List of works - Mary E Wlodek

Adolescence and the next generation

scientific article published in February 2018

Adrenal, metabolic and cardio-renal dysfunction develops after pregnancy in rats born small or stressed by physiological measurements during pregnancy.

scientific article published on 12 June 2016

Angiotensin receptor blockade in juvenile male rat offspring: Implications for long-term cardio-renal health

scientific article published on 02 June 2018

Bladder contractions and micturition in fetal sheep: their relation to behavioral states

scientific article published on 01 December 1989

Brain allopregnanolone in the fetal and postnatal rat in response to uteroplacental insufficiency.

scientific article published on 13 June 2008

Calcium supplementation does not rescue the programmed adult bone deficits associated with perinatal growth restriction.

scientific article published on 9 September 2010

Cardio-renal and metabolic adaptations during pregnancy in female rats born small: implications for maternal health and second generation fetal growth

scientific article

Cardiovascular and renal disease in the adolescent guinea pig after chronic placental insufficiency.

scientific article published in September 2004

Cross-fostering and improved lactation ameliorates deficits in endocrine pancreatic morphology in growth-restricted adult male rat offspring.

scientific article published in August 2010

DNA Methyltransferase 1 Controls Nephron Progenitor Cell Renewal and Differentiation

scientific article published on 05 December 2018

Decreased expression of the rat myometrial relaxin receptor (RXFP1) in late pregnancy is partially mediated by the presence of the conceptus

scientific article published on 4 August 2010

Decreased urine production in the near-term fetal lamb after maternal ethanol infusion

scientific article published on 01 May 1987

Delayed myelination and neurodevelopment in male seizure-prone versus seizure-resistant rats.

scientific article published on 28 January 2018

Developmental programming of bone deficits in growth-restricted offspring

scientific article published on 11 March 2014

Developmental programming: variations in early growth and adult disease

scientific article

Differences in white matter structure between seizure prone (FAST) and seizure resistant (SLOW) rat strains

scientific article

Does perinatal omega-3 polyunsaturated fatty acid deficiency increase appetite signaling?

scientific article published in November 2004

Effect of high oxygen on placental function in short-term explant cultures

scientific article published on 21 February 2007

Effect of nuclear factor-kappa B inhibitors and peroxisome proliferator-activated receptor-gamma ligands on PTHrP release from human fetal membranes.

scientific article

Effect of pregnancy for females born small on later life metabolic disease risk

scientific article

Effects of inhibition of prostaglandin synthesis on flow and composition of fetal urine, lung liquid, and swallowed fluid in sheep

scientific article published on 01 January 1994

Effects of prolonged hypoxemia on fetal renal function and amniotic fluid volume in sheep

scientific article published on 01 February 1997

Effects of prostaglandin E2 on renal function and lung liquid dynamics in foetal sheep

scientific article published on 01 October 1998

Effects of uteroplacental insufficiency and reducing litter size on maternal mammary function and postnatal offspring growth.

scientific article published on 12 December 2007

Effects of uteroplacental restriction on the relaxin-family receptors, Lgr7 and Lgr8, in the uterus of late pregnant rats

scientific article published on 01 January 2007

Embryo transfer cannot delineate between the maternal pregnancy environment and germ line effects in the transgenerational transmission of disease in rats

scientific article

Endocrine responses of fetal sheep to prolonged hypoxemia with and without acidemia: relation to urine production

scientific article published on 01 May 1995

Endurance training in early life results in long-term programming of heart mass in rats

scientific article published on February 2016

Evaluation of right heart function in a rat model using modified echocardiographic views

scientific article published on 31 October 2017

Exercise as an intervention to improve metabolic outcomes after intrauterine growth restriction

scientific article

Exercise early in life in rats born small does not normalize reductions in skeletal muscle PGC-1α in adulthood

article

Exercise initiated during pregnancy in rats born growth restricted alters placental mTOR and nutrient transporter expression

scientific article published on 01 March 2019

Experimental and Human Evidence for Lipocalin-2 (Neutrophil Gelatinase-Associated Lipocalin [NGAL]) in the Development of Cardiac Hypertrophy and heart failure

scientific article published on 14 June 2017

Expression and localisation of GLUT1 and GLUT12 glucose transporters in the pregnant and lactating rat mammary gland.

