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List of works by Jouni Hirvonen

A Caco-2 cell based screening method for compounds interacting with MRP2 efflux protein.

scientific article

A Versatile Carbonic Anhydrase IX Targeting Ligand-Functionalized Porous Silicon Nanoplatform for Dual Hypoxia Cancer Therapy and Imaging

scientific article published on 6 April 2017

A modification of the Hammett equation for predicting ionisation constants of p-vinyl phenols.

scientific article published in July 2005

A prospective cancer chemo-immunotherapy approach mediated by synergistic CD326 targeted porous silicon nanovectors

Active diffusion of nanoparticles of maternal origin within the embryonic brain

scientific article

Advanced Nanomedicines for the Treatment and Diagnosis of Myocardial Infarction and Heart Failure.

scientific article

Aerosolization, Drug Permeation and Cellular Interaction of Dry Powder Pulmonary Formulations of Corticosteroids with Hydroxypropyl-β-Cyclodextrin as a Solubilizer.

scientific article published on 7 September 2016

Amine modification of thermally carbonized porous silicon with silane coupling chemistry

scientific article published on 20 September 2012

Amine-modified hyaluronic acid-functionalized porous silicon nanoparticles for targeting breast cancer tumors

scientific article

Angiopep2-functionalized polymersomes for targeted doxorubicin delivery to glioblastoma cells

scientific article published on 30 July 2016

Antihyperglycemic potential of incretins orally delivered via nano and microsystems and subsequent glucoregulatory effects.

scientific article published on January 2014

Artificially cloaked viral nanovaccine for cancer immunotherapy

scientific article published on 17 December 2019

Augmented cellular trafficking and endosomal escape of porous silicon nanoparticles via zwitterionic bilayer polymer surface engineering.

scientific article

Biocompatibility of thermally hydrocarbonized porous silicon nanoparticles and their biodistribution in rats

scientific article published on 01 June 2010

Biohybrid Vaccines for Improved Treatment of Aggressive Melanoma with Checkpoint Inhibitor

scientific article published on 17 May 2019

Biomimetic Engineering Using Cancer Cell Membranes for Designing Compartmentalized Nanoreactors with Organelle-Like Functions.

scientific article published on 23 January 2017

Bridging the Knowledge of Different Worlds to Understand the Big Picture of Cancer Nanomedicines.

scientific article published on June 2017

Brinzolamide nanocrystal formulations for ophthalmic delivery: reduction of elevated intraocular pressure in vivo.

scientific article published on 26 March 2014

Caco-2 cell monolayers as a tool to study simultaneous phase II metabolism and metabolite efflux of indomethacin, paracetamol and 1-naphthol.

scientific article

Cardiac Actions of a Small Molecule Inhibitor Targeting GATA4-NKX2-5 Interaction.

scientific article

Cell-polymer interactions of fluorescent polystyrene latex particles coated with thermosensitive poly(N-isopropylacrylamide) and poly(N-vinylcaprolactam) or grafted with poly(ethylene oxide)-macromonomer.

scientific article

Cellular interactions of surface modified nanoporous silicon particles ⬇️

scientific article published on April 16, 2012

Chitosan-modified porous silicon microparticles for enhanced permeability of insulin across intestinal cell monolayers

scientific article published on 17 May 2014

Co-delivery of a hydrophobic small molecule and a hydrophilic peptide by porous silicon nanoparticles.

scientific article published on 10 June 2013

Coated particle assemblies for the concomitant pulmonary administration of budesonide and salbutamol sulphate.

scientific article published on 28 November 2012

Comparison of liposomal drug formulations for transdermal iontophoretic drug delivery

scientific article published on 15 June 2017

Comparison of mesoporous silicon and non-ordered mesoporous silica materials as drug carriers for itraconazole

scientific article published on 12 May 2011

Competence-Based Pharmacy Education in the University of Helsinki.

