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List of works by David J Curtis

A 9-gene score for risk stratification in B-cell acute lymphoblastic leukemia

scientific article published on 02 June 2020

A critical role for the transcription factor Scl in platelet production during stress thrombopoiesis

scientific article

A mouse model of hereditary coproporphyria identified in an ENU mutagenesis screen

scientific article published on 9 June 2017

A novel role for Lyl1 in primitive erythropoiesis

scientific article published on 11 October 2018

Aberrant mast-cell differentiation in mice lacking the stem-cell leukemia gene

scientific journal article

Activation of the erythroid K-Cl cotransporter Kcc1 enhances sickle cell disease pathology in a humanized mouse model.

scientific article published on 8 October 2015

Acute myeloid leukaemia relapsing after allogeneic haematopoietic stem cell transplantation: prognostic factors and impact of initial therapy of relapse.

scientific article published on 19 June 2017

Adaptor protein SKAP55R is associated with myeloid differentiation and growth arrest

scientific article (publication date: November 2000)

Adverse impact of high donor CD3+ cell dose on outcome following tandem auto-NMA allogeneic transplantation for high-risk myeloma.

scientific article published on 20 March 2017

An ENU-induced mouse mutant of SHIP1 reveals a critical role of the stem cell isoform for suppression of macrophage activation.

scientific article

Bone marrow cells play only a very minor role in chronic liver regeneration induced by a choline-deficient, ethionine-supplemented diet.

scientific article published on 3 June 2008

Bone marrow transplantation corrects haemolytic anaemia in a novel ENU mutagenesis mouse model of TPI deficiency.

scientific article

Characterization of -mutant mice with microcytic phenotypes

scientific article published on 01 August 2018

Comparison of biosimilar filgrastim with originator filgrastim for peripheral blood stem cell mobilization and engraftment in patients with multiple myeloma undergoing autologous stem cell transplantation.

scientific article published on 14 July 2015

Concise review: Blood relatives: formation and regulation of hematopoietic stem cells by the basic helix-loop-helix transcription factors stem cell leukemia and lymphoblastic leukemia-derived sequence 1.

scientific article published on June 2012

Contemporary analysis of functional immune recovery to opportunistic and vaccine-preventable infections after allogeneic haemopoietic stem cell transplantation

scientific article published on 05 October 2018

Cyclosporin, methotrexate and prednisolone for graft-versus-host disease prophylaxis in allogeneic peripheral blood progenitor cell transplants.

scientific article published on 7 January 2008

ENU mutagenesis identifies the first mouse mutants reproducing human β-thalassemia at the genomic level

scientific article published on 2 October 2012

Fludarabine-related autoimmune haemolytic anaemia in patients with chronic lymphocytic leukaemia

scientific article published on 01 October 1995

Functional but abnormal adult erythropoiesis in the absence of the stem cell leukemia gene

scientific article published on August 2005

Genetic heterogeneity of granulocytes for the JAK2 V617F mutation in essential thrombocythaemia: implications for mutation detection in peripheral blood

scientific article published on 01 August 2006

Granulocyte colony-stimulating factor and stem cell factor improve endogenous repair after myocardial infarction

scientific article published on 23 February 2006

Hmgb3: an HMG-box family member expressed in primitive hematopoietic cells that inhibits myeloid and B-cell differentiation ⬇️

scientific article published on April 24, 2003

Important factors in implementation of lineage-specific chimerism analysis for routine use

scientific article published on 21 October 2020

Inhibition of apoptosis by BCL2 prevents leukemic transformation of a murine myelodysplastic syndrome

scientific article

LIM-domain-only proteins in cancer.

scientific article published on 10 January 2013

Leptin-deficient obesity prolongs survival in a murine model of myelodysplastic syndrome.