scientific article published on 15 November 2002

Fathers that are born small program alterations in the next-generation preimplantation rat embryos.

scientific article published on 25 March 2015

Fetal growth restriction shortens cardiac telomere length, but this is attenuated by exercise in early life

scientific article published on 07 September 2018

Fetal versus maternal determinants of the reduced fetal and placental growth in spontaneously hypertensive rats

scientific article published on 01 January 2000

Fetal-maternal fluid and electrolyte relations during chronic fetal urine loss in sheep

scientific article published on 01 October 1992

First Report Of Active Renin In Rat Amniotic Fluid

scientific article published on 01 August 2000

Growth restriction alters adult spatial memory and sensorimotor gating in a sex-specific manner.

scientific article

Growth restriction before and after birth increases kinase signaling pathways in the adult rat heart

scientific article published on 01 December 2010

Growth restriction before or after birth reduces nephron number and increases blood pressure in male rats

scientific article published on 23 April 2008

Growth restriction in the rat alters expression of cardiac JAK/STAT genes in a sex-specific manner.

scientific article published in August 2014

Identification of the Alzheimer's disease amyloid precursor protein (APP) and its homologue APLP2 as essential modulators of glucose and insulin homeostasis and growth

scientific article

Impact of Intrauterine Growth Restriction on the Capillarization of the Early Postnatal Rat Heart

scientific article published on 07 January 2019

Impact of low dose prenatal ethanol exposure on glucose homeostasis in Sprague-Dawley rats aged up to eight months

scientific article

Improved lactational nutrition and postnatal growth ameliorates impairment of glucose tolerance by uteroplacental insufficiency in male rat offspring.

scientific article

Insulin-like Growth Factors and Foetal Programming—A Workshop Report

scientific article published on 01 April 2003

Intrauterine Growth Restriction Alters the Postnatal Development of the Rat Cerebellum

scientific article published on 28 April 2017

Intrauterine expression of parathyroid hormone-related protein in normal and pre-eclamptic pregnancies

scientific article published on 01 November 1998

Lack of evidence for a role for either the in utero or suckling periods in the exaggerated salt preference of the spontaneously hypertensive rat

scientific article published on 07 October 2005

Leptin in pregnancy and development: a contributor to adulthood disease?

scientific article

Localization of relaxin receptors in arteries and veins, and region-specific increases in compliance and bradykinin-mediated relaxation after in vivo serelaxin treatment

scientific article published on 13 September 2013

Locations and molecular forms of gastrin-releasing peptide-like immunoreactive entities in ovine pregnancy

scientific article published on 01 January 1996

Long-term alteration in maternal blood pressure and renal function after pregnancy in normal and growth-restricted rats

scientific article published on 14 May 2012

Low female birth weight and advanced maternal age programme alterations in next-generation blastocyst development

scientific article published on 9 February 2015

Maternal adaptations and inheritance in the transgenerational programming of adult disease

scientific article published on 18 April 2012

Maternal alcohol intake around the time of conception causes glucose intolerance and insulin insensitivity in rat offspring, which is exacerbated by a postnatal high-fat diet

scientific article

Maternal exercise and growth restriction in rats alters placental angiogenic factors and blood space area in a sex-specific manner

scientific article published on 15 December 2018

Maternal exercise in rats upregulates the placental insulin-like growth factor system with diet- and sex-specific responses: minimal effects in mothers born growth restricted

scientific article published on 26 July 2018

Maternal growth restriction and stress exposure in rats differentially alters expression of components of the placental glucocorticoid barrier and nutrient transporters.

