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List of works by Toos Daemen

A rationally designed combined treatment with an alphavirus-based cancer vaccine, sunitinib and low-dose tumor irradiation completely blocks tumor development

scientific article

A systematic analysis on the clinical safety and efficacy of onco-virotherapy

scientific article published on 05 October 2021

A virosomal immunization strategy against cervical cancer and pre-malignant cervical disease.

scientific article published on January 2006

Alphavirus-based vaccines encoding nonstructural proteins of hepatitis C virus induce robust and protective T-cell responses

scientific article published on 27 December 2013

An alphavirus-based therapeutic cancer vaccine: from design to clinical trial

scientific article published on 21 November 2018

Antigen-specific active immunotherapy for ovarian cancer

scientific article (publication date: 17 September 2014)

Antigen-specific active immunotherapy for ovarian cancer

scientific article

Antigen-specific active immunotherapy for ovarian cancer

Antigen-specific immunotherapy in ovarian cancer and p53 as tumor antigen

scientific article published on January 2012

Antitumor reactivity induced by liposomal MTP-PE in a liver metastasis model of colon cancer in the rat ⬇️

scientific article published on September 1, 1995

Augmentation of alphavirus vector-induced human papilloma virus-specific immune and anti-tumour responses by co-expression of interleukin-12.

scientific article published on 27 November 2008

CD103+ tumor-infiltrating lymphocytes are tumor-reactive intraepithelial CD8+ T cells associated with prognostic benefit and therapy response in cervical cancer.

scientific article

Changes in (risk) behavior and HPV knowledge among Dutch girls eligible for HPV vaccination: an observational cohort study.

scientific article published on 5 July 2018

Delivery of protein antigens to the immune system by fusion-active virosomes: a comparison with liposomes and ISCOMs

scientific article

Down-regulation of proteasomal subunit MB1 is an independent predictor of improved survival in ovarian cancer.

scientific article published on 24 February 2009

Enhancement of human papilloma virus type 16 E7 specific T cell responses by local invasive procedures in patients with (pre)malignant cervical neoplasia

scientific article

Epitope Prediction Assays Combined with Validation Assays Strongly Narrows down Putative Cytotoxic T Lymphocyte Epitopes

scientific article published on 24 March 2015

Equity in human papilloma virus vaccination uptake?: sexual behaviour, knowledge and demographics in a cross-sectional study in (un)vaccinated girls in the Netherlands

scientific article

Eradication of established HPV16-transformed tumours after immunisation with recombinant Semliki Forest virus expressing a fusion protein of E6 and E7.

scientific article published on March 2003

From tumor immunosuppression to eradication: targeting homing and activity of immune effector cells to tumors

scientific article

HLA class I alleles and cervical neoplasia

scientific article published on 01 May 2003

HPV-specific immunotherapy: key role for immunomodulators

scientific article published on February 2014

Hepatitis C virus core or NS3/4A protein expression preconditions hepatocytes against oxidative stress and endoplasmic reticulum stress

scientific article published on 01 December 2019

Heterologous prime-boost immunizations with a virosomal and an alphavirus replicon vaccine

scientific article published on 23 September 2010

Histochemical and electron microscopic characterization of hepatic macrophage subfractions isolated from normal and liposomal muramyl dipeptide treated rats ⬇️

scientific article published on 01 June 1995

Immunization with a P53 synthetic long peptide vaccine induces P53-specific immune responses in ovarian cancer patients, a phase II trial

scientific article published in November 2009

Immunological and Clinical Effects of Vaccines Targeting p53‐Overexpressing Malignancies ⬇️

scientific article published on March 15, 2011

Inclusion of the benefits of enhanced cross-protection against cervical cancer and prevention of genital warts in the cost-effectiveness analysis of human papillomavirus vaccination in the Netherlands

scientific article

Induction of cytotoxic T lymphocyte activity by immunization with recombinant Semliki Forest virus: indications for cross-priming

scientific article published on March 2004

Influenza virosomes in vaccine development

scientific article published on 01 January 2003

Influenza virosomes: combining optimal presentation of hemagglutinin with immunopotentiating activity

scientific article

Long-term clinical and immunological effects of p53-SLP® vaccine in patients with ovarian cancer

scientific article published on 09 May 2011

Multimodality treatment warranted for ovarian cancer: immunotherapy, a prerequisite to improve prognosis for this vicious disease

scientific article published on 01 March 2009

Myeloid derived suppressor cells-An overview of combat strategies to increase immunotherapy efficacy

scientific article

On discounting of health gains from human papillomavirus vaccination: effects of different approaches.

