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List of works by Joao Henrique G Lago

3alpha,4alpha-Epoxy-2-piperidone, a new minor derivative from leaves of Piper crassinervium Kunth (Piperaceae)

scientific article published on 01 August 2007

7-Epiclusianone, a Benzophenone Extracted from Garcinia brasiliensis (Clusiaceae), Induces Cell Cycle Arrest in G1/S Transition in A549 Cells.

scientific article published on 15 July 2015

A flavanone from Baccharis retusa (Asteraceae) prevents elastase-induced emphysema in mice by regulating NF-κB, oxidative stress and metalloproteinases

scientific article

A new minor dimmeric ester from seeds of Cassia fistula L. (Leguminosae)

scientific article published on 15 July 2011

A novel β-glucosidase from Sporidiobolus pararoseus: characterization and application in winemaking.

scientific article published on 5 August 2011

Acetylenic fatty acids from Porcelia macrocarpa (Annonaceae) against trypomastigotes of Trypanosoma cruzi: Effect of octadec-9-ynoic acid in plasma membrane electric potential

scientific article published on 30 March 2018

Alchornedine, a new anti-trypanosomal guanidine alkaloid from Alchornea glandulosa.

scientific article published on September 2014

Aldingenin derivatives from the red alga Laurencia aldingensis.

scientific article published in July 2006

Alkaloids from Porcelia macrocarpa.

scientific article

Anti-Inflammatory Derivatives with Dual Mechanism of Action from the Metabolomic Screening of Poincianella pluviosa

scientific article published on 29 November 2019

Anti-leishmanial and anti-trypanosomal potential of polygodial isolated from stem barks of Drimys brasiliensis Miers (Winteraceae).

scientific article published on 18 January 2011

Anti-leishmanial effects of purified compounds from aerial parts of Baccharis uncinella C. DC. (Asteraceae)

scientific article published on October 1, 2010

Anti-malarial, anti-trypanosomal, and anti-leishmanial activities of jacaranone isolated from Pentacalia desiderabilis (Vell.) Cuatrec. (Asteraceae).

scientific article published on 26 May 2011

Anti-trypanosomal phenolic derivatives from Baccharis uncinella

scientific article published in February 2014

Antifungal amides from Piper scutifolium and Piper hoffmanseggianum.

scientific article published on 22 November 2007

Antifungal and cytotoxic 2-acylcyclohexane-1,3-diones from Peperomia alata and P. trineura

scientific article published on 06 June 2014

Antifungal flavanones and prenylated hydroquinones from Piper crassinervium Kunth.

scientific article published in September 2003

Antileishmanial activity and immunomodulatory effect of secosubamolide, a butanolide isolated from Nectandra oppositifolia (Lauraceae)

scientific article published on 19 August 2019

Antileishmanial activity and ultrastructural changes of related tetrahydrofuran dineolignans isolated from Saururus cernuus L. (Saururaceae)

scientific article published on 08 October 2019

Antileishmanial activity and ultrastructural changes of sesquiterpene lactones isolated from Calea pinnatifida (Asteraceae)

scientific article published on 30 October 2018

Antileishmanial activity evaluation of adunchalcone, a new prenylated dihydrochalcone from Piper aduncum L.

scientific article published on 24 May 2014

Antileishmanial activity of meroditerpenoids from the macroalgae Cystoseira baccata

scientific article

Antimicrobial activity of oleanolic and ursolic acids: an update.

scientific article published on 22 February 2015

Antioxidant activity of prenylated hydroquinone and benzoic acid derivatives from Piper crassinervium Kunth

scientific article published on 18 April 2006

Antiparasitic activity and effect of casearins isolated from Casearia sylvestris on Leishmania and Trypanosoma cruzi plasma membrane.

scientific article

Antiparasitic activity of natural and semi-synthetic tirucallane triterpenoids from Schinus terebinthifolius (Anacardiaceae): structure/activity relationships

scientific article published on 05 May 2014

Antiproliferative activity of flavonoids from Croton sphaerogynus Baill. (Euphorbiaceae).

scientific article published on 17 May 2015

Antiprotozoal activity of extracts and isolated triterpenoids of 'carnauba' (Copernicia prunifera) wax from Brazil.

scientific article

Antitrypanosomal Acetylene Fatty Acid Derivatives from the Seeds of Porcelia macrocarpa (Annonaceae).

