List of works - Elke Genersch

A cell culture model for Nosema ceranae and Nosema apis allows new insights into the life cycle of these important honey bee-pathogenic microsporidia

scientific article published on 30 September 2010

American Foulbrood in honeybees and its causative agent, Paenibacillus larvae

scientific article

Anti-Virulence Strategy against the Honey Bee Pathogenic Bacterium Paenibacillus larvae via Small Molecule Inhibitors of the Bacterial Toxin Plx2A

scientific article published on 01 September 2021

Biochemical characterization of different genotypes of Paenibacillus larvae subsp. larvae, a honey bee bacterial pathogen

scientific article

Biological Role of Paenilarvins, Iturin-Like Lipopeptide Secondary Metabolites Produced by the Honey Bee Pathogen Paenibacillus larvae

scientific article

Biological effects of paenilamicin, a secondary metabolite antibiotic produced by the honey bee pathogenic bacterium Paenibacillus larvae ⬇️

scientific article published on 16 July 2014

Biology of Paenibacillus larvae, a deadly pathogen of honey bee larvae

scientific article

Characterization of the toxin Plx2A, a RhoA-targeting ADP-ribosyltransferase produced by the honey bee pathogen Paenibacillus larvae

scientific article

Country-specific effects of neonicotinoid pesticides on honey bees and wild bees.

scientific article published in June 2017

Deformed wing virus

scientific article

Deformed wing virus: replication and viral load in mites (Varroa destructor).

scientific article published in February 2009

Detection of Deformed wing virus, a honey bee viral pathogen, in bumble bees (Bombus terrestris and Bombus pascuorum) with wing deformities

scientific article

Detection of viral sequences in semen of honeybees (Apis mellifera): evidence for vertical transmission of viruses through drones

scientific article published on 21 April 2006

Development of a loop-mediated isothermal amplification (LAMP) and a direct LAMP for the specific detection of Nosema ceranae, a parasite of honey bees

scientific article published on 12 October 2020

Development of a rapid and sensitive RT-PCR method for the detection of deformed wing virus, a pathogen of the honeybee (Apis mellifera).

scientific article

Direct Evidence for Infection of Varroa destructor Mites with the Bee-Pathogenic Deformed Wing Virus Variant B - but Not Variant A - via Fluorescence-in situ-Hybridization Analysis

scientific article published on 09 December 2020

Elucidation of sevadicin, a novel non-ribosomal peptide secondary metabolite produced by the honey bee pathogenic bacterium Paenibacillus larvae

scientific article

Emerging and re-emerging viruses of the honey bee (Apis mellifera L.).

scientific article

Erratum to: Unity in defence: honeybee workers exhibit conserved molecular responses to diverse pathogens

scientific article published on 23 March 2017

Evidence for damage-dependent hygienic behaviour towards Varroa destructor-parasitised brood in the western honey bee, Apis mellifera.

scientific article published in January 2012

Evidence for emerging parasites and pathogens influencing outbreaks of stress-related diseases like chalkbrood.

scientific article published on 30 August 2011

Five-year cohort study of Nosema spp. in Germany: does climate shape virulence and assertiveness of Nosema ceranae?

scientific article published on 12 March 2010

Fluorescence in situ hybridization (FISH) analysis of the interactions between honeybee larvae and Paenibacillus larvae, the causative agent of American foulbrood of honeybees (Apis mellifera).

scientific article published on 4 March 2008

Honey bee disease overview.

scientific article published on 11 November 2009

Honey bee larval peritrophic matrix degradation during infection with Paenibacillus larvae, the aetiological agent of American foulbrood of honey bees, is a key step in pathogenesis

scientific article

Honey bee pathology: current threats to honey bees and beekeeping

scientific article

Horizontal transmission of deformed wing virus: pathological consequences in adult bees (Apis mellifera) depend on the transmission route

scientific article published on 21 October 2010

How to kill the honey bee larva: genomic potential and virulence mechanisms of Paenibacillus larvae

scientific article

Identification and characterization of two novel toxins expressed by the lethal honey bee pathogen Paenibacillus larvae, the causative agent of American foulbrood

scientific article published on 29 August 2013

Identification and functional analysis of the S-layer protein SplA of Paenibacillus larvae, the causative agent of American Foulbrood of honey bees.

