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List of works by Maria Kavallaris

6α-Acetoxyanopterine: A Novel Structure Class of Mitotic Inhibitor Disrupting Microtubule Dynamics in Prostate Cancer Cells.

scientific article published on 19 October 2016

A 3D Bioprinter Specifically Designed for the High-Throughput Production of Matrix-Embedded Multicellular Spheroids

scientific article published on 28 September 2020

A Covalently Crosslinked Ink for Multimaterials Drop‐on‐Demand 3D Bioprinting of 3D Cell Cultures

scientific article

A Rationally Optimized Nanoparticle System for the Delivery of RNA Interference Therapeutics into Pancreatic Tumors in Vivo.

scientific article published on 15 June 2016

A covalently crosslinked bioink for multi-materials drop-on-demand 3D bioprinting of three-dimensional cell cultures

scientific article

A crisis in the making? Education, ageing populations and the future of the medical research workforce

scientific article published on February 2011

A high-throughput 3D bioprinted cancer cell migration and invasion model with versatile and broad biological applicability

scientific article published in 2022

A novel plant toxin, persin, with in vivo activity in the mammary gland, induces Bim-dependent apoptosis in human breast cancer cells

scientific article

A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction

scientific article published on 22 January 2019

A pedigree with autosomal dominant thrombocytopenia, red cell macrocytosis, and an occurrence of t(12:21) positive pre-B acute lymphoblastic leukemia.

scientific article

A photoelectrochemical platform for the capture and release of rare single cells.

scientific article published on 12 June 2018

A potent targeted cancer nanotherapeutic

scientific article published on 01 April 2019

A role for altered microtubule polymer levels in vincristine resistance of childhood acute lymphoblastic leukemia xenografts.

scientific article published on 6 November 2007

Acid-cleavable polymeric core-shell particles for delivery of hydrophobic drugs

scientific article published on 29 July 2006

Acid-labile core cross-linked micelles for pH-triggered release of antitumor drugs

scientific article published on 20 June 2008

Alterations in gamma-actin and tubulin-targeted drug resistance in childhood leukemia

scientific article published on October 2006

An Emerging Role for Tubulin Isotypes in Modulating Cancer Biology and Chemotherapy Resistance

scientific article published on 4 July 2017

Analyses of Tumor Burden In Vivo and Metastasis Ex Vivo Using Luciferase-Expressing Cancer Cells in an Orthotopic Mouse Model of Neuroblastoma

scientific article published on January 2016

Anti-fouling magnetic nanoparticles for siRNA delivery

article published in 2010

Application of Rapid Fluorescence Lifetime Imaging Microscopy (RapidFLIM) to Examine Dynamics of Nanoparticle Uptake in Live Cells

scientific article

Assessment of cholesterol-derived ionic copolymers as potential vectors for gene delivery

scientific article

Biologically Targeted Magnetic Hyperthermia: Potential and Limitations

scientific article published on 02 August 2018

Block co-polymer nanoparticles with degradable cross-linked core and low-molecular-weight PEG corona for anti-tumour drug delivery

scientific article published on 21 June 2010

Choice of Capping Group in Tripeptide Hydrogels Influences Viability in the Three-Dimensional Cell Culture of Tumor Spheroids

scientific article published on 07 December 2016

Class I beta-tubulin mutations in 2-methoxyestradiol-resistant acute lymphoblastic leukemia cells: implications for drug-target interactions

scientific article published on October 2008

Class III beta-tubulin mediates sensitivity to chemotherapeutic drugs in non small cell lung cancer

scientific article

Computational analysis of image-based drug profiling predicts synergistic drug combinations: applications in triple-negative breast cancer

scientific article

Concentration- and schedule-dependent effects of chemotherapy on the angiogenic potential and drug sensitivity of vascular endothelial cells

scientific article published on 10 November 2012

Correction to "effective delivery of siRNA into cancer cells and tumors using well-defined biodegradable cationic star polymers"

scientific article published on 18 February 2015

Cytoskeleton and paclitaxel sensitivity in breast cancer: the role of beta-tubulins

scientific article published on May 2007

Dextran-Catechin inhibits angiogenesis by disrupting copper homeostasis in endothelial cells

scientific article published on 09 August 2017

Dextran-Catechin: An anticancer chemically-modified natural compound targeting copper that attenuates neuroblastoma growth

scientific article published on 21 June 2016

Dextran-based doxorubicin nanocarriers with improved tumor penetration

scientific article published on 18 December 2013

Dicer-labile PEG conjugates for siRNA delivery

scientific article

Discovery of Thalicthuberine as a Novel Antimitotic Agent from Nature that Disrupts Microtubule Dynamics and Induces Apoptosis in Prostate Cancer Cells.

