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List of works by Amanda Swain

Adrenal development is initiated by Cited2 and Wt1 through modulation of Sf-1 dosage

scientific article

Brca2 and Trp53 deficiency cooperate in the progression of mouse prostate tumourigenesis

scientific article (publication date: June 2010)

CHD1 loss sensitizes prostate cancer to DNA damaging therapy by promoting error-prone double-strand break repair.

scientific article published on 5 April 2017

DNA-Repair Defects and Olaparib in Metastatic Prostate Cancer ⬇️

scientific article

Dax1 antagonizes Sry action in mammalian sex determination

scientific journal article

Developmental genetics. Too much sex is bad for males

scientific article published in November 1998

Ductal sex determination.

scientific article published in August 2017

Follistatin operates downstream of Wnt4 in mammalian ovary organogenesis

scientific journal article

Gene dosage effects and transcriptional regulation of early mammalian adrenal cortex development.

scientific article published on 16 December 2009

Genome-wide and high-density CRISPR-Cas9 screens identify point mutations in PARP1 causing PARP inhibitor resistance.

scientific article published on 10 May 2018

Genome-wide barcoded transposon screen for cancer drug sensitivity in haploid mouse embryonic stem cells

scientific article

HOX genes promote cell proliferation and are potential therapeutic targets in adrenocortical tumours

scientific article published on 20 November 2020

High-Level Clonal FGFR Amplification and Response to FGFR Inhibition in a Translational Clinical Trial

scientific article published on 13 May 2016

Identification of a novel population of adrenal-like cells in the mammalian testis

scientific article published on 31 July 2006

In vivo evidence for the crucial role of SF1 in steroid-producing cells of the testis, ovary and adrenal gland ⬇️

scientific article published on November 7, 2012

Mechanisms of Disease: normal and abnormal gonadal development and sex determination in mammals.

scientific article

Prostate Organogenesis.

scientific article published on 11 December 2017

Pten Regulates Epithelial Cytodifferentiation during Prostate Development

scientific article published on 15 June 2015

SOX9 elevation in the prostate promotes proliferation and cooperates with PTEN loss to drive tumor formation

scientific article

SOX9 is a driver of aggressive prostate cancer by promoting invasion, cell fate and cytoskeleton alterations and epithelial to mesenchymal transition

scientific article published on 10 January 2018

Sex determination: time for meiosis? The gonad decides.

scientific article published in July 2006

Sex specific retinoic acid signaling is required for the initiation of urogenital sinus bud development.

scientific article

Sox9 is required for prostate development

scientific journal article

Targeting Bromodomain and Extra-Terminal (BET) Family Proteins in Castration-Resistant Prostate Cancer (CRPC).

scientific article published on 19 March 2018

The role of Sox9 in prostate development

scientific article published on 28 June 2008

The transcription co-factor CITED2 functions during sex determination and early gonad development

scientific journal article

Up-regulation of WNT-4 signaling and dosage-sensitive sex reversal in humans.

scientific article

Whole-exome DNA sequence analysis of Brca2- and Trp53-deficient mouse mammary gland tumours

scientific article published on 2 April 2015

Wnt4 participates in the formation of vertebrate neuromuscular junction

scientific article published on 12 January 2012

Wnt4/β-Catenin Signaling Induces VSMC Proliferation and Is Associated With Intimal Thickening

scientific article published on 30 December 2010

β-catenin is required for prostate development and cooperates with Pten loss to drive invasive carcinoma

scientific article

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