scientific article published on 29 March 2012

P53-specific T cell responses in patients with malignant and benign ovarian tumors: implications for p53 based immunotherapy

scientific article published in August 2007

Potent therapeutic efficacy of an alphavirus replicon DNA vaccine expressing human papilloma virus E6 and E7 antigens

scientific article published on 26 July 2018

Potential target antigens for a universal vaccine in epithelial ovarian cancer

scientific article

Potentiation of a p53-SLP vaccine by cyclophosphamide in ovarian cancer: a single-arm phase II study

scientific article published on 31 January 2012

Prognostic significance of tumor-infiltrating T-lymphocytes in primary and metastatic lesions of advanced stage ovarian cancer

scientific article published on 13 September 2008

Recombinant alphaviruses as vectors for anti-tumour and anti-microbial immunotherapy

scientific article

Role of T cell competition in the induction of cytotoxic T lymphocyte activity during viral vector-based immunization regimens

scientific article

Role of regulatory T-cells in immunization strategies involving a recombinant alphavirus vector system

scientific article published on 01 January 2011

Serum cytokine profiling as a diagnostic and prognostic tool in ovarian cancer: a potential role for interleukin 7

scientific article published on 01 April 2007

Sunitinib depletes myeloid-derived suppressor cells and synergizes with a cancer vaccine to enhance antigen-specific immune responses and tumor eradication

scientific article published on 7 January 2015

Superior therapeutic efficacy of alphavirus-mediated immunization against human papilloma virus type 16 antigens in a murine tumour model: effects of the route of immunization.

scientific article

Survival of ovarian cancer patients overexpressing the tumour antigen p53 is diminished in case of MHC class I down-regulation

scientific article published on 20 June 2008

Tattoo Delivery of a Semliki Forest Virus-Based Vaccine Encoding Human Papillomavirus E6 and E7.

scientific article published on 24 March 2015

The effect of pre-existing immunity on the capacity of influenza virosomes to induce cytotoxic T lymphocyte activity

scientific article published on 19 March 2008

The prognostic influence of tumour-infiltrating lymphocytes in cancer: a systematic review with meta-analysis ⬇️

scientific article published on May 31, 2011

The virosome concept for influenza vaccines

scientific article

Therapeutic immunization and local low-dose tumor irradiation, a reinforcing combination

scientific article published on 4 September 2013

Therapeutic vaccination against chronic hepatitis C virus infection

scientific article published on 25 July 2012

Treatment Regimen, Surgical Outcome, and T-cell Differentiation Influence Prognostic Benefit of Tumor-Infiltrating Lymphocytes in High-Grade Serous Ovarian Cancer.

scientific article published on 18 September 2015

Tumor-infiltrating cytotoxic T lymphocytes as independent prognostic factor in epithelial ovarian cancer with wilms tumor protein 1 overexpression

scientific article

Until which age should women be vaccinated against HPV infection? Recommendation based on cost-effectiveness analyses

scientific article published on 01 August 2011

Vaccination against Oncoproteins of HPV16 for Noninvasive Vulvar/Vaginal Lesions: Lesion Clearance Is Related to the Strength of the T-Cell Response.

scientific article published on 26 January 2016

Vaccine-based clinical trials in ovarian cancer

scientific article published on June 2011

Virosome-mediated delivery of protein antigens in vivo: efficient induction of class I MHC-restricted cytotoxic T lymphocyte activity.

scientific article

Virosome-mediated delivery of protein antigens to dendritic cells

scientific article published on 01 May 2002

Virosomes for antigen and DNA delivery

scientific article

Virosomes in vaccine development: induction of cytotoxic T lymphocyte activity with virosome-encapsulated protein antigens

scientific article

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