List of works - Dominic J Campopiano

A novel protein-mineral interface

scientific article (publication date: April 2003)

A putative gene cluster for aminoarabinose biosynthesis is essential for Burkholderia cenocepacia viability

scientific article

ACP-AasS you like it.

scientific article published in October 2014

An improved racemase/acylase biotransformation for the preparation of enantiomerically pure amino acids

scientific article

An investigation of flavoprotein redox partners

scientific article published on 01 August 1998

Analysis and separation of residues important for the chemoattractant and antimicrobial activities of beta-defensin 3.

scientific article published on 7 January 2008

Antimicrobial activity of CHIR-090, an inhibitor of lipopolysaccharide biosynthesis, against the Burkholderia cepacia complex

scientific article published on June 2010

Assembly of an Oxo-Zirconium(IV) Cluster in a Protein Cleft

scientific article published on 01 November 2004

Binding a heparin derived disaccharide to defensin inspired peptides: insights to antimicrobial inhibition from gas-phase measurements

scientific article published on 06 March 2010

Biotinylation in the hyperthermophile Aquifex aeolicus

scientific article published in March 2003

Bivalent enzyme inhibitors discovered using dynamic covalent chemistry

scientific article

Characterisation of 8-amino-7-oxononanoate synthase: A bacterial PLP-dependent, acyl CoA condensing enzyme

scientific article published on 01 August 1998

Characterisation of DEFB107 by mass spectrometry: Lessons from an anti-antimicrobial defensin

article

Characterisation of ferredoxin (flavodoxin) NADP+ reductase and flavodoxin; key components of electron transfer in <i>Escherichia coli</i>

scientific article published in 1999

Characterisation of flavodoxin NADP+ oxidoreductase and flavodoxin; key components of electron transfer in Escherichia coli

scientific article

Characterization of homologous sphingosine-1-phosphate lyase isoforms in the bacterial pathogen Burkholderia pseudomallei

scientific article

Characterization of secreted sphingosine-1-phosphate lyases required for virulence and intracellular survival of Burkholderia pseudomallei

scientific article

Cloning, expression, purification, crystallization and preliminary X-ray characterization of the full-length single-stranded DNA-binding protein from the hyperthermophilic bacterium Aquifex aeolicus.

scientific article

Conformational preferences of linear beta-defensins are revealed by ion mobility-mass spectrometry

scientific article

Continuous colorimetric assay that enables high-throughput screening of N-acetylamino acid racemases

scientific article published on 13 March 2015

Contributions of two UDP-glucose dehydrogenases to viability and polymyxin B resistance of Burkholderia cenocepacia

scientific article published on 21 April 2009

Covalent dimer species of beta-defensin Defr1 display potent antimicrobial activity against multidrug-resistant bacterial pathogens

scientific article published on 12 March 2007

Cubic crystals of chloramphenicol phosphotransferase fromStreptomyces venezuelaein complex with chloramphenicol

scientific article published on 01 May 1999

Defensin-related peptide 1 (Defr1) is allelic to Defb8 and chemoattracts immature DC and CD4+ T cells independently of CCR6.

scientific article

Desalting large protein complexes during native electrospray mass spectrometry by addition of amino acids to the working solution.

scientific article

Determination of Protein Thiol Reduction Potential by Isotope Labeling and Intact Mass Measurement

scientific article

Discovery of glutathione S-transferase inhibitors using dynamic combinatorial chemistry

scientific article

Dying and necrotic neutrophils are anti-inflammatory secondary to the release of alpha-defensins

scientific article

Effective Binding and Sensing of Lipopolysaccharide: Combining Complementary Pattern Recognition Receptors

scientific article published on 01 January 2009

Efficient production of human beta-defensin 2 (HBD2) in Escherichia coli

scientific article

Erratum: Use of isotopically labeled substrates reveals kinetic differences between human and bacterial serine palmitoyltransferase