scientific article published on June 2017

Conductive vancomycin-loaded mesoporous silica polypyrrole-based scaffolds for bone regeneration.

scientific article

Confinement effects on drugs in thermally hydrocarbonized porous silicon

scientific article published on 20 February 2014

Conjugation of peptides to antisense interleukin-6 via click chemistry.

scientific article published in April 2014

Controlled transdermal delivery of leuprorelin by pulsed iontophoresis and ion-exchange fiber

scientific article published on 27 August 2014

Copper-free azide-alkyne cycloaddition of targeting peptides to porous silicon nanoparticles for intracellular drug uptake.

scientific article published on 7 November 2013

Core/Shell Nanocomposites Produced by Superfast Sequential Microfluidic Nanoprecipitation.

scientific article published on 6 January 2017

Current developments and applications of microfluidic technology toward clinical translation of nanomedicines.

scientific article published on 8 August 2017

Cyclodextrin-Modified Porous Silicon Nanoparticles for Efficient Sustained Drug Delivery and Proliferation Inhibition of Breast Cancer Cells

scientific article published on 6 October 2015

Defining new criteria for selection of cell-based intestinal models using publicly available databases.

scientific article

Delivery and stability of LHRH and Nafarelin in human skin: the effect of constant/pulsed iontophoresis.

scientific article published in February 2004

Delivery of therapeutics with nanoparticles: what's new in cancer immunotherapy?

scientific article published on 29 July 2016

Diatom silica microparticles for sustained release and permeation enhancement following oral delivery of prednisone and mesalamine.

scientific article

Dissolution study of nanocrystal powders of a poorly soluble drug by UV imaging and channel flow methods

scientific article published on 30 August 2013

Does the Subject Content of the Pharmacy Degree Course Influence the Community Pharmacist's Views on Competencies for Practice?

scientific article published on September 2015

Drug adsorption in human skin: a streaming potential study.

scientific article published in December 2003

Drug delivery formulations of ordered and nonordered mesoporous silica: comparison of three drug loading methods

scientific article published on 24 April 2011

Drug nanocrystals - Versatile option for formulation of poorly soluble materials

scientific article published on 17 December 2017

Drug permeation across intestinal epithelial cells using porous silicon nanoparticles.

scientific article

Drug permeation and cellular interaction of amino acid-coated drug combination powders for pulmonary delivery.

scientific article published on 28 March 2016

Drug release characteristics of physically cross-linked thermosensitive poly(N-vinylcaprolactam) hydrogel particles.

scientific article

Drug-Loaded Multifunctional Nanoparticles Targeted to the Endocardial Layer of the Injured Heart Modulate Hypertrophic Signaling

scientific article published on 17 July 2017

Dual chitosan/albumin-coated alginate/dextran sulfate nanoparticles for enhanced oral delivery of insulin

scientific article published on 10 April 2016

Dual-drug delivery by porous silicon nanoparticles for improved cellular uptake, sustained release, and combination therapy.

scientific article

Dual-peptide functionalized acetalated dextran-based nanoparticles for sequential targeting of macrophages during myocardial infarction

scientific article published on 13 January 2020

Effect of diffusion potential, osmosis and ion-exchange on transdermal drug delivery: theory and experiments ⬇️

scientific article published on December 4, 1998

Effect of nanoprecipitation on the physicochemical properties of low molecular weight poly(L-lactic acid) nanoparticles loaded with salbutamol sulphate and beclomethasone dipropionate.

scientific article published in May 2005

Effects of cell differentiation and assay conditions on the UDP-glucuronosyltransferase activity in Caco-2 cells

scientific article published on 23 November 2010

Electrospraying, spray drying and related techniques for production and formulation of drug nanoparticles.