scientific article published on 7 May 2015

Antitrypanosomal Activity of Acetogenins Isolated from the Seeds of Porcelia macrocarpa Is Associated with Alterations in Both Plasma Membrane Electric Potential and Mitochondrial Membrane Potential

scientific article published on 02 May 2019

Antitrypanosomal activity and evaluation of the mechanism of action of dehydrodieugenol isolated from Nectandra leucantha (Lauraceae) and its methylated derivative against Trypanosoma cruzi.

scientific article

Antitrypanosomal activity and evaluation of the mechanism of action of diterpenes from aerial parts of Baccharis retusa (Asteraceae).

scientific article published on 18 December 2017

Antitumor activity of kielmeyera coriacea leaf constituents in experimental melanoma, tested in vitro and in vivo in syngeneic mice.

scientific article

Assessing the Chemical Composition and Antimicrobial Activity of Essential Oils from Brazilian Plants-Eremanthus erythropappus (Asteraceae), Plectrantuns barbatus, and P. amboinicus (Lamiaceae).

scientific article

Bioactivity-guided isolation of laevicarpin, an antitrypanosomal and anticryptococcal lactam from Piper laevicarpu (Piperaceae).

scientific article published on 12 April 2016

Butenolides from Nectandra oppositifolia (Lauraceae) displayed anti-Trypanosoma cruzi activity via deregulation of mitochondria

scientific article published on 09 October 2018

Camphene isolated from essential oil of Piper cernuum (Piperaceae) induces intrinsic apoptosis in melanoma cells and displays antitumor activity in vivo

scientific article published on 12 October 2015

Can macroalgae provide promising anti-tumoral compounds? A closer look at Cystoseira tamariscifolia as a source for antioxidant and anti-hepatocarcinoma compounds

scientific article

Chemical and biological evaluation of essential oils from two species of Myrtaceae - Eugenia uniflora L. and Plinia trunciflora (O. Berg) Kausel.

scientific article

Chemical composition and antimicrobial activity of essential oils from Chromolaena laevigata during flowering and fruiting stages.

scientific article

Chemical composition and cytotoxicity evaluation of essential oil from leaves of Casearia sylvestris, its main compound α-zingiberene and derivatives

scientific article published on 8 August 2013

Chemical composition and in vitro cytotoxic and antileishmanial activities of extract and essential oil from leaves of Piper cernuum

scientific article published on February 2015

Chemical composition and in vitro cytotoxic effects of the essential oil from Nectandra leucantha leaves.

scientific article

Chemical composition, seasonal variation, and biosynthetic considerations of essential oils from Baccharis microdonta and B. elaeagnoides (Asteraceae).

scientific article published on November 2010

Chemical constituents and cytotoxic evaluation of essential oils from leaves of Porcelia macrocarpa (Annonaceae).

scientific article published on February 2013

Chemical constituents derived from Drimys brasiliensis Miers (Winteraceae).

scientific article published on 28 March 2013

Chromenes from Peperomia serpens (Sw.) Loudon (Piperaceae)

scientific article published on 14 September 2006

Circadian variation and in vitro cytotoxic activity evaluation of volatile compounds from leaves of Piper regnellii (Miq) C. DC. var. regnellii (C. DC.) Yunck (Piperaceae)

scientific article published on 03 August 2017

Combined treatment with caffeic and ferulic acid from Baccharis uncinella C. DC. (Asteraceae) protects against metabolic syndrome in mice.

scientific article published on 2 February 2016

Corrigendum to "Therapeutic effect of ursolic acid in experimental visceral leishmaniasis" [Int. J. Parasitol. Drugs Drug Resist. 7 (2017) 1-11].

scientific article published on 4 April 2017

Crystal structure of De-hydro-dieugenol B methyl ether, a neolignan from Nectandra leucantha Nees and Mart (Lauraceae).

scientific article

Cycloartane triterpenoids from Guarea macrophylla.

scientific article published in June 2002

Cytotoxic and Antimicrobial Constituents from the Essential Oil of Lippia alba (Verbenaceae).

