List of works - Juan C. Gómez-Fernández

1,2-Dioleoylglycerol promotes calcium-induced fusion in phospholipid vesicles

scientific article published on October 1, 1992

A comparative study of the activation of protein kinase C alpha by different diacylglycerol isomers.

scientific article

A comparison of the membrane binding properties of C1B domains of PKCgamma, PKCdelta, and PKCepsilon.

scientific article published on May 2009

A kinetic study of the interaction between mitochondrial F1 adenosine triphosphatase and adenylyl imidodiphosphate and guanylyl imidodiphosphate ⬇️

scientific article published on March 15, 1983

A kinetic study of the interaction of vanadate with the Ca2+ + Mg2+-dependent ATPase from sarcoplasmic reticulum ⬇️

scientific article published on July 1, 1984

A new phosphatidylinositol 4,5-bisphosphate-binding site located in the C2 domain of protein kinase Calpha.

scientific article published on 7 November 2002

A study on the interactions of surfactin with phospholipid vesicles

scientific article published on 01 May 1999

A thermodynamic analysis of the interaction between the mitochondrial coupling adenosine triphosphatase and its naturally occurring inhibitor protein ⬇️

scientific article published on December 15, 1978

ATP enhances neuronal differentiation of PC12 cells by activating PKCα interactions with cytoskeletal proteins.

scientific article

Activation of protein kinase C alpha by lipid mixtures containing different proportions of diacylglycerols

scientific article published on 01 December 2001

Alcohol dehydrogenase from the hyperthermophilic archaeon Pyrobaculum aerophilum: stability at high temperature.

scientific article

Anticancer Agent Edelfosine Exhibits a High Affinity for Cholesterol and Disorganizes Liquid-Ordered Membrane Structures

scientific article published on 05 July 2018

Both idebenone and idebenol are localized near the lipid-water interface of the membrane and increase its fluidity

scientific article

C2 domains of protein kinase C isoforms alpha, beta, and gamma: activation parameters and calcium stoichiometries of the membrane-bound state

scientific journal article

Calorimetric Study of the Interaction of the C2 Domains of Classical Protein Kinase C Isoenzymes with Ca2+and Phospholipids†

scientific article published on 01 September 2004

Capsaicin Fluidifies the Membrane and Localizes Itself near the Lipid-Water Interface.

scientific article

Capsaicin affects the structure and phase organization of phospholipid membranes ⬇️

scientific article published on March 22, 1995

Characterization of ruthenium red-binding sites of the Ca2+-ATPase from sarcoplasmic reticulum and their interaction with Ca2+-binding sites ⬇️

scientific article published on November 1, 1992

Characterization of the membrane binding mode of the C2 domain of PKC epsilon.

scientific article published in October 2003

Correlation between fluorescence and structure in the orange-emitting GFP-like protein, monomeric Kusabira Orange

scientific article

Correlation between protein kinase C alpha activity and membrane phase behavior

scientific article

Correlation between the effect of the anti‐neoplastic ether lipid 1‐O‐octadecyl‐2‐O‐methyl‐glycero‐3‐phosphocholine on the membrane and the activity of protein kinase Cα ⬇️

scientific article published on December 1, 2001

Curcumin disorders 1,2-dipalmitoyl-sn-glycero-3-phosphocholine membranes and favors the formation of nonlamellar structures by 1,2-dielaidoyl-sn-glycero-3-phosphoethanolamine.

scientific article published on August 2010

Curcumin modulates PKCα activity by a membrane-dependent effect

scientific article published on 29 June 2011

Development of Poly(lactide-co-glicolide) Nanoparticles Incorporating Morphine Hydrochloride to Prolong its Circulation in Blood

scientific article published in December 2016

Diacylglycerols as activators of protein kinase C.

scientific article

Diacylglycerols, multivalent membrane modulators.

scientific article published on 19 April 2007

Difference infrared spectroscopy of aqueous model and biological membranes using an infrared data station ⬇️

scientific article published on June 1, 1980

Effect of calcium and phosphatidic acid binding on the C2 domain of PKC alpha as studied by Fourier transform infrared spectroscopy

scientific article published on 01 July 1999

Effects of the anti-neoplastic agent ET-18-OCH3 and some analogs on the biophysical properties of model membranes.

scientific article published on 17 March 2006

Functions of the C-terminal domains of apoptosis-related proteins of the Bcl-2 family.

scientific article published on 02 June 2014

Identification of the phosphatidylserine binding site in the C2 domain that is important for PKC alpha activation and in vivo cell localization.

