extending the envelope.

scientific article

The stability of the nuclear lamina polymer changes with the composition of lamin subtypes according to their individual binding strengths

scientific article published on 27 July 2004

Tissue specificity in the nuclear envelope supports its functional complexity.

scientific article

Tissue-Specific Gene Repositioning by Muscle Nuclear Membrane Proteins Enhances Repression of Critical Developmental Genes during Myogenesis.

scientific article published on 31 May 2016

Tissue-specific NETs alter genome organization and regulation even in a heterologous system

scientific article published on 3 January 2017

Use of Sequential Chemical Extractions to Purify Nuclear Membrane Proteins for Proteomics Identification

scientific article published on 01 January 2009

Whole-epigenome analysis in multiple myeloma reveals DNA hypermethylation of B cell-specific enhancers.

scientific article

[34] Purification and properties of Hsp104 from yeast

scientific article published on 01 January 1998

List of works by Eric C Schirmer

A flow cytometry-based screen of nuclear envelope transmembrane proteins identifies NET4/Tmem53 as involved in stress-dependent cell cycle withdrawal.

Abnormal proliferation and spontaneous differentiation of myoblasts from a symptomatic female carrier of X-linked Emery-Dreifuss muscular dystrophy

Amyloid fibres of Sup35 support a prion-like mechanism of inheritance in yeast

An Arabidopsis Heat Shock Protein Complements a Thermotolerance Defect in Yeast

An Arabidopsis heat shock protein complements a thermotolerance defect in yeast.

Analysis of RNA-Seq datasets reveals enrichment of tissue-specific splice variants for nuclear envelope proteins

Anchoring a Leviathan: How the Nuclear Membrane Tethers the Genome

Breaking the scale: how disrupting the karyoplasmic ratio gives cancer cells an advantage for metastatic invasion

Cancer Biology and the Nuclear Envelope

Cancer biology and the nuclear envelope: a convoluted relationship.

Casting a Wider Net: Differentiating between Inner Nuclear Envelope and Outer Nuclear Envelope Transmembrane Proteins

Cell-specific and lamin-dependent targeting of novel transmembrane proteins in the nuclear envelope.

Cellular and growth-factor requirements for the replication of human herpesvirus 6 in primary lymphocyte cultures

Comparative proteomic analyses of the nuclear envelope and pore complex suggests a wide range of heretofore unexpected functions

Considering discrete protein pools when measuring the dynamics of nuclear membrane proteins

Constrained release of lamina-associated enhancers and genes from the nuclear envelope during T-cell activation facilitates their association in chromosome compartments

Constrained release of lamina-associated enhancers and genes from the nuclear envelope during T-cell activation facilitates their association in chromosome compartments

Defining a pathway of communication from the C-terminal peptide binding domain to the N-terminal ATPase domain in a AAA protein

Differentiation between two distinct classes of viruses now classified as human herpesvirus 6.

Dominant gain-of-function mutations in Hsp104p reveal crucial roles for the middle region

Energy- and temperature-dependent transport of integral proteins to the inner nuclear membrane via the nuclear pore

FG repeats facilitate integral protein trafficking to the inner nuclear membrane

GRASP: a novel heparin-binding serum glycoprotein that mediates oligodendrocyte-substratum adhesion

Guilt by association: the nuclear envelope proteome and disease

HSP100/Clp proteins: a common mechanism explains diverse functions

Herpes simplex virus ICP27 protein directly interacts with the nuclear pore complex through Nup62, inhibiting host nucleocytoplasmic transport pathways

Host Vesicle Fusion Protein VAPB Contributes to the Nuclear Egress Stage of Herpes Simplex Virus Type-1 (HSV-1) Replication

Host Vesicle Fusion Proteins VAPB, Rab11b and Rab18 Contribute to HSV-1 Infectivity by Facilitating Egress through the Nuclear Membrane

Identification of novel integral membrane proteins of the nuclear envelope with potential disease links using subtractive proteomics

Immunohistochemistry on a panel of Emery-Dreifuss muscular dystrophy samples reveals nuclear envelope proteins as inconsistent markers for pathology.