scientific article published on 12 August 2016

Erratum: A flavanone from Baccharis retusa (Asteraceae) prevents elastase-induced emphysema in mice by regulating NF-κB, oxidative stress and metalloproteinases

scientific article published on 17 September 2015

Essential oils fromSchinus terebinthifoliusleaves – chemical composition andin vitrocytotoxicity evaluation

scientific article published on August 8, 2012

Evaluation of anti-inflammatory activity of derivatives from aerial parts of Baccharis uncinella.

scientific article published in June 2011

Evidences of Herbal Medicine-Derived Natural Products Effects in Inflammatory Lung Diseases

scientific article

Flavonone treatment reverses airway inflammation and remodelling in an asthma murine model

scientific article published on April 2013

Genus xylopia (Annonaceae): chemical and biological aspects.

scientific article

Gibbilimbol analogues as antiparasitic agents--Synthesis and biological activity against Trypanosoma cruzi and Leishmania (L.) infantum.

scientific article published on 16 January 2016

Hydroalcoholic Extract and Ethyl Acetate Fraction of Leaves Decrease the Inflammatory Response to Subsp.

scientific article published on 02 October 2018

Immunomodulatory and Antileishmanial Activity of Phenylpropanoid Dimers Isolated from Nectandra leucantha

scientific article published on 2 April 2015

Intraspecific variation in the essential oils from Drimys brasiliensis leaves and stem barks

scientific article published on 01 February 2011

Isolation of an antileishmanial and antitrypanosomal flavanone from the leaves of Baccharis retusa DC. (Asteraceae).

scientific article published on 18 February 2010

Isololiolide, a carotenoid metabolite isolated from the brown alga Cystoseira tamariscifolia, is cytotoxic and able to induce apoptosis in hepatocarcinoma cells through caspase-3 activation, decreased Bcl-2 levels, increased p53 expression and PARP c

scientific article published on 26 February 2016

Jacaranone induces apoptosis in melanoma cells via ROS-mediated downregulation of Akt and p38 MAPK activation and displays antitumor activity in vivo.

scientific article

Leishmanicidal activity of an alkenylphenol from Piper malacophyllum is related to plasma membrane disruption.

scientific article published on 5 September 2012

Mechanism of Action of Thymol on Cell Membranes Investigated through Lipid Langmuir Monolayers at the Air-Water Interface and Molecular Simulation

scientific article published on 21 March 2016

Metabolite profile of Nectandra oppositifolia Nees & Mart. and assessment of antitrypanosomal activity of bioactive compounds through efficiency analyses

scientific article

Minor sesquiterpenes from the volatile oil from leaves of Guarea guidonia Sleumer (Meliaceae).

scientific article published in January 2009

Neolignans from Nectandra megapotamica (Lauraceae) Display in vitro Cytotoxic Activity and Induce Apoptosis in Leukemia Cells.

scientific article published on 15 July 2015

Neolignans from leaves of Nectandra leucantha (Lauraceae) display in vitro antitrypanosomal activity via plasma membrane and mitochondrial damages.

scientific article published on 29 August 2017

Neolignans isolated from Nectandra leucantha induce apoptosis in melanoma cells by disturbance in mitochondrial integrity and redox homeostasis

scientific article

Neolignans isolated from twigs of Ness & Mart (Lauraceae) displayed in vitro antileishmanial activity

scientific article published on 27 September 2018

Nepeta cataria L. var. citriodora (Becker) increases penile erection in rats

scientific article published on 05 August 2011

New alkenyl derivative from Piper malacophyllum and analogues: Antiparasitic activity against Trypanosoma cruzi and Leishmania infantum.

scientific article published on 29 March 2017

Phytochemical characterization of the Vochysia rufa (Vochysiaceae) extract and its effects on oxidative stress in the pancreata of streptozotocin-induced diabetic rats.

scientific article published on 5 October 2017

Plants Used in Traditional Medicine: Extracts and Secondary Metabolites Exhibiting Antileishmanial Activity

scientific article published on January 1, 2014

Polygodial, a sesquiterpene isolated from Drimys brasiliensis (Winteraceae), triggers glucocorticoid-like effects on pancreatic β-cells

scientific article published on 16 September 2016

Potential of Terpenoids and Flavonoids from Asteraceae as Anti-Inflammatory, Antitumor, and Antiparasitic Agents.

