List of works - Amy Ramsey

A novel allosteric modulator of the cannabinoid CB1 receptor ameliorates hyperdopaminergia endophenotypes in rodent models

scientific article published on 08 October 2020

Behavioral Effects of a Potential Novel TAAR1 Antagonist

scientific article published on 04 September 2018

Changes in dendritic spine density in the nucleus accumbens do not underlie ethanol sensitization

scientific article published on 4 September 2015

Connectivity Analyses of Bioenergetic Changes in Schizophrenia: Identification of Novel Treatments

scientific article published on 18 October 2018

Consequences of NMDA receptor deficiency can be rescued in the adult brain

scientific article published on 17 August 2020

D1 dopamine receptor coupling to PLCβ regulates forward locomotion in mice

scientific article

Defects in Bioenergetic Coupling in Schizophrenia.

scientific article published on 24 October 2017

Dexmedetomidine Prevents Excessive γ-Aminobutyric Acid Type A Receptor Function after Anesthesia

scientific article published on 01 September 2018

Diazepam improves aspects of social behaviour and neuron activation in NMDA receptor-deficient mice.

scientific article

Differential effects of NMDA receptor antagonism on spine density.

scientific article published on 6 October 2014

Dissecting the contribution of individual receptor subunits to the enhancement of N-methyl-d-aspartate currents by dopamine D1 receptor activation in striatum

scientific article published on 11 May 2011

Dynamic disorganization of synaptic NMDA receptors triggered by autoantibodies from psychotic patients.

scientific article published on 27 November 2017

Hyperdopaminergia and NMDA receptor hypofunction disrupt neural phase signaling

scientific article

Impaired NMDA receptor transmission alters striatal synapses and DISC1 protein in an age-dependent manner.

scientific article

Increased expression of the dopamine transporter leads to loss of dopamine neurons, oxidative stress and l-DOPA reversible motor deficits.

scientific article

Measurement of lactate levels in postmortem brain, iPSCs, and animal models of schizophrenia

scientific article published on 25 March 2019

MicroRNA-219 modulates NMDA receptor-mediated neurobehavioral dysfunction

scientific article

Misassembly of full-length Disrupted-in-Schizophrenia 1 protein is linked to altered dopamine homeostasis and behavioral deficits.

scientific article

N-aryl piperazine metabotropic glutamate receptor 5 positive allosteric modulators possess efficacy in preclinical models of NMDA hypofunction and cognitive enhancement.

scientific article

N-terminal tagging of the dopamine transporter impairs protein expression and trafficking in vivo.

scientific article published on 2 June 2014

NMDA receptor-deficient mice display sexual dimorphism in the onset and severity of behavioural abnormalities.

scientific article

NR1 knockdown mice as a representative model of the glutamate hypothesis of schizophrenia.

scientific article

Neuron-specific deficits of bioenergetic processes in the dorsolateral prefrontal cortex in schizophrenia.

scientific article published in March 2018

Pharmacological characterization of membrane-expressed human trace amine-associated receptor 1 (TAAR1) by a bioluminescence resonance energy transfer cAMP biosensor

scientific article

Postsynaptic Density-95 Isoform Abnormalities in Schizophrenia

scientific article published on 26 January 2017

Preparation of synaptic plasma membrane and postsynaptic density proteins using a discontinuous sucrose gradient

scientific article published on 3 September 2014

Progressive neuroanatomical changes caused by Grin1 loss-of-function mutation

scientific article published on 09 July 2019

Reduced D2-mediated signaling activity and trans-synaptic upregulation of D1 and D2 dopamine receptors in mice overexpressing the dopamine transporter.

scientific article published on 30 September 2008

Restoring striatal WAVE-1 improves maze exploration performance of GluN1 knockdown mice

scientific article published in PLoS ONE

Sustained N-methyl-d-aspartate receptor hypofunction remodels the dopamine system and impairs phasic signaling.