scientific article published on 15 September 2017

Maternal obesity in females born small: Pregnancy complications and offspring disease risk

scientific article published on 14 July 2015

Maternal stress does not exacerbate long-term bone deficits in female rats born growth restricted, with differential effects on offspring bone health

scientific article

Moderate prenatal ethanol exposure in the rat promotes kidney cell apoptosis, nephron deficits, and sex-specific kidney dysfunction in adult offspring

scientific article published on 27 January 2020

Normal Lactational Environment Restores Nephron Endowment and Prevents Hypertension after Placental Restriction in the Rat

scientific article published on 18 April 2007

Normal lactational environment restores cardiomyocyte number after uteroplacental insufficiency: implications for the preterm neonate

scientific article

Normal mammary gland growth and lactation capacity in pregnant relaxin-deficient mice

scientific article published in January 2009

Parathyroid hormone(1-34) and parathyroid hormone-related protein(1-34) stimulate calcium release from human syncytiotrophoblast basal membranes via a common receptor

scientific article published on 01 September 2000

Parathyroid hormone-related protein (PTHrP) concentrations in human amniotic fluid during gestation and at the time of labour

article

Parathyroid hormone-related protein (PTHrP) mRNA splicing and parathyroid hormone/PTHrP receptor mRNA expression in human placenta and fetal membranes

scientific article published on 01 October 1998

Parathyroid hormone-related protein(1-34) in gestational fluids and release from human gestational tissues

scientific article

Periconceptional alcohol consumption causes fetal growth restriction and increases glycogen accumulation in the late gestation rat placenta.

scientific article

Periconceptional alcohol exposure causes female-specific perturbations to trophoblast differentiation and placental formation in the rat

scientific article published on 10 June 2019

Periconceptional ethanol exposure induces a sex specific diuresis and increase in AQP2 and AVPR2 in the kidneys of aged rat offspring

scientific article published on 01 November 2019

Physiological skeletal gains and losses in rat mothers during pregnancy and lactation are not observed following uteroplacental insufficiency

scientific article published on 01 March 2014

Plasma adrenocorticotropic hormone and cortisol and adrenal blood flow during sustained hypoxemia in fetal sheep

scientific article published on 01 December 1986

Possible role of uterine contractions in the short-term fluctuations of plasma ACTH concentration in fetal sheep

scientific article published on 01 August 1985

Pregnancy in aged rats that were born small: cardiorenal and metabolic adaptations and second-generation fetal growth

scientific article published on 6 July 2012

Pregnant growth restricted female rats have bone gains during late gestation which contributes to second generation adolescent and adult offspring having normal bone health.

scientific article published on 3 February 2015

Preterm fetal growth restriction is associated with increased parathyroid hormone-related protein expression in the fetal membranes

scientific article published on 01 September 2000

Progesterone withdrawal, and not increased circulating relaxin, mediates the decrease in myometrial relaxin receptor (RXFP1) expression in late gestation in rats

scientific journal article

Programming of maternal and offspring disease: impact of growth restriction, fetal sex and transmission across generations

scientific article published on 11 March 2016

Puberty onset is delayed following uteroplacental insufficiency and occurs earlier with improved lactation and growth for pups born small.

scientific article published on 11 August 2015

Publisher Correction: Adolescence and the next generation.

scientific article published on 2 May 2018

Reduced fetal, placental, and amniotic fluid PTHrP in the growth-restricted spontaneously hypertensive rat

scientific article published on 01 July 2000

Reduced intestinal epithelial cell brush border membrane calcium transport in spontaneously hypertensive rats

scientific article published on 01 June 1999

Reducing Pup Litter Size Alters Early Postnatal Calcium Homeostasis and Programs Adverse Adult Cardiovascular and Bone Health in Male Rats

article

Relation between fetal arterial PO2 and oxytocin-induced uterine contractions in pregnant sheep

scientific article published on 01 October 1984

Relative contribution of the prenatal versus postnatal period on development of hypertension and growth rate of the spontaneously hypertensive rat.

scientific article published in January 2006

Relaxin mediates uterine artery compliance during pregnancy and increases uterine blood flow

scientific article

Reproduction, development, and the early origins of adult disease

article

Respiratory modulation of sympathetic nerve activity is enhanced in male rat offspring following uteroplacental insufficiency

scientific article published on 16 November 2015

Sex-Specific Metabolic Outcomes in Offspring of Female Rats Born Small or Exposed to Stress During Pregnancy.

scientific article published on 29 August 2016

Short-term exercise training early in life restores deficits in pancreatic β-cell mass associated with growth restriction in adult male rats

article

Source of inhibin in ovine fetal plasma and amniotic fluid during late gestation: half-life of fetal inhibin

scientific article published on 01 August 1997

Stage of perinatal development regulates skeletal muscle mitochondrial biogenesis and myogenic regulatory factor genes with little impact of growth restriction or cross-fostering

scientific article published in February 2012

Sustained cardiac programming by short-term juvenile exercise training in male rats.