scientific article published on June 2010

Engineered Multifunctional Albumin-Decorated Porous Silicon Nanoparticles for FcRn Translocation of Insulin

scientific article published on 31 May 2018

Engineered antibody-functionalized porous silicon nanoparticles for therapeutic targeting of pro-survival pathway in endogenous neuroblasts after stroke

scientific article published on 18 October 2019

Enhanced in vitro permeation of furosemide loaded into thermally carbonized mesoporous silicon (TCPSi) microparticles

scientific article published on 01 December 2006

Equilibrium drug solubility measurements in 96-well plates reveal similar drug solubilities in phosphate buffer pH 6.8 and human intestinal fluid

scientific article published on 10 December 2010

Evaluation of cocktail approach to standardise Caco-2 permeability experiments.

scientific article published on 30 June 2006

Evaluation of drug interactions with nanofibrillar cellulose

scientific article published on 15 June 2013

Evaluation of mesoporous TCPSi, MCM-41, SBA-15, and TUD-1 materials as API carriers for oral drug delivery

scientific article published on 01 August 2007

Evaluation of the physicochemical and biopharmaceutical properties of fluoro-indomethacin

scientific article published on 01 January 2013

Experimental verification of the mechanistic model for transdermal transport including iontophoresis.

scientific article published in December 1998

Expression and characterization of recombinant human UDP-glucuronosyltransferases (UGTs). UGT1A9 is more resistant to detergent inhibition than other UGTs and was purified as an active dimeric enzyme.

scientific article published on 14 November 2002

Fabrication and Characterization of Drug-Loaded Conductive Poly(glycerol sebacate)/Nanoparticle-Based Composite Patch for Myocardial Infarction Applications

scientific article published on 03 February 2020

Fabrication of a multifunctional nano-in-micro drug delivery platform by microfluidic templated encapsulation of porous silicon in polymer matrix.

scientific article

Fluorescence-based high-throughput screening assay for drug interactions with UGT1A6

scientific article published on 25 March 2011

Functional hydrophobin-coating of thermally hydrocarbonized porous silicon microparticles

scientific article published on 23 August 2011

Functionalization of alkyne-terminated thermally hydrocarbonized porous silicon nanoparticles with targeting peptides and antifouling polymers: effect on the human plasma protein adsorption

scientific article published on 13 January 2015

Functionalization of carboxylated lignin nanoparticles for targeted and pH-responsive delivery of anticancer drugs

scientific article published on 29 September 2017

Hierarchical structured and programmed vehicles deliver drugs locally to inflamed sites of intestine

scientific article published on 19 September 2018

High-Generation Amphiphilic Janus-Dendrimers as Stabilizing Agents for Drug Suspensions

scientific article published on 12 September 2018

Hospital and Community Pharmacists' Perceptions of Which Competences Are Important for Their Practice.

scientific article published on 15 June 2016

How Do European Pharmacy Students Rank Competences for Practice?

scientific article published on 26 January 2016

Impact of Pore Size and Surface Chemistry of Porous Silicon Particles and Structure of Phospholipids on Their Interactions

scientific article published on 14 June 2018

In situ measurement of solvent-mediated phase transformations during dissolution testing

scientific article published on 01 December 2006

In vitro assessment of biopolymer-modified porous silicon microparticles for wound healing applications

scientific article published on 8 October 2014

In vitro cytotoxicity of porous silicon microparticles: effect of the particle concentration, surface chemistry and size

scientific article published on 29 December 2009

In vitro toxicity and permeation of cyclodextrins in Calu-3 cells.

scientific article published on 17 November 2007

In vivo dual-delivery of glucagon like peptide-1 (GLP-1) and dipeptidyl peptidase-4 (DPP4) inhibitor through composites prepared by microfluidics for diabetes therapy.

scientific article published on 6 May 2016

In vivo evaluation of porous silicon and porous silicon solid lipid nanocomposites for passive targeting and imaging.

scientific article

Influence of Surface Chemistry on Ibuprofen Adsorption and Confinement in Mesoporous Silicon Microparticles

scientific article published on 30 November 2016

Inhibition of influenza A virus infection in vitro by saliphenylhalamide-loaded porous silicon nanoparticles.

