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List of works by Kristoffer Hellstrand

5-Propyl-2-deoxyuridine induced interference with glycosylation in herpes simplex virus infected cells. Nature of PdU-induced modifications of N-linked glycans.

scientific article

A cell-to-cell mediated interaction involving monocytes and non-T/CD16+ natural killer (NK) cells is required for histamine H2-receptor-mediated NK-cell activation.

scientific article published on May 1990

A model explaining the correlations between IL28B-related genotypes, hepatitis C virus genotypes, and viral RNA levels.

scientific article published on 29 September 2010

A proinflammatory peptide from Helicobacter pylori activates monocytes to induce lymphocyte dysfunction and apoptosis

scientific article

A proinflammatory peptide from Helicobacter pylori activates monocytes to induce lymphocyte dysfunction and apoptosis.

scientific article published in May 2006

Absence of cytomegalovirus in high-coverage DNA sequencing of human glioblastoma multiforme.

scientific article published on 7 July 2014

Accumulation of natural killer cells after hepatic artery embolisation in the midgut carcinoid syndrome.

scientific article published on March 1995

Activation of cytotoxic lymphocytes by interferon-alpha: role of oxygen radical-producing mononuclear phagocytes.

scientific article published on 10 September 2004

Acute mental stress but not enforced muscle activity transiently increases natural cytotoxicity in spontaneously hypertensive rats

scientific article published on 01 August 1996

Addition of histamine to interleukin 2 treatment augments type 1 T-cell responses in patients with melanoma in vivo: immunologic results from a randomized clinical trial of interleukin 2 with or without histamine (MP 104).

scientific article published on January 2005

Adjuvant histamine in cancer immunotherapy.

scientific article published in February 2000

Alleviating oxidative stress in cancer immunotherapy: a role for histamine?

scientific article

An immunopharmacological analysis of adrenaline-induced suppression of human natural killer cell cytotoxicity

scientific article published on 01 January 1989

Anthracycline-based consolidation may determine outcome of post-consolidation immunotherapy in AML

scientific article published on 17 April 2019

Anti-Leukemic Properties of Histamine in Monocytic Leukemia: The Role of NOX2.

scientific article published on 18 June 2018

Association between interleukin-28B-related genetic variants and liver histopathology differs between hepatitis C virus genotypes.

scientific article published on 6 June 2012

Cell-to-cell mediated inhibition of natural killer cell proliferation by monocytes and its regulation by histamine H2-receptors

scientific article published on 01 December 1991

Chronic intracerebroventricular administration of beta-endorphin augments natural killer cell cytotoxicity in rats

scientific article published on 01 April 1996

Chronic myeloid leukemic cells trigger poly(ADP-ribose) polymerase-dependent inactivation and cell death in lymphocytes.

scientific article published on 16 October 2012

Clinical and immunological evaluation of patients low in single or multiple IgG subclasses

scientific article published on 01 January 1986

Combined treatment with histamine dihydrochloride, interleukin-2 and interferon-alpha in patients with metastatic melanoma.

scientific article

Complete remission after the first cycle of induction chemotherapy determines the clinical efficacy of relapse-preventive immunotherapy in acute myeloid leukaemia

scientific article published on 18 December 2019

Cutting edge: Antioxidative properties of myeloid dendritic cells: protection of T cells and NK cells from oxygen radical-induced inactivation and apoptosis

scientific article published on 01 July 2007

Cytomegalovirus Serostatus Affects Autoreactive NK Cells and Outcomes of IL2-Based Immunotherapy in Acute Myeloid Leukemia

scientific article published on 06 July 2018

Differential effects of histamine receptor antagonists on human natural killer cell activity.

scientific article published in January 1987

Duration and mechanisms of the increased natural cytotoxicity seen after chronic voluntary exercise in rats

scientific article published on 01 August 1997

Dynamic tailoring of treatment durations improves efficiency of hepatitis C treatment with pegylated interferon and ribavirin.

scientific article published on 16 October 2012

Dynamics of cytotoxic T cell subsets during immunotherapy predicts outcome in acute myeloid leukemia

scientific article published on 05 February 2016

Dynamics of myeloid cell populations during relapse-preventive immunotherapy in acute myeloid leukemia.