scientific article

Drug delivery: beyond active tumour targeting

scientific article published on 10 May 2014

Drug resistance mechanisms in cancer cells: a proteomics perspective.

scientific article

Dual Bioresponsive Mesoporous Silica Nanocarrier as an “AND” Logic Gate for Targeted Drug Delivery Cancer Cells

ENMD-1198, a new analogue of 2-methoxyestradiol, displays both antiangiogenic and vascular-disrupting properties

scientific article published on 4 May 2010

Effective Management of Advanced Angiosarcoma by the Synergistic Combination of Propranolol and Vinblastine-based Metronomic Chemotherapy: A Bench to Bedside Study

scientific article published on 17 February 2016

Effective delivery of siRNA into cancer cells and tumors using well-defined biodegradable cationic star polymers

scientific article published on 6 May 2013

Effects of MYCN antisense oligonucleotide administration on tumorigenesis in a murine model of neuroblastoma

scientific article published in September 2003

Effects of a novel long noncoding RNA, lncUSMycN, on N-Myc expression and neuroblastoma progression

scientific article published on 06 June 2014

Evolution of resistance to Aurora kinase B inhibitors in leukaemia cells

scientific article

Facile synthesis of lactoferrin conjugated ultra small large pore silica nanoparticles for the treatment of glioblastoma

scientific article

Functionalizing biodegradable dextran scaffolds using living radical polymerization: new versatile nanoparticles for the delivery of therapeutic molecules.

scientific article

Gamma-actin is involved in regulating centrosome function and mitotic progression in cancer cells

scientific article published on December 2015

Graphene oxide - gelatin nanohybrids as functional tools for enhanced Carboplatin activity in neuroblastoma cells

scientific article published on 24 December 2014

Growth inhibitory retinoid effects after recruitment of retinoid X receptor beta to the retinoic acid receptor beta promoter

scientific article

High temporal resolution RNA-seq time course data reveals mammalian lncRNA activation mirrors neighbouring protein-coding genes

scientific article

High temporal resolution RNA-seq time course data reveals widespread synchronous activation between mammalian lncRNAs and neighboring protein-coding genes

scientific article published in 2022

Identification of Novel Medulloblastoma Cell-Targeting Peptides for Use in Selective Chemotherapy Drug Delivery

scientific article published on 01 August 2019

Identification of glycan structure alterations on cell membrane proteins in desoxyepothilone B resistant leukemia cells

scientific article published on 22 August 2011

Identification of plasma complement C3 as a potential biomarker for neuroblastoma using a quantitative proteomic approach.

scientific article published on 4 November 2013

In vivo [64Cu]CuCl2 PET imaging reveals activity of Dextran-Catechin on tumor copper homeostasis

scientific article published on 09 November 2018

Integrative analysis of RUNX1 downstream pathways and target genes

scientific article

Interplay between MycN and c-Myc regulates radioresistance and cancer stem cell phenotype in neuroblastoma upon glutamine deprivation

scientific article published on 16 May 2020

Intra-tumoral copper modulates PD-L1 expression and influences tumor immune evasion

scientific article published on 18 August 2020

Intracellular nitric oxide delivery from stable NO-polymeric nanoparticle carriers.

scientific article

Involvement ofMDR1 P-glycoprotein in multifactorial resistance to methotrexate

scientific article published on 01 March 1996

Macromolecular Hydrogen Sulfide Donors Trigger Spatiotemporally Confined Changes in Cell Signaling.

scientific article published on 14 December 2015

Magnetic catechin-dextran conjugate as targeted therapeutic for pancreatic tumour cells

scientific article published on 16 January 2014

Manganese-Based Magnetic Layered Double Hydroxide Nanoparticle: A pH-Sensitive and Concurrently Enhanced <i>T</i><sub>1</sub>/<i>T</i><sub>2</sub>-Weighted Dual-Mode Magnetic Resonance Imaging Contrast Agent

scientific article published on 09 April 2019

Metronomic Chemotherapy Regimens Using Microtubule-Targeting Agents: Mechanisms of Action, Preclinical Activity and Future Developments

