Search filters

List of works by G. Vignir Helgason

A randomised phase II trial of hydroxychloroquine and imatinib versus imatinib alone for patients with chronic myeloid leukaemia in major cytogenetic response with residual disease

scientific article published on 10 January 2020

ATG7 regulates energy metabolism, differentiation and survival of Philadelphia-chromosome-positive cells

scientific article published on 11 May 2016

Auto-Commentary on: "Targeting mitochondrial oxidative phosphorylation eradicates therapy-resistant chronic myeloid leukemia stem cells".

scientific article published on 18 December 2017

Autophagy and mitochondrial metabolism: insights into their role and therapeutic potential in chronic myeloid leukaemia

scientific article published on 08 October 2018

Autophagy in blood cancers: biological role and therapeutic implications.

scientific article published on September 2013

Autophagy in chronic myeloid leukaemia: stem cell survival and implication in therapy

scientific article published on September 2013

Axl Blockade by BGB324 Inhibits BCR-ABL Tyrosine Kinase Inhibitor-Sensitive and -Resistant Chronic Myeloid Leukemia

scientific article published on 17 November 2016

BCR signaling contributes to autophagy regulation in chronic lymphocytic leukemia

scientific article published on 28 August 2019

Chronic myeloid leukemia stem cells are not dependent on Bcr-Abl kinase activity for their survival

scientific article published on 19 December 2011

Combined BCR-ABL inhibition with lentiviral-delivered shRNA and dasatinib augments induction of apoptosis in Philadelphia-positive cells

scientific article

Do we need more drugs for chronic myeloid leukemia?

scientific article

FOXO transcription factor activity is partially retained in quiescent CML stem cells and induced by tyrosine kinase inhibitors in CML progenitor cells

scientific article published in December 2009

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

article by Daniel J Klionsky et al published January 2021 in Autophagy

Hsa-mir183/EGR1-mediated regulation of E2F1 is required for CML stem/progenitor cell survival.

scientific article published on 5 February 2018

Hydroxychloroquine for chronic myeloid leukemia: complete cure on the horizon?

scientific article

Kill one bird with two stones: potential efficacy of BCR-ABL and autophagy inhibition in CML.

scientific article published on 21 June 2011

Mechanisms and novel approaches in overriding tyrosine kinase inhibitor resistance in chronic myeloid leukemia

scientific article published on March 2012

Mtss1 is a critical epigenetically regulated tumor suppressor in CML.

scientific article published on December 2015

Oncogene-induced sensitization to chemotherapy-induced death requires induction as well as deregulation of E2F1.

scientific article published on 11 May 2010

Role of autophagy in cancer prevention, development and therapy

scientific article published on January 2013

Targeting BCR-ABL-Independent TKI Resistance in Chronic Myeloid Leukemia by mTOR and Autophagy Inhibition

scientific article published on 20 November 2017

Targeting autophagy potentiates tyrosine kinase inhibitor-induced cell death in Philadelphia chromosome-positive cells, including primary CML stem cells

scientific article published on 13 April 2009

Targeting autophagy potentiates tyrosine kinaseinhibitor–induced cell death in Philadelphia chromosome–positivecells, including primary CML stem cells.

scientific article

Targeting chronic myeloid leukemia stem cells

scientific article published on April 2010

Targeting mitochondrial oxidative phosphorylation eradicates therapy-resistant chronic myeloid leukemia stem cells

scientific article published on 18 September 2017

Targeting quiescent leukemic stem cells using second generation autophagy inhibitors

scientific article published on 05 September 2018

The Ins and Outs of Autophagy and Metabolism in Hematopoietic and Leukemic Stem Cells: Food for Thought

scientific article published on 26 September 2018

The MEK inhibitor PD184352 enhances BMS-214662-induced apoptosis in CD34+ CML stem/progenitor cells

scientific article published on 12 April 2011

The antiproliferative activity of kinase inhibitors in chronic myeloid leukemia cells is mediated by FOXO transcription factors

scientific article

The leukaemia stem cell: similarities, differences and clinical prospects in CML and AML

scientific article published on 06 January 2020