scientific article published on 01 August 2019

Essential metals

scientific article published on 01 June 2007

Ferric ion (hydr)oxo clusters in the "Venus flytrap" cleft of FbpA: Mössbauer, calorimetric and mass spectrometric studies

scientific article published on 17 February 2012

Garlic revisited: antimicrobial activity of allicin-containing garlic extracts against Burkholderia cepacia complex

scientific article

Histidine ligands in bacterial metallothionein enhance cluster stability

scientific article published on 03 January 2007

Hydrogen Peroxide-Based Fluorometric Assay for Real-Time Monitoring of SAM-Dependent Methyltransferases

scholarly article by M Kalim Akhtar et al published 2018 in Frontiers in Bioengineering and Biotechnology

IL-1β-Induced Protection of Keratinocytes against Staphylococcus aureus-Secreted Proteases Is Mediated by Human β-Defensin 2.

scientific article published on 09 September 2016

Identification of the [Fe-S] Cluster-binding Residues ofEscherichia coliBiotin Synthase

scientific article published on 01 May 2000

Inhibition of the PLP-dependent enzyme serine palmitoyltransferase by cycloserine: evidence for a novel decarboxylative mechanism of inactivation

scientific article

Insight into Coenzyme A cofactor binding and the mechanism of acyl-transfer in an acylating aldehyde dehydrogenase from Clostridium phytofermentans

scientific article published on 22 February 2016

Insights into How Nucleotide-Binding Domains Power ABC Transport

scientific article

Insights into the conformations of three structurally diverse proteins: cytochrome c, p53, and MDM2, provided by variable-temperature ion mobility mass spectrometry

scientific article published on 25 February 2015

Interaction of human β-defensin 2 (HBD2) with glycosaminoglycans.

scientific article

Interrogating the molecular details of the peroxiredoxin activity of the Escherichia coli bacterioferritin comigratory protein using high-resolution mass spectrometry.

scientific article published in May 2009

Is it biologically relevant to measure the structures of small peptides in the gas-phase?

article

Isoleucine/leucine2 is essential for chemoattractant activity of beta-defensin Defb14 through chemokine receptor 6.

scientific article

Maturation of McjA precursor peptide into active microcin MccJ25.

scientific article published in August 2007

Mechanism of 8-amino-7-oxononanoate synthase: spectroscopic, kinetic, and crystallographic studies

scientific article

Mechanism of alpha-oxoamine synthases: identification of the intermediate Claisen product in the 8-amino-7-oxononanoate synthase reaction

scientific article

Metals in membranes

scientific article published on 10 April 2007

Molecular basis of Streptococcus mutans sortase A inhibition by the flavonoid natural product trans-chalcone

scientific article

N-Phenylputrescine (NPP): a natural product inspired amine donor for biocatalysis

scientific article published on 02 November 2021

Niobium uptake and release by bacterial ferric ion binding protein

scientific article published on 28 April 2010

Nitrilotriacetic acid-derivatized quantum dots for simple purification and site-selective fluorescent labeling of active proteins in a single step

scientific article

Nucleophilic catalysis of acylhydrazone equilibration for protein-directed dynamic covalent chemistry

scientific article

Oxo-iron clusters in a bacterial iron-trafficking protein: new roles for a conserved motif

scientific article

Peptide fragments of a beta-defensin derivative with potent bactericidal activity

scientific article

Plant host and sugar alcohol induced exopolysaccharide biosynthesis in the Burkholderia cepacia complex

scientific article published in August 2008

Preparation of isotopically labelled recombinant beta-defensin for NMR studies

scientific article

Probing the NADPH-binding site of Escherichia coli flavodoxin oxidoreductase

scientific article published on December 2000

Rational design of an inhibitor of dethiobiotin synthetase; interaction of 6-hydroxypyrimindin-4(3H)-one with the adenine base binding site