scientific article published on 25 January 2018

Leukemic cells from murine myeloid leukemia display an intrinsic ability for autonomous proliferation

scientific article published on 01 January 2000

Loss of Dynamin 2 GTPase function results in microcytic anaemia

scientific article published on 3 May 2017

Loss-of-function mutations of Dynamin 2 promote T-ALL by enhancing IL-7 signalling.

scientific article published on 27 April 2016

Monosomal karyotype predicts inferior survival independently of a complex karyotype in patients with myelodysplastic syndromes

scientific article published on 4 June 2015

NF-Y regulates LIF-induced transcription of the signaling adaptor SKAP55R in myeloid cells ⬇️

scientific article published on December 1, 2001

Novel roles for erythroid Ankyrin-1 revealed through an ENU-induced null mouse mutant

scientific article published on 28 January 2009

Oncogenic ZEB2 activation drives sensitivity toward KDM1A inhibition in T-cell acute lymphoblastic leukemia

scientific article published on 9 January 2017

PRMT5-mediated methylation of histone H4R3 recruits DNMT3A, coupling histone and DNA methylation in gene silencing.

scientific article published on 22 February 2009

PUMA promotes apoptosis of hematopoietic progenitors driving leukemic progression in a mouse model of myelodysplasia

scientific article published on 08 January 2016

Parvovirus B19 in HIV infection: a treatable cause of anemia.

scientific article published on August 1996

Perturbed thymopoiesis in vitro in the absence of suppressor of cytokine signalling 1 and 3.

scientific article

Requirement for Lyl1 in a model of Lmo2-driven early T-cell precursor ALL.

scientific article published on 7 August 2013

Restricted cell cycle is essential for clonal evolution and therapeutic resistance of pre-leukemic stem cells

scientific article published in Nature Communications

SCL is required for normal function of short-term repopulating hematopoietic stem cells

scientific journal article

SCL/Tal1 and lymphoid versus myeloid lineage assignment

scientific article published on 01 February 2005

Safe and effective use of outpatient non-myeloablative allogeneic stem cell transplantation for myeloma

scientific article published on 9 May 2014

Shared roles for Scl and Lyl1 in murine platelet production and function

scientific article published on 12 July 2019

Small molecule inhibition of Dynamin-dependent endocytosis targets multiple niche signals and impairs leukemia stem cells

scientific article published on 04 December 2020

Specification of neurotransmitter identity by Tal1 in thalamic nuclei.

scientific article published on 7 July 2017

Targeted therapies for T-cell acute lymphoblastic leukaemia (T-ALL): what makes T-ALL TYK?

scientific article

The CD2-scl transgene alters the phenotype and frequency of T-lymphomas in N-ras transgenic or p53 deficient mice.

scientific article published in December 1997

The Hedgehog receptor Patched1 regulates myeloid and lymphoid progenitors by distinct cell-extrinsic mechanisms.

scientific article

The Lmo2 oncogene initiates leukemia in mice by inducing thymocyte self-renewal

scientific article

The addition of allogeneic peripheral blood-derived progenitor cells to bone marrow for transplantation: results of a randomised clinical trial

scientific article published on 01 August 1999

The clonal evolution of leukemic stem cells in T-cell acute lymphoblastic leukemia.

scientific article published on July 2014

The critical regulator of embryonic hematopoiesis, SCL, is vital in the adult for megakaryopoiesis, erythropoiesis, and lineage choice in CFU-S12

scientific journal article

The fusion partner specifies the oncogenic potential of NUP98 fusion proteins

scientific article published on 21 September 2013

The generation and properties of human macrophage populations from hemopoietic stem cells.

scientific article published on 30 January 2009

The molecular basis of Lmo2-induced T-cell acute lymphoblastic leukemia.

scientific article published on 22 September 2010

The thymus under siege: Lmo2 induces precancerous stem cells in a mouse model of T-ALL.

scientific article published on 15 June 2010

Underestimation of myelodysplastic syndrome incidence by cancer registries: Results from a population-based data linkage study.

scientific article

ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling.

scientific article

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