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List of works by Volker Vallon

7-D-ALA-Angiotensin 1-7 Blocks Renal Actions of Angiotensin 1-7 in the Anesthetized Rat ⬇️

scientific article published on July 1, 1998

A computational model for simulating solute transport and oxygen consumption along the nephrons

scientific article published on 5 October 2016

A role for the organic anion transporter OAT3 in renal creatinine secretion in mice.

scientific article

A special issue on glucose transporters in health and disease

scientific article published on 11 August 2020

Acute renal response to the non-peptide vasopressin V2-receptor antagonist SR 121463B in anesthetized rats

scientific article published on 01 September 2000

Acute saline expansion increases nephron filtration and distal flow rate but maintains tubuloglomerular feedback responsiveness: role of adenosine A1 receptors ⬇️

scientific article published on May 23, 2012

Adaptive changes in GFR, tubular morphology, and transport in subtotal nephrectomized kidneys: modeling and analysis.

scientific article published on 22 March 2017

Adenosine A(1) receptors determine glomerular hyperfiltration and the salt paradox in early streptozotocin diabetes mellitus

scientific article published on 10 March 2009

Adenosine and kidney function.

scientific article published on July 2006

Adenosine and tubuloglomerular feedback.

scientific article published on January 1997

Adenosine formed by 5'-nucleotidase mediates tubuloglomerular feedback.

scientific article published in July 2000

Adenosine receptors and the kidney

scientific article

Altered renal distal tubule structure and renal Na(+) and Ca(2+) handling in a mouse model for Gitelman's syndrome.

scientific article published in September 2004

Anomalous role for dietary salt in diabetes mellitus? ⬇️

scientific article published on May 31, 2011

Blunted DOCA/high salt induced albuminuria and renal tubulointerstitial damage in gene-targeted mice lacking SGK1

scientific article published on 10 August 2006

Blunted hypertensive effect of combined fructose and high-salt diet in gene-targeted mice lacking functional serum- and glucocorticoid-inducible kinase SGK1.

scientific article

Cardiac-specific overexpression of caveolin-3 attenuates cardiac hypertrophy and increases natriuretic peptide expression and signaling

scientific article

Cardiovascular benefits of SGLT2 inhibition in diabetes and chronic kidney diseases

scientific article published on 8 February 2018

Combined effects of carbonic anhydrase inhibitor and adenosine A1 receptor antagonist on hemodynamic and tubular function in the kidney.

scientific article

DOCA-induced phosphorylation of glycogen synthase kinase 3beta.

scientific article published on 14 March 2006

Decreased renal organic anion secretion and plasma accumulation of endogenous organic anions in OAT1 knock-out mice.

scientific article

Development of SGLT1 and SGLT2 inhibitors

article

Diabetes mellitus: Cardiovascular and renal benefits of SGLT2 inhibition: insights from CANVAS.

scientific article published on 7 August 2017

Dietary Na+ inhibits the open probability of the epithelial sodium channel in the kidney by enhancing apical P2Y2-receptor tone.

scientific article

Dipeptidyl peptidase IV inhibitor lowers PPARγ agonist-induced body weight gain by affecting food intake, fat mass, and beige/brown fat but not fluid retention

scientific article

Dipyridamole prevents diabetes-induced alterations of kidney function in rats

scientific article published on 01 February 1994

Disprocynium24 induces a dopamine-independent, eukaliuric diuresis and natriuresis in the anaesthetized rat

scientific article published on 01 December 1997

Do tubular changes in the diabetic kidney affect the susceptibility to acute kidney injury?