scientific article

Swallowing and urine flow responses of ovine fetuses to 24 h of hypoxia

scientific article published on 01 April 1994

Swallowing of lung liquid and amniotic fluid by the ovine fetus under normoxic and hypoxic conditions

scientific article published on 01 September 1994

The effect of low-to-moderate-dose ethanol consumption on rat mammary gland structure and function and early postnatal growth of offspring

scientific article published on 20 March 2013

The effects of hypoxemia with progressive acidemia on fetal renal function in sheep

scientific article published on 01 December 1989

The effects of periconceptional maternal alcohol intake and a postnatal high-fat diet on obesity and liver disease in male and female rat offspring

scientific article published on 31 October 2017

The effects of twenty-four hours of reduced uterine blood flow on fetal fluid balance in sheep

scientific article published on 01 May 1994

The expression of parathyroid hormone-related protein mRNA and immunoreactive protein in human amnion and choriodecidua is increased at term compared with preterm gestation

scientific article published on 01 July 1997

The role of fetal urinary excretion in the transfer of ethanol into amniotic fluid after maternal administration of ethanol to the near-term pregnant ewe

scientific article published on 01 June 1987

The role of maternal nutrition, metabolic function and the placenta in developmental programming of renal dysfunction.

scientific article published on 16 October 2015

The spontaneously hypertensive rat fetus, not the mother, is responsible for the reduced amniotic fluid PTHrP concentrations and growth restriction

scientific article published on 01 August 2001

The transgenerational effect of maternal and paternal F1 low birth weight on bone health of second and third generation offspring.

scientific article published on 10 April 2018

Transgenerational left ventricular hypertrophy and hypertension in offspring after uteroplacental insufficiency in male rats

scientific article published on 01 November 2014

Transgenerational programming of fetal nephron deficits and sex-specific adult hypertension in rats

scientific article published in August 2014

Transgenerational programming of nephron deficits and hypertension

scientific article published on 07 June 2018

Treadmill Exercise before and during Pregnancy Improves Bone Deficits in Pregnant Growth Restricted Rats without the Exacerbated Effects of High Fat Diet

scientific article published on 30 May 2019

Urethral and urachal urine output to the amniotic and allantoic sacs in fetal sheep

scientific article published on 01 August 1988

Uteroplacental insufficiency alters the mammary gland response to lactogenic hormones in vitro.

scientific article published in January 2008

Uteroplacental insufficiency and lactational environment separately influence arterial stiffness and vascular function in adult male rats

scientific article published on 25 June 2012

Uteroplacental insufficiency and reducing litter size alters skeletal muscle mitochondrial biogenesis in a sex-specific manner in the adult rat.

scientific article published on 4 March 2008

Uteroplacental insufficiency causes a nephron deficit, modest renal insufficiency but no hypertension with ageing in female rats

scientific article

Uteroplacental insufficiency in rats induces renal apoptosis and delays nephrogenesis completion.

scientific article published on 19 October 2017

Uteroplacental insufficiency leads to hypertension, but not glucose intolerance or impaired skeletal muscle mitochondrial biogenesis, in 12-month-old rats

scientific article

Uteroplacental insufficiency programmes vascular dysfunction in non-pregnant rats: compensatory adaptations in pregnancy.

scientific article published on 14 May 2012

Uteroplacental insufficiency programs regional vascular dysfunction and alters arterial stiffness in female offspring.

scientific article published on 19 April 2010

Uteroplacental insufficiency reduces rat plasma leptin concentrations and alters placental leptin transporters: ameliorated with enhanced milk intake and nutrition.

scientific article published on 29 March 2017

Uteroplacental insufficiency temporally exacerbates salt-induced hypertension associated with a reduced natriuretic response in male rat offspring

scientific article published on 25 April 2018

Uteroplacental restriction in the rat impairs fetal growth in association with alterations in placental growth factors including PTHrP.

scientific article published on 20 January 2005

Vascular effects of PTHrP (1–34) and PTH (1–34) in the human fetal-placental circulation

article

Why do membranes rupture at term? Evidence of increased cellular apoptosis in the supracervical fetal membranes.

scientific article published on May 2007

List of works by Mary E Wlodek

Adolescence and the next generation

Adrenal, metabolic and cardio-renal dysfunction develops after pregnancy in rats born small or stressed by physiological measurements during pregnancy.

