List of works - Jan Frayne

A re-evaluation of sperm protein 17 (Sp17) indicates a regulatory role in an A-kinase anchoring protein complex, rather than a unique role in sperm-zona pellucida binding

scientific article

Activation of KLF1 Enhances the Differentiation and Maturation of Red Blood Cells from Human Pluripotent Stem Cells.

scientific article

An immortalized adult human erythroid line facilitates sustainable and scalable generation of functional red cells

scientific article published on 14 March 2017

Analysis of the differential proteome of human erythroblasts during in vitro erythropoiesis by 2-D DIGE.

scientific article published on 26 August 2009

Blood group phenotypes resulting from mutations in erythroid transcription factors.

scientific article

Bone marrow sinusoidal endothelium controls terminal erythroid differentiation and reticulocyte maturation

scientific article published on 29 November 2021

Cloning and sequence analysis of rat fertilin alpha and beta--developmental expression, processing and immunolocalization

scientific journal article

Comparing the two leading erythroid lines BEL-A and HUDEP-2

scientific article published on 21 November 2019

Comparison of the Proteome of Adult and Cord Erythroid Cells, and Changes in the Proteome Following Reticulocyte Maturation.

scientific article published on 22 March 2016

Do fertilin beta and cyritestin play a major role in mammalian sperm--oolemma interactions? A critical re-evaluation of the use of peptide mimics in identifying specific oocyte recognition protiens.

scientific article

Effect of oxytocin on testosterone production by isolated rat Leydig cells is mediated via a specific oxytocin receptor.

scientific article published on June 1995

Effects of oxytocin on sperm transport in the pubertal rat

scientific article published on 01 July 1996

Enhancement of red blood cell transfusion compatibility using CRISPR-mediated erythroblast gene editing

scientific article published on 26 April 2018

Epididymal oxytocin in the rat: its origin and regulation

scientific article published on 01 October 1996

Epididymal specific, selenium-independent GPX5 protects cells from oxidative stress-induced lipid peroxidation and DNA mutation.

scientific article published on 21 May 2013

Expression of extracellular glutathione peroxidase type 5 (GPX5) in the rat male reproductive tract

scientific article

Expression of extracellular superoxide dismutase in the human male reproductive tract, detected using antisera raised against a recombinant protein

scientific article published on 01 March 1998

Expression of phosphatidylethanolamine-binding protein in the male reproductive tract: immunolocalisation and expression in prepubertal and adult rat testes and epididymides

scientific journal article

Generation of an immortalised erythroid cell line from haematopoietic stem cells of a haemoglobin E/β-thalassemia patient

scientific article published on 08 October 2020

Genetic manipulation of cell line derived reticulocytes enables dissection of host malaria invasion requirements

scientific article published on 23 August 2019

Human tMDC III: a sperm protein with a potential role in oocyte recognition.

scientific article

Induction of adult levels of β-globin in human erythroid cells that intrinsically express embryonic or fetal globin by transduction with KLF1 and BCL11A-XL

scientific article

Krüppeling erythropoiesis: an unexpected broad spectrum of human red blood cell disorders due to KLF1 variants

scientific article

Localisation of phosphatidylethanolamine-binding protein in the brain and other tissues of the rat

scientific journal article

Localization of oxytocin receptors in the human and macaque monkey male reproductive tracts: evidence for a physiological role of oxytocin in the male.

scientific article published on June 1998

MHC Class II positive cells and T cells in the equine endometrium throughout the oestrous cycle

scientific article published on 01 May 1994

MTAP-related increased erythroblast proliferation as a mechanism of polycythaemia vera

scientific article published on 18 November 2021

Macaque MDC family of proteins: sequence analysis, tissue distribution and processing in the male reproductive tract ⬇️

scientific article published on May 1, 1998

Mammalian sperm-egg recognition: does fertilin beta have a major role to play?

scientific article

Mutations in the second zinc finger of human EKLF reduce promoter affinity but give rise to benign and disease phenotypes.

scientific article published on 21 July 2011

Non-functional fertility genes in humans: contributory factors in reduced male fertility?

scientific article published on 01 January 1999

Optimization of an erythroid culture system to reduce the cost of production of red blood cells

scientific article published on 30 November 2018

Qualitative and quantitative comparison of the proteome of erythroid cells differentiated from human iPSCs and adult erythroid cells by multiplex TMT labelling and nanoLC-MS/MS

scientific article

Rat MDC family of proteins: Sequence analysis, tissue distribution, and expression in prepubertal and adult rat testis ⬇️

scientific article published on October 1, 1997

Reproducible immortalization of erythroblasts from multiple stem cell sources provides approach for sustainable RBC therapeutics

scientific article published on 12 June 2021

Secretory factors from OP9 stromal cells delay differentiation and increase the expansion potential of adult erythroid cells in vitro.

scientific article published on 31 January 2018

Sequence analysis of a variety of primate fertilin α genes: Evidence for non-functional genes in the gorilla and man ⬇️

scientific article published on September 1, 1998

Structure and kinetic characterization of human sperm-specific glyceraldehyde-3-phosphate dehydrogenase, GAPDS

scientific article

Structure of Insoluble Rat Sperm Glyceraldehyde-3-phosphate Dehydrogenase (GAPDH) via Heterotetramer Formation with Escherichia coli GAPDH Reveals Target for Contraceptive Design

scientific article

The MDC family of proteins and their processing during epididymal transit

scientific article

The effect of germ cell complement on the presence of oxytocin in the interstitial and seminiferous tubule fluid of the rat testis.

scientific article published in December 1994

The gene for the human tMDC I sperm surface protein is non-functional: implications for its proposed role in mammalian sperm-egg recognition.