scientific article published on August 2013

Inhibitory activity of the isoflavone biochanin A on intracellular bacteria of genus Chlamydia and initial development of a buccal formulation

scientific article

Intact nanoparticulate indomethacin in fast-dissolving carrier particles by combined wet milling and aerosol flow reactor methods

scientific article published on 04 May 2011

Interaction studies between indomethacin nanocrystals and PEO/PPO copolymer stabilizers

scientific article published on 22 August 2014

Interactions with other human UDP-glucuronosyltransferases attenuate the consequences of the Y485D mutation on the activity and substrate affinity of UGT1A6.

scientific article published in February 2007

Intracellular responsive dual delivery by endosomolytic polyplexes carrying DNA anchored porous silicon nanoparticles.

scientific article

Intravenous delivery of hydrophobin-functionalized porous silicon nanoparticles: stability, plasma protein adsorption and biodistribution

scientific article published on February 2012

In vitro and in vivo assessment of heart-homing porous silicon nanoparticles

scientific article published on 11 April 2016

In vitro evaluation of biodegradable lignin-based nanoparticles for drug delivery and enhanced antiproliferation effect in cancer cells

scientific article

In vivo biocompatibility of porous silicon biomaterials for drug delivery to the heart.

scientific article published on 28 June 2014

Ion-exchange and iontophoresis-controlled delivery of apomorphine.

scientific article

Ion-exchange fibers and drugs: a novel device for the screening of iontophoretic systems.

scientific article

Ion-exchange fibers and drugs: a transient study

scientific article published on 01 September 2003

Kinetic characterization of the 1A subfamily of recombinant human UDP-glucuronosyltransferases.

scientific article published on 31 March 2005

Mechanistic evaluation of factors affecting compound loading into ion-exchange fibers.

scientific article published on 6 May 2007

Mesoporous materials and nanocrystals for enhancing the dissolution behavior of poorly water-soluble drugs.

scientific article published on January 2013

Mesoporous silica material TUD-1 as a drug delivery system

scientific article

Mesoporous silicon in drug delivery applications.

scientific article published on February 2008

Microfluidic Assembly of a Multifunctional Tailorable Composite System Designed for Site Specific Combined Oral Delivery of Peptide Drugs.

scientific article published on 5 August 2015

Microfluidic Nanoassembly of Bioengineered Chitosan-Modified FcRn-Targeted Porous Silicon Nanoparticles @ Hypromellose Acetate Succinate for Oral Delivery of Antidiabetic Peptides

scientific article published on 17 December 2018

Microfluidic assembly of a nano-in-micro dual drug delivery platform composed of halloysite nanotubes and a pH-responsive polymer for colon cancer therapy

scientific article published in November 2016

Microfluidic assembly of monodisperse multistage pH-responsive polymer/porous silicon composites for precisely controlled multi-drug delivery

scientific article published on 25 February 2014

Microfluidic assembly of multistage porous silicon-lipid vesicles for controlled drug release

scientific article

Microfluidic assisted one-step fabrication of porous silicon@acetalated dextran nanocomposites for precisely controlled combination chemotherapy

scientific article

Microfluidic templated mesoporous silicon-solid lipid microcomposites for sustained drug delivery

scientific article published on 13 November 2013

Microfluidics for Production of Particles: Mechanism, Methodology, and Applications

scientific article published on 08 November 2019

Microfluidics platform for glass capillaries and its application in droplet and nanoparticle fabrication.

scientific article

Microparticles to enhance delivery of drugs and growth factors into wound sites.

scientific article published on October 2016

Modular synthesis of self-assembling Janus-dendrimers and facile preparation of drug-loaded dendrimersomes

scientific article published on 17 May 2017

Multifunctional Nanotube-Mucoadhesive Poly(methyl vinyl ether-co-maleic acid)@Hydroxypropyl Methylcellulose Acetate Succinate Composite for Site-Specific Oral Drug Delivery

scientific article

Multifunctional hydrophobin: toward functional coatings for drug nanoparticles.

