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List of works by Kevin G Murphy

A kisspeptin-10 analog with greater in vivo bioactivity than kisspeptin-10.

scientific article

A role for arcuate cocaine and amphetamine-regulated transcript in hyperphagia, thermogenesis, and cold adaptation.

scientific article published on 18 July 2003

A role for metalloendopeptidases in the breakdown of the gut hormone, PYY 3-36.

scientific article

AAV mediated expression of anti-sense neuropeptide Y cRNA in the arcuate nucleus of rats results in decreased weight gain and food intake.

scientific article published in February 2005

Administration of kisspeptin-54 into discrete regions of the hypothalamus potently increases plasma luteinising hormone and testosterone in male adult rats.

scientific article

Alarin stimulates food intake and gonadotrophin release in male rats.

scientific article

An observed rise in γ-hydroxybutyrate-associated deaths in London: Evidence to suggest a possible link with concomitant rise in chemsex.

scientific article published on 2 December 2016

Are all fats created equal?

scientific article published on 01 January 2006

Can neuropeptides treat obesity? A review of neuropeptides and their potential role in the treatment of obesity ⬇️

scientific article published on December 1, 2013

Cannabinoid concentrations detected in fatal road traffic collision victims compared with a population of other postmortem cases.

scientific article published on 3 August 2015

Central administration of orexin A suppresses basal and domperidone stimulated plasma prolactin

Central and peripheral administration of human relaxin-2 to adult male rats inhibits food intake

scientific article published on 01 December 2010

Central and peripheral administration of kisspeptin-10 stimulates the hypothalamic-pituitary-gonadal axis.

scientific article published in October 2004

Changes in gut hormones and leptin in military personnel during operational deployment in Afghanistan.

scientific article published on 22 January 2015

Characterization and distribution of prolactin releasing peptide (PrRP) binding sites in the rat--evidence for a novel binding site subtype in cardiac and skeletal muscle.

scientific article

Characterization of Ghrelin-Like Immunoreactivity in Human Plasma

scientific article published on 18 January 2005

Chronic administration of NMU into the paraventricular nucleus stimulates the HPA axis but does not influence food intake or body weight.

scientific article published in October 2004

Chronic subcutaneous administration of kisspeptin-54 causes testicular degeneration in adult male rats

scientific article published on 20 June 2006

Circulating pancreatic polypeptide concentrations predict visceral and liver fat content.

scientific article

Cocaine- and amphetamine-regulated transcript, glucagon-like peptide-1 and corticotrophin releasing factor inhibit feeding via agouti-related protein independent pathways in the rat

scientific article published on 01 June 2000

Comparison of the utility of Cocaine- and Amphetamine-Regulated Transcript (CART), chromogranin A, and chromogranin B in neuroendocrine tumor diagnosis and assessment of disease progression.

scientific article published on 9 February 2015

Constant hepatic ATP concentrations during prolonged fasting and absence of effects of Cerbomed Nemos® on parasympathetic tone and hepatic energy metabolism.

scientific article published on 25 October 2017

Coordinated changes in energy intake and expenditure following hypothalamic administration of neuropeptides involved in energy balance.

scientific article published on 2 June 2009

Correction: Mechanistic insights into the more potent effect of KP-54 compared to KP-10 in vivo.

scientific article

Current models and strategies in the development of antiobesity drugs ⬇️

scientific article published on December 1, 2011

Detailed characterization of a long-term rodent model of critical illness and recovery

scientific article

Distribution of fluorescence following injection of recombinant adeno-associated virus encoding green fluorescent protein into the paraventricular nucleus

scientific article published in February 2003

Editorial overview: Endocrine and metabolic diseases: Waistline weapons: new therapeutic avenues for the treatment of obesity and metabolic disease

scientific article published on 10 November 2015

Effects of Chronic Central Nervous System Administration of Agouti-Related Protein in Pair-Fed Animals

scientific article published on 01 February 2001

Effects of galanin-like peptide on food intake and the hypothalamo-pituitary-thyroid axis

scientific article

Effects of targeted delivery of propionate to the human colon on appetite regulation, body weight maintenance and adiposity in overweight adults ⬇️

scientific article

Elevated cocaine- and amphetamine-regulated transcript immunoreactivity in the circulation of patients with neuroendocrine malignancy

scientific article published on 22 January 2008

Endocrinology: the next 60 years

scientific article published on July 2006

Energy expenditure, nutritional status, body composition and physical fitness of Royal Marines during a 6-month operational deployment in Afghanistan

article

Erythropoietin administration in humans causes a marked and prolonged reduction in circulating hepcidin

scientific article

GPRC6a is not required for the effects of a high-protein diet on body weight in mice

scientific article published on 9 May 2015

Ghrelin Enhances Appetite and Increases Food Intake in Humans ⬇️

scientific article published on December 1, 2001

Ghrelin stimulates insulin-induced glucose uptake in adipocytes.