scientific article published on 24 February 2017

Early determination of hepatitis C virus RNA may help to decide the duration of therapy for chronic hepatitis C virus genotype 2/3 infection

scientific article published on 28 December 2010

Early quantification of HCV core antigen may help to determine the duration of therapy for chronic genotype 2 or 3 HCV infection

scientific article published on 24 November 2011

Early results of a trial of the Oka-strain varicella vaccine in children with leukaemia or other malignancies in Sweden.

scientific article published on January 1985

Enhancement of human natural killer cell cytotoxicity by serotonin: role of non-T/CD16+ NK cells, accessory monocytes, and 5-HT1A receptors

scientific article published on 01 April 1990

Enhancement of natural immunity seen after voluntary exercise in rats. Role of central opioid receptors.

scientific article published in February 2000

Evaluation of depression as a risk factor for treatment failure in chronic hepatitis C.

scientific article

Evidence for a beta-adrenoceptor-mediated regulation of human natural killer cells

scientific article published on 01 June 1985

Hepatitis C treatment response kinetics and impact of baseline predictors

scientific article published in June 2011

Histamine H2-receptor-mediated regulation of human natural killer cell activity.

scientific article

Histamine and cytokine therapy

scientific article published on 01 January 1998

Histamine and interleukin-2 in acute myelogenous leukemia

scientific article published on 01 November 1997

Histamine and the Response to IFN-α in Chronic Hepatitis C

scientific article published on January 1, 1998

Histamine dihydrochloride and interleukin-2 in acute myeloid leukemia--background and results.

scientific article published on April 2009

Histamine dihydrochloride and low-dose interleukin-2 as post-consolidation immunotherapy in acute myeloid leukemia.

scientific article published on September 2009

Histamine in cancer immunotherapy: a preclinical background.

scientific article

Histamine in immunotherapy of advanced melanoma: a pilot study

scientific article published on 01 December 1994

Histamine inhibits neutrophil NADPH oxidase activity triggered by the lipoxin A4 receptor-specific peptide agonist Trp-Lys-Tyr-Met-Val-Met.

scientific article published in September 2003

Histamine promotes the development of monocyte-derived dendritic cells and reduces tumor growth by targeting the myeloid NADPH oxidase

scientific article

Histamine protects T cells and natural killer cells against oxidative stress

scientific article published on 01 October 1999

Histamine targets myeloid-derived suppressor cells and improves the anti-tumor efficacy of PD-1/PD-L1 checkpoint blockade

scientific article published on 12 October 2018

Histamine, cimetidine and colorectal cancer

scientific article published on 01 April 1996

Histamine: a novel approach to cancer immunotherapy.

scientific article

Histaminergic regulation of antibody-dependent cellular cytotoxicity of granulocytes, monocytes, and natural killer cells

scientific article published on 01 March 1994

Histaminergic regulation of interferon-gamma (IFN-gamma) production by human natural killer (NK) cells

scientific article published on 01 August 1996

Histaminergic regulation of natural killer cell-mediated clearance of tumour cells in mice

scientific article published on 01 January 1996

IL28B polymorphisms predict reduction of HCV RNA from the first day of therapy in chronic hepatitis C.

scientific article published on 25 February 2011

IP-10 predicts the first phase decline of HCV RNA and overall viral response to therapy in patients co-infected with chronic hepatitis C virus infection and HIV

scientific article

IP-10 predicts viral response and therapeutic outcome in difficult-to-treat patients with HCV genotype 1 infection

scientific article

Immune response in blood and tumour tissue in patients with metastatic malignant melanoma treated with IL-2, IFN alpha and histamine dihydrochloride.

scientific article published in January 2003

Immunotherapy with HDC/IL-2 may be clinically efficacious in acute myeloid leukemia of normal karyotype

scientific article published on 24 July 2019

Immunotherapy with histamine dihydrochloride and low-dose interleukin-2 favors sustained lymphocyte recovery in acute myeloid leukemia

scientific article published on 21 November 2014

Impact of killer-immunoglobulin-like receptor and human leukocyte antigen genotypes on the efficacy of immunotherapy in acute myeloid leukemia

scientific article published on 22 May 2017

Impact of obesity on the bioavailability of peginterferon-α2a and ribavirin and treatment outcome for chronic hepatitis C genotype 2 or 3

scientific article (publication date: 2012)

