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List of works by Ian Roberts

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Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trial

scientific article
Predicting outcome after traumatic brain injury: practical prognostic models based on large cohort of international patients

scientific article published on 12 February 2008
The importance of early treatment with tranexamic acid in bleeding trauma patients: An exploratory analysis of the CRASH-2 randomised controlled trial

scientific article published on March 2011
Effect of intravenous corticosteroids on death within 14 days in 10008 adults with clinically significant head injury (MRC CRASH trial): randomised placebo-controlled trial

scientific article published in October 2004
Final results of MRC CRASH, a randomised placebo-controlled trial of intravenous corticosteroid in adults with head injury-outcomes at 6 months

scientific article published in June 2005
Patient outcome after traumatic brain injury in high-, middle- and low-income countries: analysis of data on 8927 patients in 46 countries

scientific article
The WOMAN Trial (World Maternal Antifibrinolytic Trial): tranexamic acid for the treatment of postpartum haemorrhage: an international randomised, double blind placebo controlled trial

scientific article
Effect of consent rituals on mortality in emergency care research

scientific article published in March 2011
CRASH-3 - tranexamic acid for the treatment of significant traumatic brain injury: study protocol for an international randomized, double-blind, placebo-controlled trial

scientific article published on 21 June 2012
Cost-effectiveness analysis of administering tranexamic acid to bleeding trauma patients using evidence from the CRASH-2 trial

scientific article
Effect of tranexamic acid on mortality in patients with traumatic bleeding: prespecified analysis of data from randomised controlled trial

scientific article (publication date: 11 September 2012)
Anti-fibrinolytic agents in post partum haemorrhage: a systematic review

scientific article published on 15 July 2009
Avoidable mortality from giving tranexamic acid to bleeding trauma patients: an estimation based on WHO mortality data, a systematic literature review and data from the CRASH-2 trial

scientific article
Antifibrinolytic drugs for acute traumatic injury

scientific article published on 19 January 2011
Effect of treatment delay on the effectiveness and safety of antifibrinolytics in acute severe haemorrhage: a meta-analysis of individual patient-level data from 40 138 bleeding patients

scientific article published on 7 November 2017
HALT-IT--tranexamic acid for the treatment of gastrointestinal bleeding: study protocol for a randomised controlled trial

scientific article published on 19 November 2014
Predicting early death in patients with traumatic bleeding: development and validation of prognostic model

scientific article published on 15 August 2012
Marketing and clinical trials: a case study

scientific article
Covariate adjustment increased power in randomized controlled trials: an example in traumatic brain injury

scientific article published on 9 December 2011
The BRAIN TRIAL: a randomised, placebo controlled trial of a Bradykinin B2 receptor antagonist (Anatibant) in patients with traumatic brain injury

scientific article published on 3 December 2009
Haemostatic drugs for traumatic brain injury

scientific article
Trauma care research and the war on uncertainty

scientific article published on November 2005
Prognosis following head injury: a survey of doctors from developing and developed countries

scientific article published in June 2007
Central and statistical data monitoring in the Clinical Randomisation of an Antifibrinolytic in Significant Haemorrhage (CRASH-2) trial

scientific article published on 17 December 2013
Tranexamic acid for significant traumatic brain injury (The CRASH-3 trial): Statistical analysis plan for an international, randomised, double-blind, placebo-controlled trial

scientific article published in 2018
Hydroxyethyl starch solutions and patient harm

scientific article published on 12 February 2018
The effect of tranexamic acid on the risk of death and hysterectomy in women with post-partum haemorrhage: statistical analysis plan for the WOMAN trial

scientific article
A promise to save 100 000 trauma patients

scientific article published on December 15, 2012
Comparison of routes for achieving parenteral access with a focus on the management of patients with Ebola virus disease

scientific article
Use of the Oxford Handicap Scale at hospital discharge to predict Glasgow Outcome Scale at 6 months in patients with traumatic brain injury

scientific article published on 6 November 2008
A nested mechanistic sub-study into the effect of tranexamic acid versus placebo on intracranial haemorrhage and cerebral ischaemia in isolated traumatic brain injury: study protocol for a randomised controlled trial (CRASH-3 Trial Intracranial Blee

scientific article published on 17 July 2017
Tranexamic acid for treatment of women with post-partum haemorrhage in Nigeria and Pakistan: a cost-effectiveness analysis of data from the WOMAN trial

scientific article published in February 2018
Tranexamic acid in bleeding trauma patients: an exploration of benefits and harms

scientific article published on 31 January 2017
Does tranexamic acid improve outcomes in traumatic brain injury?

scientific article published on 28 September 2016
Study protocol for statin web-based investigation of side effects (StatinWISE): a series of randomised controlled N-of-1 trials comparing atorvastatin and placebo in UK primary care

scientific article published in December 2017
Risk factors for peripartum hysterectomy among women with postpartum haemorrhage: analysis of data from the WOMAN trial.

scientific article published on 29 May 2018
Effects of tranexamic acid on platelet function and thrombin generation (ETAPlaT): WOMAN trial sub-study

scientific article (publication date: 15 December 2016)
Clinical trials in emergency situations

scientific article published on January 2007
Haematological and fibrinolytic status of Nigerian women with post-partum haemorrhage.

scientific article published on 9 May 2018
Guide to the design and review of emergency research when it is proposed that consent and consultation be waived

scientific article published on 31 July 2014
Effect of tranexamic acid on coagulation and fibrinolysis in women with postpartum haemorrhage (WOMAN-ETAC): protocol and statistical analysis plan for a randomized controlled trial.

scientific article published on 16 December 2016
Statistical analysis plan for the WOMAN-ETAPlaT study: Effect of tranexamic acid on platelet function and thrombin generation

scientific article published on 15 December 2016
Tranexamic acid for the prevention of postpartum bleeding in women with anaemia: study protocol for an international, randomised, double-blind, placebo-controlled trial

scientific article published on 29 December 2018
Tranexamic acid in trauma: we need stronger global health policy

scientific article published on 23 July 2013
Comparison of routes for achieving parenteral access with a focus on the management of patients with Ebola Virus Disease

scientific article (published 2014-11-17)
Effect of tranexamic acid on coagulation and fibrinolysis in women with postpartum haemorrhage (WOMAN-ETAC): a single-centre, randomised, double-blind, placebo-controlled trial

scientific article published on 15 August 2018
Trial management: we need a cadre of high-class triallists to deliver the answers that patients need

scientific article
No effect of tranexamic acid on platelet function and thrombin generation (ETAPlaT) in postpartum haemorrhage: a randomised placebo-controlled trial

scientific article published on 5 February 2019
The impact of early outcome events on the effect of tranexamic acid in post-partum haemorrhage: an exploratory subgroup analysis of the WOMAN trial

scientific article published on 7 June 2018
Post-partum haemorrhage and tranexamic acid: a global issue

scientific article published on 9 January 2018

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