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List of works by Adam Jarmuła

5,10-Methylene-5,6,7,8-tetrahydrofolate conformational transitions upon binding to thymidylate synthase: molecular mechanics and continuum solvent studies

scientific article published on February 2005

A molecular modeling study of the interaction of 2'-fluoro-substituted analogues of dUMP/FdUMP with thymidylate synthase.

scientific article

ANO5 mutations in the Polish limb girdle muscular dystrophy patients: Effects on the protein structure

scientific article published on 08 August 2019

Antifolate inhibitors of thymidylate synthase as anticancer drugs

scientific article

Combining Rosetta with molecular dynamics (MD): A benchmark of the MD-based ensemble protein design

scientific article published on 14 February 2018

Computational study of the effects of protein tyrosine nitrations on the catalytic activity of human thymidylate synthase

scientific article published on 13 December 2012

Crystal Structure of Mouse Thymidylate Synthase in Tertiary Complex with dUMP and Raltitrexed Reveals N-Terminus Architecture and Two Different Active Site Conformations

scientific article

Crystal structure of phosphoramide-phosphorylated thymidylate synthase reveals pSer127, reflecting probably pHis to pSer phosphotransfer

scientific article

Crystal structures of 5-fluoro-dUrd and its 2 and/or 4-thio analogues: models of substituted dUMP pyrimidine ring interacting with thymidylate synthase

scientific article published on 01 February 1998

Crystal structures of nematode (parasitic T. spiralis and free living C. elegans), compared to mammalian, thymidylate synthases (TS). Molecular docking and molecular dynamics simulations in search for nematode-specific inhibitors of TS.

scientific article published on 12 August 2017

Different Activities of 5-Hydroxy-dUMP and 5-Hydroxymethyl-dUMP in Thymidylate Synthase-Catalyzed Reaction in View of Molecular Modeling and Structural Studies

scientific article published on 01 June 2000

Human dihydrofolate reductase and thymidylate synthase form a complex in vitro and co-localize in normal and cancer cells.

scientific article published on 17 May 2016

Interactions between motor domains in kinesin-14 Ncd - a molecular dynamics study

scientific article published on 10 September 2019

Mechanism of influence of phosphorylation on serine 124 on a decrease of catalytic activity of human thymidylate synthase

scientific article published on 9 April 2010

Mouse thymidylate synthase does not show the inactive conformation, observed for the human enzyme

Phosphorylation of thymidylate synthase affects slow-binding inhibition by 5-fluoro-dUMP and N(4)-hydroxy-dCMP.

scientific article

Properties of phosphorylated thymidylate synthase

scientific journal article

Relative free energies of binding to thymidylate synthase of 2- and/or 4-thio and/or 5-fluoro analogues of dUMP.

scientific article published in October 2003

Synthesis and interactions with thymidylate synthase of 2,4-dithio analogues of dUMP and 5-fluoro-dUMP

scientific article published on 01 March 1996

The aromaticity of 5,6-dihydroborauracil, borauracil and benzoborauracil systems.

scientific article published on July 2010

The effect of 5-substitution in the pyrimidine ring of dUMP on the interaction with thymidylate synthase: molecular modeling and QSAR

scientific article published on 19 January 2007

The β-sheet breakers and π-stacking

scientific article published on 25 March 2013

Tyrosine nitration affects thymidylate synthase properties.

scientific article

[Thymidylate synthase-catalyzed reaction mechanism].

scientific article published in January 2015

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