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List of works by David Lydall

A Critical Role for Dna2 at Unwound Telomeres

scientific article published on 20 March 2018

A Functional Link Between Bir1 and the Saccharomyces cerevisiae Ctf19 Kinetochore Complex Revealed Through Quantitative Fitness Analysis.

scientific article

A domain of Rad9 specifically required for activation of Chk1 in budding yeast

scientific article

A genome wide analysis of the response to uncapped telomeres in budding yeast reveals a novel role for the NAD+ biosynthetic gene BNA2 in chromosome end protection ⬇️

scientific article published on October 2008

A genome-wide screen identifies the evolutionarily conserved KEOPS complex as a telomere regulator

scientific article

Bayesian hierarchical modelling for inferring genetic interactions in yeast. ⬇️

scientific article

Checkpoint-dependent phosphorylation of Exo1 modulates the DNA damage response

scientific article

Chromatin and the DNA damage response

scientific article

Cis and trans interactions between genes encoding PAF1 complex and ESCRT machinery components in yeast.

scientific article published on 22 March 2018

Colonyzer: automated quantification of micro-organism growth characteristics on solid agar

scientific article

Costs, benefits and redundant mechanisms of adaption to chronic low-dose stress in yeast

scientific article

Customizable views on semantically integrated networks for systems biology.

scientific article published on 16 March 2011

EXO1 plays a role in generating type I and type II survivors in budding yeast

scientific article published on April 2004

EXO1-dependent single-stranded DNA at telomeres activates subsets of DNA damage and spindle checkpoint pathways in budding yeast yku70Delta mutants

scientific article published on August 2002

Exo1 and Rad24 differentially regulate generation of ssDNA at telomeres of Saccharomyces cerevisiae cdc13-1 mutants

scientific article

Fast Bayesian parameter estimation for stochastic logistic growth models

scientific article published on 4 June 2014

Genetic Networks Required to Coordinate Chromosome Replication by DNA Polymerases α, δ, and ε in Saccharomyces cerevisiae.

scientific article published on 21 August 2015

Genome-Wide Quantitative Fitness Analysis (QFA) of Yeast Cultures

scientific article published in January 2018

Genome-wide analysis to identify pathways affecting telomere-initiated senescence in budding yeast.

scientific article published on August 2011

Hiding at the ends of yeast chromosomes: telomeres, nucleases and checkpoint pathways

scientific article

Histone methyltransferase Dot1 and Rad9 inhibit single-stranded DNA accumulation at DSBs and uncapped telomeres

scientific article published on 17 April 2008

Interplay between nonsense-mediated mRNA decay and DNA damage response pathways reveals that Stn1 and Ten1 are the key CST telomere-cap components

scientific article published on 15 May 2014

Linear chromosome maintenance in the absence of essential telomere-capping proteins

scientific article

MRX protects telomeric DNA at uncapped telomeres of budding yeast cdc13-1 mutants.

scientific article published on 12 June 2006

Mec1 and Rad53 inhibit formation of single-stranded DNA at telomeres of Saccharomyces cerevisiae cdc13-1 mutants

scientific article published on February 2004

Mrc1 protects uncapped budding yeast telomeres from exonuclease EXO1.

scientific article

Overlapping open reading frames strongly reduce human and yeast STN1 gene expression and affect telomere function

article

Paf1 and Ctr9, core components of the PAF1 complex, maintain low levels of telomeric repeat containing RNA.

scientific article published on 14 November 2017

Pentose phosphate pathway function affects tolerance to the G-quadruplex binder TMPyP4

scientific article

Pho4 mediates phosphate acquisition in Candida albicans and is vital for stress resistance and metal homeostasis

scientific article

Pif1- and Exo1-dependent nucleases coordinate checkpoint activation following telomere uncapping.

scientific article

Quantitative Amplification of Single-Stranded DNA ⬇️

scientific article published on January 1, 2012

Quantitative Fitness Analysis Identifies exo1∆ and Other Suppressors or Enhancers of Telomere Defects in Schizosaccharomyces pombe.

scientific article published on 13 July 2015

Quantitative fitness analysis shows that NMD proteins and many other protein complexes suppress or enhance distinct telomere cap defects.

scientific article

Rif1 and Exo1 regulate the genomic instability following telomere losses

scientific article published on 22 March 2016

Similarities and differences between "uncapped" telomeres and DNA double-strand breaks.

scientific article published on 28 December 2011

Simple, Non-radioactive Measurement of Single-Stranded DNA at Telomeric, Sub-telomeric, and Genomic Loci in Budding Yeast ⬇️

scientific article published on January 1, 2012

Survival and growth of yeast without telomere capping by Cdc13 in the absence of Sgs1, Exo1, and Rad9.

scientific article

Systematic Analysis of the DNA Damage Response Network in Telomere Defective Budding Yeast

scientific article

Taming the tiger by the tail: modulation of DNA damage responses by telomeres

scientific article published on 23 July 2009

Telomerase- and recombination-independent immortalization of budding yeast

scientific article published on 15 October 2004

Telomere maintenance and survival in saccharomyces cerevisiae in the absence of telomerase and RAD52.

scientific article published on 20 April 2009

The 9-1-1 checkpoint clamp coordinates resection at DNA double strand breaks

scientific article published on 29 April 2015

The 9-1-1 checkpoint clamp stimulates DNA resection by Dna2-Sgs1 and Exo1.

scientific article

The PAL-mechanism of chromosome maintenance: causes and consequences.

scientific article

The Telomere Binding Protein Cdc13 and the Single-Stranded DNA Binding Protein RPA Protect Telomeric DNA from Resection by Exonucleases

scientific article published on 8 August 2015

The contribution of non-essential Schizosaccharomyces pombe genes to fitness in response to altered nutrient supply and target of rapamycin activity.

scientific article

The yeast copper response is regulated by DNA damage

scientific article published on 19 August 2013

Vps74 Connects the Golgi Apparatus and Telomeres in Saccharomyces cerevisiae.

scientific article published on 28 March 2018

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