Reconstitution of the pyridoxal 5'-phosphate (PLP) dependent enzyme serine palmitoyltransferase (SPT) with pyridoxal reveals a crucial role for the phosphate during catalysis

scientific article published in August 2013

Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature

scientific article

Role of a conserved arginine residue during catalysis in serine palmitoyltransferase

scientific article

Short Oxo–Titanium(IV) Bond in Bacterial Transferrin: A Protein Target for Metalloantibiotics

scientific article published on 01 April 2006

Solution Structure and Conformational Dynamics of a Doublet Acyl Carrier Protein from Prodigiosin Biosynthesis

scientific article published on 08 January 2021

Sphingolipid biosynthesis in man and microbes

Structural and functional studies of the biotin protein ligase from Aquifex aeolicus reveal a critical role for a conserved residue in target specificity

scientific article

Structural evidence for the covalent modification of FabH by 4,5-dichloro-1,2-dithiol-3-one (HR45).

scientific article published on 17 July 2017

Structural, mechanistic and regulatory studies of serine palmitoyltransferase

scientific article published on June 2012

Structure-activity relationships in defensin dimers: a novel link between beta-defensin tertiary structure and antimicrobial activity

scientific article

Subdivision of the bacterioferritin comigratory protein family of bacterial peroxiredoxins based on catalytic activity

scientific article

Suicide inhibition of α-oxamine synthases: structures of the covalent adducts of 8-amino-7-oxononanoate synthase with trifluoroalanine

article

Synergistic anion and metal binding to the ferric ion-binding protein from Neisseria gonorrhoeae

scientific article published on 7 October 2002

Synthesis and application of a new cleavable linker for "click"-based affinity chromatography

scientific article published on 13 October 2009

Synthesis of N-acyl amide natural products using a versatile adenylating biocatalyst

scientific article published on 31 May 2019

Temperate bacteriophages DK4 and BcepMu fromBurkholderia cenocepaciaJ2315 are identical

scientific article published on 01 August 2005

The External Aldimine Form of Serine Palmitoyltransferase: STRUCTURAL, KINETIC, AND SPECTROSCOPIC ANALYSIS OF THE WILD-TYPE ENZYME AND HSAN1 MUTANT MIMICS

scientific article

The carbon chain-selective adenylation enzyme TamA: the missing link between fatty acid and pyrrole natural product biosynthesis.

scientific article published in April 2018

The chemical basis of serine palmitoyltransferase inhibition by myriocin

scientific article

The crystal structure of 8-amino-7-oxononanoate synthase: a bacterial PLP-dependent, acyl-CoA-condensing enzyme

scientific article

The mechanism of 7,8-diaminopelargonate synthase; the role of S-adenosylmethionine as the amino donor

scientific article published in October 2003

The pyridoxal 5'-phosphate (PLP)-dependent enzyme serine palmitoyltransferase (SPT): effects of the small subunits and insights from bacterial mimics of human hLCB2a HSAN1 mutations

scientific article published on 23 September 2013

The serine palmitoyltransferase from Sphingomonas wittichii RW1: An interesting link to an unusual acyl carrier protein

scientific article

The structure of serine palmitoyltransferase; gateway to sphingolipid biosynthesis

scientific article

Triazole biotin: a tight-binding biotinidase-resistant conjugate

scientific article published on 10 October 2013

Use of isotopically labeled substrates reveals kinetic differences between human and bacterial serine palmitoyltransferase

scientific article published on 21 February 2019

Using the pimeloyl-CoA synthetase adenylation fold to synthesize fatty acid thioesters

scientific article published on 17 April 2017

l-Penicillamine is a mechanism-based inhibitor of serine palmitoyltransferase by forming a pyridoxal-5′-phosphate-thiazolidine adduct

scholarly article by Jonathan Lowther et al published 2012 in MedChemComm

List of works by Dominic J Campopiano

A novel protein-mineral interface

A putative gene cluster for aminoarabinose biosynthesis is essential for Burkholderia cenocepacia viability

ACP-AasS you like it.

An improved racemase/acylase biotransformation for the preparation of enantiomerically pure amino acids

An investigation of flavoprotein redox partners

Analysis and separation of residues important for the chemoattractant and antimicrobial activities of beta-defensin 3.

