List of works by Krista Fischer

A genome-wide association study of early menopause and the combined impact of identified variants

scientific article published on 9 January 2013

A metabolic profile of all-cause mortality risk identified in an observational study of 44,168 individuals

scientific article published on 20 August 2019

A metabolic view on menopause and ageing

scientific article published on 21 August 2014

A principal component meta-analysis on multiple anthropometric traits identifies novel loci for body shape

scientific article published on 23 November 2016

A rare-variant test for high-dimensional data

scientific article

Adiposity as a cause of cardiovascular disease: a Mendelian randomization study

scientific article

Age- and sex-specific causal effects of adiposity on cardiovascular risk factors

scientific article published on 23 February 2015

Arsenic and gallbladder cancer risk: Mendelian randomization analysis of European prospective data

scientific article published on 31 December 2019

Association of branched-chain amino acids and other circulating metabolites with risk of incident dementia and Alzheimer's disease: A prospective study in eight cohorts.

scientific article published on 28 February 2018

Associations of autozygosity with a broad range of human phenotypes

scientific article published on 31 October 2019

Biomarker profiling by nuclear magnetic resonance spectroscopy for the prediction of all-cause mortality: an observational study of 17,345 persons

scientific article

Cardiovascular Risk Factors and Ischemic Heart Disease: Is the Confluence of Risk Factors Greater Than the Parts? A Genetic Approach

scientific article published on 21 April 2016

Characterization of the antioxidant profile of human saliva in peri-implant health and disease

scientific article published in February 2007

Circulating metabolites and general cognitive ability and dementia: Evidence from 11 cohort studies

scientific article

Cohort Profile: Estonian Biobank of the Estonian Genome Center, University of Tartu

scientific article

Common variants associated with plasma triglycerides and risk for coronary artery disease

scientific article

Comparing distributions of polygenic risk scores of type 2 diabetes and coronary heart disease within different populations

scientific article

Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms

scientific article published on 28 December 2016

Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms

Correction: Methylation Markers of Early-Stage Non-Small Cell Lung Cancer

scientific article published on 20 January 2017

Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

Correlation of peri-implant health and myeloperoxidase levels: a cross-sectional clinical study.

scientific article published in October 2004

Correlations between clinical parameters and interleukin-6 and interleukin-10 levels in saliva from totally edentulous patients with peri-implant disease.

scientific article published in July 2006

Defining the role of common variation in the genomic and biological architecture of adult human height

scientific article

Discovery and refinement of loci associated with lipid levels

scientific article

Education and coronary heart disease: mendelian randomisation study

scientific article published on 30 August 2017

Effect of antihypertensive treatment with candesartan or amlodipine on glutathione and its redox status, homocysteine and vitamin concentrations in patients with essential hypertension

scientific article published in January 2005

Effect of characteristics of women on attendance in blind and non-blind randomised trials: analysis of recruitment data from the EPHT Trial

scientific article

Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity

scientific article published on 21 December 2016

Evidence of inbreeding depression on human height

scientific article

FTO genotype is associated with phenotypic variability of body mass index

scientific article published on 16 September 2012

Fine-mapping of an expanded set of type 2 diabetes loci to single-variant resolution using high-density imputation and islet-specific epigenome maps

GWAS of 126,559 individuals identifies genetic variants associated with educational attainment

scientific article published on 21 June 2013

Gallstones, Body Mass Index, C-reactive Protein and Gallbladder Cancer - Mendelian Randomization Analysis of Chilean and European Genotype Data

scientific article published on 06 September 2020

Genetic evidence of assortative mating in humans

article

Genetic studies of body mass index yield new insights for obesity biology

scientific article

Genetic variants linked to education predict longevity

scientific article (publication date: 22 November 2016)

Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders

scientific article published in November 2018

Genome-Wide Association Study Reveals First Locus for Anorexia Nervosa and Metabolic Correlations

scholarly article

Genome-wide association meta-analysis of human longevity identifies a novel locus conferring survival beyond 90 years of age.

scientific article

Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa.