scientific article

Identification of candidate agents active against N. ceranae infection in honey bees: establishment of a medium throughput screening assay based on N. ceranae infected cultured cells

scientific article

In vivo evolution of viral virulence: switching of deformed wing virus between hosts results in virulence changes and sequence shifts

scientific article published on 02 December 2018

Integrin alphavbeta3 binding to human alpha5-laminins facilitates FGF-2- and VEGF-induced proliferation of human ECV304 carcinoma cells

scientific article published on March 2003

Involvement of secondary metabolites in the pathogenesis of the American foulbrood of honey bees caused by Paenibacillus larvae

scientific article published on 23 April 2015

Laminin isoforms differentially regulate adhesion, spreading, proliferation, and ERK activation of beta1 integrin-null cells

scientific article published on October 2004

Laminin-1 promotes angiogenesis in synergy with fibroblast growth factor by distinct regulation of the gene and protein expression profile in endothelial cells.

scientific article published on 25 March 2004

Long-Term Temporal Trends of Nosema spp. Infection Prevalence in Northeast Germany: Continuous Spread of Nosema ceranae, an Emerging Pathogen of Honey Bees (Apis mellifera), but No General Replacement of Nosema apis

scientific article published on 06 July 2017

Molecular differentiation of Nosema apis and Nosema ceranae based on species-specific sequence differences in a protein coding gene

scientific article

Molecular pathogenesis of American Foulbrood: how Paenibacillus larvae kills honey bee larvae.

scientific article published on 30 April 2015

Morphologic and molecular data help adopting the insect-pathogenic nephridiophagids (Nephridiophagidae) among the early diverging fungal lineages, close to the Chytridiomycota

scientific article published on 10 July 2017

Negative correlation between individual-insect-level virulence and colony-level virulence of Paenibacillus larvae, the etiological agent of American foulbrood of honeybees

scientific article published on 20 March 2009

Opposing roles of integrin alpha6Abeta1 and dystroglycan in laminin-mediated extracellular signal-regulated kinase activation

scientific article published on 6 February 2003

Paenibacillus larvae and American foulbrood in honeybees.

scientific article published on January 2007

Paenibacillus larvae chitin-degrading protein PlCBP49 is a key virulence factor in American Foulbrood of honey bees

scientific article

Paenilamicin - Struktur und Biosynthese eines hybriden Polyketid-/nichtribosomalen Peptidantibiotikums des bienenpathogenen BakteriumsPaenibacillus larvae

Paenilamicin: structure and biosynthesis of a hybrid nonribosomal peptide/polyketide antibiotic from the bee pathogen Paenibacillus larvae

scientific article published on 30 July 2014

Production of the catechol type siderophore bacillibactin by the honey bee pathogen Paenibacillus larvae

scientific article

Proposal to reclassify Paenibacillus larvae subsp. pulvifaciens DSM 3615 (ATCC 49843) as Paenibacillus larvae subsp. larvae. Results of a comparative biochemical and genetic study.

scientific article published in November 2004

Proteome analysis of Paenibacillus larvae reveals the existence of a putative S-layer protein

scientific article published on 4 January 2012

RT-PCR analysis of Deformed wing virus in honeybees (Apis mellifera) and mites (Varroa destructor)

scientific article

Reclassification of Paenibacillus larvae subsp. pulvifaciens and Paenibacillus larvae subsp. larvae as Paenibacillus larvae without subspecies differentiation.

scientific article

Significant, but not biologically relevant: Nosema ceranae infections and winter losses of honey bee colonies

scientific article published in 2023

Special Issue: Honey Bee Viruses

scientific article published in October 2015

Standard methods for American foulbrood research

article by Dirk C de Graaf et al published January 2013 in Journal of Apicultural Research and Bee World

Standard methods for Nosema research

article

Standard methods for molecular research inApis mellifera

article

Standard methods for virus research inApis mellifera

article by Joachim R de Miranda et al published January 2013 in Journal of Apicultural Research and Bee World

Strain- and genotype-specific differences in virulence of Paenibacillus larvae subsp. larvae, a bacterial pathogen causing American foulbrood disease in honeybees

scientific article

Swarming motility and biofilm formation of Paenibacillus larvae, the etiological agent of American Foulbrood of honey bees (Apis mellifera).

