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List of works by Dong-Kug Choi

2-(5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazol-3-yl)-N-(2-hydroxyethyl)-2-oxoacetamide (CDMPO) has anti-inflammatory properties in microglial cells and prevents neuronal and behavioral deficits in MPTP mouse model of Parkinson's di

scientific article published on 27 December 2019

2-Hydroxy-4-Methylbenzoic Anhydride Inhibits Neuroinflammation in Cellular and Experimental Animal Models of Parkinson's Disease

scientific article published on 02 November 2020

A computational approach to the inference of sphingolipid pathways from the genome of Aspergillus fumigatus.

scientific article

A negative regulatory factor for the dark repression of Arabidopsis thaliana cab1 gene

scientific article published on 01 November 1996

A novel synthetic HTB derivative, BECT inhibits lipopolysaccharide-mediated inflammatory response by suppressing the p38 MAPK/JNK and NF-κB activation pathways.

scientific article

A novel synthetic compound MCAP suppresses LPS-induced murine microglial activation in vitro via inhibiting NF-kB and p38 MAPK pathways

scientific article published on February 2016

A novel synthetic compound PHID (8-Phenyl-6a, 7, 8, 9, 9a, 10-hexahydro-6H-isoindolo [5, 6-g] quinoxaline-7, 9-dione) protects SH-SY5Y cells against MPP+-induced cytotoxicity through inhibition of reactive oxygen species generation and JNK signaling ⬇️

scientific article published on October 12, 2010

Ablation of the inflammatory enzyme myeloperoxidase mitigates features of Parkinson's disease in mice.

scientific article published in July 2005

Acorus gramineus inhibits microglia mediated neuroinflammation and prevents neurotoxicity in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced mouse model of Parkinson's disease ⬇️

scientific article published on October 17, 2012

Advances in neuroprotective ingredients of medicinal herbs by using cellular and animal models of Parkinson's disease

scientific article

Ameliorative potential of desalted Salicornia europaea L. extract in multifaceted Alzheimer's-like scopolamine-induced amnesic mice model.

scientific article published on 8 May 2018

Analysis of Epidermal Growth Factor Receptor Related Gene Expression Changes in a Cellular and Animal Model of Parkinson's Disease.

scientific article published on 16 February 2017

Anti-Neuroinflammatory Agent, Restricticin B, from the Marine-Derived Fungus Penicillium janthinellum and Its Inhibitory Activity on the NO Production in BV-2 Microglia Cells ⬇️

scientific article published on 14 September 2020

Anti-inflammatory and anti-allergic effects of Agrimonia pilosa Ledeb extract on murine cell lines and OVA-induced airway inflammation.

scientific article published on 21 January 2012

Anti-neuroinflammatory activity of a novel cannabinoid derivative by inhibiting the NF-κB signaling pathway in lipopolysaccharide-induced BV-2 microglial cells.

scientific article published on February 2013

Anti-neuroinflammatory effects of DPTP, a novel synthetic clovamide derivative in in vitro and in vivo model of neuroinflammation.

scientific article

Antineuroinflammatory Activities and Neurotoxicological Assessment of Curcumin Loaded Solid Lipid Nanoparticles on LPS-Stimulated BV-2 Microglia Cell Models

scientific article published on 25 March 2019

Aqueous Extract of Dendropanax morbiferus Leaves Effectively Alleviated Neuroinflammation and Behavioral Impediments in MPTP-Induced Parkinson's Mouse Model.

scientific article

Atractylenolide-I Protects Human SH-SY5Y Cells from 1-Methyl-4-Phenylpyridinium-Induced Apoptotic Cell Death.

scientific article published on 8 May 2017

Attenuation of inflammatory-mediated neurotoxicity by Saururus chinensis extract in LPS-induced BV-2 microglia cells via regulation of NF-κB signaling and anti-oxidant properties

scientific article

Attenuation of neuroinflammatory responses and behavioral deficits by Ligusticum officinale (Makino) Kitag in stimulated microglia and MPTP-induced mouse model of Parkinson's disease

scientific article

Autocrine action and its underlying mechanism of nitric oxide on intracellular Ca2+ homeostasis in vascular endothelial cells.

