List of works - Makoto Makishima

2-Methylene 19-nor-25-dehydro-1alpha-hydroxyvitamin D3 26,23-lactones: synthesis, biological activities and molecular basis of passive antagonism

scientific article

25 S-Adamantyl-23-yne-26,27-dinor-1α,25-dihydroxyvitamin D3: Synthesis, Tissue Selective Biological Activities, and X-ray Crystal Structural Analysis of Its Vitamin D Receptor Complex

scientific article published on 23 July 2018

Application of a Waveguide-Mode Sensor to Blood Testing for Hepatitis B Virus, Hepatitis C Virus, Human Immunodeficiency Virus and Infection

scientific article published on 11 April 2019

Co-Inhibition of the DNA Damage Response and CHK1 Enhances Apoptosis of Neuroblastoma Cells

scientific article published on 29 July 2019

Competitive Binding Assay with an Umbelliferone-Based Fluorescent Rexinoid for Retinoid X Receptor Ligand Screening

scientific article published on 18 September 2019

Convenient Retinoid X Receptor Binding Assay Based on Fluorescence Change of the Antagonist NEt-C343

scientific article published on 30 December 2020

Deletion of Prevents Diet-Induced Ectopic Fat Accumulation by Controlling Oxidative Capacity in the Skeletal Muscle

scientific article published on 18 September 2018

Discovery of a "Gatekeeper" Antagonist that Blocks Entry Pathway to Retinoid X Receptors (RXRs) without Allosteric Ligand Inhibition in Permissive RXR Heterodimers

scientific article published on 24 December 2020

Efficient Lead Finding, Activity Enhancement and Preliminary Selectivity Control of Nuclear Receptor Ligands Bearing a Phenanthridinone Skeleton

scientific article published on 18 July 2018

Frontline Science: Concanavalin A-induced acute hepatitis is attenuated in vitamin D receptor knockout mice with decreased immune cell function

scientific article published on 29 April 2019

Functional analyses of a novel missense and other mutations of the vitamin D receptor in association with alopecia.

scientific article published on 11 July 2017

Identification of a highly potent vitamin D receptor antagonist: (25S)-26-Adamantyl-25-hydroxy-2-methylene-22,23-didehydro-19,27-dinor-20-epi-vitamin D3 (ADMI3)

scientific article published on 12 December 2006

Increased SLAMF7high monocytes in myelofibrosis patients harboring JAK2V617F provide a therapeutic target of elotuzumab

scientific article published on 03 July 2019

Interaction between vitamin D receptor and vitamin D ligands: two-dimensional alanine scanning mutational analysis.

scientific article published in March 2003

Lithocholic Acid Is a Vitamin D Receptor Ligand That Acts Preferentially in the Ileum

scholarly article by Michiyasu Ishizawa published in July 2018

Liver X Receptors Regulate Cholesterol Metabolism and Immunity in Hepatic Nonparenchymal Cells

scientific article published on 11 October 2019

Liver X receptors regulate hepatic F4/80 + CD11b+ Kupffer cells/macrophages and innate immune responses in mice.

scientific article

Relationship between hemoglobin levels and vancomycin clearance in patients with sepsis

scientific article published on 14 March 2019

Structural determinants for vitamin D receptor response to endocrine and xenobiotic signals.

scientific article published on 2 October 2003

Synthesis and In Vitro Evaluation of Novel Liver X Receptor Agonists Based on Naphthoquinone Derivatives

scientific article published on 26 November 2019

Vitamin D receptor: ligand recognition and allosteric network

scientific article published in February 2006

Vitamin D3 derivatives with adamantane or lactone ring side chains are cell type-selective vitamin D receptor modulators

scientific article published on 26 February 2007

meta-Non-flat substituents: a novel molecular design to improve aqueous solubility in small molecule drug discovery

scientific article published on 17 December 2020

List of works by Makoto Makishima