scientific article published on 11 June 2018

The German bee monitoring project: a long term study to understand periodically high winter losses of honey bee colonies

article

The biological role of the enigmatic C3larvinAB toxin of the honey bee pathogenic bacterium Paenibacillus larvae

scientific article published on 26 June 2019

Total Synthesis and Biological Evaluation of Paenilamicins from the Honey Bee Pathogen Paenibacillus larvae

scientific article published on 30 December 2021

Unity in defence: honeybee workers exhibit conserved molecular responses to diverse pathogens

scientific article

Use of suppression subtractive hybridization to identify genetic differences between differentially virulent genotypes of Paenibacillus larvae, the etiological agent of American Foulbrood of honeybees.

scientific article published on 12 June 2009

Viruses of commercialized insect pollinators

scientific article

Widespread dispersal of the microsporidian Nosema ceranae, an emergent pathogen of the western honey bee, Apis mellifera.

scientific article published on 12 March 2007

List of works by Elke Genersch

A cell culture model for Nosema ceranae and Nosema apis allows new insights into the life cycle of these important honey bee-pathogenic microsporidia

American Foulbrood in honeybees and its causative agent, Paenibacillus larvae

Anti-Virulence Strategy against the Honey Bee Pathogenic Bacterium Paenibacillus larvae via Small Molecule Inhibitors of the Bacterial Toxin Plx2A

Biochemical characterization of different genotypes of Paenibacillus larvae subsp. larvae, a honey bee bacterial pathogen

Biological Role of Paenilarvins, Iturin-Like Lipopeptide Secondary Metabolites Produced by the Honey Bee Pathogen Paenibacillus larvae

Biological effects of paenilamicin, a secondary metabolite antibiotic produced by the honey bee pathogenic bacterium Paenibacillus larvae ⬇️

Biology of Paenibacillus larvae, a deadly pathogen of honey bee larvae

Characterization of the toxin Plx2A, a RhoA-targeting ADP-ribosyltransferase produced by the honey bee pathogen Paenibacillus larvae

Country-specific effects of neonicotinoid pesticides on honey bees and wild bees.

Deformed wing virus

Deformed wing virus: replication and viral load in mites (Varroa destructor).

Detection of Deformed wing virus, a honey bee viral pathogen, in bumble bees (Bombus terrestris and Bombus pascuorum) with wing deformities

Detection of viral sequences in semen of honeybees (Apis mellifera): evidence for vertical transmission of viruses through drones

Development of a loop-mediated isothermal amplification (LAMP) and a direct LAMP for the specific detection of Nosema ceranae, a parasite of honey bees

Development of a rapid and sensitive RT-PCR method for the detection of deformed wing virus, a pathogen of the honeybee (Apis mellifera).

Direct Evidence for Infection of <i>Varroa destructor</i> Mites with the Bee-Pathogenic Deformed Wing Virus Variant B - but Not Variant A - via Fluorescence-<i>in situ</i>-Hybridization Analysis

Elucidation of sevadicin, a novel non-ribosomal peptide secondary metabolite produced by the honey bee pathogenic bacterium Paenibacillus larvae

Emerging and re-emerging viruses of the honey bee (Apis mellifera L.).

Erratum to: Unity in defence: honeybee workers exhibit conserved molecular responses to diverse pathogens

Evidence for damage-dependent hygienic behaviour towards Varroa destructor-parasitised brood in the western honey bee, Apis mellifera.

Evidence for emerging parasites and pathogens influencing outbreaks of stress-related diseases like chalkbrood.

Five-year cohort study of Nosema spp. in Germany: does climate shape virulence and assertiveness of Nosema ceranae?

Fluorescence in situ hybridization (FISH) analysis of the interactions between honeybee larvae and Paenibacillus larvae, the causative agent of American foulbrood of honeybees (Apis mellifera).

Honey bee disease overview.

Honey bee larval peritrophic matrix degradation during infection with Paenibacillus larvae, the aetiological agent of American foulbrood of honey bees, is a key step in pathogenesis

Honey bee pathology: current threats to honey bees and beekeeping

Horizontal transmission of deformed wing virus: pathological consequences in adult bees (Apis mellifera) depend on the transmission route

How to kill the honey bee larva: genomic potential and virulence mechanisms of Paenibacillus larvae

Identification and characterization of two novel toxins expressed by the lethal honey bee pathogen Paenibacillus larvae, the causative agent of American foulbrood

Identification and functional analysis of the S-layer protein SplA of Paenibacillus larvae, the causative agent of American Foulbrood of honey bees.