scientific article published on 24 September 2014

Dopamine D3 receptors in the rat kidney: glomerular and tubular actions

scientific article published on 01 January 1999

Effect of chronic salt loading on kidney function in early and established diabetes mellitus in rats

scientific article published on 01 July 1997

Effect of intratubular application of angiotensin 1-7 on nephron function

scientific article published on 01 January 1997

Effect of renal tubule-specific knockdown of the Na+/H+ exchanger NHE3 in Akita diabetic mice

scientific article published on 05 June 2019

Effects of NKCC2 isoform regulation on NaCl transport in thick ascending limb and macula densa: a modeling study

scientific article

Emotional instability but intact spatial cognition in adenosine receptor 1 knock out mice ⬇️

scientific article published on October 17, 2003

Estrogen Regulation of Duodenal Bicarbonate Secretion and Sex-Specific Protection of Human Duodenum ⬇️

scientific article published on May 27, 2011

Eukaliuric natriuresis and diuresis in response to disprocynium24: studies on the tubular site of action

scientific article published on 01 August 1998

Evidence for a role of protein kinase C-alpha in urine concentration.

scientific article published on 23 March 2004

Expression and insights on function of potassium channel TWIK-1 in mouse kidney

scientific article published on 16 July 2005

Expression and phosphorylation of the Na+-Cl- cotransporter NCC in vivo is regulated by dietary salt, potassium, and SGK1.

scientific article published on July 2009

Expression of Na+-D-glucose cotransporter SGLT2 in rodents is kidney-specific and exhibits sex and species differences.

scientific article published on 18 January 2012

Gene deletion of the Na+-glucose cotransporter SGLT1 ameliorates kidney recovery in a murine model of acute kidney injury induced by ischemia-reperfusion

scientific article published on 17 April 2019

Glomerular hyperfiltration and the salt paradox in early [corrected] type 1 diabetes mellitus: a tubulo-centric view.

scientific article

Glucose transporters in the kidney in health and disease

scientific article published on 06 March 2020

How Do Kidneys Adapt to a Deficit or Loss in Nephron Number?

scientific article published on 01 May 2019

Human C-peptide acutely lowers glomerular hyperfiltration and proteinuria in diabetic rats: a dose-response study.

scientific article published on 14 November 2001

Immunolocalization of protein kinase C isoenzymes alpha, beta I, beta II, delta, and epsilon in mouse kidney.

scientific article

Impaired regulation of renal K+ elimination in the sgk1-knockout mouse.

scientific article published in April 2004

In vivo studies of the genetically modified mouse kidney

scientific article published on 01 January 2003

Increase in SGLT1-mediated transport explains renal glucose reabsorption during genetic and pharmacological SGLT2 inhibition in euglycemia.

scientific article

Intestinal regulation of urinary sodium excretion and the pathophysiology of diabetic kidney disease: a focus on glucagon-like peptide 1 and dipeptidyl peptidase 4.

scientific article published on August 2014

Intratubular application of sodium azide inhibits loop of Henle reabsorption and tubuloglomerular feedback response in anesthetized rats ⬇️

scientific article published on September 1, 1998

Intrinsic control of sodium excretion in the distal nephron by inhibitory purinergic regulation of the epithelial Na(+) channel.

scientific article published on January 2012

KCNQ1-dependent transport in renal and gastrointestinal epithelia

scientific journal article

Ketosis and diabetic ketoacidosis in response to SGLT2 inhibitors: Basic mechanisms and therapeutic perspectives.

scientific article published on 18 January 2017

Kidney function in mice: thiobutabarbital versus alpha-chloralose anesthesia.

scientific article published on 30 September 2004

Knockout of Na+-glucose cotransporter SGLT1 mitigates diabetes-induced upregulation of nitric oxide synthase NOS1 in the macula densa and glomerular hyperfiltration

scientific article published on 15 May 2019

Knockout of Na-glucose transporter SGLT2 attenuates hyperglycemia and glomerular hyperfiltration but not kidney growth or injury in diabetes mellitus

scientific article published on 14 November 2012

Lack of effect of extracellular adenosine generation and signaling on renal erythropoietin secretion during hypoxia

scientific article published on 12 September 2007

Lessons from mouse mutants of epithelial sodium channel and its regulatory proteins.

scientific article

Macula Densa SGLT1-NOS1-Tubuloglomerular Feedback Pathway, a New Mechanism for Glomerular Hyperfiltration during Hyperglycemia

scientific article published on 13 March 2019

Mice lacking P2Y2 receptors have salt-resistant hypertension and facilitated renal Na+ and water reabsorption.