In vitro activation of human herpesviruses 6 and 7 from latency

Inner nuclear membrane protein transport is mediated by multiple mechanisms.

Interactions of the chaperone Hsp104 with yeast Sup35 and mammalian PrP.

Involvement of the lamin rod domain in heterotypic lamin interactions important for nuclear organization

Isolation of a new herpesvirus from human CD4+ T cells

Isolation, Proteomic Analysis, and Microscopy Confirmation of the Liver Nuclear Envelope Proteome

LINC'ing form and function at the nuclear envelope.

Lamin A molecular compression and sliding as mechanisms behind nucleoskeleton elasticity

Lipids contribute to epigenetic control via chromatin structure and functions

Many mechanisms, one entrance: membrane protein translocation into the nucleus

Microinjection of Antibodies Targeting the Lamin A/C Histone-Binding Site Blocks Mitotic Entry and Reveals Separate Chromatin Interactions with HP1, CenpB and PML.

Mitotic post-translational modifications of histones promote chromatin compaction in vitro

MudPIT: A powerful proteomics tool for discovery

NET23/STING promotes chromatin compaction from the nuclear envelope

NETs and cell cycle regulation

Navigating the Nuclear Envelope: One or Multiple Transport Mechanisms for Integral Membrane Proteins?

Nuclear envelope influences on genome organization

Nuclear envelope: connecting structural genome organization to regulation of gene expression

Nuclear import of adenovirus DNA in vitro involves the nuclear protein import pathway and hsc70.

Nuclear membrane diversity: underlying tissue-specific pathologies in disease?

Nuclear membrane proteins with potential disease links found by subtractive proteomics

Nucleoplasmic signals promote directed transmembrane protein import simultaneously via multiple channels of nuclear pores

Nup50, a nucleoplasmically oriented nucleoporin with a role in nuclear protein export

Optimization of DamID for use in primary cultures of mouse hepatocytes

Organellar proteomics: the prizes and pitfalls of opening the nuclear envelope.

Organelle proteome variation among different cell types: lessons from nuclear membrane proteins

Proteins that associate with lamins: many faces, many functions.

Purification of Lamins and Soluble Fragments of NETs

Purification of Nuclei and Preparation of Nuclear Envelopes from Skeletal Muscle

Reduction of a 4q35-encoded nuclear envelope protein in muscle differentiation

Repo-Man/PP1 regulates heterochromatin formation in interphase.

Self-seeded fibers formed by Sup35, the protein determinant of [PSI+], a heritable prion-like factor of S. cerevisiae.

Several novel nuclear envelope transmembrane proteins identified in skeletal muscle have cytoskeletal associations

Single-point single-molecule FRAP distinguishes inner and outer nuclear membrane protein distribution

Spatial Genome Organization: From Development to Disease

Spatial Organization of the Nucleus Compartmentalizes and Regulates the Genome

Specific nuclear envelope transmembrane proteins can promote the location of chromosomes to and from the nuclear periphery.

Subcellular Fractionation and Proteomics of Nuclear Envelopes

Subunit interactions influence the biochemical and biological properties of Hsp104

System analysis shows distinct mechanisms and common principles of nuclear envelope protein dynamics

T-cell activation is required for efficient replication of human herpesvirus 6.

TMEM120A and B: Nuclear Envelope Transmembrane Proteins Important for Adipocyte Differentiation

Telomere elongation through hTERT immortalization leads to chromosome repositioning in control cells and genomic instability in Hutchinson‐Gilford progeria syndrome fibroblasts, expressing a novel SUN1 isoform

The ATPase activity of Hsp104, effects of environmental conditions and mutations.

The Application of DamID to Identify Peripheral Gene Sequences in Differentiated and Primary Cells.

The Kaposi's sarcoma-associated herpesvirus ORF57 protein: a pleurotropic regulator of gene expression

The NEMP family supports metazoan fertility and nuclear envelope stiffness

The Nuclear Envelope

The apparent absence of lamin B1 and emerin in many tissue nuclei is due to epitope masking