Antimicrobial activity of CHIR-090, an inhibitor of lipopolysaccharide biosynthesis, against the Burkholderia cepacia complex

Assembly of an Oxo-Zirconium(IV) Cluster in a Protein Cleft

Binding a heparin derived disaccharide to defensin inspired peptides: insights to antimicrobial inhibition from gas-phase measurements

Biotinylation in the hyperthermophile Aquifex aeolicus

Bivalent enzyme inhibitors discovered using dynamic covalent chemistry

Characterisation of 8-amino-7-oxononanoate synthase: A bacterial PLP-dependent, acyl CoA condensing enzyme

Characterisation of DEFB107 by mass spectrometry: Lessons from an anti-antimicrobial defensin

Characterisation of ferredoxin (flavodoxin) NADP+ reductase and flavodoxin; key components of electron transfer in <i>Escherichia coli</i>

Characterisation of flavodoxin NADP+ oxidoreductase and flavodoxin; key components of electron transfer in Escherichia coli

Characterization of homologous sphingosine-1-phosphate lyase isoforms in the bacterial pathogen Burkholderia pseudomallei

Characterization of secreted sphingosine-1-phosphate lyases required for virulence and intracellular survival of Burkholderia pseudomallei

Cloning, expression, purification, crystallization and preliminary X-ray characterization of the full-length single-stranded DNA-binding protein from the hyperthermophilic bacterium Aquifex aeolicus.

Conformational preferences of linear beta-defensins are revealed by ion mobility-mass spectrometry

Continuous colorimetric assay that enables high-throughput screening of N-acetylamino acid racemases

Contributions of two UDP-glucose dehydrogenases to viability and polymyxin B resistance of Burkholderia cenocepacia

Covalent dimer species of beta-defensin Defr1 display potent antimicrobial activity against multidrug-resistant bacterial pathogens

Cubic crystals of chloramphenicol phosphotransferase fromStreptomyces venezuelaein complex with chloramphenicol

Defensin-related peptide 1 (Defr1) is allelic to Defb8 and chemoattracts immature DC and CD4+ T cells independently of CCR6.

Desalting large protein complexes during native electrospray mass spectrometry by addition of amino acids to the working solution.

Determination of Protein Thiol Reduction Potential by Isotope Labeling and Intact Mass Measurement

Discovery of glutathione S-transferase inhibitors using dynamic combinatorial chemistry

Dying and necrotic neutrophils are anti-inflammatory secondary to the release of alpha-defensins

Effective Binding and Sensing of Lipopolysaccharide: Combining Complementary Pattern Recognition Receptors

Efficient production of human beta-defensin 2 (HBD2) in Escherichia coli

Erratum: Use of isotopically labeled substrates reveals kinetic differences between human and bacterial serine palmitoyltransferase

Essential metals

Ferric ion (hydr)oxo clusters in the "Venus flytrap" cleft of FbpA: Mössbauer, calorimetric and mass spectrometric studies

Garlic revisited: antimicrobial activity of allicin-containing garlic extracts against Burkholderia cepacia complex

Histidine ligands in bacterial metallothionein enhance cluster stability

Hydrogen Peroxide-Based Fluorometric Assay for Real-Time Monitoring of SAM-Dependent Methyltransferases

IL-1β-Induced Protection of Keratinocytes against Staphylococcus aureus-Secreted Proteases Is Mediated by Human β-Defensin 2.

Identification of the [Fe-S] Cluster-binding Residues ofEscherichia coliBiotin Synthase

Inhibition of the PLP-dependent enzyme serine palmitoyltransferase by cycloserine: evidence for a novel decarboxylative mechanism of inactivation

Insight into Coenzyme A cofactor binding and the mechanism of acyl-transfer in an acylating aldehyde dehydrogenase from Clostridium phytofermentans

Insights into How Nucleotide-Binding Domains Power ABC Transport

Insights into the conformations of three structurally diverse proteins: cytochrome c, p53, and MDM2, provided by variable-temperature ion mobility mass spectrometry

Interaction of human β-defensin 2 (HBD2) with glycosaminoglycans.