scientific article published in March 2010

Multifunctional porous silicon nanoparticles for cancer theranostics.

scientific article

Multistage pH-responsive mucoadhesive nanocarriers prepared by aerosol flow reactor technology: A controlled dual protein-drug delivery system

scientific article published on 26 July 2015

Multistaged Nanovaccines Based on Porous Silicon@Acetalated Dextran@Cancer Cell Membrane for Cancer Immunotherapy.

scientific article published on 23 December 2016

Nanocrystal-based per-oral itraconazole delivery: superior in vitro dissolution enhancement versus Sporanox® is not realized in in vivo drug absorption

scientific article published on 22 February 2014

Nanofibrillar cellulose films for controlled drug delivery.

scientific article published on 30 June 2012

Nanostructured porous silicon materials: potential candidates for improving drug delivery

scientific article published on 01 September 2012

Nanosuspensions of poorly soluble drugs: preparation and development by wet milling

scientific article published on 31 March 2011

Neonatal Fc receptor-targeted lignin-encapsulated porous silicon nanoparticles for enhanced cellular interactions and insulin permeation across the intestinal epithelium

scientific article published on 10 August 2021

New times, new trends for ethionamide: In vitro evaluation of drug-loaded thermally carbonized porous silicon microparticles.

scientific article

Nutlin-3a and Cytokine Co-loaded Spermine-Modified Acetalated Dextran Nanoparticles for Cancer Chemo-Immunotherapy

Oral hypoglycaemic effect of GLP-1 and DPP4 inhibitor based nanocomposites in a diabetic animal model

article

Pharmaceutical nanocrystals by nanomilling: critical process parameters, particle fracturing and stabilization methods

scientific article published on November 1, 2010

Pharmacy Mentors' Views of Practical Training

Pharmacy Practice and Education in Finland

scientific article published on 23 February 2019

Physicochemical stability of high indomethacin payload ordered mesoporous silica MCM-41 and SBA-15 microparticles

scientific article published on 07 July 2011

Platelet Lysate-Modified Porous Silicon Microparticles for Enhanced Cell Proliferation in Wound Healing Applications.

scientific article published on 24 December 2015

Poly(methyl vinyl ether-alt-maleic acid)-functionalized porous silicon nanoparticles for enhanced stability and cellular internalization

scientific article published on 3 February 2014

Porous silicon nanoparticles for nanomedicine: preparation and biomedical applications.

scientific article published on April 2014

Preparation and Characterization of Dentin Phosphophoryn-Derived Peptide-Functionalized Lignin Nanoparticles for Enhanced Cellular Uptake

scientific article published on 06 May 2019

Production of pure drug nanocrystals and nano co-crystals by confinement methods

scientific article published on 05 May 2018

Quercetin-Based Modified Porous Silicon Nanoparticles for Enhanced Inhibition of Doxorubicin-Resistant Cancer Cells

scientific article published on 12 December 2016

Rate and extent of ion-exchange process: the effect of physico-chemical characteristics of salicylate anions.

scientific article published in September 2003

Receptor-Mediated Surface Charge Inversion Platform Based on Porous Silicon Nanoparticles for Efficient Cancer Cell Recognition and Combination Therapy.

scientific article published on March 2017

SVM classification and CoMSIA modeling of UGT1A6 interacting molecules.

scientific article published on 18 March 2014

Safety and toxicity concerns of orally delivered nanoparticles as drug carriers

scientific article published on 13 December 2014

Self-Assembly of Amphiphilic Janus Dendrimers into Mechanically Robust Supramolecular Hydrogels for Sustained Drug Release

scientific article published on 01 July 2015

Solid formulations by a nanocrystal approach: critical process parameters regarding scale-ability of nanocrystals for tableting applications

scientific article published on 05 March 2015

Spray-dried cellulose nanofibers as novel tablet excipient.