Angiotensin receptor blockade in juvenile male rat offspring: Implications for long-term cardio-renal health

Bladder contractions and micturition in fetal sheep: their relation to behavioral states

Brain allopregnanolone in the fetal and postnatal rat in response to uteroplacental insufficiency.

Calcium supplementation does not rescue the programmed adult bone deficits associated with perinatal growth restriction.

Cardio-renal and metabolic adaptations during pregnancy in female rats born small: implications for maternal health and second generation fetal growth

Cardiovascular and renal disease in the adolescent guinea pig after chronic placental insufficiency.

Cross-fostering and improved lactation ameliorates deficits in endocrine pancreatic morphology in growth-restricted adult male rat offspring.

DNA Methyltransferase 1 Controls Nephron Progenitor Cell Renewal and Differentiation

Decreased expression of the rat myometrial relaxin receptor (RXFP1) in late pregnancy is partially mediated by the presence of the conceptus

Decreased urine production in the near-term fetal lamb after maternal ethanol infusion

Delayed myelination and neurodevelopment in male seizure-prone versus seizure-resistant rats.

Developmental programming of bone deficits in growth-restricted offspring

Developmental programming: variations in early growth and adult disease

Differences in white matter structure between seizure prone (FAST) and seizure resistant (SLOW) rat strains

Does perinatal omega-3 polyunsaturated fatty acid deficiency increase appetite signaling?

Effect of high oxygen on placental function in short-term explant cultures

Effect of nuclear factor-kappa B inhibitors and peroxisome proliferator-activated receptor-gamma ligands on PTHrP release from human fetal membranes.

Effect of pregnancy for females born small on later life metabolic disease risk

Effects of inhibition of prostaglandin synthesis on flow and composition of fetal urine, lung liquid, and swallowed fluid in sheep

Effects of prolonged hypoxemia on fetal renal function and amniotic fluid volume in sheep

Effects of prostaglandin E2 on renal function and lung liquid dynamics in foetal sheep

Effects of uteroplacental insufficiency and reducing litter size on maternal mammary function and postnatal offspring growth.

Effects of uteroplacental restriction on the relaxin-family receptors, Lgr7 and Lgr8, in the uterus of late pregnant rats

Embryo transfer cannot delineate between the maternal pregnancy environment and germ line effects in the transgenerational transmission of disease in rats

Endocrine responses of fetal sheep to prolonged hypoxemia with and without acidemia: relation to urine production

Endurance training in early life results in long-term programming of heart mass in rats

Evaluation of right heart function in a rat model using modified echocardiographic views

Exercise as an intervention to improve metabolic outcomes after intrauterine growth restriction

Exercise early in life in rats born small does not normalize reductions in skeletal muscle PGC-1α in adulthood

Exercise initiated during pregnancy in rats born growth restricted alters placental mTOR and nutrient transporter expression

Experimental and Human Evidence for Lipocalin-2 (Neutrophil Gelatinase-Associated Lipocalin [NGAL]) in the Development of Cardiac Hypertrophy and heart failure

Expression and localisation of GLUT1 and GLUT12 glucose transporters in the pregnant and lactating rat mammary gland.

Fathers that are born small program alterations in the next-generation preimplantation rat embryos.

Fetal growth restriction shortens cardiac telomere length, but this is attenuated by exercise in early life

Fetal versus maternal determinants of the reduced fetal and placental growth in spontaneously hypertensive rats

Fetal-maternal fluid and electrolyte relations during chronic fetal urine loss in sheep

First Report Of Active Renin In Rat Amniotic Fluid

Growth restriction alters adult spatial memory and sensorimotor gating in a sex-specific manner.

Growth restriction before and after birth increases kinase signaling pathways in the adult rat heart

Growth restriction before or after birth reduces nephron number and increases blood pressure in male rats

Growth restriction in the rat alters expression of cardiac JAK/STAT genes in a sex-specific manner.

