List of works by Carla Mellough

3D culture of human pluripotent stem cells in RGD-alginate hydrogel improves retinal tissue development.

scientific article published on 4 November 2016

A Review of Gene, Drug and Cell-Based Therapies for Usher Syndrome

scientific article published on 09 July 2020

An Induced Pluripotent Stem Cell Patient Specific Model of Complement Factor H (Y402H) Polymorphism Displays Characteristic Features of Age-Related Macular Degeneration and Indicates a Beneficial Role for UV Light Exposure. ⬇️

scientific article published on 15 September 2017

An integrated transcriptional analysis of the developing human retina

scientific article published on 29 January 2019

Analysis of human ES cell differentiation establishes that the dominant isoforms of the lncRNAs RMST and FIRRE are circular.

scientific article

Efficient stage-specific differentiation of human pluripotent stem cells toward retinal photoreceptor cells.

scientific article published on April 2012

Extracellular matrix component expression in human pluripotent stem cell-derived retinal organoids recapitulates retinogenesis in vivo and reveals an important role for IMPG1 and CD44 in the development of photoreceptors and interphotoreceptor matri

scientific article published on 17 May 2018

Fate of multipotent neural precursor cells transplanted into mouse retina selectively depleted of retinal ganglion cells.

scientific article published in March 2004

Gelsolin dysfunction causes photoreceptor loss in induced pluripotent cell and animal retinitis pigmentosa models.

scientific article published on 16 August 2017

Gene therapy and transplantation in CNS repair: the visual system.

scientific article published on 11 September 2006

Genetic basis of inherited macular dystrophies and implications for stem cell therapy.

scientific article

How to build a human

scientific article published on 24 August 2016

IGF-1 Signaling Plays an Important Role in the Formation of Three-Dimensional Laminated Neural Retina and Other Ocular Structures From Human Embryonic Stem Cells.

scientific article

Lab generated retina: realizing the dream.

scientific article published on 22 May 2014

Laminin γ3 plays an important role in retinal lamination, photoreceptor organisation and ganglion cell differentiation.

scientific article

Postmitotic Cone Migration Mechanisms in the Mammalian Retina

scientific article published on 01 January 2019

Systematic Comparison of Retinal Organoid Differentiation from Human Pluripotent Stem Cells Reveals Stage Specific, Cell Line, and Methodological Differences

scientific article published on 27 March 2019

Use of induced pluripotent stem-cell technology to understand photoreceptor cytoskeletal dynamics in retinitis pigmentosa.

scientific article

Using Zinc Finger Nuclease Technology to Generate CRX-Reporter Human Embryonic Stem Cells as a Tool to Identify and Study the Emergence of Photoreceptors Precursors During Pluripotent Stem Cell Differentiation.

scientific article published on 26 November 2015

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