scientific article published on September 2000

Cellular and molecular mediators of neuroinflammation in the pathogenesis of Parkinson's disease

scientific article

Cellular phenotypes as inflammatory mediators in Parkinson's disease: Interventional targets and role of natural products

scientific article published on 17 July 2018

Cognitive enhancing effects of alpha asarone in amnesic mice by influencing cholinergic and antioxidant defense mechanisms.

scientific article published on 7 August 2012

Cognitive-enhancing and ameliorative effects of acanthoside B in a scopolamine-induced amnesic mouse model through regulation of oxidative/inflammatory/cholinergic systems and activation of the TrkB/CREB/BDNF pathway

scientific article published on 08 May 2019

Comparative Studies on Behavioral, Cognitive and Biomolecular Profiling of ICR, C57BL/6 and Its Sub-Strains Suitable for Scopolamine-Induced Amnesic Models.

scientific article published on 9 August 2017

Corrigendum to "α-Asarone attenuates microglia-mediated neuroinflammation by inhibiting NF kappa B activation and mitigates MPTP-induced behavioral deficits in a mouse model of Parkinson's disease" [Neuropharm 97 (2015) 46-57].

scientific article

Cuminum cyminum extract attenuates scopolamine-induced memory loss and stress-induced urinary biochemical changes in rats: a noninvasive biochemical approach.

scientific article

Current application of phytocompound-based nanocosmeceuticals for beauty and skin therapy

scientific article

Cx43 Mediates Resistance against MPP⁺-Induced Apoptosis in SH-SY5Y Neuroblastoma Cells via Modulating the Mitochondrial Apoptosis Pathway.

scientific article published on November 2016

Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration

scholarly article

Dendropanax Morbiferus and Other Species from the Genus Dendropanax: Therapeutic Potential of Its Traditional Uses, Phytochemistry, and Pharmacology

scientific article published on 08 October 2020

Development of a selective and sensitive LC-MS/MS method for the quantification of α-asarone in mouse plasma and its application to pharmacokinetic studies.

scientific article published in February 2018

Dietary β-glucan regulates the levels of inflammatory factors, inflammatory cytokines, and immunoglobulins in interleukin-10 knockout mice

scientific article published on 24 March 2011

Differential effects of ethanol on glial signal transduction initiated by lipopolysaccharide and interferon-gamma.

scientific article published in October 2005

Differential regulation of HIF-3α in LPS-induced BV-2 microglial cells: Comparison and characterization with HIF-1α.

scientific article

Discovery of a novel compound: insight into mechanisms for acrylamide-induced axonopathy and colchicine-induced apoptotic neuronal cell death.

scientific article published on August 2001

Dual functionality of myeloperoxidase in rotenone-exposed brain-resident immune cells.

scientific article

EOP, a newly synthesized ethyl pyruvate derivative, attenuates the production of inflammatory mediators via p38, ERK and NF-κB pathways in lipopolysaccharide-activated BV-2 microglial cells.

scientific article

Effect of Taurine on Viability and Proliferation of Murine Melanoma B16F10 Cells

scientific article published on January 2015

Emerging preclinical pharmacological targets for Parkinson's disease

scientific article

Emerging signals modulating potential of ginseng and its active compounds focusing on neurodegenerative diseases

scientific article published on 31 January 2018

Fluorescent differential display analysis of gene expression in apoptotic neuroblastoma cells.

scientific article published in November 1998

G-Protein-Coupled Receptors in CNS: A Potential Therapeutic Target for Intervention in Neurodegenerative Disorders and Associated Cognitive Deficits

scientific article published on 23 February 2020

GPR4 Knockout Improves the Neurotoxin-Induced, Caspase-Dependent Mitochondrial Apoptosis of the Dopaminergic Neuronal Cell

scientific article published on 12 October 2020

Gastrodin protects apoptotic dopaminergic neurons in a toxin-induced Parkinson's disease model.

