List of works - Krista Fischer

Genetic studies of body mass index yield new insights for obesity biology

scientific article

Discovery and refinement of loci associated with lipid levels

scientific article

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

scientific article

Systematic identification of trans eQTLs as putative drivers of known disease associations

scientific article (publication date: October 2013)

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

Large-scale association analysis identifies new risk loci for coronary artery disease

scientific article published on 02 December 2012

New genetic loci link adipose and insulin biology to body fat distribution

scientific article

Identification of seven loci affecting mean telomere length and their association with disease

scientific article published on April 2013

GWAS of 126,559 individuals identifies genetic variants associated with educational attainment

scientific article published on 21 June 2013

Common variants associated with plasma triglycerides and risk for coronary artery disease

scientific article

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

FTO genotype is associated with phenotypic variability of body mass index

scientific article published on 16 September 2012

Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity

scientific article published on 21 December 2016

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

scientific article

Seventy-five genetic loci influencing the human red blood cell

scientific article published on 5 December 2012

The prevalence of metabolic syndrome and metabolically healthy obesity in Europe: a collaborative analysis of ten large cohort studies

scientific article

Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways

scientific article

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

scientific article published on 14 April 2013

Biomarker profiling by nuclear magnetic resonance spectroscopy for the prediction of all-cause mortality: an observational study of 17,345 persons

scientific article

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age.

scientific article

The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis

scientific article (publication date: 2013)

Cohort Profile: Estonian Biobank of the Estonian Genome Center, University of Tartu

scientific article

Identification of miR-374a as a prognostic marker for survival in patients with early-stage nonsmall cell lung cancer

scientific article

KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference

scientific article

Leukocyte telomere length associates with prospective mortality independent of immune-related parameters and known genetic markers

scientific article

Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption

scientific article

Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa.

scientific article

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

scientific article published on 9 April 2018

A metabolic view on menopause and ageing

scientific article published on 21 August 2014

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits

scientific article

Adiposity as a cause of cardiovascular disease: a Mendelian randomization study

scientific article

Evidence of inbreeding depression on human height

scientific article

Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity

scientific article published on 13 October 2017

Education and coronary heart disease: mendelian randomisation study

scientific article published on 30 August 2017

Methylation markers of early-stage non-small cell lung cancer

scientific article

Results from the Estonian postmenopausal hormone therapy trial [ISRCTN35338757].

scientific article

Variants near CHRNA3/5 and APOE have age- and sex-related effects on human lifespan

scientific article

Genetic evidence of assortative mating in humans

scholarly article

High-sensitivity C-reactive protein affects central haemodynamics and augmentation index in apparently healthy persons

scientific article published in June 2004

Age- and sex-specific causal effects of adiposity on cardiovascular risk factors

scientific article published on 23 February 2015

A genome-wide association study of early menopause and the combined impact of identified variants

scientific article published on 9 January 2013

High prevalence of blood-borne virus infections and high-risk behaviour among injecting drug users in Tallinn, Estonia

scientific article

Personalized risk prediction for type 2 diabetes: the potential of genetic risk scores

scientific article published on 11 August 2016

Genetic variants linked to education predict longevity

scientific article (publication date: 22 November 2016)

Pathogenic implications for autoimmune mechanisms derived by comparative eQTL analysis of CD4+ versus CD8+ T cells

scientific article

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

scientific article published in November 2018

Characterization of the antioxidant profile of human saliva in peri-implant health and disease

scientific article published in February 2007

Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms

scientific article published on 28 December 2016

Whole-exome sequencing identifies a polymorphism in the BMP5 gene associated with SSRI treatment response in major depression

scientific article published on 7 August 2013

List of works by Krista Fischer

Genetic studies of body mass index yield new insights for obesity biology

Discovery and refinement of loci associated with lipid levels

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

Systematic identification of trans eQTLs as putative drivers of known disease associations

Defining the role of common variation in the genomic and biological architecture of adult human height

Large-scale association analysis identifies new risk loci for coronary artery disease

New genetic loci link adipose and insulin biology to body fat distribution

Identification of seven loci affecting mean telomere length and their association with disease

GWAS of 126,559 individuals identifies genetic variants associated with educational attainment

Common variants associated with plasma triglycerides and risk for coronary artery disease

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

FTO genotype is associated with phenotypic variability of body mass index

Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

Seventy-five genetic loci influencing the human red blood cell

The prevalence of metabolic syndrome and metabolically healthy obesity in Europe: a collaborative analysis of ten large cohort studies

Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

Biomarker profiling by nuclear magnetic resonance spectroscopy for the prediction of all-cause mortality: an observational study of 17,345 persons

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age.

The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis

Cohort Profile: Estonian Biobank of the Estonian Genome Center, University of Tartu

Identification of miR-374a as a prognostic marker for survival in patients with early-stage nonsmall cell lung cancer

KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference

Leukocyte telomere length associates with prospective mortality independent of immune-related parameters and known genetic markers

Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption

Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa.

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes

A metabolic view on menopause and ageing

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits

Adiposity as a cause of cardiovascular disease: a Mendelian randomization study

Evidence of inbreeding depression on human height

Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity

Education and coronary heart disease: mendelian randomisation study

Methylation markers of early-stage non-small cell lung cancer

Results from the Estonian postmenopausal hormone therapy trial [ISRCTN35338757].

Variants near CHRNA3/5 and APOE have age- and sex-related effects on human lifespan

Genetic evidence of assortative mating in humans

High-sensitivity C-reactive protein affects central haemodynamics and augmentation index in apparently healthy persons

Age- and sex-specific causal effects of adiposity on cardiovascular risk factors

A genome-wide association study of early menopause and the combined impact of identified variants

High prevalence of blood-borne virus infections and high-risk behaviour among injecting drug users in Tallinn, Estonia

Personalized risk prediction for type 2 diabetes: the potential of genetic risk scores

Genetic variants linked to education predict longevity

Pathogenic implications for autoimmune mechanisms derived by comparative eQTL analysis of CD4+ versus CD8+ T cells

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

Characterization of the antioxidant profile of human saliva in peri-implant health and disease

Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms

Whole-exome sequencing identifies a polymorphism in the BMP5 gene associated with SSRI treatment response in major depression