List of works - Barbara Laughton

African Multi-Site 2-Year Neuropsychological Study of School-Age Children Perinatally Infected, Exposed, and Unexposed to Human Immunodeficiency Virus

scientific article published on 18 December 2019

Altered brain morphometry in 7-year old HIV-infected children on early ART.

scientific article published on 5 December 2017

Assessing the performance of different DTI motion correction strategies in the presence of EPI distortion correction.

scientific article published on 20 July 2016

Association between caregiver depression symptoms and child executive functioning. Results from an observational study carried out in four sub-Saharan countries

scientific article published on 28 August 2019

Building capacity in neurodevelopment assessment of children in sub-Saharan Africa: A quality assurance model to implement standardized neurodevelopment testing

scientific article published on 14 August 2018

Corpus callosum thickness on mid-sagittal MRI as a marker of brain volume: a pilot study in children with HIV-related brain disease and controls.

scientific article published on 27 January 2015

Correlating brain volume and callosal thickness with clinical and laboratory indicators of disease severity in children with HIV-related brain disease.

scientific article published on 23 May 2014

Cortical structural changes related to early antiretroviral therapy (ART) interruption in perinatally HIV-infected children at 5 years of age

scientific article published on 10 February 2021

Diagnostic accuracy of the Molteno Adapted Scale for developmental delay in South African toddlers

article

Diffusion tensor imaging point to ongoing functional impairment in HIV-infected children at age 5, undetectable using standard neurodevelopmental assessments

scientific article published on 19 May 2020

Early Antiretroviral Therapy in HIV-Infected Children Is Associated with Diffuse White Matter Structural Abnormality and Corpus Callosum Sparing

scientific article published on 18 August 2016

Early Antiretroviral Therapy in South African Children Reduces HIV-1-Infected Cells and Cell-Associated HIV-1 RNA in Blood Mononuclear Cells.

scientific article

Early antiretroviral therapy improves neurodevelopmental outcomes in infants

scientific article

Favourable outcome in a child with symptomatic diagnosis of Glutaric aciduria type 1 despite vertical HIV infection and minor head trauma.

scientific article published on 9 February 2018

Five year neurodevelopment outcomes of perinatally HIV-infected children on early limited or deferred continuous antiretroviral therapy. ⬇️

scientific article published in May 2018

Functional Connectivity Alterations between Networks and Associations with Infant Immune Health within Networks in HIV Infected Children on Early Treatment: A Study at 7 Years

scientific article published in January 2017

HIV encephalopathy with bilateral lower limb spasticity: gross motor function and antiretroviral therapy.

scientific article published on 23 January 2017

HIV encephalopathy with bilateral lower limb spasticity: upper limb motor function and level of activity and participation

scientific article published on 30 August 2016

HIV-1 DNA decay is faster in children who initiate ART shortly after birth than later

scientific article published on 01 August 2019

HIV-associated CD4+/CD8+ depletion in infancy is associated with neurometabolic reductions in the basal ganglia at age 5 years despite early antiretroviral therapy

scientific article published on 8 March 2016

Hearing assessment data in HIV-infected and uninfected children of Cape Town, South Africa

scientific article

Hearing sensitivity in perinatally HIV-infected children.

scientific article published on 23 May 2014

Larger Subcortical Gray Matter Structures and Smaller Corpora Callosa at Age 5 Years in HIV Infected Children on Early ART.

scientific article published on 2 November 2017

Late Onset HIV Encephalopathy in Children with Long-Standing Virologic Suppression Followed by Slow Spontaneous Recovery despite No Change in Antiretroviral Therapy -Four Case Reports

scientific article

Longitudinal increases of brain metabolite levels in 5-10 year old children.

scientific article

MRS suggests multi-regional inflammation and white matter axonal damage at 11 years following perinatal HIV infection

scientific article published on 19 November 2020

Maternal post-traumatic stress disorder, depression and alcohol dependence and child behaviour outcomes in mother-child dyads infected with HIV: a longitudinal study

scientific article published on 10 December 2013

Motion artifact reduction in pediatric diffusion tensor imaging using fast prospective correction

scientific article published on 17 June 2014

Neurodevelopment at 11 months after starting antiretroviral therapy within 3 weeks of life

scientific article published on 30 October 2019

Neurodevelopment in perinatally HIV-infected children: a concern for adolescence

scientific article published on 18 June 2013

Neurodevelopmental outcome of HIV-exposed but uninfected infants in the Mother and Infants Health Study, Cape Town, South Africa

scientific article published on 13 November 2017

Neuropsychological performance in African children with HIV enrolled in a multisite antiretroviral clinical trial.

scientific article published on 2 November 2017

No evidence of HIV replication in children on antiretroviral therapy.

scientific article published on 11 September 2017

Perinatal HIV Infection or Exposure Is Associated With Low N-Acetylaspartate and Glutamate in Basal Ganglia at Age 9 but Not 7 Years.

scientific article

Quality of 186 child brain spectra using motion and B0 shim navigated single voxel spectroscopy.