Interrogating the molecular details of the peroxiredoxin activity of the Escherichia coli bacterioferritin comigratory protein using high-resolution mass spectrometry.

Is it biologically relevant to measure the structures of small peptides in the gas-phase?

Isoleucine/leucine2 is essential for chemoattractant activity of beta-defensin Defb14 through chemokine receptor 6.

Maturation of McjA precursor peptide into active microcin MccJ25.

Mechanism of 8-amino-7-oxononanoate synthase: spectroscopic, kinetic, and crystallographic studies

Mechanism of alpha-oxoamine synthases: identification of the intermediate Claisen product in the 8-amino-7-oxononanoate synthase reaction

Metals in membranes

Molecular basis of Streptococcus mutans sortase A inhibition by the flavonoid natural product trans-chalcone

N-Phenylputrescine (NPP): a natural product inspired amine donor for biocatalysis

Niobium uptake and release by bacterial ferric ion binding protein

Nitrilotriacetic acid-derivatized quantum dots for simple purification and site-selective fluorescent labeling of active proteins in a single step

Nucleophilic catalysis of acylhydrazone equilibration for protein-directed dynamic covalent chemistry

Oxo-iron clusters in a bacterial iron-trafficking protein: new roles for a conserved motif

Peptide fragments of a beta-defensin derivative with potent bactericidal activity

Plant host and sugar alcohol induced exopolysaccharide biosynthesis in the Burkholderia cepacia complex

Preparation of isotopically labelled recombinant beta-defensin for NMR studies

Probing the NADPH-binding site of Escherichia coli flavodoxin oxidoreductase

Rational design of an inhibitor of dethiobiotin synthetase; interaction of 6-hydroxypyrimindin-4(3H)-one with the adenine base binding site

Reconstitution of the pyridoxal 5'-phosphate (PLP) dependent enzyme serine palmitoyltransferase (SPT) with pyridoxal reveals a crucial role for the phosphate during catalysis

Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature

Role of a conserved arginine residue during catalysis in serine palmitoyltransferase

Short Oxo–Titanium(IV) Bond in Bacterial Transferrin: A Protein Target for Metalloantibiotics

Solution Structure and Conformational Dynamics of a Doublet Acyl Carrier Protein from Prodigiosin Biosynthesis

Sphingolipid biosynthesis in man and microbes

Structural and functional studies of the biotin protein ligase from Aquifex aeolicus reveal a critical role for a conserved residue in target specificity

Structural evidence for the covalent modification of FabH by 4,5-dichloro-1,2-dithiol-3-one (HR45).

Structural, mechanistic and regulatory studies of serine palmitoyltransferase

Structure-activity relationships in defensin dimers: a novel link between beta-defensin tertiary structure and antimicrobial activity

Subdivision of the bacterioferritin comigratory protein family of bacterial peroxiredoxins based on catalytic activity

Suicide inhibition of α-oxamine synthases: structures of the covalent adducts of 8-amino-7-oxononanoate synthase with trifluoroalanine

Synergistic anion and metal binding to the ferric ion-binding protein from Neisseria gonorrhoeae

Synthesis and application of a new cleavable linker for "click"-based affinity chromatography

Synthesis of N-acyl amide natural products using a versatile adenylating biocatalyst

Temperate bacteriophages DK4 and BcepMu fromBurkholderia cenocepaciaJ2315 are identical

The External Aldimine Form of Serine Palmitoyltransferase: STRUCTURAL, KINETIC, AND SPECTROSCOPIC ANALYSIS OF THE WILD-TYPE ENZYME AND HSAN1 MUTANT MIMICS

The carbon chain-selective adenylation enzyme TamA: the missing link between fatty acid and pyrrole natural product biosynthesis.