List of works - Feng Zhu

3,6,2',4',5'-Pentahydroxyflavone, an orally bioavailable multiple protein kinase inhibitor, overcomes gefitinib resistance in non-small cell lung cancer

scientific article

6-C-(E-phenylethenyl)-naringenin suppresses colorectal cancer growth by inhibiting cyclooxygenase-1.

scientific article

Antioxidants decrease the apoptotic effect of 5-Fu in colon cancer by regulating Src-dependent caspase-7 phosphorylation

scientific article

Apoptosis-related genes cloned by improved subtractive hybridization

scientific article published in May 2001

Aspirin Prevents Colorectal Cancer by Normalizing EGFR Expression

scientific article published on May 2015

Ataxia telangiectasia mutated proteins, MAPKs, and RSK2 are involved in the phosphorylation of STAT3.

scientific article

BCKDK of BCAA Catabolism Cross-talking With the MAPK Pathway Promotes Tumorigenesis of Colorectal Cancer

scientific article

Bidirectional signals transduced by TOPK-ERK interaction increase tumorigenesis of HCT116 colorectal cancer cells

scientific article (publication date: July 2007)

COOH-terminal Src kinase-mediated c-Jun phosphorylation promotes c-Jun degradation and inhibits cell transformation.

scientific article

Caffeic acid directly targets ERK1/2 to attenuate solar UV-induced skin carcinogenesis.

scientific article

Cefradine blocks solar-ultraviolet induced skin inflammation through direct inhibition of T-LAK cell-originated protein kinase.

scientific article published on 22 March 2016

Cell apoptosis: requirement of H2AX in DNA ladder formation, but not for the activation of caspase-3.

scientific article published on July 2006

Cyclin-dependent kinase-3-mediated c-Jun phosphorylation at Ser63 and Ser73 enhances cell transformation.

scientific article published on January 2009

Dasatinib reduces 5-Fu-triggered apoptosis in colon carcinoma by directly modulating Src-dependent caspase-9 phosphorylation.

scientific article

Direct inhibition of insulin-like growth factor-I receptor kinase activity by (-)-epigallocatechin-3-gallate regulates cell transformation

scientific article published on 01 March 2007

Discovery of the novel mTOR inhibitor and its antitumor activities in vitro and in vivo

scientific article published on 27 March 2013

Identification of an Aurora kinase inhibitor specific for the Aurora B isoform.

scientific article

Improved PCR-based subtractive hybridization strategy for cloning differentially expressed genes

scientific article

Inhibiting breast cancer by targeting the thromboxane A2 pathway.

scientific article published on 3 April 2017

Knockdown of RNF2 induces apoptosis by regulating MDM2 and p53 stability.

scientific article published on 14 January 2013

Lymphokine-activated killer T-cell-originated protein kinase phosphorylation of histone H2AX prevents arsenite-induced apoptosis in RPMI7951 melanoma cells.

scientific article

MST1 promotes apoptosis through phosphorylation of histone H2AX

scientific article

Meningeal Ewing Sarcoma/Peripheral PNET: Clinicopathological, Immunohistochemical and FISH study of four cases.

scientific article

Norathyriol Suppresses Skin Cancers Induced by Solar Ultraviolet Radiation by Targeting ERK Kinases

scientific article

PDZ-binding kinase/T-LAK cell-originated protein kinase is a target of the fucoidan from brown alga Fucus evanescens in the prevention of EGF-induced neoplastic cell transformation and colon cancer growth

scientific article published on 25 February 2016

PRIMA-1Met suppresses colorectal cancer independent of p53 by targeting MEK

scientific article published on 27 October 2016

Paeonol suppresses solar ultraviolet-induced skin inflammation by targeting T-LAK cell-originated protein kinase

scientific article

Pantoprazole, an FDA-approved proton-pump inhibitor, suppresses colorectal cancer growth by targeting T-cell-originated protein kinase.

scientific article published on 08 March 2016

Phosphorylation of H2AX at Ser139 and a new phosphorylation site Ser16 by RSK2 decreases H2AX ubiquitination and inhibits cell transformation

scientific article published on 11 January 2011

Phosphorylation of Ser28 in histone H3 mediated by mixed lineage kinase-like mitogen-activated protein triple kinase alpha

scientific article

Phosphorylation of TOPK at Y74, Y272 by Src increases the stability of TOPK and promotes tumorigenesis of colon

scientific article published on 21 March 2016

Phosphorylation of caspase-7 by p21-activated protein kinase (PAK) 2 inhibits chemotherapeutic drug-induced apoptosis of breast cancer cell lines

scientific article

Phosphorylation of caspase-8 (Thr-263) by ribosomal S6 kinase 2 (RSK2) mediates caspase-8 ubiquitination and stability.

