List of works - Youyong Yuan

A FRET probe with AIEgen as the energy quencher: dual signal turn-on for self-validated caspase detection.

scientific article published on 16 March 2016

A General Strategy for Macrotheranostic Prodrug Activation: Synergy between the Acidic Tumor Microenvironment and Bioorthogonal Chemistry

scientific article published on 30 January 2020

A General Strategy for Macrotheranostic Prodrug Activation: Synergy between the Acidic Tumor Microenvironment and Bioorthogonal Chemistry

scientific article published in 2020

A Highly Efficient and Photostable Photosensitizer with Near-Infrared Aggregation-Induced Emission for Image-Guided Photodynamic Anticancer Therapy.

scientific article published on 3 July 2017

A Photoactivatable AIE Polymer for Light-Controlled Gene Delivery: Concurrent Endo/Lysosomal Escape and DNA Unpacking.

scientific article published on 19 June 2015

A biosensor based on self-clickable AIEgen: a signal amplification strategy for ultrasensitive immunoassays.

scientific article published on 26 April 2017

A light-up probe with aggregation-induced emission characteristics (AIE) for selective imaging, naked-eye detection and photodynamic killing of Gram-positive bacteria.

scientific article published in July 2015

A platinum prodrug conjugated with a photosensitizer with aggregation-induced emission (AIE) characteristics for drug activation monitoring and combinatorial photodynamic-chemotherapy against cisplatin resistant cancer cells.

scientific article

A self-reporting AIE probe with a built-in singlet oxygen sensor for targeted photodynamic ablation of cancer cells.

scientific article

AIEgen based drug delivery systems for cancer therapy

article

Biocompatible conjugated polymer nanoparticles for efficient photothermal tumor therapy

scientific article

Bioorthogonal Equipping CAR-T Cells with Hyaluronidase and Checkpoint Blocking Antibody for Enhanced Solid Tumor Immunotherapy

scientific article published in 2022

Bioorthogonal Pretargeting Strategy for Anchoring Activatable Photosensitizers on Plasma Membranes for Effective Photodynamic Therapy

scientific article published in 2021

Bioorthogonal Turn-On Probe Based on Aggregation-Induced Emission Characteristics for Cancer Cell Imaging and Ablation

scientific article published on 15 April 2016

Bioorthogonal chemistry and illumination controlled programmed size-changeable nanomedicine for synergistic photodynamic and hypoxia-activated therapy

scientific article published in 2022

Conjugated polymer and drug co-encapsulated nanoparticles for chemo- and photo-thermal combination therapy with two-photon regulated fast drug release.

scientific article published on February 2015

Conjugated-polyelectrolyte-based polyprodrug: targeted and image-guided photodynamic and chemotherapy with on-demand drug release upon irradiation with a single light source.

scientific article

Delivery of tacrolimus with cationic lipid-assisted nanoparticles for ulcerative colitis therapy

scientific article published on 01 June 2018

Highly efficient photosensitizers with aggregation-induced emission characteristics obtained through precise molecular design.

scientific article published on 20 July 2017

Image-guided combination chemotherapy and photodynamic therapy using a mitochondria-targeted molecular probe with aggregation-induced emission characteristics

scientific article

Light-up probe based on AIEgens: dual signal turn-on for caspase cascade activation monitoring

scientific article

Micelle-to-vesicle morphological transition via light-induced rapid hydrophilic arm detachment from a star polymer

scientific article published on 16 December 2011

NIR photoregulated chemo- and photodynamic cancer therapy based on conjugated polyelectrolyte-drug conjugate encapsulated upconversion nanoparticles.

scientific article

One-Step Formulation of Targeted Aggregation-Induced Emission Dots for Image-Guided Photodynamic Therapy of Cholangiocarcinoma

scientific article published on 06 April 2017

Rational design of fluorescent light-up probes based on an AIE luminogen for targeted intracellular thiol imaging.

scientific article published on 15 November 2013

Recent progress in polyphosphoesters: from controlled synthesis to biomedical applications.

scientific article published on December 2009

Self-assembled nanoparticles based on PEGylated conjugated polyelectrolyte and drug molecules for image-guided drug delivery and photodynamic therapy.

scientific article

Size-Switchable Nanoparticles with Self-Destructive and Tumor Penetration Characteristics for Site-Specific Phototherapy of Cancer

scientific article published on 03 February 2020

Smart activatable and traceable dual-prodrug for image-guided combination photodynamic and chemo-therapy.

scientific article published on 14 August 2017

Specific light-up bioprobe with aggregation-induced emission and activatable photoactivity for the targeted and image-guided photodynamic ablation of cancer cells.

scientific article published on 11 December 2014

Surface charge switchable nanoparticles based on zwitterionic polymer for enhanced drug delivery to tumor.

scientific article

Temperature-induced morphological change of ABC 3-miktoarm star terpolymer assemblies in aqueous solution

scientific article published on 02 November 2010

Tumor extracellular acidity-activated nanoparticles as drug delivery systems for enhanced cancer therapy.

scientific article published on 07 August 2013

Tumor-Acidity and Bioorthogonal Chemistry-Mediated On-Site Size Transformation Clustered Nanosystem to Overcome Hypoxic Resistance and Enhance Chemoimmunotherapy

scientific article published in 2022

Tumor-acidity and bioorthogonal chemistry-mediated construction and deconstruction of drug depots for ferroptosis under normoxia and hypoxia

scientific article published in 2022

Tumor-responsive fluorescent light-up probe based on a gold nanoparticle/conjugated polyelectrolyte hybrid.

scientific article published on 10 March 2014

Tuning the singlet-triplet energy gap: a unique approach to efficient photosensitizers with aggregation-induced emission (AIE) characteristics

scientific article published on 17 July 2015

Two consecutive click reactions as a general route to functional cyclic polyesters

scientific article published on 07 November 2011

Visualization of drug delivery processes using AIEgens

scientific article

List of works by Youyong Yuan

A FRET probe with AIEgen as the energy quencher: dual signal turn-on for self-validated caspase detection.

