List of works - Luigi Leanza

Activation of guanine-β-D-arabinofuranoside and deoxyguanosine to triphosphates by a common pathway blocks T lymphoblasts at different checkpoints.

scientific article published on 11 July 2010

Biophysical characterization and expression analysis of Kv1.3 potassium channel in primary human leukemic B cells.

scientific article

Clofazimine, Psora-4 and PAP-1, inhibitors of the potassium channel Kv1.3, as a new and selective therapeutic strategy in chronic lymphocytic leukemia.

scientific article published on 21 February 2013

Correlation between potassium channel expression and sensitivity to drug-induced cell death in tumor cell lines

scientific article published on January 2014

Direct Pharmacological Targeting of a Mitochondrial Ion Channel Selectively Kills Tumor Cells In Vivo

scientific article

Early effects of the antineoplastic agent salinomycin on mitochondrial function.

scientific article published on 22 October 2015

Impact of intracellular ion channels on cancer development and progression

scientific article

Impaired Mitochondrial ATP Production Downregulates Wnt Signaling via ER Stress Induction

scientific article published on 01 August 2019

Induction of apoptosis in macrophages via Kv1.3 and Kv1.5 potassium channels.

scientific article

Inhibitors of mitochondrial Kv1.3 channels induce Bax/Bak-independent death of cancer cells

scientific article published on 11 April 2012

Intracellular ion channels and cancer

scientific article

Lipid-mediated modulation of intracellular ion channels and redox state: physio-pathological implications

scientific article

Metabolic interrelations within guanine deoxynucleotide pools for mitochondrial and nuclear DNA maintenance.

scientific article published on 16 April 2008

Mitochondrial Metabolism, Contact Sites and Cellular Calcium Signaling: Implications for Tumorigenesis

scientific article published on 10 September 2020

Mitochondrial apoptosis is induced by Alkoxy phenyl-1-propanone derivatives through PP2A-mediated dephosphorylation of Bad and Foxo3A in CLL

scientific article published on 23 October 2018

Mitochondrial ion channels as oncological targets

scientific article published on 27 January 2014

Mitochondrial potassium channels in cell death

scientific article

Novel Mitochondria-Targeted Furocoumarin Derivatives as Possible Anti-Cancer Agents.

scientific article

Pharmacological targeting of ion channels for cancer therapy: In vivo evidences

scientific article

Physiology of intracellular potassium channels: A unifying role as mediators of counterion fluxes?

scientific article published on 9 March 2016

Physiology of potassium channels in the inner membrane of mitochondria

scientific article

Regulation of Proliferation by a Mitochondrial Potassium Channel in Pancreatic Ductal Adenocarcinoma Cells

scientific article published on 29 September 2017

Single-point mutations of a lysine residue change function of Bax and Bcl-xL expressed in Bax- and Bak-less mouse embryonic fibroblasts: novel insights into the molecular mechanisms of Bax-induced apoptosis.

scientific article published on October 2010

Targeting Mitochondrial Ion Channels to Fight Cancer

scholarly article by Magdalena Bachmann published in July 2018

Targeting the Mitochondrial Potassium Channel Kv1.3 to Kill Cancer Cells: Drugs, Strategies, and New Perspectives

scientific article published on 02 August 2019

Targeting the Potassium Channel Kv1.3 Kills Glioblastoma Cells

scientific article published in September 2017

Thylakoid potassium channel is required for efficient photosynthesis in cyanobacteria

scientific article

Transglutaminase Type 2 regulates the Wnt/β-catenin pathway in vertebrates

scientific article published on 05 March 2021

Tumor-reducing effect of the clinically used drug clofazimine in a SCID mouse model of pancreatic ductal adenocarcinoma

scientific article published on 16 August 2016

List of works by Luigi Leanza

Activation of guanine-β-D-arabinofuranoside and deoxyguanosine to triphosphates by a common pathway blocks T lymphoblasts at different checkpoints.

Biophysical characterization and expression analysis of Kv1.3 potassium channel in primary human leukemic B cells.

Clofazimine, Psora-4 and PAP-1, inhibitors of the potassium channel Kv1.3, as a new and selective therapeutic strategy in chronic lymphocytic leukemia.

Correlation between potassium channel expression and sensitivity to drug-induced cell death in tumor cell lines

Direct Pharmacological Targeting of a Mitochondrial Ion Channel Selectively Kills Tumor Cells In Vivo

Early effects of the antineoplastic agent salinomycin on mitochondrial function.

Impact of intracellular ion channels on cancer development and progression

Impaired Mitochondrial ATP Production Downregulates Wnt Signaling via ER Stress Induction

Induction of apoptosis in macrophages via Kv1.3 and Kv1.5 potassium channels.

Inhibitors of mitochondrial Kv1.3 channels induce Bax/Bak-independent death of cancer cells

Intracellular ion channels and cancer

Lipid-mediated modulation of intracellular ion channels and redox state: physio-pathological implications

Metabolic interrelations within guanine deoxynucleotide pools for mitochondrial and nuclear DNA maintenance.

Mitochondrial Metabolism, Contact Sites and Cellular Calcium Signaling: Implications for Tumorigenesis

Mitochondrial apoptosis is induced by Alkoxy phenyl-1-propanone derivatives through PP2A-mediated dephosphorylation of Bad and Foxo3A in CLL

Mitochondrial ion channels as oncological targets

Mitochondrial potassium channels in cell death

Novel Mitochondria-Targeted Furocoumarin Derivatives as Possible Anti-Cancer Agents.

Pharmacological targeting of ion channels for cancer therapy: In vivo evidences

Physiology of intracellular potassium channels: A unifying role as mediators of counterion fluxes?

Physiology of potassium channels in the inner membrane of mitochondria

Regulation of Proliferation by a Mitochondrial Potassium Channel in Pancreatic Ductal Adenocarcinoma Cells

Single-point mutations of a lysine residue change function of Bax and Bcl-xL expressed in Bax- and Bak-less mouse embryonic fibroblasts: novel insights into the molecular mechanisms of Bax-induced apoptosis.

Targeting Mitochondrial Ion Channels to Fight Cancer

Targeting the Mitochondrial Potassium Channel Kv1.3 to Kill Cancer Cells: Drugs, Strategies, and New Perspectives

Targeting the Potassium Channel Kv1.3 Kills Glioblastoma Cells

Thylakoid potassium channel is required for efficient photosynthesis in cyanobacteria

Transglutaminase Type 2 regulates the Wnt/β-catenin pathway in vertebrates

Tumor-reducing effect of the clinically used drug clofazimine in a SCID mouse model of pancreatic ductal adenocarcinoma