scientific article

Influence of the physical state of the membrane on the enzymatic activity and energy of activation of protein kinase C alpha

scientific article published on 01 June 1999

Insights into the Impact of a Membrane-Anchoring Moiety on the Biological Activities of Bivalent Compounds As Potential Neuroprotectants for Alzheimer's Disease

scientific article published on 22 December 2017

Interaction of Vitamin K1 and Vitamin K2 with Dimyristoylphosphatidylcholine and Their Location in the Membrane

scientific article published on 23 January 2020

Interaction of the C-terminal domain of Bcl-2 family proteins with model membranes.

scientific article published on 24 August 2007

Interaction of the C2 domain from protein kinase C(epsilon) with model membranes

article

Lamellar gel (lβ) phases of ternary lipid composition containing ceramide and cholesterol.

scientific article published on February 2014

Location of N‐cyclohexyl‐N′‐(4‐dimethyl‐amino‐α‐naphthyl)carbodiimide‐binding site in sarcoplasmic reticulum Ca2+‐transporting ATPase ⬇️

scientific article published on 01 April 1998

Membrane docking mode of the C2 domain of PKCε: an infrared spectroscopy and FRET study.

scientific article

Membrane docking of the C2 domain from protein kinase Cα as seen by polarized ATR-IR. The role of PIP₂.

scientific article

Membrane permeabilization induced by sphingosine: effect of negatively charged lipids

scientific article published on June 2014

Membrane-surface anchoring of charged diacylglycerol-lactones correlates with biological activities

scientific article published on September 2010

Molecular interactions between sphingomyelin and phosphatidylcholine in phospholipid vesicles ⬇️

scientific article published on 01 June 1988

Molecular mechanisms of PKCalpha localization and activation by arachidonic acid. The C2 domain also plays a role.

scientific article published on 25 January 2006

Nanodesign of new self-assembling core-shell gellan-transfersomes loading baicalin and in vivo evaluation of repair response in skin.

scientific article published on 14 December 2017

On the effect of lysophosphatidylcholine, platelet activating factor and other surfactants on calcium permeability in sarcoplasmic reticulum vesicles ⬇️

scientific article published on 01 August 1991

Optimization of Innovative Three-Dimensionally-Structured Hybrid Vesicles to Improve the Cutaneous Delivery of Clotrimazole for the Treatment of Topical Candidiasis

scientific article published on 06 June 2019

Phosphatidylinositol 4,5-bisphosphate decreases the concentration of Ca2+, phosphatidylserine and diacylglycerol required for protein kinase C α to reach maximum activity.

scientific article

Phosphatidylinositol-4,5-bisphosphate enhances anionic lipid demixing by the C2 domain of PKCα

scientific article

Plan S for publishing science in an open access way: not everyone is likely to be happy

scientific article published on 10 November 2019

Retinoic acid binds to the C2-domain of protein kinase C(alpha).

scientific article published in July 2003

Role of the Ca2+/phosphatidylserine binding region of the C2 domain in the translocation of protein kinase Calpha to the plasma membrane.

scientific article published on 13 January 2003

Signaling through C2 domains: more than one lipid target

scientific article

Specificity of nucleotide binding and coupled reactions utilising the mitochondrial ATPase ⬇️

scientific article published on December 7, 1978

Structural Study of the C2 Domains of the Classical PKC Isoenzymes Using Infrared Spectroscopy and Two-Dimensional Infrared Correlation Spectroscopy ⬇️

scientific article published on October 14, 2003

Structural characterization of the Rabphilin-3A-SNAP25 interaction

scientific article published on 20 June 2017

Structural insights into the Ca2+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A and synaptotagmin 1

scientific article

Structural study of the catalytic domain of PKCzeta using infrared spectroscopy and two-dimensional infrared correlation spectroscopy

scientific article published on 19 June 2006

The C1B domains of novel PKCε and PKCη have a higher membrane binding affinity than those of the also novel PKCδ and PKCθ.

scientific article published on 13 April 2014

The C2 domain of PKCalpha is a Ca2+ -dependent PtdIns(4,5)P2 sensing domain: a new insight into an old pathway.

scientific article published on 9 August 2006

The C2 domains of classical PKCs are specific PtdIns(4,5)P2-sensing domains with different affinities for membrane binding

scientific article published on 02 June 2007

The dissimilar effect of diacylglycerols on Ca(2+)-induced phosphatidylserine vesicle fusion ⬇️

scientific article published on February 1, 1995

The increase in positively charged residues in cecropin D-like Galleria mellonella favors its interaction with membrane models that imitate bacterial membranes.

scientific article published on 15 July 2017

The interaction of the Bax C-terminal domain with membranes is influenced by the presence of negatively charged phospholipids.