scientific article

Ghrelin, appetite and critical illness

scientific article published on April 2012

Gut hormones and the regulation of energy homeostasis

scientific article

Gut hormones: the future of obesity treatment?

scientific article

Gut peptides in the regulation of food intake and energy homeostasis

scientific article

Hepcidin levels in diabetes mellitus and polycystic ovary syndrome ⬇️

scientific article published on August 19, 2013

Hypothalamic cocaine- and amphetamine-regulated transcript (CART) and agouti-related protein (AgRP) neurons coexpress the NOP1 receptor and nociceptin alters CART and AgRP release

scientific article published on 12 May 2005

Hypothalamic injection of oxyntomodulin suppresses circulating ghrelin-like immunoreactivity

scientific article

Identification of the Hormone Kisspeptin in Amniotic Fluid

scientific article published on 26 March 2010

Impact of ghrelin on body composition and muscle function in a long-term rodent model of critical illness

scientific article published on 10 August 2017

Impaired circulating glucagon-like peptide-1 response to oral glucose in women with previous gestational diabetes.

scientific article published in January 2005

Implantation of fibre encapsulated RIN 1056a cells transfected with NPY cDNA into the lateral ventricle of rats alters body weight.

scientific article published on 3 October 2005

Improved diagnostic accuracy for neuroendocrine neoplasms using two chromogranin A assays

scientific article published on 01 June 2012

Investigation of Structure-Activity Relationships of Oxyntomodulin (Oxm) Using Oxm Analogs

scientific article published on 12 December 2008

Kisspeptin is released from human prostate cancer cell lines but plasma kisspeptin is not elevated in patients with prostate cancer.

scientific article published in June 2010

Kisspeptin-54 at high doses acutely induces testicular degeneration in adult male rats via central mechanisms.

scientific article published on February 2009

Kisspeptin-54 stimulates gonadotropin release most potently during the preovulatory phase of the menstrual cycle in women

scientific article

Kisspeptin-54 stimulates the hypothalamic-pituitary gonadal axis in human males

scientific article published on 20 September 2005

Kisspeptins: regulators of metastasis and the hypothalamic-pituitary-gonadal axis.

scientific article

L-Arginine Increases Postprandial Circulating GLP-1 and PYY Levels in Humans

scientific article published on 01 November 2018

L-arginine promotes gut hormone release and reduces food intake in rodents.

scientific article published on 11 February 2016

L-cysteine suppresses ghrelin and reduces appetite in rodents and humans

scientific article

Learning curve of vessel cannulation in rats using cumulative sum analysis.

scientific article published in July 2014

Leptin fails to blunt the lipopolysaccharide-induced activation of the hypothalamic-pituitary-adrenal axis in rats.

scientific article published on 22 April 2014

Live Birth in Sex-Reversed XY Mice Lacking the Nuclear Receptor Dax1

scientific article published on 03 February 2020

Mechanistic insights into the more potent effect of KP-54 compared to KP-10 in vivo.

scientific article

Mephedrone use is increasing in London

scientific article published on 01 April 2016

Microinjection of galanin-like peptide into the medial preoptic area stimulates food intake in adult male rats.

scientific article published in October 2006

Misuse of gabapentin and pregabalin may be underestimated

scientific article published on 21 November 2017

Models and Strategies in the Development of Antiobesity Drugs ⬇️

scientific article published on July 16, 2013

Modulation of the hypothalamic-pituitary-gonadal axis by selective ligands of the KISS1R.

scientific article published on April 2010

Neuromedin B stimulates the hypothalamic-pituitary-gonadal axis in male rats.

scientific article published on 10 October 2013

Neuromedin U has a physiological role in the regulation of food intake and partially mediates the effects of leptin

Overexpression of CART in the PVN increases food intake and weight gain in rats

scientific article

Paraventricular nucleus administration of calcitonin gene-related peptide inhibits food intake and stimulates the hypothalamo-pituitary-adrenal axis

scientific article published in April 2003

Peptides and their potential role in the treatment of diabetes and obesity

scientific article published on 10 November 2011

Peripheral and central administration of xenin and neurotensin suppress food intake in rodents.

