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List of works by William Harnett

A novel therapeutic approach targeting articular inflammation using the filarial nematode-derived phosphorylcholine-containing glycoprotein ES-62.

scientific article

Acanthocheilonema viteae: phosphorylcholine is attached to the major excretory-secretory product via an N-linked glycan

scientific article published on 01 December 1993

Allergy and parasites

scientific article published on 12 February 2013

An oligonucleotide probe specific for Onchocerca volvulus

scientific article

Antigen receptor signaling is subverted by an immunomodulatory product secreted by a filarial nematode

scientific article

Apicomplexan autophagy and modulation of autophagy in parasite-infected host cells

scientific article

Avoiding detection: parasites and the immune system

scientific article published on 01 October 2002

Biosynthetic radiolabelling of excretions-secretions of adult male Onchocerca gibsoni

scientific article published on 01 July 1994

Brugia malayi Antigen (BmA) Inhibits HIV-1 Trans-Infection but Neither BmA nor ES-62 Alter HIV-1 Infectivity of DC Induced CD4+ Th-Cells

scientific article published on 25 January 2016

Characterization of the surface polypeptides of Strongyloides ratti: a comparison of homogonic and heterogonic strains

scientific article published on 01 March 1994

Cloning of a species-specific DNA probe from Onchocerca gibsoni

scientific article

Cloning of specific diagnostic antigens of Onchocerca volvulus

scientific article

DNA-based detection of onchocerca volvulus.

scientific article

Designing anti-inflammatory drugs from parasitic worms: a synthetic small molecule analogue of the Acanthocheilonema viteae product ES-62 prevents development of collagen-induced arthritis.

scientific article

Development of Acanthocheilonema viteae in Meriones shawi: absence of microfilariae and production of active ES-62

scientific article published on 22 October 2020

Does Litomosoides sigmodontis synthesize dimethylethanolamine from choline?

scientific article published on 25 September 2007

ES-62 is unable to modulate Toxoplasma gondii-driven Th1 responses and pathology

article

Evaluation of the potential of excretions-secretions (E-S) of Litomosoides carinii to substitute for human filarial E-S

scientific article published on 01 January 1989

Expression of the filarial nematode phosphorylcholine-containing glycoprotein, ES62, is stage specific.

scientific article published in August 2002

Failure of ES-62 to inhibit T-helper type 1 responses to other filarial nematode antigens.

scientific article published on 27 February 2008

From the worm to the pill, the parasitic worm product ES-62 raises new horizons in the treatment of rheumatoid arthritis.

scientific article published on April 2015

Gene inactivation confirms the identity of enzymes involved in nematode phosphorylcholine-N-glycan synthesis.

scientific article published on 2 September 2007

Immunomodulatory properties of ES-62, a phosphorylcholine-containing glycoprotein secreted by Acanthocheilonema viteae

scientific article

Impact of worms and their products on eosinophils and neutrophils in experimental asthma.

scientific article published on August 2013

Increased exposure of parasite antigens at the surface of adult male Schistosoma mansoni exposed to praziquantel in vitro

scientific article published on 01 October 1986

Investigation of strategies with potential for producing a phosphorylcholine-free version of the filarial nematode immunomodulator, ES-62

scientific article published on 01 September 2006

Modulation of the host immune system by phosphorylcholine-containing glycoproteins secreted by parasitic filarial nematodes

scientific article

Onchocerca antigens in protection, diagnosis and pathology.

scientific article

Onchocerca ochengi acquisition in zebu Gudali cattle exposed to natural transmission: parasite population dynamics and IgG antibody subclass responses to Ov10/Ov11 recombinant antigens.

scientific article published in June 2004

Origin, kinetics of circulation and fate in vivo of the major excretory-secretory product of Acanthocheilonema viteae

scientific article published on 01 October 1989

Parasite excretory-secretory products and their effects on metabolic syndrome

scientific article published on 9 January 2017

Parasite modulation of the immune response

scientific article published on 01 October 2005

Prevention of attachment of phosphorylcholine to a major excretory-secretory product of Acanthocheilonema viteae using tunicamycin

scientific article published on 01 April 1996

Prophylactic and therapeutic treatment with a synthetic analogue of a parasitic worm product prevents experimental arthritis and inhibits IL-1β production via NRF2-mediated counter-regulation of the inflammasome ⬇️

scientific article published on 11 May 2015

Rapid changes in the surface of parasitic nematodes during transition from pre- to post-parasitic forms

scientific article published on 01 July 1993

Schistosoma mansoni: exposure in vitro of adult male surface antigens

scientific article published on 01 April 1986

Secretory products of helminth parasites as immunomodulators.

scientific article

Site-specific glycoproteomic characterization of ES-62: The major secreted product of the parasitic worm Acanthocheilonema viteae

scientific article published on 01 July 2019

Small molecule analogues of the immunomodulatory parasitic helminth product ES-62 have anti-allergy properties

scientific article

Stage-specific and species-specific differences in the production of the mRNA and protein for the filarial nematode secreted product, ES-62.

scientific article published in January 2004

Structural/functional aspects of ES-62--a secreted immunomodulatory phosphorylcholine-containing filarial nematode glycoprotein

scientific article

Structure and synthesis of nematode phosphorylcholine-containing glycoconjugates.

scientific article

Studies on a 14-kilodalton surface protein of Onchocerca microfilariae.

scientific article

Successful vaccination against Onchocerca ochengi infestation in cattle using live Onchocerca volvulus infective larvae.

scientific article published in March 2007

Suppression of inflammatory arthritis by the parasitic worm product ES-62 is associated with epigenetic changes in synovial fibroblasts

scientific article published on 08 November 2021

Surface antigens of male worms and microfilariae of Onchocerca gibsoni

scientific article published on 01 February 1991

The Carbohydrate-linked Phosphorylcholine of the Parasitic Nematode Product ES-62 Modulates Complement Activation.

scientific article published on 4 April 2016

The Interaction of Membrane-active Compounds with the Surfaces of Schistosomula and Adult Schistosoma mansoni.

scientific article published on January 1982

The anthelmintic action of praziquantel

scientific article published on 01 May 1988

The effects of retinol (vitamin A alcohol) and various non-ionic detergents on he surfaces of schistosomula and adult Schistosoma mansoni

scientific article published on 01 March 1982

The helminth product ES-62 protects against septic shock via Toll-like receptor 4–dependent autophagosomal degradation of the adaptor MyD88 ⬇️

scientific article published on February 27, 2011

The immunomodulatory parasitic worm product ES-62 reduces lupus-associated accelerated atherosclerosis in a mouse model

scientific article

The parasitic worm product ES-62 promotes health- and life-span in a high calorie diet-accelerated mouse model of ageing

scientific article published on 12 March 2020

The parasitic worm product ES-62 targets myeloid differentiation factor 88-dependent effector mechanisms to suppress antinuclear antibody production and proteinuria in MRL/lpr mice

scientific article published on April 2015

The parasitic worm-derived immunomodulator, ES-62 and its drug-like small molecule analogues exhibit therapeutic potential in a model of chronic asthma

scientific article

The pathology of Plasmodium chabaudi infection is not ameliorated by the secreted filarial nematode immunomodulatory molecule, ES-62.

scientific article published in May 2007

The use of membrane-active compounds to examine the structure of the surface membrane of Schistosoma mansoni

scientific article published on 01 March 1981

Variation in class-specific humoral immune responses of different mouse strains to microfilariae of Dipetalonema viteae.

scientific article

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