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List of works by Alexander J Muller

A Sub-Type of Familial Pancreatic Cancer: Evidence and Implications of Loss of Function Polymorphisms and Indoleamine-2,3-Dioxygenase-2.

scientific article published on 6 February 2018

BCR sequences essential for transformation by the BCR-ABL oncogene bind to the ABL SH2 regulatory domain in a non-phosphotyrosine-dependent manner

scientific article

Beyond immunosuppression: reconsidering indoleamine 2,3-dioxygenase as a pathogenic element of chronic inflammation.

scientific article published on May 2010

Bin1 ablation in mammary gland delays tissue remodeling and drives cancer progression

scientific article published on 01 January 2007

Bin3 deletion causes cataracts and increased susceptibility to lymphoma during aging.

scientific article published in March 2008

Cardiac-specific disruption of Bin1 in mice enables a model of stress- and age-associated dilated cardiomyopathy

scientific article published on 01 November 2015

Chronic inflammation that facilitates tumor progression creates local immune suppression by inducing indoleamine 2,3 dioxygenase.

scholarly article

En bloc substitution of the Src homology region 2 domain activates the transforming potential of the c-Abl protein tyrosine kinase ⬇️

scientific article published on April 15, 1993

Host IDO2 Gene Status Influences Tumor Progression and Radiotherapy Response in KRAS-Driven Sporadic Pancreatic Cancers

scientific article published on 28 September 2018

Indoleamine 2,3-Dioxygenase and Its Therapeutic Inhibition in Cancer

scientific article published on 21 September 2017

Indoleamine 2,3-dioxygenase in T-cell tolerance and tumoral immune escape.

scientific article

Indoleamine 2,3-dioxygenase in cancer: targeting pathological immune tolerance with small-molecule inhibitors.

scientific article

Indoleamine 2,3-dioxygenase in immune suppression and cancer.

scientific article published on February 2007

Indoleamine 2,3-dioxygenase is the anticancer target for a novel series of potent naphthoquinone-based inhibitors.

scientific article

Indoximod: An Immunometabolic Adjuvant That Empowers T Cell Activity in Cancer

article published in 2018

Inhibiting IDO pathways to treat cancer: lessons from the ECHO-301 trial and beyond

scientific article published on 10 September 2018

Inhibition of indoleamine 2,3-dioxygenase, an immunoregulatory target of the cancer suppression gene Bin1, potentiates cancer chemotherapy.

scientific article

Non-hematopoietic expression of IDO is integrally required for inflammatory tumor promotion

scientific article

Oncogenic activation of c-ABL by mutation within its last exon.

scientific article published on August 1993

Peptide vaccination directed against IDO1-expressing immune cells elicits CD8+ and CD4+ T-cell-mediated antitumor immunity and enhanced anti-PD1 responses

scientific article published on 01 July 2020

Structure-activity study of brassinin derivatives as indoleamine 2,3-dioxygenase inhibitors.

scientific article published on January 2006

Targeted disruption of the murine Bin1/Amphiphysin II gene does not disable endocytosis but results in embryonic cardiomyopathy with aberrant myofibril formation.

scientific article

Targeting the mechanisms of tumoral immune tolerance with small-molecule inhibitors.

scientific article

The gas5 gene is disrupted by a frameshift mutation within its longest open reading frame in several inbred mouse strains and maps to murine chromosome 1.

scientific article published in September 1998

The immunoregulatory enzyme IDO paradoxically drives B cell-mediated autoimmunity

scientific article published on June 2009

Tyrosine kinase activity and transformation potency of bcr-abl oncogene products.

scientific article

Zinc protoporphyrin IX stimulates tumor immunity by disrupting the immunosuppressive enzyme indoleamine 2,3-dioxygenase.

scientific article

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