scientific article published on 12 July 2017

Predictive metabolomic signatures of end-stage renal disease: A multivariate analysis of population-based data

scientific article published on 15 June 2018

Prophylactic and therapeutic treatment with the flavonone sakuranetin ameliorates LPS-induced acute lung injury

scientific article published on 23 November 2016

Purification and characterization of an ethanol-tolerant β-glucosidase from Sporidiobolus pararoseus and its potential for hydrolysis of wine aroma precursors

scientific article published on 31 August 2013

Pyrostegia venusta heptane extract containing saturated aliphatic hydrocarbons induces apoptosis on B16F10-Nex2 melanoma cells and displays antitumor activity in vivo

scientific article published in April 2014

Report of in vitro antileishmanial properties of Iberian macroalgae.

scientific article published on 9 February 2018

Sakuranetin reverses vascular peribronchial and lung parenchyma remodeling in a murine model of chronic allergic pulmonary inflammation.

scientific article published on 14 July 2016

Secondary metabolites isolated from Piper chimonantifolium and their antifungal activity

scientific article published on 24 October 2011

Sesquiterpene Lactones from Calea pinnatifida: Absolute Configuration and Structural Requirements for Antitumor Activity

scientific article published on 30 June 2020

Soulamarin isolated from Calophyllum brasiliense (Clusiaceae) induces plasma membrane permeabilization of Trypanosoma cruzi and mytochondrial dysfunction

scientific article (publication date: 2013)

Structural crystalline characterization of sakuranetin--an antimicrobial flavanone from twigs of Baccharis retusa (Asteraceae).

scientific article published on 6 June 2014

Structurally Related Monoterpenes p-Cymene, Carvacrol and Thymol Isolated from Essential Oil from Leaves of Lippia sidoides Cham. (Verbenaceae) Protect Mice against Elastase-Induced Emphysema.

scientific article published on 20 October 2016

Structure-activity association of flavonoids in lung diseases

scientific article published on 24 March 2014

Terpenes from leaves of Guarea macrophylla (Meliaceae).

scientific article

Terpenoids from Guarea guidonia.

scientific article published in June 2002

Terpenoids from Leaves of Guarea macrophylla Display In Vitro Cytotoxic Activity and Induce Apoptosis In Melanoma Cells.

scientific article

The Correlation between Chemical Structures and Antioxidant, Prooxidant, and Antitrypanosomatid Properties of Flavonoids.

scientific article published on 2 July 2017

The Effect of Ursolic Acid on Leishmania (Leishmania) amazonensis Is Related to Programed Cell Death and Presents Therapeutic Potential in Experimental Cutaneous Leishmaniasis

scientific article

The genus Caesalpinia L. (Caesalpiniaceae): phytochemical and pharmacological characteristics.

scientific article published on 29 June 2012

The interaction of eugenol with cell membrane models at the air-water interface is modulated by the lipid monolayer composition

scientific article published on 29 July 2015

The mystery of the 'resin-of-canuaru': a medicine used by caboclos river-dwellers of the Amazon, Amazonas, Brazil.

scientific article published on 23 October 2012

The seasonal variation of the chemical composition of essential oils from Porcelia macrocarpa R.E. Fries (Annonaceae) and their antimicrobial activity

scientific article published on 01 November 2013

Therapeutic effect of ursolic acid in experimental visceral leishmaniasis

scientific article published on 08 December 2016

Treatment with triterpenic fraction purified from Baccharis uncinella leaves inhibits Leishmania (Leishmania) amazonensis spreading and improves Th1 immune response in infected mice

article

Ultrathin films of lipids to investigate the action of a flavonoid with cell membrane models.

scientific article published on 29 November 2014

Ursolic Acid Potentializes Conventional Therapy in Experimental Leishmaniasis

scientific article published on 20 October 2020

Volatile oil from Guarea macrophylla ssp. tuberculata: seasonal variation and electroantennographic detection by Hypsipyla grandella.

scientific article published on 24 January 2006

Wine aroma improvement using a β-glucosidase preparation from Aureobasidium pullulans

scientific article published on 12 December 2012

α-Pinene isolated from Schinus terebinthifolius Raddi (Anacardiaceae) induces apoptosis and confers antimetastatic protection in a melanoma model.

scientific article published on 2 July 2011

α-zingiberene, a sesquiterpene from essential oil from leaves of <i>Casearia sylvestris</i>, suppresses inflammatory angiogenesis and stimulates collagen deposition in subcutaneous implants in mice

scientific article published in 2021