scientific article

Phosphorylation of histone H2B serine 32 is linked to cell transformation.

scientific article

Protein kinases as tumor biomarkers and therapeutic targets.

scientific article

Quercetin-3-methyl ether suppresses proliferation of mouse epidermal JB6 P+ cells by targeting ERKs.

scientific article published on December 2011

RSK2 mediates NF-{kappa}B activity through the phosphorylation of IkappaBalpha in the TNF-R1 pathway.

scientific article

Resveratrol directly targets COX-2 to inhibit carcinogenesis.

scientific article published on October 2008

Salidroside suppresses solar ultraviolet-induced skin inflammation by targeting cyclooxygenase-2

scientific article published on 23 March 2016

Select dietary phytochemicals function as inhibitors of COX-1 but not COX-2

scientific article

T-LAK cell-originated protein kinase (TOPK) phosphorylation of MKP1 protein prevents solar ultraviolet light-induced inflammation through inhibition of the p38 protein signaling pathway

scientific journal article

T-lymphokine-activated killer cell-originated protein kinase (TOPK) as a prognostic factor and a potential therapeutic target in glioma.

scientific article published on 26 December 2017

TRAF4 is a critical molecule for Akt activation in lung cancer.

scientific article published on 23 October 2013

Targeting PRPK Function Blocks Colon Cancer Metastasis.

scientific article published on 26 February 2018

Targeting PRPK and TOPK for skin cancer prevention and therapy

scientific article published on 14 June 2018

The T-LAK Cell-originated Protein Kinase Signal Pathway Promotes Colorectal Cancer Metastasis

scientific article

The cannabinoid receptors are required for ultraviolet-induced inflammation and skin cancer development

scientific article published on May 2008

The p53 protein is a novel substrate of ribosomal S6 kinase 2 and a critical intermediary for ribosomal S6 kinase 2 and histone H3 interaction.

scientific article

The signal transduction networks required for phosphorylation of STAT1 at Ser727 in mouse epidermal JB6 cells in the UVB response and inhibitory mechanisms of tea polyphenols.

scientific article

Theaflavin-3, 3'-digallate induces epidermal growth factor receptor downregulation.

scientific article

Transient receptor potential type vanilloid 1 suppresses skin carcinogenesis.

scientific article published on 20 January 2009

[Cloning and subcellular localization of apr-1--a new gene of tumor specific antigen family]

scientific article published on 01 February 2005

[The expression and mechanism study of BMP in pleomorphic adenoma]

scientific article published on 01 April 2000

List of works by Feng Zhu

3,6,2',4',5'-Pentahydroxyflavone, an orally bioavailable multiple protein kinase inhibitor, overcomes gefitinib resistance in non-small cell lung cancer

6-C-(E-phenylethenyl)-naringenin suppresses colorectal cancer growth by inhibiting cyclooxygenase-1.

Antioxidants decrease the apoptotic effect of 5-Fu in colon cancer by regulating Src-dependent caspase-7 phosphorylation

Apoptosis-related genes cloned by improved subtractive hybridization

Aspirin Prevents Colorectal Cancer by Normalizing EGFR Expression

Ataxia telangiectasia mutated proteins, MAPKs, and RSK2 are involved in the phosphorylation of STAT3.

BCKDK of BCAA Catabolism Cross-talking With the MAPK Pathway Promotes Tumorigenesis of Colorectal Cancer

Bidirectional signals transduced by TOPK-ERK interaction increase tumorigenesis of HCT116 colorectal cancer cells

COOH-terminal Src kinase-mediated c-Jun phosphorylation promotes c-Jun degradation and inhibits cell transformation.

Caffeic acid directly targets ERK1/2 to attenuate solar UV-induced skin carcinogenesis.

Cefradine blocks solar-ultraviolet induced skin inflammation through direct inhibition of T-LAK cell-originated protein kinase.

Cell apoptosis: requirement of H2AX in DNA ladder formation, but not for the activation of caspase-3.

Cyclin-dependent kinase-3-mediated c-Jun phosphorylation at Ser63 and Ser73 enhances cell transformation.

