List of works - Lea-Ann Kirkham

A PCR-high-resolution melt assay for rapid differentiation of nontypeable Haemophilus influenzae and Haemophilus haemolyticus

scientific article published on 4 December 2013

A practical method for preparation of pneumococcal and nontypeable Haemophilus influenzae inocula that preserves viability and immunostimulatory activity

scientific article

Australian Aboriginal Children with Otitis Media Have Reduced Antibody Titers to Specific Nontypeable Haemophilus influenzae Vaccine Antigens

scientific article

Bacillus licheniformis in geogenic dust induces inflammation in respiratory epithelium.

scientific article

Children with otitis media mount a pneumococcal serotype specific serum IgG and IgA response comparable to healthy controls after pneumococcal conjugate vaccination

scientific article published on 08 February 2012

Chronic HIV-1 Infection Induces B-Cell Dysfunction That Is Incompletely Resolved by Long-Term Antiretroviral Therapy.

scientific article

Complete Deletion of the Fucose Operon in Haemophilus influenzae Is Associated with a Cluster in Multilocus Sequence Analysis-Based Phylogenetic Group II Related to Haemophilus haemolyticus: Implications for Identification and Typing

scientific article

Diversity of nontypeable Haemophilus influenzae strains colonizing Australian Aboriginal and non-Aboriginal children.

scientific article

Duplex Quantitative PCR Assay for Detection of Haemophilus influenzae That Distinguishes Fucose- and Protein D-Negative Strains.

scientific article published on 22 June 2016

Evidence of functional cell-mediated immune responses to nontypeable Haemophilus influenzae in otitis-prone children.

scientific article

Haemophilus haemolyticus Interaction with Host Cells Is Different to Nontypeable Haemophilus influenzae and Prevents NTHi Association with Epithelial Cells

scientific article published on 9 May 2016

Haemophilus influenzae: using comparative genomics to accurately identify a highly recombinogenic human pathogen.

scientific article published on 27 August 2015

High detection rates of nucleic acids of a wide range of respiratory viruses in the nasopharynx and the middle ear of children with a history of recurrent acute otitis media.

scientific article

Identification of a detrimental role for NK cells in pneumococcal pneumonia and sepsis in immunocompromised hosts.

scientific article published on 15 April 2005

Identification of invasive serotype 1 pneumococcal isolates that express nonhemolytic pneumolysin.

scientific article

IgG responses to Pneumococcal and Haemophilus influenzae protein antigens are not impaired in children with a history of recurrent acute otitis media.

scientific article

Increased CTLA-4+ T cells may contribute to impaired T helper type 1 immune responses in patients with chronic obstructive pulmonary disease.

scientific article published on 11 February 2017

Molecular surveillance of true nontypeable Haemophilus influenzae: an evaluation of PCR screening assays.

scientific article

Molecular tools for differentiation of non-typeable Haemophilus influenzae from Haemophilus haemolyticus

scientific article

Moraxella catarrhalis Restriction-Modification Systems are Associated with Phylogenetic Lineage and Disease

scientific article published on 01 November 2018

Nasal Delivery of a Commensal Pasteurellaceae Species Inhibits Nontypeable Haemophilus influenzae Colonization and Delays Onset of Otitis Media in Mice

scientific article published on 23 March 2020

Nasopharyngeal carriage of Haemophilus haemolyticus in otitis-prone and healthy children.

scientific article published on 12 May 2010

Neutrophil extracellular traps and bacterial biofilms in middle ear effusion of children with recurrent acute otitis media--a potential treatment target

scientific article

New findings in the pathogenesis of otitis media

scientific article published on 01 December 2012

No evidence for impaired humoral immunity to pneumococcal proteins in Australian Aboriginal children with otitis media.

scientific article published on 22 November 2016

Otitis-Prone Children Produce Functional Antibodies to Pneumolysin and Pneumococcal Polysaccharides.

scientific article published on 28 December 2016

PCV7- and PCV10-Vaccinated Otitis-Prone Children in New Zealand Have Similar Pneumococcal and Densities in Their Nasopharynx and Middle Ear

article

Predominance of nontypeable Haemophilus influenzae in children with otitis media following introduction of a 3+0 pneumococcal conjugate vaccine schedule.

scientific article

Production of IgG antibodies to pneumococcal polysaccharides is associated with expansion of ICOS+ circulating memory T follicular-helper cells which is impaired by HIV infection

scientific article

Role of viral and bacterial pathogens in causing pneumonia among Western Australian children: a case-control study protocol.

