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List of works by Thomas G Forsthuber

A T cell epitope-based vaccine protects against chlamydial infection in HLA-DR4 transgenic mice.

scientific article

Adjuvant-guided type-1 and type-2 immunity: infectious/noninfectious dichotomy defines the class of response

scientific article published in April 1999

Aire is not essential for regulating neuroinflammatory disease in mice transgenic for human autoimmune-diseases associated MHC class II genes HLA-DR2b and HLA-DR4

article

Allergen-specific MHC class II tetramer+ cells are detectable in allergic, but not in nonallergic, individuals

scientific article published on 01 April 2006

Anti-CRLF2 Antibody-Armored Biodegradable Nanoparticles for Childhood B-ALL

scientific article published on April 2013

Antigen-specific CD4+ T cells produce sufficient IFN-gamma to mediate robust protective immunity against genital Chlamydia muridarum infection.

scientific article published on March 2008

Antivirus immune activity in multiple sclerosis correlates with MRI activity.

scientific article published on 4 May 2015

Autoreactive T cells promote post-traumatic healing in the central nervous system.

scientific article published on January 2003

Body fluid biomarkers in multiple sclerosis: how far we have come and how they could affect the clinic now and in the future

scientific article

Determinant spreading and the dynamics of the autoimmune T-cell repertoire.

scientific article

Developmentally regulated gene expression of Th2 cytokines in the brain.

scientific article published on July 2000

Differential expression of the HLA-B7 and the HLA-A2 gene in transfected mouse L(tk-) cells after stimulation by mouse interferon

scientific article published on 01 January 1987

Does the frequency and avidity spectrum of the neuroantigen-specific T cells in the blood mirror the autoimmune process in the central nervous system of mice undergoing experimental allergic encephalomyelitis?

scientific article published in April 2005

ELISPOT Techniques

scientific article published on 01 January 2016

ERK1-deficient mice show normal T cell effector function and are highly susceptible to experimental autoimmune encephalomyelitis.

scientific article published in August 2005

Early response index: a statistic to discover potential early stage disease biomarkers.

scientific article

Efficient presentation of myelin oligodendrocyte glycoprotein peptides but not protein by astrocytes from HLA-DR2 and HLA-DR4 transgenic mice

scientific article published on 04 January 2006

Emerging drugs for primary progressive multiple sclerosis

scientific article published on 11 April 2018

Expert Review of Clinical Immunology 10-year anniversary issue. Foreword

scientific article published in January 2015

Frequencies of neuroantigen-specific T cells in the central nervous system versus the immune periphery during the course of experimental allergic encephalomyelitis

scientific article published on 01 April 2001

Glucan-Chitin Particles Enhance Th17 Response and Improve Protective Efficacy of a Multivalent Antigen (rCpa1) against Pulmonary Coccidioides posadasii Infection

scientific article published on 25 October 2018

High immunogenicity of intracellular myelin oligodendrocyte glycoprotein epitopes.

scientific article

IFN-γ ameliorates autoimmune encephalomyelitis by limiting myelin lipid peroxidation.

scientific article

Identification of Iguratimod as an Inhibitor of Macrophage Migration Inhibitory Factor (MIF) with Steroid-sparing Potential

scientific article published on 28 October 2016

Identification of LFA-1 as a Candidate Autoantigen in Treatment-Resistant Lyme Arthritis ⬇️

scientific article published on July 31, 1998

Immunization with a combination of integral chlamydial antigens and a defined secreted protein induces robust immunity against genital chlamydial challenge.

scientific article

Immunoenrichment microwave and magnetic proteomics for quantifying CD47 in the experimental autoimmune encephalomyelitis model of multiple sclerosis.

scientific article published on December 2012

Immunological adjuvants efficiently induce antigen-specific T cell responses in old mice: implications for vaccine adjuvant development in aged individuals

scientific article published on 01 January 2002

In vivo blockade of macrophage migration inhibitory factor ameliorates acute experimental autoimmune encephalomyelitis by impairing the homing of encephalitogenic T cells to the central nervous system

scientific article published on 01 February 2003

Induction of polyclonal CD8+ T cell activation and effector function by Pertussis toxin.

scientific article

Is there a place for 'immuno' in the immunotherapy of multiple sclerosis?