scientific article published on 3 March 2013

Glial cell response: A pathogenic factor in Parkinson's disease.

scientific article

Hypoxia Inducible Factor Pathway and Physiological Adaptation: A Cell Survival Pathway?

scientific article

Identification of two novel primate-specific genes in DSCR.

scientific article published in June 2002

Importance of GPCR-Mediated Microglial Activation in Alzheimer's Disease

scientific article published on 21 August 2018

Inhibitors of microglial neurotoxicity: focus on natural products

scientific article published on 25 January 2011

Isolation and expression of Napor/CUG-BP2 in embryo development.

scientific article published in June 2003

Major constituents and antimicrobial activity of Korean herb Acorus calamus.

scientific article published on 27 June 2011

Microfluidization trends in the development of nanodelivery systems and applications in chronic disease treatments

article published in 2018

Modulation of LPS-stimulated neuroinflammation in BV-2 microglia by Gastrodia elata: 4-Hydroxybenzyl alcohol is the bioactive candidate ⬇️

scientific article published on December 6, 2011

Molecular Insights into NR4A2(Nurr1): an Emerging Target for Neuroprotective Therapy Against Neuroinflammation and Neuronal Cell Death

scientific article published on 25 January 2019

Molecular cloning and characterization of a gene expressed in mouse developing tongue, mDscr5 gene, a homolog of human DSCR5 (Down syndrome Critical Region gene 5)

scientific journal article

Molecular effects of activated BV-2 microglia by mitochondrial toxin 1-methyl-4-phenylpyridinium.

scientific article published on 18 January 2012

MyD88-dependent toll-like receptor signaling is required for murine macrophages response to IS2 ⬇️

scientific article published on May 31, 2011

Natural Phyto-Bioactive Compounds for the Treatment of Type 2 Diabetes: Inflammation as a Target

scientific article

Natural product-derived pharmacological modulators of Nrf2/ARE pathway for chronic diseases.

scientific article published on January 2014

Neuropharmacological Potential and Delivery Prospects of Thymoquinone for Neurological Disorders.

scientific article

Neuroprotective Role of Atractylenolide-I in an In Vitro and In Vivo Model of Parkinson's Disease

scientific article

Neuroprotective effects of vanillyl alcohol in Gastrodia elata Blume through suppression of oxidative stress and anti-apoptotic activity in toxin-induced dopaminergic MN9D cells.

scientific article published on 24 June 2011

Neurotoxic Agent-Induced Injury in Neurodegenerative Disease Model: Focus on Involvement of Glutamate Receptors

scientific article published on 29 August 2018

New Polyenes from the Marine-Derived Fungus Talaromyces cyanescens with Anti-Neuroinflammatory and Cytotoxic Activities

scientific article published in 2021

Nuclear factor erythroid 2-related factor 2 signaling in Parkinson disease: a promising multi therapeutic target against oxidative stress, neuroinflammation and cell death.

scientific article published on December 2012

Osteonectin-expressing cells in human stomach cancer and their possible clinical significance

scientific article published on 01 October 2002

Pathogenic Upregulation of Glial Lipocalin-2 in the Parkinsonian Dopaminergic System.

scientific article published in May 2016

Pathogenic role of glial cells in Parkinson's disease.

scientific article

Phytobioactive compound-based nanodelivery systems for the treatment of type 2 diabetes mellitus - current status

scientific article published on 09 February 2017

Promising cannabinoid-based therapies for Parkinson's disease: motor symptoms to neuroprotection

scientific article

Protective effect of Chrysanthemum indicum Linne against 1-methyl-4-phenylpridinium ion and lipopolysaccharide-induced cytotoxicity in cellular model of Parkinson’s disease ⬇️

scientific article published on January 8, 2011

Purification and characterization of a nitric oxide inhibitory peptide from Ruditapes philippinarum.

