Search filters

List of works by Bruce Whitelaw

A Csf1r-EGFP Transgene Provides a Novel Marker for Monocyte Subsets in Sheep

scientific article published on 12 August 2016

A future for transgenic livestock.

scientific article published on October 2003

A high resolution atlas of gene expression in the domestic sheep (Ovis aries).

scientific article published on 15 September 2017

A preliminary proteomic characterisation of extracellular vesicles released by the ovine parasitic nematode, Teladorsagia circumcincta

scientific article published on 17 March 2016

A virus-neutralising antibody is not cytotoxic in vitro.

scientific article

Animal and cellular models of human disease

scientific article published on 20 October 2015

Behaviour of postnatally growth-impaired mice during malnutrition and after partial weight recovery.

scientific article published on 4 December 2012

Bovine telomere dynamics and the association between telomere length and productive lifespan

scientific article published in Scientific Reports

C9ORF72 repeat expansion causes vulnerability of motor neurons to Ca2+-permeable AMPA receptor-mediated excitotoxicity

scientific article

CD13/aminopeptidase N is a negative regulator of mast cell activation

scientific article

CRISPR-Based Gene Drives for Pest Control

scientific article published on 9 November 2017

Characterisation and cardiac directed differentiation of canine adult cardiac stem cells.

scientific article

Characterisation and differentiation potential of bone marrow derived canine mesenchymal stem cells

scientific article published on 20 June 2012

Chromatin heterogeneity within multicopy transgene arrays

scientific article published on 01 September 1998

Chromosomal position effects and the modulation of transgene expression.

scientific article

Comparable processing of beta-lactoglobulin pre-mRNA in cell culture and transgenic mouse models

scientific article published on 01 September 1996

Comparison of CRISPR/Cas9 and TALENs on editing an integrated EGFP gene in the genome of HEK293FT cells

scientific article published on 21 June 2016

Comparison of surrogate reporter systems for enrichment of cells with mutations induced by genome editors

scientific article published on 14 January 2016

Derivation and Characterization of Induced Pluripotent Stem Cells from Equine Fibroblasts ⬇️

scientific article published on September 28, 2012

Distal transgene insertion affects CpG island maintenance during differentiation.

scientific article

Dolly for dinner? Assessing commercial and regulatory trends in cloned livestock

scientific article published on 01 January 2007

Ectopic expression of beta-lactoglobulin transgenes.

scientific article published in March 1995

Efficient TALEN-mediated gene knockout in livestock

scientific article

Efficient generation of transgenic pigs using equine infectious anaemia virus (EIAV) derived vector.

scientific article published in July 2004

Engineering large animal models of human disease

scientific article

Erratum for Burkard et al., "Pigs Lacking the Scavenger Receptor Cysteine-Rich Domain 5 of CD163 Are Resistant to Porcine Reproductive and Respiratory Syndrome Virus 1 Infection"

scientific article published on 16 July 2020

Erratum to: Potential of promotion of alleles by genome editing to improve quantitative traits in livestock breeding programs

scientific article published on 11 September 2015

Expression of c-mycIs Down-regulated as Mouse Mammary Epithelial Cells Become Confluent

scientific article published on 01 October 1997

Feline mammary carcinoma stem cells are tumorigenic, radioresistant, chemoresistant and defective in activation of the ATM/p53 DNA damage pathway ⬇️

scientific article published on 07 December 2012

Gene Drive: Past, Present and Future Roads to Vertebrate Biocontrol

Gene targeting, genome editing: from Dolly to editors

scientific article

Generation of functional neurons from feeder-free, keratinocyte-derived equine induced pluripotent stem cells.

scientific article

Generation of germline ablated male pigs by CRISPR/Cas9 editing of the NANOS2 gene.

scientific article published on 10 January 2017

Genetically engineering milk

scientific article published on February 2016

Genome Editing and the Future of Farming meeting report

scientific article published on 31 January 2017

Genome edited sheep and cattle.

scientific article published on 10 September 2014

Global gene expression analysis of canine osteosarcoma stem cells reveals a novel role for COX-2 in tumour initiation.

scientific article published on 08 January 2014

Highly efficient targeted chromosome deletions using CRISPR/Cas9.

scientific article

Hormonal Influences on β-Lactoglobulin Transgene Expression Inferred from Chromatin Structure

scientific article published on 01 July 1996

Illuminating Role of CYP1A1 in Skin Function

scientific article published on 10 January 2008

Insulin-like growth factor binding proteins initiate cell death and extracellular matrix remodeling in the mammary gland.

scientific article

Introduction to Mammalian Genome Special Issue: Genome Editing

scientific article published on 01 August 2017

Intronic sequences modulate the sensitivity of β-lactoglobulin transgenes to position effects

scientific article published on 01 July 1997

Large animal models of cardiovascular disease

scientific article

Lentiviral transgenesis in livestock

scientific article published on 07 October 2010

Lentiviral vectors containing mouse Csf1r control elements direct macrophage-restricted expression in multiple species of birds and mammals

scientific article published on 9 April 2014

Live Lambs Born from Zona-Pellucida Denuded Embryos

scientific article published on 01 January 2005

Livestock 2.0 - genome editing for fitter, healthier, and more productive farmed animals

scientific article published on 26 November 2018

Longitudinal changes in telomere length and associated genetic parameters in dairy cattle analysed using random regression models

scientific article published on 13 February 2018

Mammalian interspecies substitution of immune modulatory alleles by genome editing

scientific article published on 22 February 2016

Mammary gland differentiation inversely correlates with GDF-8 expression.