scientific article published on 15 June 2007

Mice lacking protein kinase C beta present modest increases in systolic blood pressure and NH4Cl-induced metabolic acidosis.

scientific article

Micropuncturing the nephron.

scientific article

Mineralocorticoid-induced sodium appetite and renal salt retention: evidence for common signaling and effector mechanisms

scientific article

Modeling oxygen consumption in the proximal tubule: effects of NHE and SGLT2 inhibition

scientific article published on 8 April 2015

Molecular determinants of renal glucose reabsorption. Focus on “Glucose transport by human renal Na+/d-glucose cotransporters SGLT1 and SGLT2” ⬇️

scientific article published on November 3, 2010

Molecular mechanisms of calcium-sensing receptor-mediated calcium signaling in the modulation of epithelial ion transport and bicarbonate secretion

scientific article

Na(+)-D-glucose cotransporter SGLT1 is pivotal for intestinal glucose absorption and glucose-dependent incretin secretion

scientific article published on 28 November 2011

New insights into the role of serum- and glucocorticoid-inducible kinase SGK1 in the regulation of renal function and blood pressure.

scientific article

Once daily administration of the SGLT2 inhibitor, empagliflozin, attenuates markers of renal fibrosis without improving albuminuria in diabetic db/db mice

scientific article published on 26 May 2016

Ornithine decarboxylase inhibitor eliminates hyperresponsiveness of the early diabetic proximal tubule to dietary salt

scientific article published on 18 June 2008

Overlapping in vitro and in vivo specificities of the organic anion transporters OAT1 and OAT3 for loop and thiazide diuretics.

scientific article published on 23 January 2008

P2 receptors in the regulation of renal transport mechanisms.

scientific article published on 31 October 2007

P2Y receptors and kidney function.

scientific article

P2Y2 receptor activation inhibits the expression of the sodium-chloride cotransporter NCC in distal convoluted tubule cells.

scientific article published on 25 January 2014

PPARγ agonist-induced fluid retention depends on αENaC expression in connecting tubules

scientific article published on 19 December 2014

Paracrine regulation of the epithelial Na+ channel in the mammalian collecting duct by purinergic P2Y2 receptor tone

scientific article

Pathophysiology of the diabetic kidney.

scientific article published on July 2011

Peroxisome proliferator-activated receptor-γ agonists repress epithelial sodium channel expression in the kidney.

scientific article

Potassium diet as a determinant for the renal response to systemic potassium channel modulation in anesthetized rats

scientific article published on 01 August 1998

Predicted consequences of diabetes and SGLT inhibition on transport and oxygen consumption along a rat nephron.

scientific article published on 13 January 2016

Primary proximal tubule hyperreabsorption and impaired tubular transport counterregulation determine glomerular hyperfiltration in diabetes: a modeling analysis

scientific article published on February 2017

Probing SGLT2 as a therapeutic target for diabetes: basic physiology and consequences.

scientific article

Reduced renal calcium excretion in the absence of sclerostin expression: evidence for a novel calcium-regulating bone kidney axis.

scientific article

Regulation of KCNE1-dependent K(+) current by the serum and glucocorticoid-inducible kinase (SGK) isoforms

scientific article (publication date: February 2003)

Regulation of renal NaCl and water transport by the ATP/UTP/P2Y2 receptor system

scientific article

Regulation of the Na+-Cl- cotransporter by dietary NaCl: a role for WNKs, SPAK, OSR1, and aldosterone

scientific article

Renal Ca2+ wasting, hyperabsorption, and reduced bone thickness in mice lacking TRPV5

scientific article

Renal Effects of Incretin-Based Diabetes Therapies: Pre-clinical Predictions and Clinical Trial Outcomes.

scientific article published on 13 April 2018

Renal potassium handling in rats with subtotal nephrectomy: Modeling and Analysis.