Metronomic chemotherapy: new rationale for new directions

scientific article published on 08 June 2010

Microtubule alterations and mutations induced by desoxyepothilone B: implications for drug-target interactions

scientific article published in July 2003

Microtubule alterations and resistance to tubulin-binding agents (review).

scientific article

Microtubule dynamics, mitotic arrest, and apoptosis: drug-induced differential effects of betaIII-tubulin

scientific article published on 4 May 2010

Microtubules and resistance to tubulin-binding agents

scientific article published on 11 February 2010

Microtubules and their role in cellular stress in cancer

scientific article

Microtubules: a dynamic target in cancer therapy.

scientific article published on March 2008

Minimum information reporting in bio-nano experimental literature

scientific article published on 06 September 2018

Modeling the Distribution of Diprotic Basic Drugs in Liposomal Systems: Perspectives on Malaria Nanotherapy

scientific article published on 25 September 2019

Modulating the Selectivity and Stealth Properties of Ellipsoidal Polymersomes through a Multivalent Peptide Ligand Display

scientific article published on 19 May 2020

N-alkylisatin-based microtubule destabilizers bind to the colchicine site on tubulin and retain efficacy in drug resistant acute lymphoblastic leukemia cell lines with less in vitro neurotoxicity

scientific article published on 15 May 2020

Nanoparticles for radiooncology: Mission, vision, challenges.

scientific article published on 14 December 2016

Neuronal-associated microtubule proteins class III beta-tubulin and MAP2c in neuroblastoma: role in resistance to microtubule-targeted drugs

scientific article published on 01 September 2004

Novel functional cisplatin carrier based on carbon nanotubes–quercetin nanohybrid induces synergistic anticancer activity against neuroblastoma in vitro

Nucleic acid hybridization on an electrically reconfigurable network of gold-coated magnetic nanoparticles enables microRNA detection in blood

scientific article published on 27 August 2018

Partial depletion of gamma-actin suppresses microtubule dynamics

scientific article published on 17 January 2013

Perceptions in health and medical research careers: the Australian Society for Medical Research Workforce Survey

article

Potential applications of nanotechnology for the diagnosis and treatment of pancreatic cancer

scientific article published on 24 January 2014

Potential mechanisms of resistance to microtubule inhibitors

scientific article published on June 2008

Precise, high-throughput production of multicellular spheroids with a bespoke 3D bioprinter

scientific article

Preclinical small molecule WEHI-7326 overcomes drug resistance and elicits response in patient-derived xenograft models of human treatment-refractory tumors

scientific article published on 12 March 2021

Propranolol potentiates the anti-angiogenic effects and anti-tumor efficacy of chemotherapy agents: implication in breast cancer treatment

scientific article published on October 2011

Proteome analysis of vinca alkaloid response and resistance in acute lymphoblastic leukemia reveals novel cytoskeletal alterations.

scientific article

Proteomic analysis reveals a novel role for the actin cytoskeleton in vincristine resistant childhood leukemia--an in vivo study.

scientific article published in March 2006

Proteomics and disease: opportunities and challenges.

scientific article

Role of pancreatic stellate cells in chemoresistance in pancreatic cancer.

scientific article published on 09 April 2014

Spatial-temporal analysis of nanoparticles in live tumor spheroids impacted by cell origin and density

scientific article

Specific β-tubulin isotypes can functionally enhance or diminish epothilone B sensitivity in non-small cell lung cancer cells

scientific article

Stathmin levels alter PTPN14 expression and impact neuroblastoma cell migration

scientific article published on 06 December 2019

Stimuli-responsive functionalized mesoporous silica nanoparticles for drug release in response to various biological stimuli

scientific article published on 23 September 2013

Synthesis, anti-cancer and anti-inflammatory activity of novel 2-substituted isoflavenes.

