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List of works by Ian G Cowell

An overview of the visualisation and quantitation of low and high MW DNA adducts using the trapped in agarose DNA immunostaining (TARDIS) assay.

scientific article

Brief reports: Controlling the survival of human pluripotent stem cells by small molecule-based targeting of topoisomerase II alpha.

scientific article

Composite cis-acting epigenetic switches in eukaryotes: lessons from Drosophila Fab-7 for the Igf2-H19 imprinted domain.

scientific article

DNA-dependent protein kinase is a therapeutic target and an indicator of poor prognosis in B-cell chronic lymphocytic leukemia.

scientific article published in June 2008

Differential selection of acridine resistance mutations in human DNA topoisomerase IIbeta is dependent on the acridine structure

article

E4BP4/NFIL3, a PAR-related bZIP factor with many roles.

scientific article

Effect of TDP2 on the Level of TOP2-DNA Complexes and SUMOylated TOP2-DNA Complexes

scientific article published on 14 July 2018

Genome-wide ChIP-seq analysis of human TOP2B occupancy in MCF7 breast cancer epithelial cells

scientific article published on 12 October 2015

Glutathione transferase pi its minimal promoter and downstream cis-acting element.

scientific article published in April 1991

Histone deacetylase inhibition redistributes topoisomerase IIβ from heterochromatin to euchromatin

scientific article

Human Tra2 proteins jointly control a CHEK1 splicing switch among alternative and constitutive target exons

scientific article published on 11 September 2014

Intercalating TOP2 Poisons Attenuate Topoisomerase Action at Higher Concentrations

scientific article published on 09 August 2019

MRE11 facilitates the removal of human topoisomerase II complexes from genomic DNA.

scientific article

Mechanism of generation of therapy related leukemia in response to anti-topoisomerase II agents.

scientific article published on 31 May 2012

Molecular biology of glutathione transferases

scientific article published on 01 August 1987

Monoclonal antibodies against plant proteins recognise animal intermediate filaments

scientific article published on 01 January 1987

Myeloperoxidase Enhances Etoposide and Mitoxantrone-Mediated DNA Damage: A Target for Myeloprotection in Cancer Chemotherapy

scientific article (publication date: 2017)

NK314, a topoisomerase II inhibitor that specifically targets the alpha isoform.

scientific article

Nuclear distribution of human DNA topoisomerase IIbeta: a nuclear targeting signal resides in the 116-residue C-terminal tail.

scientific article published in September 1998

Proteasomal inhibition potentiates drugs targeting DNA topoisomerase II.

scientific article published on 12 January 2016

Self-association of chromo domain peptides.

scientific article published in February 1997

Small molecule inhibitors confirm ubiquitin-dependent removal of TOP2-DNA covalent complexes

scientific article published on 25 June 2020

TOP2B Is Required to Maintain the Adrenergic Neural Phenotype and for ATRA-Induced Differentiation of SH-SY5Y Neuroblastoma Cells

scientific article published in 2022

TOP2B: The First Thirty Years

scientific article published on 14 September 2018

The Deubiquitinating Enzyme Inhibitor PR-619 is a Potent DNA Topoisomerase II Poison

scientific article published on 12 September 2019

The gene and pseudogenes of Cbx3/mHP1 gamma.

scientific article

The human mitochondrial NADH: ubiquinone oxidoreductase 51-kDa subunit maps adjacent to the glutathione S-transferase P1-1 gene on chromosome 11q13.

scientific article

The role of topoisomerase II beta on breakage and proximity of RUNX1 to partner alleles RUNX1T1 and EVI1.

scientific article published on 5 November 2013

Topoisomerase II Chromatin Immunoprecipitation

scientific article published in January 2018

Transcriptional repression by a novel member of the bZIP family of transcription factors ⬇️

scientific article published on July 1, 1992

Visualization and Quantification of Topoisomerase-DNA Covalent Complexes Using the Trapped in Agarose Immunostaining (TARDIS) Assay

scientific article published in January 2018

gammaH2AX foci form preferentially in euchromatin after ionising-radiation.

scientific article

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