scientific article published in December 2008

Marker genes for activation of the RNA interference (RNAi) pathway in the free-living nematode Caenorhabditis elegans and RNAi development in the ovine nematode Teladorsagia circumcincta

scientific article published on 18 December 2013

Matrix attachment region regulates basal beta-lactoglobulin transgene expression.

scientific article

Method Specific Calibration Corrects for DNA Extraction Method Effects on Relative Telomere Length Measurements by Quantitative PCR

scientific article

Milk lacking α-casein leads to permanent reduction in body size in mice

scientific article

Mono-allelic expression of variegating transgene locus in the mouse.

scientific article published on December 2003

Multiple copies of beta-lactoglobulin promoter do not function as LCR.

scientific article published on May 2000

New insights and current tools for genetically engineered (GE) sheep and goats

scientific article published on 21 April 2016

Novel GM animal technologies and their governance.

scientific article published on 19 June 2013

On the Use of Post-Transcriptional Processing Elements in Transgenes

scientific article published on 01 February 2004

Ovine-Induced Pluripotent Stem Cells Can Contribute to Chimeric Lambs ⬇️

scientific article published on January 4, 2012

Peroxiredoxin Gene Expression Signatures in Liver Reflect Toxic Insult

article

Pigs Lacking the Scavenger Receptor Cysteine-Rich Domain 5 of CD163 Are Resistant to Porcine Reproductive and Respiratory Syndrome Virus 1 Infection

scientific article published on 31 July 2018

Position-independent expression of the ovine beta-lactoglobulin gene in transgenic mice ⬇️

scientific article published on August 15, 1992

Potential of gene drives with genome editing to increase genetic gain in livestock breeding programs

scientific article published on 4 January 2017

Potential of promotion of alleles by genome editing to improve quantitative traits in livestock breeding programs.

scientific article published on 2 July 2015

Precision engineering for PRRSV resistance in pigs: Macrophages from genome edited pigs lacking CD163 SRCR5 domain are fully resistant to both PRRSV genotypes while maintaining biological function

scientific article

Precision genetics for complex objectives in animal agriculture

scientific article

Production of transgenic farm animals by viral vector-mediated gene transfer.

scientific article published on July 2008

Promoter characterization and functional association with placenta of porcine MAGEL2.

scientific article published on 12 June 2014

Rapid cohort generation and analysis of disease spectrum of large animal model of cone dystrophy

scientific article

Recommendations for minimum information for publication of experimental pathology data: MINPEPA guidelines

scientific article

Regulation of Ovine β-Lactoglobulin Gene Expression During the First Stage of Lactogenesis

article

Relative transgene expression frequencies in homozygous versus hemizygous transgenic mice.

scientific article published on 20 July 2013

Reprogramming Pig Fetal Fibroblasts Reveals a Functional LIF Signaling Pathway

scientific article published on 17 February 2012

Spatial monitoring of toxicity in HMOX-LacZ transgenic mice.

scientific article published on 14 January 2010

Spatial p21 expression profile in the mid-term mouse embryo.

scientific article published on 28 March 2010

Species-specific variation in RELA underlies differences in NF-κB activity: a potential role in African swine fever pathogenesis.

scientific article

Stat5 as a Target for Regulation by Extracellular Matrix

scientific article published on 01 September 1995

Strategies for production of pharmaceutical proteins in milk.

scientific article

TT2013 meeting report: the Transgenic Technology meeting visits Asia for the first time.

scientific article published on 19 April 2013

TT2016 meeting report on the 13th Transgenic Technology meeting in Prague, Czech Republic.

scientific article published on 8 June 2016

Temporal profiles of appearance of DNase I hypersensitive sites associated with the ovine b-lactoglobulin gene differ in sheep and transgenic mice ⬇️

scientific article published on April 1, 1998

The Genome Editing Revolution in Livestock Marches on

scientific article published on 01 January 2016

The majority of G0 transgenic mice are derived from mosaic embryos

scientific article published on 01 January 1993

The minipig as a platform for new technologies in toxicology

scientific article published on 31 May 2010

Tissue-specific and expression of porcine growth hormone gene in BAC transgenic mice

article

Toward designer milk

scientific article published on 01 February 1999

Toward ovine iPSCs

scientific article published on 13 September 2013

Transgene methylation in mice reflects copy number but not expression level.

scientific article published in March 2004

Transgenic animal welfare

scientific article published on 01 October 2001

Transgenic embryos and mice produced from low titre lentiviral vectors

article

Transgenic livestock made easy.

scientific article published on April 2004

Transgenic sheep designed for transplantation studies.

scientific article published in January 2009

USP18 restricts PRRSV growth through alteration of nuclear translocation of NF-κB p65 and p50 in MARC-145 cells.

scientific article

Unexpected mutations were expected and unrelated to CRISPR-Cas9 activity

scientific article published on 31 May 2018

Virus-neutralizing monoclonal antibody expressed in milk of transgenic mice provides full protection against virus-induced encephalitis.

scientific article

Zinc finger nuclease technology heralds a new era in mammalian transgenesis.

scientific article published on 16 December 2009

p21(WAF1) is component of a positive feedback loop that maintains the p53 transcriptional program.

scientific article published on 15 March 2011

p21-LacZ reporter mice reflect p53-dependent toxic insult

article

Paulina is supported by:

About Paulina

Help