scientific article published on May 2009

Kinetics of IL-17- and interferon-gamma-producing PLPp-specific CD4 T cells in EAE induced by coinjection of PLPp/IFA with pertussis toxin in SJL mice

scientific article published on 14 April 2010

M-Cells Contribute to the Entry of an Oral Vaccine but Are Not Essential for the Subsequent Induction of Protective Immunity against Francisella tularensis

scientific article

MACOP-B chemotherapy for the treatment of high grade and intermediate grade non Hodgkin's lymphoma

scientific article published on 01 January 1990

MOG transmembrane and cytoplasmic domains contain highly stimulatory T-cell epitopes in MS.

scientific article

Mast Cell TLR2 Signaling Is Crucial for Effective Killing of Francisella tularensis ⬇️

scientific article published on April 23, 2012

Mast cell/IL-4 control of Francisella tularensis replication and host cell death is associated with increased ATP production and phagosomal acidification

scientific article

Mast cells: multitalented facilitators of protection against bacterial pathogens ⬇️

scientific article published on February 1, 2013

Microwave & magnetic (M2) proteomics reveals CNS-specific protein expression waves that precede clinical symptoms of experimental autoimmune encephalomyelitis.

scientific article

Microwave and magnetic (M(2) ) proteomics of the experimental autoimmune encephalomyelitis animal model of multiple sclerosis

scientific article published on December 2012

More than just a T-box: the role of T-bet as a possible biomarker and therapeutic target in autoimmune diseases.

scientific article

Non-FcεR bearing mast cells secrete sufficient interleukin-4 to control Francisella tularensis replication within macrophages ⬇️

scientific article published on May 12, 2011

Pentraxin 3: an immune modulator of infection and useful marker for disease severity assessment in sepsis.

scientific article published on 16 March 2016

Prosurvival and proapoptotic functions of ERK1/2 activation in murine thymocytes in vitro.

scientific article

Quo vadis Th1 and Th2 cells in autoimmunity and infectious diseases: Th17 cells, the new kid on the block

scientific article published on 01 May 2007

Regulation of adaptive immunity by the fractalkine receptor during autoimmune inflammation

scientific article published on July 2013

Serum Neuroinflammatory Disease-Induced Central Nervous System Proteins Predict Clinical Onset of Experimental Autoimmune Encephalomyelitis.

scientific article published on 17 July 2017

Shifting T-cell activation thresholds in autoimmunity and determinant spreading

scientific article published on 01 August 1998

Small molecule inhibitor of antigen binding and presentation by HLA-DR2b as a therapeutic strategy for the treatment of multiple sclerosis.

scientific article published on 11 October 2013

Spreading of T-cell autoimmunity to cryptic determinants of an autoantigen

scientific article published on July 9, 1992

Stability of T-cell lineages in autoimmune diseases. ⬇️

scientific article published on May 2012

Suramin has adjuvant properties and promotes expansion of antigen-specific Th1 and Th2 cells in vivo.

scientific article published in January 2004

T cell epitopes of human myelin oligodendrocyte glycoprotein identified in HLA-DR4 (DRB1*0401) transgenic mice are encephalitogenic and are presented by human B cells

scientific article published on 01 December 2001

T cell subsets and their signature cytokines in autoimmune and inflammatory diseases

scientific article published on 30 October 2014

T-cell activation and receptor downmodulation precede deletion induced by mucosally administered antigen.

scientific article

Targeting "Retired Antigens" for Cancer Immunoprevention.

scientific article

Targeting "bad" B cells in multiple sclerosis: Could laquinimod be part of the armamentarium?

scientific article published on 21 September 2016

The PLPp-specific T-cell population promoted by pertussis toxin is characterized by high frequencies of IL-17-producing cells

scientific article published on 18 September 2007

The contribution of interleukin-12/interferon-gamma axis in protection against neonatal pulmonary Chlamydia muridarum challenge

scientific article

The cytokine signature of MOG-specific CD4 cells in the EAE of C57BL/6 mice.

scientific article published on 27 October 2005

The enhanced antigen-specific production of cytokines induced by pertussis toxin is due to clonal expansion of T cells and not to altered effector functions of long-term memory cells.

scientific article published in August 2000

The kinetics of myelin antigen uptake by myeloid cells in the central nervous system during experimental autoimmune encephalomyelitis

scientific article

Therapeutic enzyme deimmunization by combinatorial T-cell epitope removal using neutral drift

scientific article

Trends in HLA antibody screening and identification and their role in transplantation.

scientific article published on May 2008

Tumor necrosis factor alpha production from CD8+ T cells mediates oviduct pathological sequelae following primary genital Chlamydia muridarum infection

scientific article

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