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List of works by Anthony R Fehr

Bacterial Artificial Chromosome-Based Lambda Red Recombination with the I-SceI Homing Endonuclease for Genetic Alteration of MERS-CoV

scientific article published on 01 January 2020

Coronavirus and PARP expression dysregulate the NAD Metabolome: a potentially actionable component of innate immunity

scientific article published on 19 April 2020

Coronaviruses: an overview of their replication and pathogenesis.

scientific article

Cyclin A degradation by primate cytomegalovirus protein pUL21a counters its innate restriction of virus replication

scientific article

Dysregulated Type I Interferon and Inflammatory Monocyte-Macrophage Responses Cause Lethal Pneumonia in SARS-CoV-Infected Mice.

scientific article published on February 2016

Human Cytomegalovirus Early Protein pUL21a Promotes Efficient Viral DNA Synthesis and the Late Accumulation of Immediate-Early Transcripts ⬇️

scientific article published on November 3, 2010

Human cytomegalovirus gene UL21a encodes a short-lived cytoplasmic protein and facilitates virus replication in fibroblasts

scientific article

Human cytomegalovirus infection of langerhans-type dendritic cells does not require the presence of the gH/gL/UL128-131A complex and is blocked after nuclear deposition of viral genomes in immature cells

scientific article published on 23 October 2013

IFN-I response timing relative to virus replication determines MERS coronavirus infection outcomes

scientific article published on 29 July 2019

In Situ Tagged nsp15 Reveals Interactions with Coronavirus Replication/Transcription Complex-Associated Proteins.

scientific article published on 31 January 2017

In vitro and in vivo characterization of the Pseudomonas aeruginosa cyclic AMP (cAMP) phosphodiesterase CpdA, required for cAMP homeostasis and virulence factor regulation.

scientific article

MERS-CoV 4b protein interferes with the NF-κB-dependent innate immune response during infection.

scientific article published on 25 January 2018

MERS-CoV endoribonuclease and accessory proteins jointly evade host innate immunity during infection of lung and nasal epithelial cells

scientific article published in 2022

Middle East Respiratory Syndrome: Emergence of a Pathogenic Human Coronavirus

scientific article published on 26 August 2016

Murine Coronavirus Infection Activates the Aryl Hydrocarbon Receptor in an Indoleamine 2,3-Dioxygenase-Independent Manner, Contributing to Cytokine Modulation and Proviral TCDD-Inducible-PARP Expression

scientific article published on 17 January 2020

Murine cytomegalovirus protein pM79 is a key regulator for viral late transcription

scientific article published on 12 June 2013

Proteasome-Dependent Disruption of the E3 Ubiquitin Ligase Anaphase-Promoting Complex by HCMV Protein pUL21a ⬇️

scientific article published on July 5, 2012

Proteolytic processing of Middle East respiratory syndrome coronavirus spikes expands virus tropism

scientific article published on 10 October 2016

Selective Packaging in Murine Coronavirus Promotes Virulence by Limiting Type I Interferon Responses.

scientific article published in May 2018

Structure-guided design of potent and permeable inhibitors of MERS coronavirus 3CL protease that utilize a piperidine moiety as a novel design element

scientific article published on 6 March 2018

The Conserved Coronavirus Macrodomain Promotes Virulence and Suppresses the Innate Immune Response during Severe Acute Respiratory Syndrome Coronavirus Infection

scientific article published on 13 December 2016

The SARS-CoV-2 conserved macrodomain is a highly efficient ADP-ribosylhydrolase enzyme

scientific article published on 13 May 2020

The SARS-CoV-2 conserved macrodomain is a mono-ADP-ribosylhydrolase

scientific article published on 06 November 2020

The Viral Macrodomain Counters Host Antiviral ADP-Ribosylation

scientific article published on 31 March 2020

The coronavirus macrodomain is required to prevent PARP-mediated inhibition of virus replication and enhancement of IFN expression.

scientific article published on 16 May 2019

The coronavirus nucleocapsid protein is ADP-ribosylated.

scientific article

The human cytomegalovirus gene UL79 is required for the accumulation of late viral transcripts.

scientific article published on 2 March 2011

The nsp3 macrodomain promotes virulence in mice with coronavirus-induced encephalitis

scientific article

Viral Macrodomains: Unique Mediators of Viral Replication and Pathogenesis.

scientific article published on 18 December 2017

Virus-induced inflammasome activation is suppressed by prostaglandin D2/DP1 signaling.

scientific article published on 19 June 2017

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