Impact of soluble CD26 on treatment outcome and hepatitis C virus-specific T cells in chronic hepatitis C virus genotype 1 infection

scientific article

Impaired production of alpha and gamma interferon in asymptomatic homosexual males

scientific article

Improved leukemia-free survival after postconsolidation immunotherapy with histamine dihydrochloride and interleukin-2 in acute myeloid leukemia: results of a randomized phase 3 trial

scientific article

Induction of apoptosis in NK cells by monocyte-derived reactive oxygen metabolites

scientific article published on 01 January 1996

Inosine Triphosphate Pyrophosphatase Dephosphorylates Ribavirin Triphosphate and Reduced Enzymatic Activity Potentiates Mutagenesis in Hepatitis C Virus

scientific article published on 12 September 2018

Interferon (IFN)-gamma-inducible protein-10: association with histological results, viral kinetics, and outcome during treatment with pegylated IFN-alpha 2a and ribavirin for chronic hepatitis C virus infection

scientific article

Interleukin 28B gene variation at rs12979860 determines early viral kinetics during treatment in patients carrying genotypes 2 or 3 of hepatitis C virus

scientific article published in June 2011

Interleukin-2 and histamine dihydrochloride in metastatic melanoma.

scientific article published in August 2002

Leukemia-free survival as a surrogate end point for overall survival in the evaluation of maintenance therapy for patients with acute myeloid leukemia in complete remission.

scientific article published on 5 May 2011

Leukocyte myeloperoxidase and pathogenesis of the post-polio syndrome

scientific article published in 2010

Leukocyte oxygen radical production determines disease severity in the recurrent Guillain-Barré syndrome

scientific article published on 8 August 2010

Locomotor activity and catecholamine receptor binding in adult normotensive and spontaneously hypertensive rats

scientific article published on 01 January 1980

Melanoma immunotherapy: a battle against radicals?

scientific article published on 01 May 2003

Monocyte-induced down-modulation of CD16 and CD56 antigens on human natural killer cells and its regulation by histamine H2-receptors

scientific article published on 01 November 1991

Monocyte-mediated suppression of IL-2-induced NK-cell activation. Regulation by 5-HT1A-type serotonin receptors

scientific article published on 01 August 1990

Monocytic AML cells inactivate antileukemic lymphocytes: role of NADPH oxidase/gp91(phox) expression and the PARP-1/PAR pathway of apoptosis

scientific article published on May 2012

NK cell expression of natural cytotoxicity receptors may determine relapse risk in older AML patients undergoing immunotherapy for remission maintenance.

scientific article published on 30 October 2015

NK cell-mediated killing of AML blasts: role of histamine, monocytes and reactive oxygen metabolites

scientific article published on 01 October 1996

NOX2 inhibition reduces oxidative stress and prolongs survival in murine KRAS-induced myeloproliferative disease

article

NOX2-dependent immunosuppression in chronic myelomonocytic leukemia.

scientific article published on 14 March 2017

Naloxone reverses reserpine-induced hypokinesia in rats

scientific article published on 01 September 1981

Natural immunity and chronic exercise in rats. The involvement of the spleen and the splenic nerves

scientific article published on 01 January 1996

Natural killer cell dysfunction and apoptosis induced by chronic myelogenous leukemia cells: role of reactive oxygen species and regulation by histamine

scientific article published on 01 September 2000

Nonresponder patients with hepatitis C virus genotype 2/3 infection: a question of low systemic interferon concentrations?

scientific article published in February 2010

Oxygen radical production and severity of the Guillain--Barré syndrome

scientific article published on 22 October 2007

Oxygen radical production in leukocytes and disease severity in multiple sclerosis.

scientific article published on 8 July 2009

Oxygen radicals induce poly(ADP-ribose) polymerase-dependent cell death in cytotoxic lymphocytes

scientific article published on 01 June 2006

PNPLA 3I148M genetic variant associates with insulin resistance and baseline viral load in HCV genotype 2 but not in genotype 3 infection

scientific article published on September 14, 2012

Phosphorotioated oligonucleotides trigger synthesis of human coagulation serine proteases.

scientific article published in November 2002

Predicting treatment outcome following 24 weeks peginterferon alpha-2a/ribavirin therapy in patients infected with HCV genotype 1: utility of HCV-RNA at day 0, day 22, day 29, and week 6.

scientific article published in January 2007

Randomized comparison of 12 or 24 weeks of peginterferon alpha-2a and ribavirin in chronic hepatitis C virus genotype 2/3 infection

scientific article

Reactive oxygen species induced by therapeutic CD20 antibodies inhibit natural killer cell-mediated antibody-dependent cellular cytotoxicity against primary CLL cells.