scientific article

Rapid decline of HIV-1 DNA and RNA in infants starting very early ART may pose a diagnostic challenge

scientific article published on 13 January 2018

Recovery of HIV encephalopathy in perinatally infected children on antiretroviral therapy

scientific article published on 10 August 2020

Should efavirenz be used in children and, if so, how?

scientific article published on 12 February 2019

Spastic diplegia in children with HIV encephalopathy: first description of gait and physical status

scientific article published on 3 November 2013

Validity of Neuropsychological Testing in Young African Children Affected by HIV

article

White Matter Abnormalities in Children with HIV Infection and Exposure

scientific article published on 29 September 2017

White matter signal abnormalities in children with suspected HIV-related neurologic disease on early combination antiretroviral therapy

scientific article

List of works by Barbara Laughton

African Multi-Site 2-Year Neuropsychological Study of School-Age Children Perinatally Infected, Exposed, and Unexposed to Human Immunodeficiency Virus

Altered brain morphometry in 7-year old HIV-infected children on early ART.

Assessing the performance of different DTI motion correction strategies in the presence of EPI distortion correction.

Association between caregiver depression symptoms and child executive functioning. Results from an observational study carried out in four sub-Saharan countries

Building capacity in neurodevelopment assessment of children in sub-Saharan Africa: A quality assurance model to implement standardized neurodevelopment testing

Corpus callosum thickness on mid-sagittal MRI as a marker of brain volume: a pilot study in children with HIV-related brain disease and controls.

Correlating brain volume and callosal thickness with clinical and laboratory indicators of disease severity in children with HIV-related brain disease.

Cortical structural changes related to early antiretroviral therapy (ART) interruption in perinatally HIV-infected children at 5 years of age

Diagnostic accuracy of the Molteno Adapted Scale for developmental delay in South African toddlers

Diffusion tensor imaging point to ongoing functional impairment in HIV-infected children at age 5, undetectable using standard neurodevelopmental assessments

Early Antiretroviral Therapy in HIV-Infected Children Is Associated with Diffuse White Matter Structural Abnormality and Corpus Callosum Sparing

Early Antiretroviral Therapy in South African Children Reduces HIV-1-Infected Cells and Cell-Associated HIV-1 RNA in Blood Mononuclear Cells.

Early antiretroviral therapy improves neurodevelopmental outcomes in infants

Favourable outcome in a child with symptomatic diagnosis of Glutaric aciduria type 1 despite vertical HIV infection and minor head trauma.

Five year neurodevelopment outcomes of perinatally HIV-infected children on early limited or deferred continuous antiretroviral therapy. ⬇️

Functional Connectivity Alterations between Networks and Associations with Infant Immune Health within Networks in HIV Infected Children on Early Treatment: A Study at 7 Years

HIV encephalopathy with bilateral lower limb spasticity: gross motor function and antiretroviral therapy.

HIV encephalopathy with bilateral lower limb spasticity: upper limb motor function and level of activity and participation

HIV-1 DNA decay is faster in children who initiate ART shortly after birth than later

HIV-associated CD4+/CD8+ depletion in infancy is associated with neurometabolic reductions in the basal ganglia at age 5 years despite early antiretroviral therapy

Hearing assessment data in HIV-infected and uninfected children of Cape Town, South Africa

Hearing sensitivity in perinatally HIV-infected children.

Larger Subcortical Gray Matter Structures and Smaller Corpora Callosa at Age 5 Years in HIV Infected Children on Early ART.

Late Onset HIV Encephalopathy in Children with Long-Standing Virologic Suppression Followed by Slow Spontaneous Recovery despite No Change in Antiretroviral Therapy -Four Case Reports

Longitudinal increases of brain metabolite levels in 5-10 year old children.

MRS suggests multi-regional inflammation and white matter axonal damage at 11 years following perinatal HIV infection

Maternal post-traumatic stress disorder, depression and alcohol dependence and child behaviour outcomes in mother-child dyads infected with HIV: a longitudinal study

Motion artifact reduction in pediatric diffusion tensor imaging using fast prospective correction

Neurodevelopment at 11 months after starting antiretroviral therapy within 3 weeks of life

Neurodevelopment in perinatally HIV-infected children: a concern for adolescence

Neurodevelopmental outcome of HIV-exposed but uninfected infants in the Mother and Infants Health Study, Cape Town, South Africa

Neuropsychological performance in African children with HIV enrolled in a multisite antiretroviral clinical trial.

No evidence of HIV replication in children on antiretroviral therapy.

Perinatal HIV Infection or Exposure Is Associated With Low N-Acetylaspartate and Glutamate in Basal Ganglia at Age 9 but Not 7 Years.

Quality of 186 child brain spectra using motion and B0 shim navigated single voxel spectroscopy.

Rapid decline of HIV-1 DNA and RNA in infants starting very early ART may pose a diagnostic challenge

Recovery of HIV encephalopathy in perinatally infected children on antiretroviral therapy

Should efavirenz be used in children and, if so, how?

Spastic diplegia in children with HIV encephalopathy: first description of gait and physical status

Validity of Neuropsychological Testing in Young African Children Affected by HIV

White Matter Abnormalities in Children with HIV Infection and Exposure

White matter signal abnormalities in children with suspected HIV-related neurologic disease on early combination antiretroviral therapy