scientific article published on 12 February 2009

Peripheral influences on central melanocortin neurons.

scientific article

Plasma hepcidin levels are elevated but responsive to erythropoietin therapy in renal disease

scientific article (publication date: May 2009)

Plasma kisspeptin is raised in patients with gestational trophoblastic neoplasia and falls during treatment

scientific article published on 06 June 2006

Preanalytical Factors Affecting RIA Measurement of Plasma Kisspeptin

scientific article published on 01 March 2008

Prokineticin 2 is a hypothalamic neuropeptide that potently inhibits food intake

scientific article

Pyroglutamylated RFamide peptide 43 stimulates the hypothalamic-pituitary-gonadal axis via gonadotropin-releasing hormone in rats.

scientific article published on 5 June 2008

Quantification and synthesis of cocaine- and amphetamine-regulated transcript peptide (79-102)-like immunoreactivity and mRNA in rat tissues

scientific article published on 01 September 2000

Quantification of rat kisspeptin using a novel radioimmunoassay

scientific article

Quantitative approaches to energy and glucose homeostasis: machine learning and modelling for precision understanding and prediction

scientific article published on 24 January 2018

Randomised clinical study: inulin short-chain fatty acid esters for targeted delivery of short-chain fatty acids to the human colon. ⬇️

scientific article published on 28 July 2016

Relative Importance of the Arcuate and Anteroventral Periventricular Kisspeptin Neurons in Control of Puberty and Reproductive Function in Female Rats

scientific article published on 15 April 2015

Relaxin-3 stimulates the neuro-endocrine stress axis via corticotrophin-releasing hormone

scientific article published on 12 May 2014

Resection of the large bowel suppresses hunger and food intake and modulates gastrointestinal fermentation.

scientific article published in August 2016

Subcutaneous injection of kisspeptin-54 acutely stimulates gonadotropin secretion in women with hypothalamic amenorrhea, but chronic administration causes tachyphylaxis

scientific article published on 9 October 2009

Subcutaneous oxyntomodulin analogue administration reduces body weight in lean and obese rodents.

scientific article published on 8 June 2010

Supraphysiological doses of intravenous PYY 3-36 cause nausea, but no additional reduction in food intake

scientific article published on 01 January 2008

Sustained appetite improvement in malnourished dialysis patients by daily ghrelin treatment

scientific article published on 22 April 2009

Targeting gastrointestinal nutrient sensing mechanisms to treat obesity

scientific article published on 10 August 2017

The L-Cell in Nutritional Sensing and the Regulation of Appetite

scientific article

The central effects of thyroid hormones on appetite

scientific article

The effects of centrally administered apelin-13 on food intake, water intake and pituitary hormone release in rats

scientific article (publication date: 15 March 2002)

The effects of kisspeptin-10 on reproductive hormone release show sexual dimorphism in humans

scientific article published on 5 October 2011

The effects of kisspeptin-54 on blood pressure in humans and plasma kisspeptin concentrations in hypertensive diseases of pregnancy

scientific article

The effects of neurokinin B upon gonadotrophin release in male rodents.

scientific article published on 23 December 2009

The effects of pancreatic polypeptide on locomotor activity and food intake in mice

scientific article published on 09 September 2008

The gonadotrophic response of Royal Marines during an operational deployment in Afghanistan.

scientific article published on 23 January 2015

The homeostatic dynamics of feeding behaviour identify novel mechanisms of anorectic agents

scientific article published on 05 December 2019

The hypothalamic melanocortin system stimulates the hypothalamo-pituitary-adrenal axis in vitro and in vivo in male rats

scientific article published in April 2002

The neuroendocrine physiology of kisspeptin in the human

scientific article published on March 2007

The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone secretion

scientific article (publication date: November 2000)

The physiological role of arcuate kisspeptin neurons in the control of reproductive function in female rats.

scientific article published on 11 December 2013

The short chain fatty acid propionate stimulates GLP-1 and PYY secretion via free fatty acid receptor 2 in rodents.

scientific article published on 11 August 2014

The thyroid hormone derivative 3-iodothyronamine increases food intake in rodents.

scientific article published on 29 July 2008

l-phenylalanine modulates gut hormone release and glucose tolerance, and suppresses food intake through the calcium-sensing receptor in rodents

scientific article published on 13 July 2017

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