scientific article

Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity

scientific article published on 13 October 2017

Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture

scientific journal article

Genome-wide meta-analysis identifies six novel loci associated with habitual coffee consumption

scientific article

Genome-wide meta-analysis of 241,258 adults accounting for smoking behaviour identifies novel loci for obesity traits.

scientific article

Genome-wide meta-analysis of common variant differences between men and women

scientific article published on 27 July 2012

Genomics of 1 million parent lifespans implicates novel pathways and common diseases and distinguishes survival chances

Glycosylation of immunoglobulin G is regulated by a large network of genes pleiotropic with inflammatory diseases

scientific article published on 19 February 2020

High prevalence of blood-borne virus infections and high-risk behaviour among injecting drug users in Tallinn, Estonia

scientific article

High-sensitivity C-reactive protein affects central haemodynamics and augmentation index in apparently healthy persons

scientific article published in June 2004

Homocysteine and red blood cell glutathione as indices for middle-aged untreated essential hypertension patients

scientific article

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders

scientific article published on 14 April 2013

Identification of miR-374a as a prognostic marker for survival in patients with early-stage nonsmall cell lung cancer

scientific article

Identification of seven loci affecting mean telomere length and their association with disease

scientific article published on April 2013

KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference

scientific article

Large-scale association analysis identifies new risk loci for coronary artery disease

scientific article published on 02 December 2012

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

scientific article

Leukocyte telomere length associates with prospective mortality independent of immune-related parameters and known genetic markers

scientific article

MARV: a tool for genome-wide multi-phenotype analysis of rare variants

scientific article

Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways

scientific article

Metabolomics reveals a link between homocysteine and lipid metabolism and leukocyte telomere length: the ENGAGE consortium

scientific article published on 12 August 2019

Methylation markers of early-stage non-small cell lung cancer

scientific article

MixFit: Methodology for Computing Ancestry-Related Genetic Scores at the Individual Level and Its Application to the Estonian and Finnish Population Studies

scientific article

New genetic loci link adipose and insulin biology to body fat distribution

scientific article

Pathogenic implications for autoimmune mechanisms derived by comparative eQTL analysis of CD4+ versus CD8+ T cells

scientific article

Personalized risk prediction for type 2 diabetes: the potential of genetic risk scores

scientific article published on 11 August 2016

Refining The Accuracy Of Validated Target Identification Through Coding Variant Fine-Mapping In Type 2 Diabetes

article

Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes.

scientific article published on 9 April 2018

RegScan: a GWAS tool for quick estimation of allele effects on continuous traits and their combinations

scientific article published on 5 September 2013

Results from a blind and a non-blind randomised trial run in parallel: experience from the Estonian Postmenopausal Hormone Therapy (EPHT) Trial

scientific article

Results from the Estonian postmenopausal hormone therapy trial [ISRCTN35338757].

scientific article

SCOPA and META-SCOPA: software for the analysis and aggregation of genome-wide association studies of multiple correlated phenotypes

scientific article

Seventy-five genetic loci influencing the human red blood cell

scientific article published on 5 December 2012

Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits

scientific article

Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies

scientific article published on 16 February 2020

Surveillance of HIV, hepatitis B virus, and hepatitis C virus in an estonian injection drug-using population: sensitivity and specificity of testing syringes for public health surveillance

scientific article

Symptom reporting and quality of life in the Estonian Postmenopausal Hormone Therapy Trial

scientific article

Systematic identification of trans eQTLs as putative drivers of known disease associations

scientific article (publication date: October 2013)

The 1st year of the COVID-19 epidemic in Estonia: a population-based nationwide sequential/consecutive cross-sectional study

scientific article published on 09 February 2022

The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study

scientific article

The prevalence of metabolic syndrome and metabolically healthy obesity in Europe: a collaborative analysis of ten large cohort studies

scientific article

The relationship between inflammation and arterial stiffness in patients with essential hypertension

scientific article

The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis

scientific article (publication date: 2013)

Variants near CHRNA3/5 and APOE have age- and sex-related effects on human lifespan

scientific article

Whole-exome sequencing identifies a polymorphism in the BMP5 gene associated with SSRI treatment response in major depression.

scientific article published on 7 August 2013

Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019: a pooled analysis of 1201 population-representative studies with 104 million participants

scholarly article

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