A General Strategy for Macrotheranostic Prodrug Activation: Synergy between the Acidic Tumor Microenvironment and Bioorthogonal Chemistry

A General Strategy for Macrotheranostic Prodrug Activation: Synergy between the Acidic Tumor Microenvironment and Bioorthogonal Chemistry

A Highly Efficient and Photostable Photosensitizer with Near-Infrared Aggregation-Induced Emission for Image-Guided Photodynamic Anticancer Therapy.

A Photoactivatable AIE Polymer for Light-Controlled Gene Delivery: Concurrent Endo/Lysosomal Escape and DNA Unpacking.

A biosensor based on self-clickable AIEgen: a signal amplification strategy for ultrasensitive immunoassays.

A light-up probe with aggregation-induced emission characteristics (AIE) for selective imaging, naked-eye detection and photodynamic killing of Gram-positive bacteria.

A platinum prodrug conjugated with a photosensitizer with aggregation-induced emission (AIE) characteristics for drug activation monitoring and combinatorial photodynamic-chemotherapy against cisplatin resistant cancer cells.

A self-reporting AIE probe with a built-in singlet oxygen sensor for targeted photodynamic ablation of cancer cells.

AIEgen based drug delivery systems for cancer therapy

Biocompatible conjugated polymer nanoparticles for efficient photothermal tumor therapy

Bioorthogonal Equipping CAR-T Cells with Hyaluronidase and Checkpoint Blocking Antibody for Enhanced Solid Tumor Immunotherapy

Bioorthogonal Pretargeting Strategy for Anchoring Activatable Photosensitizers on Plasma Membranes for Effective Photodynamic Therapy

Bioorthogonal Turn-On Probe Based on Aggregation-Induced Emission Characteristics for Cancer Cell Imaging and Ablation

Bioorthogonal chemistry and illumination controlled programmed size-changeable nanomedicine for synergistic photodynamic and hypoxia-activated therapy

Conjugated polymer and drug co-encapsulated nanoparticles for chemo- and photo-thermal combination therapy with two-photon regulated fast drug release.

Conjugated-polyelectrolyte-based polyprodrug: targeted and image-guided photodynamic and chemotherapy with on-demand drug release upon irradiation with a single light source.

Delivery of tacrolimus with cationic lipid-assisted nanoparticles for ulcerative colitis therapy

Highly efficient photosensitizers with aggregation-induced emission characteristics obtained through precise molecular design.

Image-guided combination chemotherapy and photodynamic therapy using a mitochondria-targeted molecular probe with aggregation-induced emission characteristics

Light-up probe based on AIEgens: dual signal turn-on for caspase cascade activation monitoring

Micelle-to-vesicle morphological transition via light-induced rapid hydrophilic arm detachment from a star polymer

NIR photoregulated chemo- and photodynamic cancer therapy based on conjugated polyelectrolyte-drug conjugate encapsulated upconversion nanoparticles.

One-Step Formulation of Targeted Aggregation-Induced Emission Dots for Image-Guided Photodynamic Therapy of Cholangiocarcinoma

Rational design of fluorescent light-up probes based on an AIE luminogen for targeted intracellular thiol imaging.

Recent progress in polyphosphoesters: from controlled synthesis to biomedical applications.

Self-assembled nanoparticles based on PEGylated conjugated polyelectrolyte and drug molecules for image-guided drug delivery and photodynamic therapy.

Size-Switchable Nanoparticles with Self-Destructive and Tumor Penetration Characteristics for Site-Specific Phototherapy of Cancer

Smart activatable and traceable dual-prodrug for image-guided combination photodynamic and chemo-therapy.

Specific light-up bioprobe with aggregation-induced emission and activatable photoactivity for the targeted and image-guided photodynamic ablation of cancer cells.

Surface charge switchable nanoparticles based on zwitterionic polymer for enhanced drug delivery to tumor.

Temperature-induced morphological change of ABC 3-miktoarm star terpolymer assemblies in aqueous solution

Tumor extracellular acidity-activated nanoparticles as drug delivery systems for enhanced cancer therapy.

Tumor-Acidity and Bioorthogonal Chemistry-Mediated On-Site Size Transformation Clustered Nanosystem to Overcome Hypoxic Resistance and Enhance Chemoimmunotherapy

Tumor-acidity and bioorthogonal chemistry-mediated construction and deconstruction of drug depots for ferroptosis under normoxia and hypoxia

Tumor-responsive fluorescent light-up probe based on a gold nanoparticle/conjugated polyelectrolyte hybrid.

Tuning the singlet-triplet energy gap: a unique approach to efficient photosensitizers with aggregation-induced emission (AIE) characteristics

Two consecutive click reactions as a general route to functional cyclic polyesters

Visualization of drug delivery processes using AIEgens