List of works by Mark T Bedford

A transcriptional coregulator, SPIN·DOC, attenuates the coactivator activity of Spindlin1.

scientific article published on 23 October 2017

Acetylation of CCAR2 Establishes a BET/BRD9 Acetyl Switch in Response to Combined Deacetylase and Bromodomain Inhibition

scientific article published on 14 January 2019

Author Correction: De novo identification of essential protein domains from CRISPR-Cas9 tiling-sgRNA knockout screens

scientific article published on 25 February 2020

CARM1 methylates MED12 to regulate its RNA-binding ability

scientific article published on 19 September 2018

De novo identification of essential protein domains from CRISPR-Cas9 tiling-sgRNA knockout screens

scientific article published on 04 October 2019

Design, synthesis and biological evaluation of carboxy analogues of arginine methyltransferase inhibitor 1 (AMI-1).

scientific article published in March 2010

Developing Spindlin1 small-molecule inhibitors by using protein microarrays

scientific article

E2F1 acetylation directs p300/CBP-mediated histone acetylation at DNA double-strand breaks to facilitate repair

scientific article published on 30 October 2019

Genetic evidence for partial redundancy between the arginine methyltransferases CARM1 and PRMT6

scientific article published on 02 October 2020

Histone H3 N-terminal mimicry drives a novel network of methyl-effector interactions

scientific article published on 01 May 2021

Histone deacetylase inhibitor activity in royal jelly might facilitate caste switching in bees.

scientific article

Host Protein BAG3 is a Negative Regulator of Lassa VLP Egress

scientific article published on 13 July 2018

Identification of small-molecule enhancers of arginine methylation catalyzed by coactivator-associated arginine methyltransferase 1.

scientific article

Modular mimicry and engagement of the Hippo pathway by Marburg virus VP40: Implications for filovirus biology and budding

scientific article published on 06 January 2020

Mouse models of overexpression reveal distinct oncogenic roles for different type I protein arginine methyltransferases

article

Novel 3,5-bis(bromohydroxybenzylidene)piperidin-4-ones as coactivator-associated arginine methyltransferase 1 inhibitors: enzyme selectivity and cellular activity

scientific article published on 13 June 2011

PRMT5 C-terminal Phosphorylation Modulates a 14-3-3/PDZ Interaction Switch.

scientific article published on 28 December 2016

PRMT6 Promotes Lung Tumor Progression via the Alternate Activation of Tumor-Associated Macrophages

scientific article published on 16 October 2019

Phosphorylation of the phosphatase PTPROt at Tyr399 is a molecular switch that controls osteoclast activity and bone mass in vivo

scientific article published on 08 January 2019

Screening for histone codebreakers

scientific article published in Journal of Biological Chemistry

Synthesis and biological validation of novel synthetic histone/protein methyltransferase inhibitors

scientific article published on July 2007

TIE2-mediated tyrosine phosphorylation of H4 regulates DNA damage response by recruiting ABL1.

scientific article published on April 2016

Unique Features of Human Protein Arginine Methyltransferase 9 (PRMT9) and Its Substrate RNA Splicing Factor SF3B2

scientific article

epigenetic multiple ligands: mixed histone/protein methyltransferase, acetyltransferase, and class III deacetylase (sirtuin) inhibitors.

scientific article

Paulina is supported by:

About Paulina

Help