scientific article published on August 1998

The majority of human glutathione peroxidase type 5 (GPX5) transcripts are incorrectly spliced: implications for the role of GPX5 in the male reproductive tract

scientific article

The potential use of sperm antigens as targets for immunocontraception; past, present and future.

scientific article

The spermatozoon at fertilisation: current understanding and future research directions.

scientific article

Vimentin expression is retained in erythroid cells differentiated from human iPSC and ESC and indicates dysregulation in these cells early in differentiation.

scientific article published on 29 April 2019

List of works by Jan Frayne

A re-evaluation of sperm protein 17 (Sp17) indicates a regulatory role in an A-kinase anchoring protein complex, rather than a unique role in sperm-zona pellucida binding

Activation of KLF1 Enhances the Differentiation and Maturation of Red Blood Cells from Human Pluripotent Stem Cells.

An immortalized adult human erythroid line facilitates sustainable and scalable generation of functional red cells

Analysis of the differential proteome of human erythroblasts during in vitro erythropoiesis by 2-D DIGE.

Blood group phenotypes resulting from mutations in erythroid transcription factors.

Bone marrow sinusoidal endothelium controls terminal erythroid differentiation and reticulocyte maturation

Cloning and sequence analysis of rat fertilin alpha and beta--developmental expression, processing and immunolocalization

Comparing the two leading erythroid lines BEL-A and HUDEP-2

Comparison of the Proteome of Adult and Cord Erythroid Cells, and Changes in the Proteome Following Reticulocyte Maturation.

Do fertilin beta and cyritestin play a major role in mammalian sperm--oolemma interactions? A critical re-evaluation of the use of peptide mimics in identifying specific oocyte recognition protiens.

Effect of oxytocin on testosterone production by isolated rat Leydig cells is mediated via a specific oxytocin receptor.

Effects of oxytocin on sperm transport in the pubertal rat

Enhancement of red blood cell transfusion compatibility using CRISPR-mediated erythroblast gene editing

Epididymal oxytocin in the rat: its origin and regulation

Epididymal specific, selenium-independent GPX5 protects cells from oxidative stress-induced lipid peroxidation and DNA mutation.

Expression of extracellular glutathione peroxidase type 5 (GPX5) in the rat male reproductive tract

Expression of extracellular superoxide dismutase in the human male reproductive tract, detected using antisera raised against a recombinant protein

Expression of phosphatidylethanolamine-binding protein in the male reproductive tract: immunolocalisation and expression in prepubertal and adult rat testes and epididymides

Generation of an immortalised erythroid cell line from haematopoietic stem cells of a haemoglobin E/β-thalassemia patient

Genetic manipulation of cell line derived reticulocytes enables dissection of host malaria invasion requirements

Human tMDC III: a sperm protein with a potential role in oocyte recognition.

Induction of adult levels of β-globin in human erythroid cells that intrinsically express embryonic or fetal globin by transduction with KLF1 and BCL11A-XL

Krüppeling erythropoiesis: an unexpected broad spectrum of human red blood cell disorders due to KLF1 variants

Localisation of phosphatidylethanolamine-binding protein in the brain and other tissues of the rat

Localization of oxytocin receptors in the human and macaque monkey male reproductive tracts: evidence for a physiological role of oxytocin in the male.

MHC Class II positive cells and T cells in the equine endometrium throughout the oestrous cycle

MTAP-related increased erythroblast proliferation as a mechanism of polycythaemia vera

Macaque MDC family of proteins: sequence analysis, tissue distribution and processing in the male reproductive tract ⬇️

Mammalian sperm-egg recognition: does fertilin beta have a major role to play?

Mutations in the second zinc finger of human EKLF reduce promoter affinity but give rise to benign and disease phenotypes.

Non-functional fertility genes in humans: contributory factors in reduced male fertility?

Optimization of an erythroid culture system to reduce the cost of production of red blood cells

Qualitative and quantitative comparison of the proteome of erythroid cells differentiated from human iPSCs and adult erythroid cells by multiplex TMT labelling and nanoLC-MS/MS

Rat MDC family of proteins: Sequence analysis, tissue distribution, and expression in prepubertal and adult rat testis ⬇️

Reproducible immortalization of erythroblasts from multiple stem cell sources provides approach for sustainable RBC therapeutics

Secretory factors from OP9 stromal cells delay differentiation and increase the expansion potential of adult erythroid cells in vitro.

Sequence analysis of a variety of primate fertilin α genes: Evidence for non-functional genes in the gorilla and man ⬇️

Structure and kinetic characterization of human sperm-specific glyceraldehyde-3-phosphate dehydrogenase, GAPDS

Structure of Insoluble Rat Sperm Glyceraldehyde-3-phosphate Dehydrogenase (GAPDH) via Heterotetramer Formation with Escherichia coli GAPDH Reveals Target for Contraceptive Design

The MDC family of proteins and their processing during epididymal transit

The effect of germ cell complement on the presence of oxytocin in the interstitial and seminiferous tubule fluid of the rat testis.

The gene for the human tMDC I sperm surface protein is non-functional: implications for its proposed role in mammalian sperm-egg recognition.

The majority of human glutathione peroxidase type 5 (GPX5) transcripts are incorrectly spliced: implications for the role of GPX5 in the male reproductive tract

The potential use of sperm antigens as targets for immunocontraception; past, present and future.

The spermatozoon at fertilisation: current understanding and future research directions.

Vimentin expression is retained in erythroid cells differentiated from human iPSC and ESC and indicates dysregulation in these cells early in differentiation.