Dasatinib reduces 5-Fu-triggered apoptosis in colon carcinoma by directly modulating Src-dependent caspase-9 phosphorylation.

Direct inhibition of insulin-like growth factor-I receptor kinase activity by (-)-epigallocatechin-3-gallate regulates cell transformation

Discovery of the novel mTOR inhibitor and its antitumor activities in vitro and in vivo

Identification of an Aurora kinase inhibitor specific for the Aurora B isoform.

Improved PCR-based subtractive hybridization strategy for cloning differentially expressed genes

Inhibiting breast cancer by targeting the thromboxane A2 pathway.

Knockdown of RNF2 induces apoptosis by regulating MDM2 and p53 stability.

Lymphokine-activated killer T-cell-originated protein kinase phosphorylation of histone H2AX prevents arsenite-induced apoptosis in RPMI7951 melanoma cells.

MST1 promotes apoptosis through phosphorylation of histone H2AX

Meningeal Ewing Sarcoma/Peripheral PNET: Clinicopathological, Immunohistochemical and FISH study of four cases.

Norathyriol Suppresses Skin Cancers Induced by Solar Ultraviolet Radiation by Targeting ERK Kinases

PDZ-binding kinase/T-LAK cell-originated protein kinase is a target of the fucoidan from brown alga Fucus evanescens in the prevention of EGF-induced neoplastic cell transformation and colon cancer growth

PRIMA-1Met suppresses colorectal cancer independent of p53 by targeting MEK

Paeonol suppresses solar ultraviolet-induced skin inflammation by targeting T-LAK cell-originated protein kinase

Pantoprazole, an FDA-approved proton-pump inhibitor, suppresses colorectal cancer growth by targeting T-cell-originated protein kinase.

Phosphorylation of H2AX at Ser139 and a new phosphorylation site Ser16 by RSK2 decreases H2AX ubiquitination and inhibits cell transformation

Phosphorylation of Ser28 in histone H3 mediated by mixed lineage kinase-like mitogen-activated protein triple kinase alpha

Phosphorylation of TOPK at Y74, Y272 by Src increases the stability of TOPK and promotes tumorigenesis of colon

Phosphorylation of caspase-7 by p21-activated protein kinase (PAK) 2 inhibits chemotherapeutic drug-induced apoptosis of breast cancer cell lines

Phosphorylation of caspase-8 (Thr-263) by ribosomal S6 kinase 2 (RSK2) mediates caspase-8 ubiquitination and stability.

Phosphorylation of histone H2B serine 32 is linked to cell transformation.

Protein kinases as tumor biomarkers and therapeutic targets.

Quercetin-3-methyl ether suppresses proliferation of mouse epidermal JB6 P+ cells by targeting ERKs.

RSK2 mediates NF-{kappa}B activity through the phosphorylation of IkappaBalpha in the TNF-R1 pathway.

Resveratrol directly targets COX-2 to inhibit carcinogenesis.

Salidroside suppresses solar ultraviolet-induced skin inflammation by targeting cyclooxygenase-2

Select dietary phytochemicals function as inhibitors of COX-1 but not COX-2

T-LAK cell-originated protein kinase (TOPK) phosphorylation of MKP1 protein prevents solar ultraviolet light-induced inflammation through inhibition of the p38 protein signaling pathway

T-lymphokine-activated killer cell-originated protein kinase (TOPK) as a prognostic factor and a potential therapeutic target in glioma.

TRAF4 is a critical molecule for Akt activation in lung cancer.

Targeting PRPK Function Blocks Colon Cancer Metastasis.

Targeting PRPK and TOPK for skin cancer prevention and therapy

The T-LAK Cell-originated Protein Kinase Signal Pathway Promotes Colorectal Cancer Metastasis

The cannabinoid receptors are required for ultraviolet-induced inflammation and skin cancer development

The p53 protein is a novel substrate of ribosomal S6 kinase 2 and a critical intermediary for ribosomal S6 kinase 2 and histone H3 interaction.

The signal transduction networks required for phosphorylation of STAT1 at Ser727 in mouse epidermal JB6 cells in the UVB response and inhibitory mechanisms of tea polyphenols.

Theaflavin-3, 3'-digallate induces epidermal growth factor receptor downregulation.

Transient receptor potential type vanilloid 1 suppresses skin carcinogenesis.

[Cloning and subcellular localization of apr-1--a new gene of tumor specific antigen family]

[The expression and mechanism study of BMP in pleomorphic adenoma]