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List of works by James Sacchettini

A Sec14-like phosphatidylinositol transfer protein paralog defines a novel class of heme-binding proteins

scientific article published on 11 August 2020

Anion-π Interactions in Computer-Aided Drug Design: Modeling the Inhibition of Malate Synthase by Phenyl-Diketo Acids

scientific article published on 12 September 2018

Bayesian analysis of gene essentiality based on sequencing of transposon insertion libraries.

scientific article

Bedaquiline reprograms central metabolism to reveal glycolytic vulnerability in Mycobacterium tuberculosis

scientific article published on 30 November 2020

Elesclomol alleviates Menkes pathology and mortality by escorting Cu to cuproenzymes in mice

scientific article published on 01 May 2020

Functional genomics screening utilizing mutant mouse embryonic stem cells identifies novel radiation-response genes

scientific article published on 8 April 2015

High-Throughput Differentiation and Screening of a Library of Mutant Stem Cell Clones Defines New Host-Based Genes Involved in Rabies Virus Infection.

scientific article published on 12 May 2015

Impact of immunopathology on the antituberculous activity of pyrazinamide

scientific article published on 17 July 2018

Improvement of the novel inhibitor for Mycobacterium enoyl-acyl carrier protein reductase (InhA): a structure-activity relationship study of KES4 assisted by in silico structure-based drug screening

scientific article published on 09 March 2020

Minocycline and Silver Dual-Loaded Polyphosphoester-Based Nanoparticles for Treatment of Resistant Pseudomonas aeruginosa

scientific article published on 12 March 2019

Opposing reactions in coenzyme A metabolism sensitize Mycobacterium tuberculosis to enzyme inhibition

scientific article published on 01 February 2019

Structure-Guided Drug Design of 6-Substituted Adenosine Analogues as Potent Inhibitors of Mycobacterium tuberculosis Adenosine Kinase

scientific article published on 19 April 2019

Targeting protein biotinylation enhances tuberculosis chemotherapy.

scientific article

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