scientific article published on 16 March 2018

The Contribution of Geogenic Particulate Matter to Lung Disease in Indigenous Children

scientific article published on 24 July 2019

Trivalent influenza vaccine and febrile adverse events in Australia, 2010: clinical features and potential mechanisms.

scientific article

Understanding the aetiology and resolution of chronic otitis media from animal and human studies.

scientific article published in November 2017

List of works by Lea-Ann Kirkham

A PCR-high-resolution melt assay for rapid differentiation of nontypeable Haemophilus influenzae and Haemophilus haemolyticus

A practical method for preparation of pneumococcal and nontypeable Haemophilus influenzae inocula that preserves viability and immunostimulatory activity

Australian Aboriginal Children with Otitis Media Have Reduced Antibody Titers to Specific Nontypeable Haemophilus influenzae Vaccine Antigens

Bacillus licheniformis in geogenic dust induces inflammation in respiratory epithelium.

Children with otitis media mount a pneumococcal serotype specific serum IgG and IgA response comparable to healthy controls after pneumococcal conjugate vaccination

Chronic HIV-1 Infection Induces B-Cell Dysfunction That Is Incompletely Resolved by Long-Term Antiretroviral Therapy.

Complete Deletion of the Fucose Operon in Haemophilus influenzae Is Associated with a Cluster in Multilocus Sequence Analysis-Based Phylogenetic Group II Related to Haemophilus haemolyticus: Implications for Identification and Typing

Diversity of nontypeable Haemophilus influenzae strains colonizing Australian Aboriginal and non-Aboriginal children.

Duplex Quantitative PCR Assay for Detection of Haemophilus influenzae That Distinguishes Fucose- and Protein D-Negative Strains.

Evidence of functional cell-mediated immune responses to nontypeable Haemophilus influenzae in otitis-prone children.

Haemophilus haemolyticus Interaction with Host Cells Is Different to Nontypeable Haemophilus influenzae and Prevents NTHi Association with Epithelial Cells

Haemophilus influenzae: using comparative genomics to accurately identify a highly recombinogenic human pathogen.

High detection rates of nucleic acids of a wide range of respiratory viruses in the nasopharynx and the middle ear of children with a history of recurrent acute otitis media.

Identification of a detrimental role for NK cells in pneumococcal pneumonia and sepsis in immunocompromised hosts.

Identification of invasive serotype 1 pneumococcal isolates that express nonhemolytic pneumolysin.

IgG responses to Pneumococcal and Haemophilus influenzae protein antigens are not impaired in children with a history of recurrent acute otitis media.

Increased CTLA-4+ T cells may contribute to impaired T helper type 1 immune responses in patients with chronic obstructive pulmonary disease.

Molecular surveillance of true nontypeable Haemophilus influenzae: an evaluation of PCR screening assays.

Molecular tools for differentiation of non-typeable Haemophilus influenzae from Haemophilus haemolyticus

Moraxella catarrhalis Restriction-Modification Systems are Associated with Phylogenetic Lineage and Disease

Nasal Delivery of a Commensal Pasteurellaceae Species Inhibits Nontypeable Haemophilus influenzae Colonization and Delays Onset of Otitis Media in Mice

Nasopharyngeal carriage of Haemophilus haemolyticus in otitis-prone and healthy children.

Neutrophil extracellular traps and bacterial biofilms in middle ear effusion of children with recurrent acute otitis media--a potential treatment target

New findings in the pathogenesis of otitis media

No evidence for impaired humoral immunity to pneumococcal proteins in Australian Aboriginal children with otitis media.

Otitis-Prone Children Produce Functional Antibodies to Pneumolysin and Pneumococcal Polysaccharides.

PCV7- and PCV10-Vaccinated Otitis-Prone Children in New Zealand Have Similar Pneumococcal and Densities in Their Nasopharynx and Middle Ear

Predominance of nontypeable Haemophilus influenzae in children with otitis media following introduction of a 3+0 pneumococcal conjugate vaccine schedule.

Production of IgG antibodies to pneumococcal polysaccharides is associated with expansion of ICOS+ circulating memory T follicular-helper cells which is impaired by HIV infection

Role of viral and bacterial pathogens in causing pneumonia among Western Australian children: a case-control study protocol.

The Contribution of Geogenic Particulate Matter to Lung Disease in Indigenous Children

Trivalent influenza vaccine and febrile adverse events in Australia, 2010: clinical features and potential mechanisms.

Understanding the aetiology and resolution of chronic otitis media from animal and human studies.