Identification of the Alzheimer's disease amyloid precursor protein (APP) and its homologue APLP2 as essential modulators of glucose and insulin homeostasis and growth

Impact of Intrauterine Growth Restriction on the Capillarization of the Early Postnatal Rat Heart

Impact of low dose prenatal ethanol exposure on glucose homeostasis in Sprague-Dawley rats aged up to eight months

Improved lactational nutrition and postnatal growth ameliorates impairment of glucose tolerance by uteroplacental insufficiency in male rat offspring.

Insulin-like Growth Factors and Foetal Programming—A Workshop Report

Intrauterine Growth Restriction Alters the Postnatal Development of the Rat Cerebellum

Intrauterine expression of parathyroid hormone-related protein in normal and pre-eclamptic pregnancies

Lack of evidence for a role for either the in utero or suckling periods in the exaggerated salt preference of the spontaneously hypertensive rat

Leptin in pregnancy and development: a contributor to adulthood disease?

Localization of relaxin receptors in arteries and veins, and region-specific increases in compliance and bradykinin-mediated relaxation after in vivo serelaxin treatment

Locations and molecular forms of gastrin-releasing peptide-like immunoreactive entities in ovine pregnancy

Long-term alteration in maternal blood pressure and renal function after pregnancy in normal and growth-restricted rats

Low female birth weight and advanced maternal age programme alterations in next-generation blastocyst development

Maternal adaptations and inheritance in the transgenerational programming of adult disease

Maternal alcohol intake around the time of conception causes glucose intolerance and insulin insensitivity in rat offspring, which is exacerbated by a postnatal high-fat diet

Maternal exercise and growth restriction in rats alters placental angiogenic factors and blood space area in a sex-specific manner

Maternal exercise in rats upregulates the placental insulin-like growth factor system with diet- and sex-specific responses: minimal effects in mothers born growth restricted

Maternal growth restriction and stress exposure in rats differentially alters expression of components of the placental glucocorticoid barrier and nutrient transporters.

Maternal obesity in females born small: Pregnancy complications and offspring disease risk

Maternal stress does not exacerbate long-term bone deficits in female rats born growth restricted, with differential effects on offspring bone health

Moderate prenatal ethanol exposure in the rat promotes kidney cell apoptosis, nephron deficits, and sex-specific kidney dysfunction in adult offspring

Normal Lactational Environment Restores Nephron Endowment and Prevents Hypertension after Placental Restriction in the Rat

Normal lactational environment restores cardiomyocyte number after uteroplacental insufficiency: implications for the preterm neonate

Normal mammary gland growth and lactation capacity in pregnant relaxin-deficient mice

Parathyroid hormone(1-34) and parathyroid hormone-related protein(1-34) stimulate calcium release from human syncytiotrophoblast basal membranes via a common receptor

Parathyroid hormone-related protein (PTHrP) concentrations in human amniotic fluid during gestation and at the time of labour

Parathyroid hormone-related protein (PTHrP) mRNA splicing and parathyroid hormone/PTHrP receptor mRNA expression in human placenta and fetal membranes

Parathyroid hormone-related protein(1-34) in gestational fluids and release from human gestational tissues

Periconceptional alcohol consumption causes fetal growth restriction and increases glycogen accumulation in the late gestation rat placenta.

Periconceptional alcohol exposure causes female-specific perturbations to trophoblast differentiation and placental formation in the rat

Periconceptional ethanol exposure induces a sex specific diuresis and increase in AQP2 and AVPR2 in the kidneys of aged rat offspring

Physiological skeletal gains and losses in rat mothers during pregnancy and lactation are not observed following uteroplacental insufficiency

Plasma adrenocorticotropic hormone and cortisol and adrenal blood flow during sustained hypoxemia in fetal sheep

Possible role of uterine contractions in the short-term fluctuations of plasma ACTH concentration in fetal sheep

Pregnancy in aged rats that were born small: cardiorenal and metabolic adaptations and second-generation fetal growth

Pregnant growth restricted female rats have bone gains during late gestation which contributes to second generation adolescent and adult offspring having normal bone health.