scientific article published on 22 February 2012

Recent Advances on the Neuroprotective Potential of Antioxidants in Experimental Models of Parkinson’s Disease ⬇️

scientific article published on August 23, 2012

Recent Update on the Role of Chinese Material Medica and Formulations in Diabetic Retinopathy

scientific article published on 4 January 2017

Recent developments in solid lipid nanoparticle and surface-modified solid lipid nanoparticle delivery systems for oral delivery of phyto-bioactive compounds in various chronic diseases.

scientific article

Recent trends in the development of nanophytobioactive compounds and delivery systems for their possible role in reducing oxidative stress in Parkinson's disease models

scientific article

Recent updates in redox regulation and free radical scavenging effects by herbal products in experimental models of Parkinson's disease.

scientific article published on 26 September 2012

Regulation of Toll-Like Receptor (TLR) Signaling Pathway by Polyphenols in the Treatment of Age-Linked Neurodegenerative Diseases: Focus on TLR4 Signaling

scientific article published on 10 May 2019

Regulation of microglia activity by glaucocalyxin-A: attenuation of lipopolysaccharide-stimulated neuroinflammation through NF-κB and p38 MAPK signaling pathways

scientific article

Resveratrol Confers Protection against Rotenone-Induced Neurotoxicity by Modulating Myeloperoxidase Levels in Glial Cells ⬇️

scientific article published on April 8, 2013

Scoparone Inhibits LPS-Simulated Inflammatory Response by Suppressing IRF3 and ERK in BV-2 Microglial Cells.

scientific article published on 14 December 2016

Simultaneous Measurement of Serotonin, Dopamine and Their Metabolites in Mouse Brain Extracts by High-Performance Liquid Chromatography with Mass Spectrometry Following Derivatization with Ethyl Chloroformate ⬇️

scientific article published on November 29, 2012

Strategic selection of neuroinflammatory models in Parkinson's disease: evidence from experimental studies.

scientific article

Synthesis of Clovamide Analogues That Inhibit NO Production in Activated BV-2 Microglial Cells.

scientific article published on 8 June 2017

Taurine and its analogs in neurological disorders: Focus on therapeutic potential and molecular mechanisms

scientific article published on 21 May 2019

Thalidomide and lenalidomide extend survival in a transgenic mouse model of amyotrophic lateral sclerosis.

scientific article published in March 2006

The Ameliorative Effects of the Ethyl Acetate Extract of Salicornia europaea L. and Its Bioactive Candidate, Irilin B, on LPS-Induced Microglial Inflammation and MPTP-Intoxicated PD-Like Mouse Model ⬇️

scientific article published on 09 July 2019

The DNA sequence of human chromosome 21

scientific article (publication date: 18 May 2000)

The Methanol Extract of Allium cepa L. Protects Inflammatory Markers in LPS-Induced BV-2 Microglial Cells and Upregulates the Antiapoptotic Gene and Antioxidant Enzymes in N27-A Cells

scientific article published on 01 September 2019

The Role of Free Radicals in the Aging Brain and Parkinson’s Disease: Convergence and Parallelism ⬇️

scientific article published on August 21, 2012

Therapeutic strategies and nano-drug delivery applications in management of ageing Alzheimer's disease

scientific article published in November 2018

Toxin-Induced Experimental Models of Learning and Memory Impairment

scientific article

Traditional Korean East Asian medicines and herbal formulations for cognitive impairment.

scientific article

Two New Phomaligols from the Marine-Derived Fungus Aspergillus flocculosus and Their Anti-Neuroinflammatory Activity in BV-2 Microglial Cells ⬇️

scientific article published in 2021

Two molecular pathways initiate mitochondria-dependent dopaminergic neurodegeneration in experimental Parkinson's disease

scholarly article

α-Asarone attenuates microglia-mediated neuroinflammation by inhibiting NF kappa B activation and mitigates MPTP-induced behavioral deficits in a mouse model of Parkinson's disease.

scientific article published on 14 May 2015

β-Asarone (cis-2,4,5-trimethoxy-1-allyl phenyl), attenuates pro-inflammatory mediators by inhibiting NF-κB signaling and the JNK pathway in LPS activated BV-2 microglia cells.

scientific article

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