scientific article

The interaction of the Bax C-terminal domain with negatively charged lipids modifies the secondary structure and changes its way of insertion into membranes

scientific article published on 13 July 2008

The membrane binding kinetics of full-length PKCα is determined by membrane lipid composition

scientific article published on 27 July 2012

The phase behavior of aqueous dispersions of unsaturated mixtures of diacylglycerols and phospholipids

scientific article published on 01 August 1998

The phenolic group of α-tocopherol anchors in the lipid-water interface of fully saturated membranes

scientific article published on 15 February 2018

The structure of the C-terminal domain of the pro-apoptotic protein Bak and its interaction with model membranes.

scientific article

The use of FT-IR for quantitative studies of the apparent pKa of lipid carboxyl groups and the dehydration degree of the phosphate group of phospholipids

scientific article published on 01 November 1998

The vertical location of α-tocopherol in phosphatidylcholine membranes is not altered as a function of the degree of unsaturation of the fatty acyl chains.

scientific article

X-ray diffraction and NMR data for the study of the location of idebenone and idebenol in model membranes.

scientific article

List of works by Juan C. Gómez-Fernández

1,2-Dioleoylglycerol promotes calcium-induced fusion in phospholipid vesicles

A comparative study of the activation of protein kinase C alpha by different diacylglycerol isomers.

A comparison of the membrane binding properties of C1B domains of PKCgamma, PKCdelta, and PKCepsilon.

A kinetic study of the interaction between mitochondrial F1 adenosine triphosphatase and adenylyl imidodiphosphate and guanylyl imidodiphosphate ⬇️

A kinetic study of the interaction of vanadate with the Ca2+ + Mg2+-dependent ATPase from sarcoplasmic reticulum ⬇️

A new phosphatidylinositol 4,5-bisphosphate-binding site located in the C2 domain of protein kinase Calpha.

A study on the interactions of surfactin with phospholipid vesicles

A thermodynamic analysis of the interaction between the mitochondrial coupling adenosine triphosphatase and its naturally occurring inhibitor protein ⬇️

ATP enhances neuronal differentiation of PC12 cells by activating PKCα interactions with cytoskeletal proteins.

Activation of protein kinase C alpha by lipid mixtures containing different proportions of diacylglycerols

Alcohol dehydrogenase from the hyperthermophilic archaeon Pyrobaculum aerophilum: stability at high temperature.

Anticancer Agent Edelfosine Exhibits a High Affinity for Cholesterol and Disorganizes Liquid-Ordered Membrane Structures

Both idebenone and idebenol are localized near the lipid-water interface of the membrane and increase its fluidity

C2 domains of protein kinase C isoforms alpha, beta, and gamma: activation parameters and calcium stoichiometries of the membrane-bound state

Calorimetric Study of the Interaction of the C2 Domains of Classical Protein Kinase C Isoenzymes with Ca2+and Phospholipids†

Capsaicin Fluidifies the Membrane and Localizes Itself near the Lipid-Water Interface.

Capsaicin affects the structure and phase organization of phospholipid membranes ⬇️

Characterization of ruthenium red-binding sites of the Ca2+-ATPase from sarcoplasmic reticulum and their interaction with Ca2+-binding sites ⬇️

Characterization of the membrane binding mode of the C2 domain of PKC epsilon.

Correlation between fluorescence and structure in the orange-emitting GFP-like protein, monomeric Kusabira Orange

Correlation between protein kinase C alpha activity and membrane phase behavior

Correlation between the effect of the anti‐neoplastic ether lipid 1‐O‐octadecyl‐2‐O‐methyl‐glycero‐3‐phosphocholine on the membrane and the activity of protein kinase Cα ⬇️

Curcumin disorders 1,2-dipalmitoyl-sn-glycero-3-phosphocholine membranes and favors the formation of nonlamellar structures by 1,2-dielaidoyl-sn-glycero-3-phosphoethanolamine.

Curcumin modulates PKCα activity by a membrane-dependent effect

Development of Poly(lactide-co-glicolide) Nanoparticles Incorporating Morphine Hydrochloride to Prolong its Circulation in Blood

Diacylglycerols as activators of protein kinase C.

Diacylglycerols, multivalent membrane modulators.

Difference infrared spectroscopy of aqueous model and biological membranes using an infrared data station ⬇️

Effect of calcium and phosphatidic acid binding on the C2 domain of PKC alpha as studied by Fourier transform infrared spectroscopy

Effects of the anti-neoplastic agent ET-18-OCH3 and some analogs on the biophysical properties of model membranes.

Functions of the C-terminal domains of apoptosis-related proteins of the Bcl-2 family.

Identification of the phosphatidylserine binding site in the C2 domain that is important for PKC alpha activation and in vivo cell localization.