scientific article published on 13 December 2017

Renal tubular solute transport and oxygen consumption: insights from computational models

scientific article published on 01 September 2018

Resistance of mice lacking the serum- and glucocorticoid-inducible kinase SGK1 against salt-sensitive hypertension induced by a high-fat diet

scientific article published on 26 September 2006

Role of Sgk1 in salt and potassium homeostasis.

scientific article

Role of adenosine in tubuloglomerular feedback and acute renal failure.

scientific article published on December 1996

SGK1-dependent ENaC processing and trafficking in mice with high dietary K intake and elevated aldosterone

scientific article published on 13 July 2016

SGK1-dependent cardiac CTGF formation and fibrosis following DOCA treatment.

scientific article

SGK1-sensitive renal tubular glucose reabsorption in diabetes.

scientific article published on 21 January 2009

SGLT2 Inhibition in a Kidney with Reduced Nephron Number: Modeling and Analysis of Solute Transport and Metabolism.

scientific article published on 17 January 2018

SGLT2 inhibition and kidney protection

scientific article published on 28 June 2018

SGLT2 inhibition and renal urate excretion: role of luminal glucose, GLUT9, and URAT1

scientific article published on 14 November 2018

SGLT2 inhibitor empagliflozin reduces renal growth and albuminuria in proportion to hyperglycemia and prevents glomerular hyperfiltration in diabetic Akita mice.

scientific article

SGLT2 mediates glucose reabsorption in the early proximal tubule.

scientific article

Salt-sensitivity of proximal reabsorption alters macula densa salt and explains the paradoxical effect of dietary salt on glomerular filtration rate in diabetes mellitus.

scientific article published in July 2002

Serum- and glucocorticoid-inducible kinase 1 in the regulation of renal and extrarenal potassium transport ⬇️

scientific article published on November 1, 2011

Sodium glucose cotransporter 2 inhibition in the diabetic kidney: an update

scientific article

Sodium glucose cotransporter SGLT1 as a therapeutic target in diabetes mellitus.

scientific article published on 21 March 2016

Sodium reabsorption in thick ascending limb of Henle's loop: effect of potassium channel blockade in vivo.

scientific article published in July 2000

Sodium-glucose transport: role in diabetes mellitus and potential clinical implications.

scientific article published on September 2010

Solute transport and oxygen consumption along the nephrons: effects of Na+ transport inhibitors

scientific article

Targeting renal glucose reabsorption to treat hyperglycaemia: the pleiotropic effects of SGLT2 inhibition.

scientific article published on 22 November 2016

The Potential Role of SGLT2 Inhibitors in the Treatment of Type 1 Diabetes Mellitus.

scientific article published on 16 April 2018

The mechanisms and therapeutic potential of SGLT2 inhibitors in diabetes mellitus.

scientific article

The organic anion transporter OAT3 enhances the glucosuric effect of the SGLT2 inhibitor empagliflozin

scientific article published on 7 February 2018

The physiological impact of the serum and glucocorticoid-inducible kinase SGK1

scientific article

The salt paradox of the early diabetic kidney is independent of renal innervation.

scientific article published in January 2003

The tubular hypothesis of nephron filtration and diabetic kidney disease

scientific article published on 09 March 2020

Thiazolidinedione-induced fluid retention is independent of collecting duct alphaENaC activity.

scientific article published on 21 January 2009

Transport regulation by the serum- and glucocorticoid-inducible kinase SGK1

scientific article published on 01 February 2005

Tribbles homolog 3 attenuates mammalian target of rapamycin complex-2 signaling and inflammation in the diabetic kidney

scientific article

Tubular Recovery after Acute Kidney Injury.

scientific article

Tubular Transport in Acute Kidney Injury: Relevance for Diagnosis, Prognosis and Intervention.

scientific article

Tubuloglomerular feedback in the kidney: insights from gene-targeted mice.

scientific article

Tubuloglomerular feedback responses of the downstream efferent resistance: unmasking a role for adenosine?

scientific article

Unmasking a sustained negative effect of SGLT2 inhibition on body fluid volume in the rat

scientific article published on 23 May 2018

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