scientific article

Spray-dried nanofibrillar cellulose microparticles for sustained drug release.

scientific article published on 24 March 2012

Stabilizing Agents for Drug Nanocrystals: Effect on Bioavailability

scientific article

Surface chemistry dependent immunostimulative potential of porous silicon nanoplatforms

scientific article published on 12 August 2014

Surface modification of acetaminophen particles by atomic layer deposition.

scientific article published on 18 April 2017

Systematic in vitro and in vivo study on porous silicon to improve the oral bioavailability of celecoxib

scientific article published on 21 February 2015

Tablet preformulations of indomethacin-loaded mesoporous silicon microparticles

scientific article published on 28 October 2011

Tailoring Porous Silicon for Biomedical Applications: From Drug Delivery to Cancer Immunotherapy.

scientific article published on 13 March 2018

Targeted Cancer Therapy: pH-Switch Nanoprecipitation of Polymeric Nanoparticles for Multimodal Cancer Targeting and Intracellular Triggered Delivery of Doxorubicin (Adv. Healthcare Mater. 15/2016).

scientific article published in August 2016

Targeted Reinforcement of Macrophage Reprogramming Toward M2 Polarization by IL-4-Loaded Hyaluronic Acid Particles

scientific article published on 27 December 2018

The Behavior of Sorbitan Surfactants at the Water-Oil Interface: Straight-Chained Hydrocarbons from Pentane to Dodecane as an Oil Phase

scientific article published on 01 August 2001

The PHAR-QA Project: Competency Framework for Pharmacy Practice-First Steps, the Results of the European Network Delphi Round 1.

scientific article published on 17 November 2015

The Second Round of the PHAR-QA Survey of Competences for Pharmacy Practice

scientific article published on 21 September 2016

The Significance of Practical Training in Linking Theoretical Studies with Practice

The effect of valence on the ion-exchange process: theoretical and experimental aspects on compound binding/release

scientific article published on 01 January 2007

The impact of nanoparticles on the mucosal translocation and transport of GLP-1 across the intestinal epithelium

scientific article published on 07 August 2014

The interactions between the N-terminal and C-terminal domains of the human UDP-glucuronosyltransferases are partly isoform-specific, and may involve both monomers.

scientific article published in December 2004

The mucoadhesive and gastroretentive properties of hydrophobin-coated porous silicon nanoparticle oral drug delivery systems

scientific article published on 29 January 2012

The versatile biomedical applications of bismuth-based nanoparticles and composites: therapeutic, diagnostic, biosensing, and regenerative properties

scientific article published on 30 January 2020

Thiolation and Cell-Penetrating Peptide Surface Functionalization of Porous Silicon Nanoparticles for Oral Delivery of Insulin

Towards more reliable automated multi-dose dispensing: retrospective follow-up study on medication dose errors and product defects ⬇️

scientific article published on March 30, 2012

Transdermal iontophoresis of flufenamic acid loaded PLGA nanoparticles.

scientific article published on 27 April 2016

Tumour homing peptide-functionalized porous silicon nanovectors for cancer therapy.

scientific article published on 3 September 2013

Use of conventional surfactant media as surrogates for FaSSIF in simulating in vivo dissolution of BCS class II drugs ⬇️

scientific article published on February 15, 2011

What is a Pharmacist: Opinions of Pharmacy Department Academics and Community Pharmacists on Competences Required for Pharmacy Practice

scientific article published on February 2016

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pH-Switch Nanoprecipitation of Polymeric Nanoparticles for Multimodal Cancer Targeting and Intracellular Triggered Delivery of Doxorubicin.

scientific article

¹⁸F-labeled modified porous silicon particles for investigation of drug delivery carrier distribution in vivo with positron emission tomography

scientific article published on 07 September 2011

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