scientific article published on 17 August 2014

TRIM16 acts as an E3 ubiquitin ligase and can heterodimerize with other TRIM family members

scientific article

TRIM16 inhibits neuroblastoma cell proliferation through cell cycle regulation and dynamic nuclear localization

scientific article published on 19 February 2013

TUBB3/βIII-tubulin acts through the PTEN/AKT signaling axis to promote tumorigenesis and anoikis resistance in non-small cell lung cancer

scientific article

Targeted Doxorubicin-Loaded Bacterially Derived Nano-Cells for the Treatment of Neuroblastoma.

scientific article

Targeting Functional Activity of AKT Has Efficacy against Aggressive Neuroblastoma

scientific article published on 23 January 2020

Targeting RSPO3-LGR4 Signaling for Leukemia Stem Cell Eradication in Acute Myeloid Leukemia

scientific article published on 01 June 2020

Targeting βIII-tubulin in glioblastoma multiforme: from cell biology and histopathology to cancer therapeutics

scientific article

The BET bromodomain inhibitor exerts the most potent synergistic anticancer effects with quinone-containing compounds and anti-microtubule drugs

scientific article

The RhoGAP protein ARHGAP18/SENEX localizes to microtubules and regulates their stability in endothelial cells

scientific article

The Use of Star Polymer Nanoparticles for the Delivery of siRNA to Mouse Orthotopic Pancreatic Tumor Models

scientific article published on 01 January 2019

The cyclin-dependent kinase inhibitor, p21(WAF1), promotes angiogenesis by repressing gene transcription of thioredoxin-binding protein 2 in cancer cells

scientific article published on 22 September 2009

The cytoskeleton as a therapeutic target in childhood acute leukemia: obstacles and opportunities

scientific article published on June 2007

The endocytic pathway and therapeutic efficiency of doxorubicin conjugated cholesterol-derived polymers

scientific article published on 25 September 2014

The estrogen-responsive B box protein (EBBP) restores retinoid sensitivity in retinoid-resistant cancer cells via effects on histone acetylation

scientific article

The estrogen-responsive B box protein is a novel regulator of the retinoid signal

scientific article

The retinoid signalling molecule, TRIM16, is repressed during squamous cell carcinoma skin carcinogenesis in vivo and reduces skin cancer cell migration in vitro

scientific article

Therapeutic targeting of polo-like kinase 1 using RNA-interfering nanoparticles (iNOPs) for the treatment of non-small cell lung cancer

scientific article published in May 2015

Thiol-Reactive Star Polymers Functionalized with Short Ethoxy-Containing Moieties Exhibit Enhanced Uptake in Acute Lymphoblastic Leukemia Cells

scientific article published on 11 December 2019

Thymosin-β4 is a determinant of drug sensitivity for Fenretinide and Vorinostat combination therapy in neuroblastoma.

scientific article published on 29 April 2015

Tissue-specific tropomyosin isoform composition

scientific article

Tubulin-targeted drug action: functional significance of class ii and class IVb beta-tubulin in vinca alkaloid sensitivity

scientific article

Tuneable catechin functionalisation of carbohydrate polymers

scientific article published on 23 April 2017

Using fluorescence lifetime imaging microscopy to monitor theranostic nanoparticle uptake and intracellular doxorubicin release

scientific article

Water Soluble Antioxidant Dextran-Quercetin Conjugate with Potential Anticancer Properties.

scientific article published on 7 February 2018

When polymers meet carbon nanostructures: expanding horizons in cancer therapy

scientific article published on 01 August 2019

betaIII-tubulin is a multifunctional protein involved in drug sensitivity and tumorigenesis in non-small cell lung cancer

scientific article

miR-99b-5p, miR-380-3p, and miR-485-3p are novel chemosensitizing miRNAs in high-risk neuroblastoma

scientific article

β-tubulin carboxy-terminal tails exhibit isotype-specific effects on microtubule dynamics in human gene-edited cells

article

βIII-Tubulin Structural Domains Regulate Mitochondrial Network Architecture in an Isotype-Specific Manner

scientific article

βIII-Tubulin alters glucose metabolism and stress response signaling to promote cell survival and proliferation in glucose-starved non-small cell lung cancer cells

scientific article published on 4 May 2016

βIII-tubulin: a novel mediator of chemoresistance and metastases in pancreatic cancer

scientific article

γ-Actin plays a key role in endothelial cell motility and neovessel maintenance

scientific article

γ-Actin regulates cell migration and modulates the ROCK signaling pathway

scientific article published on 9 September 2011

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