Influence of the physical state of the membrane on the enzymatic activity and energy of activation of protein kinase C alpha

Insights into the Impact of a Membrane-Anchoring Moiety on the Biological Activities of Bivalent Compounds As Potential Neuroprotectants for Alzheimer's Disease

Interaction of Vitamin K1 and Vitamin K2 with Dimyristoylphosphatidylcholine and Their Location in the Membrane

Interaction of the C-terminal domain of Bcl-2 family proteins with model membranes.

Interaction of the C2 domain from protein kinase C(epsilon) with model membranes

Lamellar gel (lβ) phases of ternary lipid composition containing ceramide and cholesterol.

Location of N‐cyclohexyl‐N′‐(4‐dimethyl‐amino‐α‐naphthyl)carbodiimide‐binding site in sarcoplasmic reticulum Ca2+‐transporting ATPase ⬇️

Membrane docking mode of the C2 domain of PKCε: an infrared spectroscopy and FRET study.

Membrane docking of the C2 domain from protein kinase Cα as seen by polarized ATR-IR. The role of PIP₂.

Membrane permeabilization induced by sphingosine: effect of negatively charged lipids

Membrane-surface anchoring of charged diacylglycerol-lactones correlates with biological activities

Molecular interactions between sphingomyelin and phosphatidylcholine in phospholipid vesicles ⬇️

Molecular mechanisms of PKCalpha localization and activation by arachidonic acid. The C2 domain also plays a role.

Nanodesign of new self-assembling core-shell gellan-transfersomes loading baicalin and in vivo evaluation of repair response in skin.

On the effect of lysophosphatidylcholine, platelet activating factor and other surfactants on calcium permeability in sarcoplasmic reticulum vesicles ⬇️

Optimization of Innovative Three-Dimensionally-Structured Hybrid Vesicles to Improve the Cutaneous Delivery of Clotrimazole for the Treatment of Topical Candidiasis

Phosphatidylinositol 4,5-bisphosphate decreases the concentration of Ca2+, phosphatidylserine and diacylglycerol required for protein kinase C α to reach maximum activity.

Phosphatidylinositol-4,5-bisphosphate enhances anionic lipid demixing by the C2 domain of PKCα

Plan S for publishing science in an open access way: not everyone is likely to be happy

Retinoic acid binds to the C2-domain of protein kinase C(alpha).

Role of the Ca2+/phosphatidylserine binding region of the C2 domain in the translocation of protein kinase Calpha to the plasma membrane.

Signaling through C2 domains: more than one lipid target

Specificity of nucleotide binding and coupled reactions utilising the mitochondrial ATPase ⬇️

Structural Study of the C2 Domains of the Classical PKC Isoenzymes Using Infrared Spectroscopy and Two-Dimensional Infrared Correlation Spectroscopy ⬇️

Structural characterization of the Rabphilin-3A-SNAP25 interaction

Structural insights into the Ca2+ and PI(4,5)P2 binding modes of the C2 domains of rabphilin 3A and synaptotagmin 1

Structural study of the catalytic domain of PKCzeta using infrared spectroscopy and two-dimensional infrared correlation spectroscopy

The C1B domains of novel PKCε and PKCη have a higher membrane binding affinity than those of the also novel PKCδ and PKCθ.

The C2 domain of PKCalpha is a Ca2+ -dependent PtdIns(4,5)P2 sensing domain: a new insight into an old pathway.

The C2 domains of classical PKCs are specific PtdIns(4,5)P2-sensing domains with different affinities for membrane binding

The dissimilar effect of diacylglycerols on Ca(2+)-induced phosphatidylserine vesicle fusion ⬇️

The increase in positively charged residues in cecropin D-like Galleria mellonella favors its interaction with membrane models that imitate bacterial membranes.

The interaction of the Bax C-terminal domain with membranes is influenced by the presence of negatively charged phospholipids.

The interaction of the Bax C-terminal domain with negatively charged lipids modifies the secondary structure and changes its way of insertion into membranes

The membrane binding kinetics of full-length PKCα is determined by membrane lipid composition

The phase behavior of aqueous dispersions of unsaturated mixtures of diacylglycerols and phospholipids

The phenolic group of α-tocopherol anchors in the lipid-water interface of fully saturated membranes

The structure of the C-terminal domain of the pro-apoptotic protein Bak and its interaction with model membranes.

The use of FT-IR for quantitative studies of the apparent pKa of lipid carboxyl groups and the dehydration degree of the phosphate group of phospholipids

The vertical location of α-tocopherol in phosphatidylcholine membranes is not altered as a function of the degree of unsaturation of the fatty acyl chains.

X-ray diffraction and NMR data for the study of the location of idebenone and idebenol in model membranes.