scientific article published on 16 April 2016

Redox remodeling by dendritic cells protects antigen-specific T cells against oxidative stress.

scientific article

Remission maintenance in acute myeloid leukemia: impact of functional histamine H2 receptors expressed by leukemic cells.

scientific article published on 11 June 2012

Remission maintenance therapy with histamine and interleukin-2 in acute myelogenous leukaemia

scientific article published on 01 March 1996

Reply: To PMID 24519039.

scientific article published on 24 September 2014

Response Prediction and Treatment Tailoring for Chronic Hepatitis C Virus Genotype 1 Infection

scientific article

Response prediction in chronic hepatitis C by assessment of IP-10 and IL28B-related single nucleotide polymorphisms

scientific article

Results of a multicenter randomized study to evaluate the safety and efficacy of combined immunotherapy with interleukin-2, interferon-{alpha}2b and histamine dihydrochloride versus dacarbazine in patients with stage IV melanoma

scientific article published on 20 August 2007

Retreatment with peg-interferon and ribavirin in patients with chronic hepatitis C virus genotype 2 or 3 infection with prior relapse

scientific article published on July 2013

Role of NOX2 for leukaemic expansion in a murine model of BCR-ABL1(+) leukaemia.

scientific article

Role of NOX2-Derived Reactive Oxygen Species in NK Cell-Mediated Control of Murine Melanoma Metastasis

scientific article published on 31 July 2017

Role of histamine in natural killer cell-dependent protection against herpes simplex virus type 2 infection in mice

scientific article published on May 1, 1995

Role of histamine in natural killer cell-mediated resistance against tumor cells.

scientific article published in December 1990

Role of natural killer cell subsets and natural cytotoxicity receptors for the outcome of immunotherapy in acute myeloid leukemia

scientific article published on 5 May 2015

Role of regulatory T cells in acute myeloid leukemia patients undergoing relapse-preventive immunotherapy

scientific article published on 18 July 2017

Role of serotonin in the regulation of human natural killer cell cytotoxicity

scientific article published on 01 August 1987

Role of serotonin in the regulation of interferon-gamma production by human natural killer cells

scientific article published on 01 February 1993

Role of the ERK pathway for oxidant-induced parthanatos in human lymphocytes.

scientific article

Serotonergic 5-HT1A receptors regulate a cell contact-mediated interaction between natural killer cells and monocytes

scientific article published on 01 January 1993

Serotonin protects NK cells against oxidatively induced functional inhibition and apoptosis.

scientific article published in July 2001

Synergistic activation of human natural killer cell cytotoxicity by histamine and interleukin-2

scientific article published on 01 January 1990

TLR-Stimulated Neutrophils Instruct NK Cells To Trigger Dendritic Cell Maturation and Promote Adaptive T Cell Responses.

scientific article

The CD16-/CD56bright subset of NK cells is resistant to oxidant-induced cell death

scientific article published on 01 July 2007

The HLA-B -21 dimorphism impacts on NK cell education and clinical outcome of immunotherapy in acute myeloid leukemia

scientific article published on 15 January 2019

The recurrent Guillain-Barré syndrome: a long-term population-based study

The response of Dunning R3327 prostatic adenocarcinoma to IL-2, histamine and radiation

scientific article published on April 1, 1998

The role of reactive oxygen metabolites in the transcriptional regulation of IFN-gamma gene expression by histamine in NK cells following IL-2 stimulation

scientific article published on 01 September 1996

Tumor suppressive action of indomethacin is NK-cell-independent

scientific article published on 01 September 1997

Validation of the internal reference technique for microdialysis measurements of interstitial histamine in the rat

scientific article published on 01 January 1999

Variants of the inosine triphosphate pyrophosphatase gene are associated with reduced relapse risk following treatment for HCV genotype 2/3.

scientific article

Voluntary chronic exercise augments in vivo natural immunity in rats

scientific article published on 01 May 1996

Weight-adjusted dosing of ribavirin and importance of hepatitis C virus RNA below 1000 IU/mL by day 7 in short-term peginterferon therapy for chronic genotype 2/3 hepatitis C virus infection

scientific article published on August 2008

Wider indications for treatment of chronic hepatitis B?

scientific article published on 17 December 2007

[Annus horribilis for MFR. The junior program is a lottery involving millions]

scientific article published on 01 April 1993