scientific article

Tricyclic and tetracyclic antidepressants upregulate VMAT2 activity and rescue disease-causing VMAT2 variants

scientific article published in October 2024

Tricyclic and tetracyclic antidepressants upregulate VMAT2 activity and rescue disease-causing VMAT2 variants

scientific article published on 19 October 2023

Vulnerability to omega-3 deprivation in a mouse model of NMDA receptor hypofunction

scientific article

α5GABAA receptor deficiency causes autism-like behaviors

scientific article published on 19 April 2016

List of works by Amy Ramsey

A novel allosteric modulator of the cannabinoid CB1 receptor ameliorates hyperdopaminergia endophenotypes in rodent models

Behavioral Effects of a Potential Novel TAAR1 Antagonist

Changes in dendritic spine density in the nucleus accumbens do not underlie ethanol sensitization

Connectivity Analyses of Bioenergetic Changes in Schizophrenia: Identification of Novel Treatments

Consequences of NMDA receptor deficiency can be rescued in the adult brain

D1 dopamine receptor coupling to PLCβ regulates forward locomotion in mice

Defects in Bioenergetic Coupling in Schizophrenia.

Dexmedetomidine Prevents Excessive γ-Aminobutyric Acid Type A Receptor Function after Anesthesia

Diazepam improves aspects of social behaviour and neuron activation in NMDA receptor-deficient mice.

Differential effects of NMDA receptor antagonism on spine density.

Dissecting the contribution of individual receptor subunits to the enhancement of N-methyl-d-aspartate currents by dopamine D1 receptor activation in striatum

Dynamic disorganization of synaptic NMDA receptors triggered by autoantibodies from psychotic patients.

Hyperdopaminergia and NMDA receptor hypofunction disrupt neural phase signaling

Impaired NMDA receptor transmission alters striatal synapses and DISC1 protein in an age-dependent manner.

Increased expression of the dopamine transporter leads to loss of dopamine neurons, oxidative stress and l-DOPA reversible motor deficits.

Measurement of lactate levels in postmortem brain, iPSCs, and animal models of schizophrenia

MicroRNA-219 modulates NMDA receptor-mediated neurobehavioral dysfunction

Misassembly of full-length Disrupted-in-Schizophrenia 1 protein is linked to altered dopamine homeostasis and behavioral deficits.

N-aryl piperazine metabotropic glutamate receptor 5 positive allosteric modulators possess efficacy in preclinical models of NMDA hypofunction and cognitive enhancement.

N-terminal tagging of the dopamine transporter impairs protein expression and trafficking in vivo.

NMDA receptor-deficient mice display sexual dimorphism in the onset and severity of behavioural abnormalities.

NR1 knockdown mice as a representative model of the glutamate hypothesis of schizophrenia.

Neuron-specific deficits of bioenergetic processes in the dorsolateral prefrontal cortex in schizophrenia.

Pharmacological characterization of membrane-expressed human trace amine-associated receptor 1 (TAAR1) by a bioluminescence resonance energy transfer cAMP biosensor

Postsynaptic Density-95 Isoform Abnormalities in Schizophrenia

Preparation of synaptic plasma membrane and postsynaptic density proteins using a discontinuous sucrose gradient

Progressive neuroanatomical changes caused by Grin1 loss-of-function mutation

Reduced D2-mediated signaling activity and trans-synaptic upregulation of D1 and D2 dopamine receptors in mice overexpressing the dopamine transporter.

Restoring striatal WAVE-1 improves maze exploration performance of GluN1 knockdown mice

Sustained N-methyl-d-aspartate receptor hypofunction remodels the dopamine system and impairs phasic signaling.

Tricyclic and tetracyclic antidepressants upregulate VMAT2 activity and rescue disease-causing VMAT2 variants

Tricyclic and tetracyclic antidepressants upregulate VMAT2 activity and rescue disease-causing VMAT2 variants

Vulnerability to omega-3 deprivation in a mouse model of NMDA receptor hypofunction

α5GABAA receptor deficiency causes autism-like behaviors