Identification of candidate agents active against N. ceranae infection in honey bees: establishment of a medium throughput screening assay based on N. ceranae infected cultured cells

In vivo evolution of viral virulence: switching of deformed wing virus between hosts results in virulence changes and sequence shifts

Integrin alphavbeta3 binding to human alpha5-laminins facilitates FGF-2- and VEGF-induced proliferation of human ECV304 carcinoma cells

Involvement of secondary metabolites in the pathogenesis of the American foulbrood of honey bees caused by Paenibacillus larvae

Laminin isoforms differentially regulate adhesion, spreading, proliferation, and ERK activation of beta1 integrin-null cells

Laminin-1 promotes angiogenesis in synergy with fibroblast growth factor by distinct regulation of the gene and protein expression profile in endothelial cells.

Long-Term Temporal Trends of Nosema spp. Infection Prevalence in Northeast Germany: Continuous Spread of Nosema ceranae, an Emerging Pathogen of Honey Bees (Apis mellifera), but No General Replacement of Nosema apis

Molecular differentiation of Nosema apis and Nosema ceranae based on species-specific sequence differences in a protein coding gene

Molecular pathogenesis of American Foulbrood: how Paenibacillus larvae kills honey bee larvae.

Morphologic and molecular data help adopting the insect-pathogenic nephridiophagids (Nephridiophagidae) among the early diverging fungal lineages, close to the Chytridiomycota

Negative correlation between individual-insect-level virulence and colony-level virulence of Paenibacillus larvae, the etiological agent of American foulbrood of honeybees

Opposing roles of integrin alpha6Abeta1 and dystroglycan in laminin-mediated extracellular signal-regulated kinase activation

Paenibacillus larvae and American foulbrood in honeybees.

Paenibacillus larvae chitin-degrading protein PlCBP49 is a key virulence factor in American Foulbrood of honey bees

Paenilamicin - Struktur und Biosynthese eines hybriden Polyketid-/nichtribosomalen Peptidantibiotikums des bienenpathogenen BakteriumsPaenibacillus larvae

Paenilamicin: structure and biosynthesis of a hybrid nonribosomal peptide/polyketide antibiotic from the bee pathogen Paenibacillus larvae

Production of the catechol type siderophore bacillibactin by the honey bee pathogen Paenibacillus larvae

Proposal to reclassify Paenibacillus larvae subsp. pulvifaciens DSM 3615 (ATCC 49843) as Paenibacillus larvae subsp. larvae. Results of a comparative biochemical and genetic study.

Proteome analysis of Paenibacillus larvae reveals the existence of a putative S-layer protein

RT-PCR analysis of Deformed wing virus in honeybees (Apis mellifera) and mites (Varroa destructor)

Reclassification of Paenibacillus larvae subsp. pulvifaciens and Paenibacillus larvae subsp. larvae as Paenibacillus larvae without subspecies differentiation.

Significant, but not biologically relevant: Nosema ceranae infections and winter losses of honey bee colonies

Special Issue: Honey Bee Viruses

Standard methods for American foulbrood research

Standard methods for Nosema research

Standard methods for molecular research inApis mellifera

Standard methods for virus research inApis mellifera

Strain- and genotype-specific differences in virulence of Paenibacillus larvae subsp. larvae, a bacterial pathogen causing American foulbrood disease in honeybees

Swarming motility and biofilm formation of Paenibacillus larvae, the etiological agent of American Foulbrood of honey bees (Apis mellifera).

The German bee monitoring project: a long term study to understand periodically high winter losses of honey bee colonies

The biological role of the enigmatic C3larvinAB toxin of the honey bee pathogenic bacterium Paenibacillus larvae

Total Synthesis and Biological Evaluation of Paenilamicins from the Honey Bee Pathogen <i>Paenibacillus larvae</i>

Unity in defence: honeybee workers exhibit conserved molecular responses to diverse pathogens

Use of suppression subtractive hybridization to identify genetic differences between differentially virulent genotypes of Paenibacillus larvae, the etiological agent of American Foulbrood of honeybees.

Viruses of commercialized insect pollinators

Widespread dispersal of the microsporidian Nosema ceranae, an emergent pathogen of the western honey bee, Apis mellifera.